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The map label for this gene is ydhP [H]

Identifier: 52786298

GI number: 52786298

Start: 2479373

End: 2480788

Strand: Reverse

Name: ydhP [H]

Synonym: BLi02560

Alternate gene names: 52786298

Gene position: 2480788-2479373 (Counterclockwise)

Preceding gene: 52786299

Following gene: 52786297

Centisome position: 58.75

GC content: 46.68

Gene sequence:

>1416_bases
ATGTCAAAAACAGAACCGCAGCTAGAACAAATTCAATACCGTTTTCCAAATGGCTTCTGGTGGGGGTCGGCGGCTTCCGC
CACTCAGACTGAAGGAGCGGCGGCCGAAGGAGGCAAAGGAAAGAACATTTGGGATCACTGGTACGAAAAAGAGCCAAACC
GATTTTTTGACGGAGTAGGCCCTGAGAAGACTTCGCGTTTTTACGAGACTTACAGAGAAGATATTCAGCTGATGAAAGAG
CTTGGCCACCACTCTTTTCGTTTCTCCATTTCGTGGGCTCGTCTGTTTCCTGATGGAAAAGGGCGGCTGAACAAAGAAGG
AGCTGCCTTTTATAACCGAGTCATCGATGAACTGCTTGCGGCTGGCATCGAGCCTTTTGTCAACCTTTATCATTTTGACA
TGCCGCTTGCGCTCCAGCAAATCGGCGGATGGGAAAACAGGCAAGTCGTCGATCACTTTGCTTCATACGCGGAAACGTGC
TTCAGGCTGTACGGGGACCGAGTGAAAAAATGGTTTACCCACAATGAGCCGATCGTTCCTGCAGAAGGCGGCTATCTATA
CGATTTTCACTATCCGAACATCGTCGACTTTCAAAAAGCCGTCCAGGTCGCATACCATGAAATTCTTTCAAACGCTAAAG
CTGTCGAAGCTTATCGCAGACTCGGGGGCGACGGCAAAATCGGCATCATTTTAAATTTAACGCCGTCCTACCCGCGAAGC
CAGCATCCGGCAGATGTAAGAGCATCTGAAATAGCCGACGCTTTCTTTAACCGATCGTTTCTTGATCCCGCCGTTAAGGG
TGAGTTTCCGCAGCTTTTAACAGATATATTAAAAGAAGAAGGCTATTTGCCTGTCATGGAAGAAGGAGACTTGGAGCTGA
TCAAAAATCACACTGTCGATCTGCTCGGCATCAATTATTATCAGCCGAGACGGGTGAAAGCGAAGGAGCACCTGCCTCAT
CCGGACGCGCCTTTTATGCCGGAACGGTTTTTTGACCATTATGAAATGCCCGGACGAAAAATGAACCGCCACCGCGGCTG
GGAGATATATGAAAAAGGAATCTATGATATTTTAATCAATGTCAAAGAAAACTACGGAAATATTGAATGCTTTATTTCTG
AAAATGGGATGGGCGTTGAAGGAGAAGAACGTTTCCGCGGCGAAGACGGCATGATCCGCGATGACTACAGAATTTCGTTT
ATAAAAGAACACTTAAAATGGGTGCACAGAGCCATTCAGGAAGGAGCGAATGTCAAAGGCTATCATCTTTGGACCTTCAT
GGACAACTGGTCATGGACGAACGCCTATAAAAACCGCTACGGTTTTGTATCTGTCAACCTTGACAAAAACGGCGAACGAA
CGATTAAAAAAAGCGGATACTGGTTTAAGAAAGTTGCCGAGAACAACGGTTTTTAA

Upstream 100 bases:

>100_bases
TTTGAAATTCATCGACCGGATGAATATGAAAAAAGAGCAGGAGATCAATGAAGCGGAACAAGAAAAGACAACACTAGGAC
TTTAAAAGGAGATTGATGAC

Downstream 100 bases:

>100_bases
AAAGGGACTCGGGCTAAAAGATGGTCAGTTGGGCCATCTTTTTATTTCCGCATTAAAACCGATATAATGATAAAGAAGGT
GTTACAGGCTACAGAATCCT

Product: YdhP

Products: NA

Alternate protein names: Aryl-phospho-beta-D-glucosidase BglD; Glucomannan utilization protein D [H]

Number of amino acids: Translated: 471; Mature: 470

Protein sequence:

>471_residues
MSKTEPQLEQIQYRFPNGFWWGSAASATQTEGAAAEGGKGKNIWDHWYEKEPNRFFDGVGPEKTSRFYETYREDIQLMKE
LGHHSFRFSISWARLFPDGKGRLNKEGAAFYNRVIDELLAAGIEPFVNLYHFDMPLALQQIGGWENRQVVDHFASYAETC
FRLYGDRVKKWFTHNEPIVPAEGGYLYDFHYPNIVDFQKAVQVAYHEILSNAKAVEAYRRLGGDGKIGIILNLTPSYPRS
QHPADVRASEIADAFFNRSFLDPAVKGEFPQLLTDILKEEGYLPVMEEGDLELIKNHTVDLLGINYYQPRRVKAKEHLPH
PDAPFMPERFFDHYEMPGRKMNRHRGWEIYEKGIYDILINVKENYGNIECFISENGMGVEGEERFRGEDGMIRDDYRISF
IKEHLKWVHRAIQEGANVKGYHLWTFMDNWSWTNAYKNRYGFVSVNLDKNGERTIKKSGYWFKKVAENNGF

Sequences:

>Translated_471_residues
MSKTEPQLEQIQYRFPNGFWWGSAASATQTEGAAAEGGKGKNIWDHWYEKEPNRFFDGVGPEKTSRFYETYREDIQLMKE
LGHHSFRFSISWARLFPDGKGRLNKEGAAFYNRVIDELLAAGIEPFVNLYHFDMPLALQQIGGWENRQVVDHFASYAETC
FRLYGDRVKKWFTHNEPIVPAEGGYLYDFHYPNIVDFQKAVQVAYHEILSNAKAVEAYRRLGGDGKIGIILNLTPSYPRS
QHPADVRASEIADAFFNRSFLDPAVKGEFPQLLTDILKEEGYLPVMEEGDLELIKNHTVDLLGINYYQPRRVKAKEHLPH
PDAPFMPERFFDHYEMPGRKMNRHRGWEIYEKGIYDILINVKENYGNIECFISENGMGVEGEERFRGEDGMIRDDYRISF
IKEHLKWVHRAIQEGANVKGYHLWTFMDNWSWTNAYKNRYGFVSVNLDKNGERTIKKSGYWFKKVAENNGF
>Mature_470_residues
SKTEPQLEQIQYRFPNGFWWGSAASATQTEGAAAEGGKGKNIWDHWYEKEPNRFFDGVGPEKTSRFYETYREDIQLMKEL
GHHSFRFSISWARLFPDGKGRLNKEGAAFYNRVIDELLAAGIEPFVNLYHFDMPLALQQIGGWENRQVVDHFASYAETCF
RLYGDRVKKWFTHNEPIVPAEGGYLYDFHYPNIVDFQKAVQVAYHEILSNAKAVEAYRRLGGDGKIGIILNLTPSYPRSQ
HPADVRASEIADAFFNRSFLDPAVKGEFPQLLTDILKEEGYLPVMEEGDLELIKNHTVDLLGINYYQPRRVKAKEHLPHP
DAPFMPERFFDHYEMPGRKMNRHRGWEIYEKGIYDILINVKENYGNIECFISENGMGVEGEERFRGEDGMIRDDYRISFI
KEHLKWVHRAIQEGANVKGYHLWTFMDNWSWTNAYKNRYGFVSVNLDKNGERTIKKSGYWFKKVAENNGF

Specific function: Phospho-beta-D-glucosidase that seems to be involved in the degradation of glucomannan. Is also capable of hydrolyzing aryl-phospho-beta-D-glucosides, although very weakly, and plays only a minor role, if any, in the degradation of these substrates in viv

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI110681710, Length=479, Percent_Identity=32.776617954071, Blast_Score=230, Evalue=2e-60,
Organism=Homo sapiens, GI32481206, Length=500, Percent_Identity=31.6, Blast_Score=218, Evalue=1e-56,
Organism=Homo sapiens, GI13273313, Length=484, Percent_Identity=29.3388429752066, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI28376633, Length=467, Percent_Identity=29.7644539614561, Blast_Score=169, Evalue=5e-42,
Organism=Homo sapiens, GI24497614, Length=486, Percent_Identity=28.8065843621399, Blast_Score=167, Evalue=3e-41,
Organism=Homo sapiens, GI190360571, Length=107, Percent_Identity=33.6448598130841, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI2367174, Length=491, Percent_Identity=34.4195519348269, Blast_Score=239, Evalue=3e-64,
Organism=Escherichia coli, GI1789070, Length=481, Percent_Identity=35.1351351351351, Blast_Score=229, Evalue=3e-61,
Organism=Escherichia coli, GI2367270, Length=477, Percent_Identity=33.1236897274633, Blast_Score=217, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI17539390, Length=468, Percent_Identity=33.974358974359, Blast_Score=232, Evalue=3e-61,
Organism=Caenorhabditis elegans, GI17552856, Length=473, Percent_Identity=33.4038054968288, Blast_Score=230, Evalue=9e-61,
Organism=Drosophila melanogaster, GI21356577, Length=482, Percent_Identity=30.2904564315353, Blast_Score=216, Evalue=3e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 54900; Mature: 54769

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTEPQLEQIQYRFPNGFWWGSAASATQTEGAAAEGGKGKNIWDHWYEKEPNRFFDGVG
CCCCCCCHHHHHEECCCCEECCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCHHHCCCC
PEKTSRFYETYREDIQLMKELGHHSFRFSISWARLFPDGKGRLNKEGAAFYNRVIDELLA
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHEECCCCCCCCCCCHHHHHHHHHHHHHH
AGIEPFVNLYHFDMPLALQQIGGWENRQVVDHFASYAETCFRLYGDRVKKWFTHNEPIVP
HCHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
AEGGYLYDFHYPNIVDFQKAVQVAYHEILSNAKAVEAYRRLGGDGKIGIILNLTPSYPRS
CCCCEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEEEEECCCCCCC
QHPADVRASEIADAFFNRSFLDPAVKGEFPQLLTDILKEEGYLPVMEEGDLELIKNHTVD
CCCCCCHHHHHHHHHHCHHHCCHHHCCCHHHHHHHHHHCCCCCCEECCCCHHHHHCCCEE
LLGINYYQPRRVKAKEHLPHPDAPFMPERFFDHYEMPGRKMNRHRGWEIYEKGIYDILIN
EEECCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHCCCCHHHHHCCCHHHHHCCCEEEEEE
VKENYGNIECFISENGMGVEGEERFRGEDGMIRDDYRISFIKEHLKWVHRAIQEGANVKG
EECCCCCEEEEECCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCE
YHLWTFMDNWSWTNAYKNRYGFVSVNLDKNGERTIKKSGYWFKKVAENNGF
EEEEEEECCCCHHHHHHCCCEEEEEEECCCCCHHHHHCCCHHHHHHCCCCC
>Mature Secondary Structure 
SKTEPQLEQIQYRFPNGFWWGSAASATQTEGAAAEGGKGKNIWDHWYEKEPNRFFDGVG
CCCCCCHHHHHEECCCCEECCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCHHHCCCC
PEKTSRFYETYREDIQLMKELGHHSFRFSISWARLFPDGKGRLNKEGAAFYNRVIDELLA
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHEECCCCCCCCCCCHHHHHHHHHHHHHH
AGIEPFVNLYHFDMPLALQQIGGWENRQVVDHFASYAETCFRLYGDRVKKWFTHNEPIVP
HCHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
AEGGYLYDFHYPNIVDFQKAVQVAYHEILSNAKAVEAYRRLGGDGKIGIILNLTPSYPRS
CCCCEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEEEEECCCCCCC
QHPADVRASEIADAFFNRSFLDPAVKGEFPQLLTDILKEEGYLPVMEEGDLELIKNHTVD
CCCCCCHHHHHHHHHHCHHHCCHHHCCCHHHHHHHHHHCCCCCCEECCCCHHHHHCCCEE
LLGINYYQPRRVKAKEHLPHPDAPFMPERFFDHYEMPGRKMNRHRGWEIYEKGIYDILIN
EEECCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHCCCCHHHHHCCCHHHHHCCCEEEEEE
VKENYGNIECFISENGMGVEGEERFRGEDGMIRDDYRISFIKEHLKWVHRAIQEGANVKG
EECCCCCEEEEECCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCE
YHLWTFMDNWSWTNAYKNRYGFVSVNLDKNGERTIKKSGYWFKKVAENNGF
EEEEEEECCCCHHHHHHCCCEEEEEEECCCCCHHHHHCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9202461; 9384377 [H]