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The map label for this gene is yqhT [H]

Identifier: 52786355

GI number: 52786355

Start: 2532742

End: 2533803

Strand: Reverse

Name: yqhT [H]

Synonym: BLi02617

Alternate gene names: 52786355

Gene position: 2533803-2532742 (Counterclockwise)

Preceding gene: 52786356

Following gene: 52786354

Centisome position: 60.01

GC content: 48.49

Gene sequence:

>1062_bases
ATGAAACTAAACAAATTGAGAGAGCTTTTCGGCGGTTTAGGCATTGACGGTATATTGGTGACGAGCGGCGTTAATTTGCG
GTACATCACCGGATTTACCGGATCTTCAGGACTGGCGGTCATCTCAGACGATCAAGCAGTCTTTATTACGGATTTCCGCT
ATACAGAACAGGCGAAGGATCAAATCAAAAGCTTTGACATCGTTCAGCATGCCGGCGGAATCGTTCAAAAGACCGCCGAA
GTGATCAAAGAGATGGGGATAAACAAAATCGGTTTTGAACAGGATAAAATGACATACGGAACGTATGCCGCCTACAAAGA
GCAGCTTGGCGCAGCTGAACTCGTTCCCGTTTCTCAATCTGTGGAAAAGTTGCGCTTGATTAAGTCAAGTGAAGAGATTA
AGATATTAAAGGAAGCTGCAAAGATTGCAGATGATGCATTCAGCCATATTCTGACGGTCATCAAGCCCGGCATCACCGAA
ATTGAAGTCGCCAATGAGCTCGAGTTTTACATGCGGAGCCAGGGAGCCGATCATTCGTCCTTCGATATGATCGTGGCGTC
AGGCGTACGCTCAAGTCTGCCGCACGGAGTGGCAAGCGGCAAAGCGATCGAGAAAGGCGACCTTGTGACGCTGGACTTTG
GGGCTTACTATAAAGGTTACTGCTCGGACATTACGCGTACAGTCGCGGTAGGAGAGCCGGATGATGAGCTGAAACGCATT
TATCAAACCGTGTTTGAGGCGCAGGCTATCGGCATGCGGAGCATCAAGCCGGGAATCACCGGGAAACAGGCTGACGCATA
CACAAGGGACTACATATCTTCACAAGGCTACGGCGATTATTTCGGCCATTCAACAGGCCATGGCCTCGGCATGGAAGTTC
ATGAAAGTCCGGCGCTTTCAGCACGTTCTGACCAGATGCTTGAAAAAGGCATGGTTGTAACGGTTGAACCGGGAATTTAC
ATACCGGGCAAAGGCGGGGTCAGGATAGAAGATGATATTGTCCTGACAGAGGAAGGAAACGAATCCCTTACCCATTCCGC
GAAAGATTTAATTATTTTATAA

Upstream 100 bases:

>100_bases
GGTTGCAAGAGGCCAGATCACCGGACTCGGCTTTGAAGGTTATAAGCTGGCCATCTCTTATTTTATGAACACAAATAACA
AATAGGGGGACTAGTGGACA

Downstream 100 bases:

>100_bases
TCCGTTTGATTGGAGCAATAGGAGGATAATCATGATTTCAGTAAACGATTTTCGCACAGGTTTAACGATTGAAGTAGACG
GAGGGATTTGGCGCGTTGTT

Product: YqhT

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MKLNKLRELFGGLGIDGILVTSGVNLRYITGFTGSSGLAVISDDQAVFITDFRYTEQAKDQIKSFDIVQHAGGIVQKTAE
VIKEMGINKIGFEQDKMTYGTYAAYKEQLGAAELVPVSQSVEKLRLIKSSEEIKILKEAAKIADDAFSHILTVIKPGITE
IEVANELEFYMRSQGADHSSFDMIVASGVRSSLPHGVASGKAIEKGDLVTLDFGAYYKGYCSDITRTVAVGEPDDELKRI
YQTVFEAQAIGMRSIKPGITGKQADAYTRDYISSQGYGDYFGHSTGHGLGMEVHESPALSARSDQMLEKGMVVTVEPGIY
IPGKGGVRIEDDIVLTEEGNESLTHSAKDLIIL

Sequences:

>Translated_353_residues
MKLNKLRELFGGLGIDGILVTSGVNLRYITGFTGSSGLAVISDDQAVFITDFRYTEQAKDQIKSFDIVQHAGGIVQKTAE
VIKEMGINKIGFEQDKMTYGTYAAYKEQLGAAELVPVSQSVEKLRLIKSSEEIKILKEAAKIADDAFSHILTVIKPGITE
IEVANELEFYMRSQGADHSSFDMIVASGVRSSLPHGVASGKAIEKGDLVTLDFGAYYKGYCSDITRTVAVGEPDDELKRI
YQTVFEAQAIGMRSIKPGITGKQADAYTRDYISSQGYGDYFGHSTGHGLGMEVHESPALSARSDQMLEKGMVVTVEPGIY
IPGKGGVRIEDDIVLTEEGNESLTHSAKDLIIL
>Mature_353_residues
MKLNKLRELFGGLGIDGILVTSGVNLRYITGFTGSSGLAVISDDQAVFITDFRYTEQAKDQIKSFDIVQHAGGIVQKTAE
VIKEMGINKIGFEQDKMTYGTYAAYKEQLGAAELVPVSQSVEKLRLIKSSEEIKILKEAAKIADDAFSHILTVIKPGITE
IEVANELEFYMRSQGADHSSFDMIVASGVRSSLPHGVASGKAIEKGDLVTLDFGAYYKGYCSDITRTVAVGEPDDELKRI
YQTVFEAQAIGMRSIKPGITGKQADAYTRDYISSQGYGDYFGHSTGHGLGMEVHESPALSARSDQMLEKGMVVTVEPGIY
IPGKGGVRIEDDIVLTEEGNESLTHSAKDLIIL

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI11559925, Length=254, Percent_Identity=33.8582677165354, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI260593665, Length=285, Percent_Identity=28.7719298245614, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI149589008, Length=285, Percent_Identity=28.7719298245614, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI260593663, Length=299, Percent_Identity=27.4247491638796, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI264681563, Length=194, Percent_Identity=33.5051546391753, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI93141226, Length=176, Percent_Identity=32.3863636363636, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI164420681, Length=262, Percent_Identity=24.4274809160305, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI264681565, Length=191, Percent_Identity=31.9371727748691, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1788728, Length=357, Percent_Identity=40.6162464985994, Blast_Score=269, Evalue=2e-73,
Organism=Escherichia coli, GI1789275, Length=333, Percent_Identity=30.9309309309309, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1786364, Length=254, Percent_Identity=24.8031496062992, Blast_Score=77, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17508215, Length=294, Percent_Identity=25.8503401360544, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17509539, Length=186, Percent_Identity=34.9462365591398, Blast_Score=81, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI71996291, Length=251, Percent_Identity=25.0996015936255, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6321118, Length=297, Percent_Identity=26.2626262626263, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6320922, Length=253, Percent_Identity=27.2727272727273, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6323273, Length=268, Percent_Identity=26.1194029850746, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322999, Length=175, Percent_Identity=33.1428571428571, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19920384, Length=322, Percent_Identity=29.8136645962733, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI21357079, Length=294, Percent_Identity=28.9115646258503, Blast_Score=105, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 38340; Mature: 38340

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS00491 PROLINE_PEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLNKLRELFGGLGIDGILVTSGVNLRYITGFTGSSGLAVISDDQAVFITDFRYTEQAKD
CCHHHHHHHHCCCCCCCEEEECCCCEEEEEEECCCCCEEEEECCCEEEEEECCHHHHHHH
QIKSFDIVQHAGGIVQKTAEVIKEMGINKIGFEQDKMTYGTYAAYKEQLGAAELVPVSQS
HHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEHHHH
VEKLRLIKSSEEIKILKEAAKIADDAFSHILTVIKPGITEIEVANELEFYMRSQGADHSS
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHCCCCCCH
FDMIVASGVRSSLPHGVASGKAIEKGDLVTLDFGAYYKGYCSDITRTVAVGEPDDELKRI
HHHHHHHHHHHHCCCCCCCCCEECCCCEEEEECCCHHHHHHHHHHHEEECCCCHHHHHHH
YQTVFEAQAIGMRSIKPGITGKQADAYTRDYISSQGYGDYFGHSTGHGLGMEVHESPALS
HHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCCCCC
ARSDQMLEKGMVVTVEPGIYIPGKGGVRIEDDIVLTEEGNESLTHSAKDLIIL
CCHHHHHHCCCEEEECCCEEECCCCCCEEECCEEEECCCCCHHHHCCCCEEEC
>Mature Secondary Structure
MKLNKLRELFGGLGIDGILVTSGVNLRYITGFTGSSGLAVISDDQAVFITDFRYTEQAKD
CCHHHHHHHHCCCCCCCEEEECCCCEEEEEEECCCCCEEEEECCCEEEEEECCHHHHHHH
QIKSFDIVQHAGGIVQKTAEVIKEMGINKIGFEQDKMTYGTYAAYKEQLGAAELVPVSQS
HHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEHHHH
VEKLRLIKSSEEIKILKEAAKIADDAFSHILTVIKPGITEIEVANELEFYMRSQGADHSS
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHCCCCCCH
FDMIVASGVRSSLPHGVASGKAIEKGDLVTLDFGAYYKGYCSDITRTVAVGEPDDELKRI
HHHHHHHHHHHHCCCCCCCCCEECCCCEEEEECCCHHHHHHHHHHHEEECCCCHHHHHHH
YQTVFEAQAIGMRSIKPGITGKQADAYTRDYISSQGYGDYFGHSTGHGLGMEVHESPALS
HHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCCCCC
ARSDQMLEKGMVVTVEPGIYIPGKGGVRIEDDIVLTEEGNESLTHSAKDLIIL
CCHHHHHHCCCEEEECCCEEECCCCCCEEECCEEEECCCCCHHHHCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]