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The map label for this gene is ribD [H]

Identifier: 52786214

GI number: 52786214

Start: 2407921

End: 2409009

Strand: Reverse

Name: ribD [H]

Synonym: BLi02475

Alternate gene names: 52786214

Gene position: 2409009-2407921 (Counterclockwise)

Preceding gene: 52786215

Following gene: 52786213

Centisome position: 57.05

GC content: 52.53

Gene sequence:

>1089_bases
ATGACGGATGCGCATTATATGAATCTTGCATTGGAGCTGGCGAGGCAGGGCGAAGGCCAGACCGGGGCCAATCCGCTTGT
CGGAGCGGTTGTCGTCAAAGACGGCGAAGTGGTCGGAATGGGAGCCCATTTAAAATACGGCGAAGCACATGCAGAAGTGC
ACGCCATTCAAATGGCAGGCCGCCATGCGGAAGGAGCCGTCATCTATGTGACGCTTGAACCGTGCAGCCATTACGGCAAA
ACGCCTCCTTGCGCGGAACTGATTATTCGTTCCGGTTTGAAGCGGGTGGTCGTGGCTGCGGAAGATCCGAATCCGCTCGT
TTCCGGAAGAGGAATCGAGATGCTGAGAAGCGCCGGGATCGAGGTGGAAACAGGCGTTCTCAAAGAACAGGCGGAAGAGC
TGAATGAAAAGTTCATGCATTTTATGCGGACAGGCCTTCCGTATGTGACATTAAAAGCCGCTGCAAGCCTTGACGGCAAA
ACCGCCACCGCAACAGGCGACAGCAAATGGATTACTTCTGAAGAAGCGCGGATGGATGCTCACCAATACCGAAAAAACCA
CCAGTGTATTTTAGTCGGATCGGGCACAATAAAAGCAGACGACCCAAGTTTGACATGCCGTCTCCCCGGTGCGGTGAATC
AGCCGGTGCGCGTCGTTCTCGATACGACGCTGTCAATCCCGCTCCAGTCAAAAGTGATTCAGGATAAAGAAGCGCCTACT
TGGATTTACACGACGTCCAAGGCAGATCCCGAAAAGGTTCGGAACGTGGAAAAAGAAGGTGTGCAGGTAACCGTGCTCGA
TGCGGATGAACTTCAGGTGCGCGACGTGCTTCTGCACCTTGCAGACCGCGGCATCGCTTCAGTCTTTGTCGAAGGAGGCG
CAACGGTTCACGCAAGCTTCGTCAAAGAAGGACTCTATCAGCAAATAATCTTCTATCTTGCCCCTAAATTAATCGGAGGG
CTGCAATCTCCCAGCATCCTCTCCGGTGAAGGCTTTCAATCGATGAAAGATGTCCCCTTACTGCAATTCACAACCATTAC
CAAGATCGGCCAGGATATAAAGCTGGCAGCAAGACCGATAAAAGAATAA

Upstream 100 bases:

>100_bases
GTAAAAAATAATGAATAAGCATAGTTTTATTTCTCATGCACAAAAACAACCCCCGGATCAACATCCGGGGTTATTTTTTT
GAAAGAAGGGAGGGAAATTC

Downstream 100 bases:

>100_bases
GGCGGTGACATATGTTTACAGGCATCATTGAAGAAGTCGGAACGATTTTGGACATGAAAAAGGCGGGAAGCGCCATGTCT
TTAGTCATTCAATCCAACAA

Product: hypothetical protein

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MTDAHYMNLALELARQGEGQTGANPLVGAVVVKDGEVVGMGAHLKYGEAHAEVHAIQMAGRHAEGAVIYVTLEPCSHYGK
TPPCAELIIRSGLKRVVVAAEDPNPLVSGRGIEMLRSAGIEVETGVLKEQAEELNEKFMHFMRTGLPYVTLKAAASLDGK
TATATGDSKWITSEEARMDAHQYRKNHQCILVGSGTIKADDPSLTCRLPGAVNQPVRVVLDTTLSIPLQSKVIQDKEAPT
WIYTTSKADPEKVRNVEKEGVQVTVLDADELQVRDVLLHLADRGIASVFVEGGATVHASFVKEGLYQQIIFYLAPKLIGG
LQSPSILSGEGFQSMKDVPLLQFTTITKIGQDIKLAARPIKE

Sequences:

