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The map label for this gene is xpt

Identifier: 52786092

GI number: 52786092

Start: 2294986

End: 2295570

Strand: Reverse

Name: xpt

Synonym: BLi02348

Alternate gene names: 52786092

Gene position: 2295570-2294986 (Counterclockwise)

Preceding gene: 52786093

Following gene: 52786091

Centisome position: 54.36

GC content: 47.35

Gene sequence:

>585_bases
ATGGAAAAGCTAAAACGAAAAATTGCAGAGCAGGGCACGGTGTTGTCTGACGAAGTGCTGAAAGTTGATTCATTTTTAAA
TCATCAAATCGATCCGGAATTAATGCTTGCTGTGGGTGAAGAGTTTGCTTCGCTTTTCCGGGAGGAAGGCGTCACAAAGA
TTGTGACGATTGAATCCTCAGGCATCGCACCTGCCGTGATGGCCGGCTTGAAGCTGGGCGTGCCGGTAGTATTTGCAAGA
AAGCGTCAATCGCTTACCTTGACGGAAAATCTGTTGACGGCTTCTGTCTATTCATTTACAAAGAAAACGGAAAGTACGGT
TGCCGTATCAGCCAGCCACCTTTCAAAGGATGACAAAGTTCTGATCATCGACGATTTTTTGGCAAACGGACAAGCAGCTA
AAGGGCTCGTTTCCATCATTGAACAGGCCGGCGCTAAGGTGTGCGGAATCGGAATCGTCATCGAGAAATCATTCCAGACG
GGCAGGGAGGAACTTGAAAATCTTGGAATCAGAGTCGAATCCCTTGCGCGTATTGCCTCTCTTGCCGGTGGAAAAGTTAC
CTTTTTACAGGAGGTTGGGTCATGA

Upstream 100 bases:

>100_bases
CTGACGGAATTCGTCTTTTTAAGCATTGCCCGCTCGCATTTCAAATCCGAGCGGACAATGCTTTTTTTTATGAAGGGCAA
TTGATGAACGGAGGGGTTTA

Downstream 100 bases:

>100_bases
AACTTACAGCCGGTAAAACTGTTTCATTAAGCATTCAGCACGTCCTTGCCATGTATGCAGGAGCCGTTGTCGTACCGCTG
ATCGTCGGCGGCGCTCTCGG

Product: xanthine phosphoribosyltransferase

Products: NA

Alternate protein names: XPRTase

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MEKLKRKIAEQGTVLSDEVLKVDSFLNHQIDPELMLAVGEEFASLFREEGVTKIVTIESSGIAPAVMAGLKLGVPVVFAR
KRQSLTLTENLLTASVYSFTKKTESTVAVSASHLSKDDKVLIIDDFLANGQAAKGLVSIIEQAGAKVCGIGIVIEKSFQT
GREELENLGIRVESLARIASLAGGKVTFLQEVGS

Sequences:

>Translated_194_residues
MEKLKRKIAEQGTVLSDEVLKVDSFLNHQIDPELMLAVGEEFASLFREEGVTKIVTIESSGIAPAVMAGLKLGVPVVFAR
KRQSLTLTENLLTASVYSFTKKTESTVAVSASHLSKDDKVLIIDDFLANGQAAKGLVSIIEQAGAKVCGIGIVIEKSFQT
GREELENLGIRVESLARIASLAGGKVTFLQEVGS
>Mature_194_residues
MEKLKRKIAEQGTVLSDEVLKVDSFLNHQIDPELMLAVGEEFASLFREEGVTKIVTIESSGIAPAVMAGLKLGVPVVFAR
KRQSLTLTENLLTASVYSFTKKTESTVAVSASHLSKDDKVLIIDDFLANGQAAKGLVSIIEQAGAKVCGIGIVIEKSFQT
GREELENLGIRVESLARIASLAGGKVTFLQEVGS

Specific function: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XPT subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XPT_BACLD (Q65I86)

Other databases:

- EMBL:   CP000002
- EMBL:   AE017333
- RefSeq:   YP_079510.1
- RefSeq:   YP_091921.1
- HSSP:   P42085
- ProteinModelPortal:   Q65I86
- SMR:   Q65I86
- STRING:   Q65I86
- EnsemblBacteria:   EBBACT00000057102
- EnsemblBacteria:   EBBACT00000062612
- GeneID:   3029347
- GeneID:   3098615
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi02348
- KEGG:   bli:BL00680
- NMPDR:   fig|279010.5.peg.199
- eggNOG:   COG0503
- GeneTree:   EBGT00050000001498
- HOGENOM:   HBG288993
- OMA:   ATVYSFT
- ProtClustDB:   PRK09219
- BioCyc:   BLIC279010-1:BLI02348-MONOMER
- BioCyc:   BLIC279010:BL00680-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01184
- InterPro:   IPR000836
- InterPro:   IPR010079
- TIGRFAMs:   TIGR01744

Pfam domain/function: PF00156 Pribosyltran

EC number: =2.4.2.22

Molecular weight: Translated: 20761; Mature: 20761

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: BINDING 20-20 BINDING 27-27 BINDING 156-156

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKLKRKIAEQGTVLSDEVLKVDSFLNHQIDPELMLAVGEEFASLFREEGVTKIVTIESS
CHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECC
GIAPAVMAGLKLGVPVVFARKRQSLTLTENLLTASVYSFTKKTESTVAVSASHLSKDDKV
CCCHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEHHHCCCCCCE
LIIDDFLANGQAAKGLVSIIEQAGAKVCGIGIVIEKSFQTGREELENLGIRVESLARIAS
EEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEEEECCHHHHHHHHHHHCCCHHHHHHHHH
LAGGKVTFLQEVGS
HCCCCEEHHHHHCC
>Mature Secondary Structure
MEKLKRKIAEQGTVLSDEVLKVDSFLNHQIDPELMLAVGEEFASLFREEGVTKIVTIESS
CHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECC
GIAPAVMAGLKLGVPVVFARKRQSLTLTENLLTASVYSFTKKTESTVAVSASHLSKDDKV
CCCHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEHHHCCCCCCE
LIIDDFLANGQAAKGLVSIIEQAGAKVCGIGIVIEKSFQTGREELENLGIRVESLARIAS
EEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEEEECCHHHHHHHHHHHCCCHHHHHHHHH
LAGGKVTFLQEVGS
HCCCCEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA