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The map label for this gene is yqjD [H]

Identifier: 52786310

GI number: 52786310

Start: 2490952

End: 2492481

Strand: Reverse

Name: yqjD [H]

Synonym: BLi02572

Alternate gene names: 52786310

Gene position: 2492481-2490952 (Counterclockwise)

Preceding gene: 52786311

Following gene: 52786309

Centisome position: 59.03

GC content: 52.48

Gene sequence:

>1530_bases
ATGAATATGTTTGAAAGAGTCGACGATTTAAACAACAGCCGCCAAAAAGCTTCGCTCGGAGGCGGCCAGGAACGGATCGA
CAGGCAGAAGCAAAAAGGCAAGCTCACCGCCAGAGAACGAATTGATCTTCTGCTTGATGAGGGGACGTTCACTGAACTGA
ATGCCTTTGCCAGAAGCCGGCAGTCCGGCGGCCCGTTAGGCGACGGGGTTGTCACGGGATTCGGAAAGATCGACGGGCGG
CCCGTTTATCTATTTTCCCAGGATTTTACCGTCACCGGCGGAGCGCTCGGAGAAATGCACGCCAAAAAAATAGCGGCCGT
CATGGATCTTGCCCTCAAAAATAAGGCGCCGTTCATCGGTCTGAACGACTCAGGTGGTGCGAGAATTCAAGAGGGTGTGC
TATCATTAGATGGATACGGTCATATTTTTTACCGAAATGTCCTTTGCTCAGGCATCATTCCGCAAATCTCTGTCATTCTC
GGCCCTTGTGCGGGCGGCGCGGTTTATTCCCCCGCTTTGACCGACTTCGTTTTCATGAGCGAAAAAACCGGACAGATGTT
TATTACCGGTCCGAAAGTCATCAAAACGGCGACAGGCGAGGCTGTCAGCTCCGGTGAATTGGGGGGCGCCTATATACATA
ATTCAATCAGCGGGAATGCCCATTTTTCCGGGGATTCCGATGAGGCCGTCCTCCATGAGGTGCGCAAGCTCTTGTCCTAC
ATCCTCCAGAATCACGAAGAAAAGCCTCCCGCCAAGGCGAGAAAGGCGAAAGATCATGAGATAAGGCCTGCTTTAATGAC
GATCCTGCCTGAAGACGGTCAGCGTCCGTATGACGTCAAACAGATCATCGCGGAAATCGCAGACGGCGGAACATTTTTTG
AAGTGCAGTGCCATTTTGCCAAAAACGCGGTGATCGGTTTTGCAAGGATAGCGGGGGAAACGGCGGCGGTCGTGGCCAAC
CAGCCGAAGTATTTAGCCGGAAGCCTCAGCATGGATGCGGCTGACAAAATCGCCCGGTTTATCCGTTTTTGCGATTCCTT
TCAGATCCCGATTTTGACTTTGGTTGATTGTCCCGGTTTTCTTCCGGGAATACGCGAAGAGCACGGCGGGGTGATCAGGC
ACGGCGCCAAAATCCTTTACGCGTATGCGGAAGCCACTGTCAGCAAGGTGACGGTCATTTTAAGAAAAGCATACGGCGGA
GCATATGTCGCTTTAAACAGCAAGGCGCTTGGAGCGGATGCCGTGTTTGCGTGGCCGAATGCAGAAATTGCAGTGATGGG
CGCCTCGGAAGCTGCAGACGTGCTGTTTGCGAAGGAAATCGAACGGTCAGACGACCCGCGGGCCGCCCGGGAGGAAAAAA
TCCGGAAGTGCATGCAGGCTTCAAGCCCTTTTACCGCTGCAAGATACGGCATGGTTGACGATATCATCGATCCGAAAGAG
ACGCGGAAGAAGCTGATCCAAACGTTTGACATGCTGAAGAGCAAAAAAGAAATCCGGCTGGACAAAAAGCATGGAAATAT
ACCGCTTTAA

Upstream 100 bases:

>100_bases
GCTTTTCACCTCTGTTTTTTAATCTCCCATTATTTTATACTGCTTTTTTTCATCGGACAAGTTTCGTTCTTGGAATCAAA
TAGAGAAGGGGCAGAACGTG

Downstream 100 bases:

>100_bases
AAAATGGAGGGGAAACTAGTATGAATAAAAAACGCTTGTTAGAAGAGTTTTTAGAACTTGTGCAAATTGATTCCGAGACA
AAACATGAAGCTGAAATCTG

Product: YqjD

Products: NA

Alternate protein names: PCCase; Propanoyl-CoA:carbon dioxide ligase [H]

Number of amino acids: Translated: 509; Mature: 509

Protein sequence:

>509_residues
MNMFERVDDLNNSRQKASLGGGQERIDRQKQKGKLTARERIDLLLDEGTFTELNAFARSRQSGGPLGDGVVTGFGKIDGR
PVYLFSQDFTVTGGALGEMHAKKIAAVMDLALKNKAPFIGLNDSGGARIQEGVLSLDGYGHIFYRNVLCSGIIPQISVIL
GPCAGGAVYSPALTDFVFMSEKTGQMFITGPKVIKTATGEAVSSGELGGAYIHNSISGNAHFSGDSDEAVLHEVRKLLSY
ILQNHEEKPPAKARKAKDHEIRPALMTILPEDGQRPYDVKQIIAEIADGGTFFEVQCHFAKNAVIGFARIAGETAAVVAN
QPKYLAGSLSMDAADKIARFIRFCDSFQIPILTLVDCPGFLPGIREEHGGVIRHGAKILYAYAEATVSKVTVILRKAYGG
AYVALNSKALGADAVFAWPNAEIAVMGASEAADVLFAKEIERSDDPRAAREEKIRKCMQASSPFTAARYGMVDDIIDPKE
TRKKLIQTFDMLKSKKEIRLDKKHGNIPL

Sequences:

>Translated_509_residues
MNMFERVDDLNNSRQKASLGGGQERIDRQKQKGKLTARERIDLLLDEGTFTELNAFARSRQSGGPLGDGVVTGFGKIDGR
PVYLFSQDFTVTGGALGEMHAKKIAAVMDLALKNKAPFIGLNDSGGARIQEGVLSLDGYGHIFYRNVLCSGIIPQISVIL
GPCAGGAVYSPALTDFVFMSEKTGQMFITGPKVIKTATGEAVSSGELGGAYIHNSISGNAHFSGDSDEAVLHEVRKLLSY
ILQNHEEKPPAKARKAKDHEIRPALMTILPEDGQRPYDVKQIIAEIADGGTFFEVQCHFAKNAVIGFARIAGETAAVVAN
QPKYLAGSLSMDAADKIARFIRFCDSFQIPILTLVDCPGFLPGIREEHGGVIRHGAKILYAYAEATVSKVTVILRKAYGG
AYVALNSKALGADAVFAWPNAEIAVMGASEAADVLFAKEIERSDDPRAAREEKIRKCMQASSPFTAARYGMVDDIIDPKE
TRKKLIQTFDMLKSKKEIRLDKKHGNIPL
>Mature_509_residues
MNMFERVDDLNNSRQKASLGGGQERIDRQKQKGKLTARERIDLLLDEGTFTELNAFARSRQSGGPLGDGVVTGFGKIDGR
PVYLFSQDFTVTGGALGEMHAKKIAAVMDLALKNKAPFIGLNDSGGARIQEGVLSLDGYGHIFYRNVLCSGIIPQISVIL
GPCAGGAVYSPALTDFVFMSEKTGQMFITGPKVIKTATGEAVSSGELGGAYIHNSISGNAHFSGDSDEAVLHEVRKLLSY
ILQNHEEKPPAKARKAKDHEIRPALMTILPEDGQRPYDVKQIIAEIADGGTFFEVQCHFAKNAVIGFARIAGETAAVVAN
QPKYLAGSLSMDAADKIARFIRFCDSFQIPILTLVDCPGFLPGIREEHGGVIRHGAKILYAYAEATVSKVTVILRKAYGG
AYVALNSKALGADAVFAWPNAEIAVMGASEAADVLFAKEIERSDDPRAAREEKIRKCMQASSPFTAARYGMVDDIIDPKE
TRKKLIQTFDMLKSKKEIRLDKKHGNIPL

Specific function: This Protein Is A Component Of The Acetyl Coenzyme A Carboxylase Complex; First, Biotin Carboxylase Catalyzes The Carboxylation Of The Carrier Protein And Then The Transcarboxylase Transfers The Carboxyl Group To Form Malonyl-CoA. [C]

COG id: COG4799

COG function: function code I; Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI119943100, Length=508, Percent_Identity=51.5748031496063, Blast_Score=509, Evalue=1e-144,
Organism=Homo sapiens, GI295821216, Length=528, Percent_Identity=49.6212121212121, Blast_Score=498, Evalue=1e-141,
Organism=Homo sapiens, GI11545863, Length=513, Percent_Identity=33.7231968810916, Blast_Score=234, Evalue=2e-61,
Organism=Escherichia coli, GI1788655, Length=222, Percent_Identity=25.6756756756757, Blast_Score=70, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI25147362, Length=506, Percent_Identity=52.5691699604743, Blast_Score=518, Evalue=1e-147,
Organism=Caenorhabditis elegans, GI25147359, Length=506, Percent_Identity=52.5691699604743, Blast_Score=517, Evalue=1e-147,
Organism=Caenorhabditis elegans, GI17552936, Length=509, Percent_Identity=33.0058939096267, Blast_Score=253, Evalue=2e-67,
Organism=Drosophila melanogaster, GI24586065, Length=521, Percent_Identity=34.1650671785029, Blast_Score=251, Evalue=1e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011763
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =6.4.1.3 [H]

Molecular weight: Translated: 55154; Mature: 55154

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: PS50980 COA_CT_NTER ; PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMFERVDDLNNSRQKASLGGGQERIDRQKQKGKLTARERIDLLLDEGTFTELNAFARSR
CCHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHCCCCHHHHHHEEECCCCHHHHHHHHHHH
QSGGPLGDGVVTGFGKIDGRPVYLFSQDFTVTGGALGEMHAKKIAAVMDLALKNKAPFIG
CCCCCCCCCCEECCCCCCCEEEEEEECCCEECCCCHHHHHHHHHHHHHHHHHCCCCCEEE
LNDSGGARIQEGVLSLDGYGHIFYRNVLCSGIIPQISVILGPCAGGAVYSPALTDFVFMS
ECCCCCCHHHHCCEECCCCCHHHHHHHHHHCCHHHHHHHEECCCCCCCCCHHHHHHEEEE
EKTGQMFITGPKVIKTATGEAVSSGELGGAYIHNSISGNAHFSGDSDEAVLHEVRKLLSY
CCCCCEEEECCCEEEECCCCCCCCCCCCCCEEECCCCCCEEECCCCCHHHHHHHHHHHHH
ILQNHEEKPPAKARKAKDHEIRPALMTILPEDGQRPYDVKQIIAEIADGGTFFEVQCHFA
HHHCCCCCCCHHHHCCCCCCCCCHHEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEEEEC
KNAVIGFARIAGETAAVVANQPKYLAGSLSMDAADKIARFIRFCDSFQIPILTLVDCPGF
CCHHHHHHHHCCCCEEEEECCCCCEECCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCC
LPGIREEHGGVIRHGAKILYAYAEATVSKVTVILRKAYGGAYVALNSKALGADAVFAWPN
CCCCHHHCCCEECCCHHHEEHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEECCC
AEIAVMGASEAADVLFAKEIERSDDPRAAREEKIRKCMQASSPFTAARYGMVDDIIDPKE
CCEEEEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHCCCHHHCCCCHH
TRKKLIQTFDMLKSKKEIRLDKKHGNIPL
HHHHHHHHHHHHHCHHHHEEECCCCCCCC
>Mature Secondary Structure
MNMFERVDDLNNSRQKASLGGGQERIDRQKQKGKLTARERIDLLLDEGTFTELNAFARSR
CCHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHCCCCHHHHHHEEECCCCHHHHHHHHHHH
QSGGPLGDGVVTGFGKIDGRPVYLFSQDFTVTGGALGEMHAKKIAAVMDLALKNKAPFIG
CCCCCCCCCCEECCCCCCCEEEEEEECCCEECCCCHHHHHHHHHHHHHHHHHCCCCCEEE
LNDSGGARIQEGVLSLDGYGHIFYRNVLCSGIIPQISVILGPCAGGAVYSPALTDFVFMS
ECCCCCCHHHHCCEECCCCCHHHHHHHHHHCCHHHHHHHEECCCCCCCCCHHHHHHEEEE
EKTGQMFITGPKVIKTATGEAVSSGELGGAYIHNSISGNAHFSGDSDEAVLHEVRKLLSY
CCCCCEEEECCCEEEECCCCCCCCCCCCCCEEECCCCCCEEECCCCCHHHHHHHHHHHHH
ILQNHEEKPPAKARKAKDHEIRPALMTILPEDGQRPYDVKQIIAEIADGGTFFEVQCHFA
HHHCCCCCCCHHHHCCCCCCCCCHHEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEEEEC
KNAVIGFARIAGETAAVVANQPKYLAGSLSMDAADKIARFIRFCDSFQIPILTLVDCPGF
CCHHHHHHHHCCCCEEEEECCCCCEECCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCC
LPGIREEHGGVIRHGAKILYAYAEATVSKVTVILRKAYGGAYVALNSKALGADAVFAWPN
CCCCHHHCCCEECCCHHHEEHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEECCC
AEIAVMGASEAADVLFAKEIERSDDPRAAREEKIRKCMQASSPFTAARYGMVDDIIDPKE
CCEEEEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHCCCHHHCCCCHH
TRKKLIQTFDMLKSKKEIRLDKKHGNIPL
HHHHHHHHHHHHHCHHHHEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]