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The map label for this gene is yqjH [H]

Identifier: 52786306

GI number: 52786306

Start: 2487155

End: 2488411

Strand: Reverse

Name: yqjH [H]

Synonym: BLi02568

Alternate gene names: 52786306

Gene position: 2488411-2487155 (Counterclockwise)

Preceding gene: 52786309

Following gene: 52786305

Centisome position: 58.93

GC content: 49.72

Gene sequence:

>1257_bases
TTGTCTGCTGATAAACAAAAGGGGAGAGTCATCTTTCATATCGATATGAACAGCTTTTACGCGTCTGTTGAAATGGCGTA
TGACCCTTCGCTGAAAGGCAGGCCGCTAGCCATCGCGGGAAATGCGAAGGAGCGGAAAGGAATCGTCGTCACGTGCAGCT
ATGAGGCGAGAGCACGCGGCGTCAAACCGCCCATGCCGCTCTGGGAAGCGAAGCGGCTCTGTCCCGAGCTGATCGTCAAG
CCGCCGAATTTCGACCGCTACAGAAGCTCTTCAAGAGAAATGTTTCAAGTGCTCAGGGAGTACACGGACCTTGTCGAGCC
TGTTTCGATCGACGAAGGGTACATGGACTTAACGGATACGCCATACAGAAATCGGGCATGCGAAACGGCAAAGGAAATTC
AGGAGCGCCTTCAAAAGGAACTGCTGCTTCCGTCAAGCATCGGGATCGCTCCGAATAAATTCCTGGCCAAAATGGCTTCG
GATATGAAAAAGCCGCTCGGCATTACGATTTTGAGAAAGCGTGAAGTGCCCCGGATTCTTTGGCCCATGGACATCAGCGA
GATGTACGGAGTCGGCCGGAAAACCGCCGAAAAGCTTAAGACGCTCGAGATCGAAAAGATCGGCGATTTGGCTGCCGCAG
ATGAGTATGCTTTAAAGCGCCTCCTCGGCATCAACGGCCCCCGTTTAAAAAGAAGGGCAAACGGCATCGACACAGGAGAA
GTGAATCCCGACAGAATATACGAATTCAAAAGCGTCGGCAATTCCTCGACCCTCCCGCATGACAGCACAGATGAGAAAGA
GCTGTTCGGACTGATTGACAAGCTTTCAATCTCAGTAAGCGACAGGCTGAAGCGAAAAGAGGTCATGGCAGCAAAAGTTT
TCATCATGATCCGCTTTGCGGACTGGACGAACATAACAAGAAGCAAGACCCTTCTGAATCCGACCGATTCAAAAGACGAA
ATTGCGAAGGAATCGAAAGCCCTTTTCAGGCAGCATTGGCACGGAAGCCCTGTCAGGCTTTTGGGCGTGACGGGAACAGA
CCTCGTCAATCGAAAGGAAGCCGTCAAACAGCTTGATTTGTTTTCCTTTCATGAGGATGCCAAAGATGAGCCGATCCAAA
AAGTGATGGCCGAACTGAATGAAAAATATGGAACAGACCTCATCAAAAAAGGGGTCAGGATTGTGAAAAAAGAAAGCAAA
ACGAGCGGAACAAGCTTTAACAAAGATTTTTTCCAAGACGAGAGACAAGATCAATAG

Upstream 100 bases:

>100_bases
TTGAAAGATTCAAGAATCATCTTTTATCACTTCCGTTTCATTTAACATCTTACTATATGAAAGCCGGGATGTCTAATCAG
AGTGCCAGGAGGGAGCCGTT

Downstream 100 bases:

>100_bases
CTTGAAAATGTAGGTCAAAGTGTGGTAATTTCAATTTAAATAAAAATTAAACTATAATGCTAAACGCTTTAGAAGGGACG
TTAGACATGGCAAAACAACA

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV 1 [H]

Number of amino acids: Translated: 418; Mature: 417

Protein sequence:

>418_residues
MSADKQKGRVIFHIDMNSFYASVEMAYDPSLKGRPLAIAGNAKERKGIVVTCSYEARARGVKPPMPLWEAKRLCPELIVK
PPNFDRYRSSSREMFQVLREYTDLVEPVSIDEGYMDLTDTPYRNRACETAKEIQERLQKELLLPSSIGIAPNKFLAKMAS
DMKKPLGITILRKREVPRILWPMDISEMYGVGRKTAEKLKTLEIEKIGDLAAADEYALKRLLGINGPRLKRRANGIDTGE
VNPDRIYEFKSVGNSSTLPHDSTDEKELFGLIDKLSISVSDRLKRKEVMAAKVFIMIRFADWTNITRSKTLLNPTDSKDE
IAKESKALFRQHWHGSPVRLLGVTGTDLVNRKEAVKQLDLFSFHEDAKDEPIQKVMAELNEKYGTDLIKKGVRIVKKESK
TSGTSFNKDFFQDERQDQ

Sequences:

>Translated_418_residues
MSADKQKGRVIFHIDMNSFYASVEMAYDPSLKGRPLAIAGNAKERKGIVVTCSYEARARGVKPPMPLWEAKRLCPELIVK
PPNFDRYRSSSREMFQVLREYTDLVEPVSIDEGYMDLTDTPYRNRACETAKEIQERLQKELLLPSSIGIAPNKFLAKMAS
DMKKPLGITILRKREVPRILWPMDISEMYGVGRKTAEKLKTLEIEKIGDLAAADEYALKRLLGINGPRLKRRANGIDTGE
VNPDRIYEFKSVGNSSTLPHDSTDEKELFGLIDKLSISVSDRLKRKEVMAAKVFIMIRFADWTNITRSKTLLNPTDSKDE
IAKESKALFRQHWHGSPVRLLGVTGTDLVNRKEAVKQLDLFSFHEDAKDEPIQKVMAELNEKYGTDLIKKGVRIVKKESK
TSGTSFNKDFFQDERQDQ
>Mature_417_residues
SADKQKGRVIFHIDMNSFYASVEMAYDPSLKGRPLAIAGNAKERKGIVVTCSYEARARGVKPPMPLWEAKRLCPELIVKP
PNFDRYRSSSREMFQVLREYTDLVEPVSIDEGYMDLTDTPYRNRACETAKEIQERLQKELLLPSSIGIAPNKFLAKMASD
MKKPLGITILRKREVPRILWPMDISEMYGVGRKTAEKLKTLEIEKIGDLAAADEYALKRLLGINGPRLKRRANGIDTGEV
NPDRIYEFKSVGNSSTLPHDSTDEKELFGLIDKLSISVSDRLKRKEVMAAKVFIMIRFADWTNITRSKTLLNPTDSKDEI
AKESKALFRQHWHGSPVRLLGVTGTDLVNRKEAVKQLDLFSFHEDAKDEPIQKVMAELNEKYGTDLIKKGVRIVKKESKT
SGTSFNKDFFQDERQDQ

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI154350220, Length=271, Percent_Identity=32.1033210332103, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI84043967, Length=389, Percent_Identity=26.2210796915167, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI7706681, Length=390, Percent_Identity=26.1538461538462, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI7705344, Length=111, Percent_Identity=43.2432432432432, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI5729982, Length=154, Percent_Identity=32.4675324675325, Blast_Score=85, Evalue=1e-16,
Organism=Escherichia coli, GI1786425, Length=343, Percent_Identity=34.6938775510204, Blast_Score=200, Evalue=2e-52,
Organism=Escherichia coli, GI1787432, Length=391, Percent_Identity=26.3427109974425, Blast_Score=99, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI193205700, Length=411, Percent_Identity=25.3041362530414, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17537959, Length=260, Percent_Identity=27.3076923076923, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI115534089, Length=160, Percent_Identity=35, Blast_Score=85, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI193205702, Length=347, Percent_Identity=23.342939481268, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6324921, Length=211, Percent_Identity=27.9620853080569, Blast_Score=79, Evalue=9e-16,
Organism=Drosophila melanogaster, GI21355641, Length=274, Percent_Identity=32.1167883211679, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24644984, Length=274, Percent_Identity=32.1167883211679, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI19923006, Length=345, Percent_Identity=26.9565217391304, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24668444, Length=119, Percent_Identity=37.8151260504202, Blast_Score=89, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 47606; Mature: 47475

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSADKQKGRVIFHIDMNSFYASVEMAYDPSLKGRPLAIAGNAKERKGIVVTCSYEARARG
CCCCCCCCCEEEEEECCCCEEEEEEEECCCCCCCCEEEECCCCCCCCEEEEEECHHHHCC
VKPPMPLWEAKRLCPELIVKPPNFDRYRSSSREMFQVLREYTDLVEPVSIDEGYMDLTDT
CCCCCCHHHHHHHHHHHCCCCCCCHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
PYRNRACETAKEIQERLQKELLLPSSIGIAPNKFLAKMASDMKKPLGITILRKREVPRIL
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCEE
WPMDISEMYGVGRKTAEKLKTLEIEKIGDLAAADEYALKRLLGINGPRLKRRANGIDTGE
CCCCHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCC
VNPDRIYEFKSVGNSSTLPHDSTDEKELFGLIDKLSISVSDRLKRKEVMAAKVFIMIRFA
CCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEC
DWTNITRSKTLLNPTDSKDEIAKESKALFRQHWHGSPVRLLGVTGTDLVNRKEAVKQLDL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHH
FSFHEDAKDEPIQKVMAELNEKYGTDLIKKGVRIVKKESKTSGTSFNKDFFQDERQDQ
HHHCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCC
>Mature Secondary Structure 
SADKQKGRVIFHIDMNSFYASVEMAYDPSLKGRPLAIAGNAKERKGIVVTCSYEARARG
CCCCCCCCEEEEEECCCCEEEEEEEECCCCCCCCEEEECCCCCCCCEEEEEECHHHHCC
VKPPMPLWEAKRLCPELIVKPPNFDRYRSSSREMFQVLREYTDLVEPVSIDEGYMDLTDT
CCCCCCHHHHHHHHHHHCCCCCCCHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
PYRNRACETAKEIQERLQKELLLPSSIGIAPNKFLAKMASDMKKPLGITILRKREVPRIL
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCEE
WPMDISEMYGVGRKTAEKLKTLEIEKIGDLAAADEYALKRLLGINGPRLKRRANGIDTGE
CCCCHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCC
VNPDRIYEFKSVGNSSTLPHDSTDEKELFGLIDKLSISVSDRLKRKEVMAAKVFIMIRFA
CCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEC
DWTNITRSKTLLNPTDSKDEIAKESKALFRQHWHGSPVRLLGVTGTDLVNRKEAVKQLDL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHH
FSFHEDAKDEPIQKVMAELNEKYGTDLIKKGVRIVKKESKTSGTSFNKDFFQDERQDQ
HHHCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]