>Translated_362_residues
MTDAHYMNLALELARQGEGQTGANPLVGAVVVKDGEVVGMGAHLKYGEAHAEVHAIQMAGRHAEGAVIYVTLEPCSHYGK
TPPCAELIIRSGLKRVVVAAEDPNPLVSGRGIEMLRSAGIEVETGVLKEQAEELNEKFMHFMRTGLPYVTLKAAASLDGK
TATATGDSKWITSEEARMDAHQYRKNHQCILVGSGTIKADDPSLTCRLPGAVNQPVRVVLDTTLSIPLQSKVIQDKEAPT
WIYTTSKADPEKVRNVEKEGVQVTVLDADELQVRDVLLHLADRGIASVFVEGGATVHASFVKEGLYQQIIFYLAPKLIGG
LQSPSILSGEGFQSMKDVPLLQFTTITKIGQDIKLAARPIKE
>Mature_361_residues
TDAHYMNLALELARQGEGQTGANPLVGAVVVKDGEVVGMGAHLKYGEAHAEVHAIQMAGRHAEGAVIYVTLEPCSHYGKT
PPCAELIIRSGLKRVVVAAEDPNPLVSGRGIEMLRSAGIEVETGVLKEQAEELNEKFMHFMRTGLPYVTLKAAASLDGKT
ATATGDSKWITSEEARMDAHQYRKNHQCILVGSGTIKADDPSLTCRLPGAVNQPVRVVLDTTLSIPLQSKVIQDKEAPTW
IYTTSKADPEKVRNVEKEGVQVTVLDADELQVRDVLLHLADRGIASVFVEGGATVHASFVKEGLYQQIIFYLAPKLIGGL
QSPSILSGEGFQSMKDVPLLQFTTITKIGQDIKLAARPIKE

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=373, Percent_Identity=41.2868632707775, Blast_Score=290, Evalue=1e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 39096; Mature: 38965

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDAHYMNLALELARQGEGQTGANPLVGAVVVKDGEVVGMGAHLKYGEAHAEVHAIQMAG
CCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCEEEECCCEECCCHHHHEEEEEECC
RHAEGAVIYVTLEPCSHYGKTPPCAELIIRSGLKRVVVAAEDPNPLVSGRGIEMLRSAGI
CCCCCEEEEEEECCHHCCCCCCCHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHCCC
EVETGVLKEQAEELNEKFMHFMRTGLPYVTLKAAASLDGKTATATGDSKWITSEEARMDA
EEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHCCCCCEEECCCCCCEECCHHHHHHH
HQYRKNHQCILVGSGTIKADDPSLTCRLPGAVNQPVRVVLDTTLSIPLQSKVIQDKEAPT
HHHHCCCCEEEEECCEEEECCCCEEEECCCCCCCCEEEEEECCCCCCHHHHHHCCCCCCE
WIYTTSKADPEKVRNVEKEGVQVTVLDADELQVRDVLLHLADRGIASVFVEGGATVHASF
EEEECCCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCEEEHHH
VKEGLYQQIIFYLAPKLIGGLQSPSILSGEGFQSMKDVPLLQFTTITKIGQDIKLAARPI
HHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCHHHCCCEEEEHHHHHCCCCCEECCCCC
KE
CC
>Mature Secondary Structure 
TDAHYMNLALELARQGEGQTGANPLVGAVVVKDGEVVGMGAHLKYGEAHAEVHAIQMAG
CCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCEEEECCCEECCCHHHHEEEEEECC
RHAEGAVIYVTLEPCSHYGKTPPCAELIIRSGLKRVVVAAEDPNPLVSGRGIEMLRSAGI
CCCCCEEEEEEECCHHCCCCCCCHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHCCC
EVETGVLKEQAEELNEKFMHFMRTGLPYVTLKAAASLDGKTATATGDSKWITSEEARMDA
EEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHCCCCCEEECCCCCCEECCHHHHHHH
HQYRKNHQCILVGSGTIKADDPSLTCRLPGAVNQPVRVVLDTTLSIPLQSKVIQDKEAPT
HHHHCCCCEEEEECCEEEECCCCEEEECCCCCCCCEEEEEECCCCCCHHHHHHCCCCCCE
WIYTTSKADPEKVRNVEKEGVQVTVLDADELQVRDVLLHLADRGIASVFVEGGATVHASF
EEEECCCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCEEEHHH
VKEGLYQQIIFYLAPKLIGGLQSPSILSGEGFQSMKDVPLLQFTTITKIGQDIKLAARPI
HHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCHHHCCCEEEEHHHHHCCCCCEECCCCC
KE
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 2112225; 9068650 [H]