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The map label for this gene is yqjK

Identifier: 52786292

GI number: 52786292

Start: 2472071

End: 2472994

Strand: Reverse

Name: yqjK

Synonym: BLi02554

Alternate gene names: 52786292

Gene position: 2472994-2472071 (Counterclockwise)

Preceding gene: 52786294

Following gene: 52786291

Centisome position: 58.57

GC content: 49.46

Gene sequence:

>924_bases
TTGGAGTTATTATTTTTAGGAACGGGAGCGGGCATCCCCGCAAAAACGAGGAATGTCACATCCGTTGCATTGAAGCTTTT
AGAAGAAAGGCGGTCTGTTTGGCTGTTTGACTGCGGGGAAGCCACACAGCATCAAATTCTACATACATCGATCAAACCTA
GAAAAATTGAAAAGATTTTTATTACCCATCTTCACGGCGATCATGTATACGGGCTTCCGGGTCTTGTCAGCAGCCGATCT
TTCCAGGGAGGGGAAGGCCCGCTGACCGTATACGGACCGCAAGGAATCAAAACGTTTCTTGAAACGGCGCTTGACGTATC
GGGGACGCATGTCACATATCCGCTTGTGATTAAGGAGATTGGAGAAGGGACAGTCTTTGAGGATGACCAGTTTATCGTGA
CGGCCAGAAGCGTATCTCACGGCATTCCCGCTTTTGGGTACCGCGTGCAGGAAAAAGATGTTCCGGGCGCCCTTGACGCT
GAAGCACTGAAAGAGATCGGAGTCTCGCCGGGCCCTGTTTATCAAAAACTGAAAAACGGGGAGACGGTCACATTGGAAGA
CGGCCGGACGATTCATGGGGCAGACTTTATCGGACCGCCAAAAAAAGGGCGGATTGTCGCCTTTTCCGGGGATACGAGGC
CATGCGAGAATGTGAAGAGGCTTGCCGAAAAAGCCGATGTTCTCATCCACGAAGCAACATTTGCGAAAGGCGACAGGGAG
CTCGCCGGAGACTATTATCACAGCACTTCAGAACAAGCTGCTGAAACAGCGCGGGAAGCCTGTGCAAAAAAACTGATTTT
AACCCATATCAGTGCAAGATACCAGGGGGAAAACGTGCTTGAACTGGTCGATGAAGCAAAAGCGATCTTTCCTGATACCG
TGGCAGCTTTTGACTTTTATGAGCATGAGATCAAAAGAACTTAA

Upstream 100 bases:

>100_bases
GGTATTTAGTTGCATAGCCCGACGCGAGGCCGGCGTTTCTTTTTTCCAAGACTTCCTGTATGCTTGTGATAGATGAAGTT
TTTAGCAGGAGGAAAGGATA

Downstream 100 bases:

>100_bases
TGGGCAGTTATAAAGCTTCTTTGTTCCGACAATCCGGGACGGGAAGCTTTTTTTGTTGACACGGTTCTAAAATGATGTAT
AATAAAGCGTAATGATTACG

Product: ribonuclease Z

Products: NA

Alternate protein names: RNase Z; tRNA 3 endonuclease; tRNase Z

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MELLFLGTGAGIPAKTRNVTSVALKLLEERRSVWLFDCGEATQHQILHTSIKPRKIEKIFITHLHGDHVYGLPGLVSSRS
FQGGEGPLTVYGPQGIKTFLETALDVSGTHVTYPLVIKEIGEGTVFEDDQFIVTARSVSHGIPAFGYRVQEKDVPGALDA
EALKEIGVSPGPVYQKLKNGETVTLEDGRTIHGADFIGPPKKGRIVAFSGDTRPCENVKRLAEKADVLIHEATFAKGDRE
LAGDYYHSTSEQAAETAREACAKKLILTHISARYQGENVLELVDEAKAIFPDTVAAFDFYEHEIKRT

Sequences:

>Translated_307_residues
MELLFLGTGAGIPAKTRNVTSVALKLLEERRSVWLFDCGEATQHQILHTSIKPRKIEKIFITHLHGDHVYGLPGLVSSRS
FQGGEGPLTVYGPQGIKTFLETALDVSGTHVTYPLVIKEIGEGTVFEDDQFIVTARSVSHGIPAFGYRVQEKDVPGALDA
EALKEIGVSPGPVYQKLKNGETVTLEDGRTIHGADFIGPPKKGRIVAFSGDTRPCENVKRLAEKADVLIHEATFAKGDRE
LAGDYYHSTSEQAAETAREACAKKLILTHISARYQGENVLELVDEAKAIFPDTVAAFDFYEHEIKRT
>Mature_307_residues
MELLFLGTGAGIPAKTRNVTSVALKLLEERRSVWLFDCGEATQHQILHTSIKPRKIEKIFITHLHGDHVYGLPGLVSSRS
FQGGEGPLTVYGPQGIKTFLETALDVSGTHVTYPLVIKEIGEGTVFEDDQFIVTARSVSHGIPAFGYRVQEKDVPGALDA
EALKEIGVSPGPVYQKLKNGETVTLEDGRTIHGADFIGPPKKGRIVAFSGDTRPCENVKRLAEKADVLIHEATFAKGDRE
LAGDYYHSTSEQAAETAREACAKKLILTHISARYQGENVLELVDEAKAIFPDTVAAFDFYEHEIKRT

Specific function: Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA

COG id: COG1234

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily III

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase Z family

Homologues:

Organism=Homo sapiens, GI8922122, Length=323, Percent_Identity=38.390092879257, Blast_Score=218, Evalue=7e-57,
Organism=Escherichia coli, GI87082078, Length=300, Percent_Identity=52.6666666666667, Blast_Score=324, Evalue=3e-90,
Organism=Caenorhabditis elegans, GI71985808, Length=288, Percent_Identity=30.9027777777778, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71985814, Length=288, Percent_Identity=30.9027777777778, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24652403, Length=284, Percent_Identity=29.5774647887324, Blast_Score=97, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNZ_BACLD (Q65HN6)

Other databases:

- EMBL:   AE017333
- EMBL:   CP000002
- RefSeq:   YP_079708.1
- RefSeq:   YP_092121.1
- ProteinModelPortal:   Q65HN6
- SMR:   Q65HN6
- STRING:   Q65HN6
- EnsemblBacteria:   EBBACT00000055378
- EnsemblBacteria:   EBBACT00000061601
- GeneID:   3028024
- GeneID:   3100274
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi02554
- KEGG:   bli:BL05258
- NMPDR:   fig|279010.5.peg.399
- eggNOG:   COG1234
- GeneTree:   EBGT00050000001790
- HOGENOM:   HBG648406
- OMA:   HSTSTMA
- ProtClustDB:   PRK00055
- BioCyc:   BLIC279010-1:BLI02554-MONOMER
- BioCyc:   BLIC279010:BL05258-MONOMER
- HAMAP:   MF_01818
- InterPro:   IPR001279
- InterPro:   IPR013471
- SMART:   SM00849
- TIGRFAMs:   TIGR02651

Pfam domain/function: PF00753 Lactamase_B

EC number: =3.1.26.11

Molecular weight: Translated: 33627; Mature: 33627

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELLFLGTGAGIPAKTRNVTSVALKLLEERRSVWLFDCGEATQHQILHTSIKPRKIEKIF
CEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHCCCCCCEEEEEE
ITHLHGDHVYGLPGLVSSRSFQGGEGPLTVYGPQGIKTFLETALDVSGTHVTYPLVIKEI
EEEECCCEEECCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHCCCCCEEEHHHHHHHC
GEGTVFEDDQFIVTARSVSHGIPAFGYRVQEKDVPGALDAEALKEIGVSPGPVYQKLKNG
CCCCEEECCCEEEEECCCCCCCCCCCEEEECCCCCCCCCHHHHHHCCCCCCHHHHHHCCC
ETVTLEDGRTIHGADFIGPPKKGRIVAFSGDTRPCENVKRLAEKADVLIHEATFAKGDRE
CEEEECCCCEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHEEEEEHHHCCCCHH
LAGDYYHSTSEQAAETAREACAKKLILTHISARYQGENVLELVDEAKAIFPDTVAAFDFY
HCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHH
EHEIKRT
HHHHCCC
>Mature Secondary Structure
MELLFLGTGAGIPAKTRNVTSVALKLLEERRSVWLFDCGEATQHQILHTSIKPRKIEKIF
CEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHCCCCCCEEEEEE
ITHLHGDHVYGLPGLVSSRSFQGGEGPLTVYGPQGIKTFLETALDVSGTHVTYPLVIKEI
EEEECCCEEECCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHCCCCCEEEHHHHHHHC
GEGTVFEDDQFIVTARSVSHGIPAFGYRVQEKDVPGALDAEALKEIGVSPGPVYQKLKNG
CCCCEEECCCEEEEECCCCCCCCCCCEEEECCCCCCCCCHHHHHHCCCCCCHHHHHHCCC
ETVTLEDGRTIHGADFIGPPKKGRIVAFSGDTRPCENVKRLAEKADVLIHEATFAKGDRE
CEEEECCCCEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHEEEEEHHHCCCCHH
LAGDYYHSTSEQAAETAREACAKKLILTHISARYQGENVLELVDEAKAIFPDTVAAFDFY
HCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHH
EHEIKRT
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA