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The map label for this gene is cmk

Identifier: 52786170

GI number: 52786170

Start: 2366728

End: 2367408

Strand: Reverse

Name: cmk

Synonym: BLi02428

Alternate gene names: 52786170

Gene position: 2367408-2366728 (Counterclockwise)

Preceding gene: 52786171

Following gene: 52786169

Centisome position: 56.06

GC content: 49.19

Gene sequence:

>681_bases
ATGGAAAAGAAATTATGCATTGCAATAGACGGCCCTGCGGCAGCCGGAAAAAGCACCGTGGCGAAAATCGTGGCCAGAAA
AAAGTCGTATATTTATATTGATACGGGTGCCATGTACAGGGCGATTACGTATCTAGCGCTGGAAAAGGGCGTTGATTTAA
ACGACGAAGCGGCGCTGACGGCCTTGTTAAAAGAATCTGCCATCGATCTCACGGTTTCGCCTGAAGGAGAGCAGAAGGTT
TATATCGCAGGCGAAGATGTAACAGAGGCGATCCGCACGGATAGCGTGAGCAACCAAGTCTCCATCGTCGCCAAATACGC
CGGGATCCGCGAAGAAATGACGAAAAGGCAGCAGCAGCTGGCTGAAAAAGGCGGAGTCGTCATGGACGGCCGCGACATCG
GAACCCACGTTCTCCCGAATGCGGAAGTGAAAATATTTCTCTTGGCGTCCGTCGAGGAGCGGGCAAAACGCCGCTTTGAA
GAAAACGTCAAAAAAGGGTACAATGTAAATTATGAAACGCTTGCAGAAGAAATCAGGCGCCGTGACAAACTCGATTCAGA
GCGCGAGATTTCCCCGTTGAAAAAAGCGGACGATGCGCTTGAAATCGACACGACTTCATTGACGATCGATGAAGTGGCCG
AAAAAATTCTGCAGATTGTAGACAAAAAGGCTCAAAAATAA

Upstream 100 bases:

>100_bases
ATCGAGACATTTAAGCCGTAATTCACGCTAAAATCTCCCCTTTTTCGCCTAATACATGATACAATCCTATAAGGAGTACC
AGATAGCAAGGAGAGGAATT

Downstream 100 bases:

>100_bases
AAAATCCGGGCAAATTACTTATTGTCTGCATGTTTTGACTTGACAAACACAGGCTTTTATTAGAAGTTAGTAATAATAAA
TCATGTTTTAGAACATTCAA

Product: cytidylate kinase

Products: NA

Alternate protein names: CK; Cytidine monophosphate kinase; CMP kinase

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MEKKLCIAIDGPAAAGKSTVAKIVARKKSYIYIDTGAMYRAITYLALEKGVDLNDEAALTALLKESAIDLTVSPEGEQKV
YIAGEDVTEAIRTDSVSNQVSIVAKYAGIREEMTKRQQQLAEKGGVVMDGRDIGTHVLPNAEVKIFLLASVEERAKRRFE
ENVKKGYNVNYETLAEEIRRRDKLDSEREISPLKKADDALEIDTTSLTIDEVAEKILQIVDKKAQK

Sequences:

>Translated_226_residues
MEKKLCIAIDGPAAAGKSTVAKIVARKKSYIYIDTGAMYRAITYLALEKGVDLNDEAALTALLKESAIDLTVSPEGEQKV
YIAGEDVTEAIRTDSVSNQVSIVAKYAGIREEMTKRQQQLAEKGGVVMDGRDIGTHVLPNAEVKIFLLASVEERAKRRFE
ENVKKGYNVNYETLAEEIRRRDKLDSEREISPLKKADDALEIDTTSLTIDEVAEKILQIVDKKAQK
>Mature_226_residues
MEKKLCIAIDGPAAAGKSTVAKIVARKKSYIYIDTGAMYRAITYLALEKGVDLNDEAALTALLKESAIDLTVSPEGEQKV
YIAGEDVTEAIRTDSVSNQVSIVAKYAGIREEMTKRQQQLAEKGGVVMDGRDIGTHVLPNAEVKIFLLASVEERAKRRFE
ENVKKGYNVNYETLAEEIRRRDKLDSEREISPLKKADDALEIDTTSLTIDEVAEKILQIVDKKAQK

Specific function: ATP, Datp, And GTP Are Equally Effective As Phosphate Donors. CMP And Dcmp Are The Best Phosphate Acceptors. [C]

COG id: COG0283

COG function: function code F; Cytidylate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidylate kinase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1787139, Length=218, Percent_Identity=44.954128440367, Blast_Score=177, Evalue=6e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KCY_BACLD (Q65I08)

Other databases:

- EMBL:   CP000002
- EMBL:   AE017333
- RefSeq:   YP_079591.1
- RefSeq:   YP_091999.1
- HSSP:   Q97PK6
- ProteinModelPortal:   Q65I08
- SMR:   Q65I08
- STRING:   Q65I08
- EnsemblBacteria:   EBBACT00000055713
- EnsemblBacteria:   EBBACT00000060431
- GeneID:   3027364
- GeneID:   3097700
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi02428
- KEGG:   bli:BL02219
- NMPDR:   fig|279010.5.peg.294
- eggNOG:   COG0283
- GeneTree:   EBGT00050000002974
- HOGENOM:   HBG354377
- OMA:   DIGTVIC
- ProtClustDB:   PRK00023
- BioCyc:   BLIC279010-1:BLI02428-MONOMER
- BioCyc:   BLIC279010:BL02219-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00238
- InterPro:   IPR003136
- InterPro:   IPR011994
- PANTHER:   PTHR21299:SF2
- TIGRFAMs:   TIGR00017

Pfam domain/function: PF02224 Cytidylate_kin

EC number: =2.7.4.14

Molecular weight: Translated: 25048; Mature: 25048

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKKLCIAIDGPAAAGKSTVAKIVARKKSYIYIDTGAMYRAITYLALEKGVDLNDEAALT
CCCCEEEEECCCCCCCHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCCCCHHHHHH
ALLKESAIDLTVSPEGEQKVYIAGEDVTEAIRTDSVSNQVSIVAKYAGIREEMTKRQQQL
HHHHHHCEEEEECCCCCCEEEEECCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
AEKGGVVMDGRDIGTHVLPNAEVKIFLLASVEERAKRRFEENVKKGYNVNYETLAEEIRR
HHHCCEEEECCCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
RDKLDSEREISPLKKADDALEIDTTSLTIDEVAEKILQIVDKKAQK
HHCCCCCCCCCHHHHCCCCEEECCCEEEHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEKKLCIAIDGPAAAGKSTVAKIVARKKSYIYIDTGAMYRAITYLALEKGVDLNDEAALT
CCCCEEEEECCCCCCCHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCCCCHHHHHH
ALLKESAIDLTVSPEGEQKVYIAGEDVTEAIRTDSVSNQVSIVAKYAGIREEMTKRQQQL
HHHHHHCEEEEECCCCCCEEEEECCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
AEKGGVVMDGRDIGTHVLPNAEVKIFLLASVEERAKRRFEENVKKGYNVNYETLAEEIRR
HHHCCEEEECCCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
RDKLDSEREISPLKKADDALEIDTTSLTIDEVAEKILQIVDKKAQK
HHCCCCCCCCCHHHHCCCCEEECCCEEEHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA