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The map label for this gene is ccpA [H]

Identifier: 52785873

GI number: 52785873

Start: 2067841

End: 2068851

Strand: Direct

Name: ccpA [H]

Synonym: BLi02121

Alternate gene names: 52785873

Gene position: 2067841-2068851 (Clockwise)

Preceding gene: 52785862

Following gene: 52785878

Centisome position: 48.97

GC content: 40.55

Gene sequence:

>1011_bases
ATGACTGTAACCATTAAAGACATCGCCAATGCTTCCGGAGTAAGCTATTCAACAGTCTCAAAGGCTTTAAGAAACAGCCC
TCTTGTAAAACCGGATACAAAGAAAAAGGTCTTGCAAGTTGCCGAACAATTAGGGTATAGTCCGAATTTTGCAGCGAGAA
GCTTGGCATCTAAAAAAAGTCAAACGATCGGTCTTGTCTGGCCTACCATTGAAAGAATCGCTTTATCAGCACTTGTTACT
AAAATAAATGAAGTGGTCGAAAAGAACAACTATTCAATGATTTTATCTGTTAACAGAGCTAAAGAGGCAGTGGATTTGTT
TAAGAGTTTTCGCGTGGATGGAATTATGATTTTTGAAGAAGGCGGCGAAACTCAGCTTAGTGATGATACTGGCTTAACTA
TTCCTATCTTATCTTACGGAGTGTCAGGTGAACATACACATCCTATTATCGATGTCAATCATAAAAAAGCAATTTACAAA
GCCGTTGCGTATCTGTATCAACTTGGCCACAAAAACATTAGCTACGTCGGCGACCTCTCCCCTGCCGACAAGCGTCAGGT
TGAAAAAAGCAAAGGGTTTGAAGAGGTTATGATGGAAGCCGGTTTGAAATTAAGTCGAAACAGTATTTTAAATACTAATG
GGTTAAGCTGGTATAACGGTTATACCGCTGCGAAAAAACTATTACAACAAACCCCAAAACCTACAGCAATCATTAGCGGA
AGCTACGATATCAGTGTAGGGATTTTACGAGCCGTAAAGGAACAACAGCTCAGTATACCCGAAGACCTATCTTTAATTTC
TTATGATAATATCCCTCAAATGGCAAGCCTTGAAACCCCGCTGACGAGCGTAGGGGTTCCAATCGATCAATTGGCTCACA
AAATGGTCGATTCTCTGCTGTCTCTTATTCGCGAGCCGGGCTCAATACCATTAACTCAAAAAATGGACCCTGAATTAAAC
GTAAGAATGTCATGCGCTTCTCCAGCAGTTTTAGGTGAAGAAAACAAGTAA

Upstream 100 bases:

>100_bases
GATGTATCATTTATAATAACAACGTTGTTATTTATTATCATAAAATTATTTTTGAAAATTTGCAATATTATATTTTTAAA
GATGTTTTGGAGGGTCCAAA

Downstream 100 bases:

>100_bases
CATTTAAGACGAGTTTTTCAGGTCATCTTTTCTTTTAAAAGCTGATGGCAATGGATTTTACAGAATTCCTCGGTACATTG
ATTTCTGAATTTTTACATGA

Product: hypothetical protein

Products: NA

Alternate protein names: Catabolite control protein [H]

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MTVTIKDIANASGVSYSTVSKALRNSPLVKPDTKKKVLQVAEQLGYSPNFAARSLASKKSQTIGLVWPTIERIALSALVT
KINEVVEKNNYSMILSVNRAKEAVDLFKSFRVDGIMIFEEGGETQLSDDTGLTIPILSYGVSGEHTHPIIDVNHKKAIYK
AVAYLYQLGHKNISYVGDLSPADKRQVEKSKGFEEVMMEAGLKLSRNSILNTNGLSWYNGYTAAKKLLQQTPKPTAIISG
SYDISVGILRAVKEQQLSIPEDLSLISYDNIPQMASLETPLTSVGVPIDQLAHKMVDSLLSLIREPGSIPLTQKMDPELN
VRMSCASPAVLGEENK

Sequences:

>Translated_336_residues
MTVTIKDIANASGVSYSTVSKALRNSPLVKPDTKKKVLQVAEQLGYSPNFAARSLASKKSQTIGLVWPTIERIALSALVT
KINEVVEKNNYSMILSVNRAKEAVDLFKSFRVDGIMIFEEGGETQLSDDTGLTIPILSYGVSGEHTHPIIDVNHKKAIYK
AVAYLYQLGHKNISYVGDLSPADKRQVEKSKGFEEVMMEAGLKLSRNSILNTNGLSWYNGYTAAKKLLQQTPKPTAIISG
SYDISVGILRAVKEQQLSIPEDLSLISYDNIPQMASLETPLTSVGVPIDQLAHKMVDSLLSLIREPGSIPLTQKMDPELN
VRMSCASPAVLGEENK
>Mature_335_residues
TVTIKDIANASGVSYSTVSKALRNSPLVKPDTKKKVLQVAEQLGYSPNFAARSLASKKSQTIGLVWPTIERIALSALVTK
INEVVEKNNYSMILSVNRAKEAVDLFKSFRVDGIMIFEEGGETQLSDDTGLTIPILSYGVSGEHTHPIIDVNHKKAIYKA
VAYLYQLGHKNISYVGDLSPADKRQVEKSKGFEEVMMEAGLKLSRNSILNTNGLSWYNGYTAAKKLLQQTPKPTAIISGS
YDISVGILRAVKEQQLSIPEDLSLISYDNIPQMASLETPLTSVGVPIDQLAHKMVDSLLSLIREPGSIPLTQKMDPELNV
RMSCASPAVLGEENK

Specific function: Transcriptional regulator involved in both the repression of carbohydrate utilization genes such as the alpha- amylase (amyE) and the acetyl-coenzyme A synthetase (acsA); and in the positive regulation of genes involved in excretion of excess carbon such

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789068, Length=318, Percent_Identity=27.3584905660377, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1787948, Length=338, Percent_Identity=28.698224852071, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1790369, Length=330, Percent_Identity=26.969696969697, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1790194, Length=314, Percent_Identity=26.4331210191083, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1788474, Length=312, Percent_Identity=27.2435897435897, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1786540, Length=313, Percent_Identity=27.4760383386581, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790715, Length=300, Percent_Identity=24.6666666666667, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI48994940, Length=310, Percent_Identity=23.8709677419355, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1787580, Length=319, Percent_Identity=26.3322884012539, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1789456, Length=331, Percent_Identity=25.3776435045317, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790689, Length=296, Percent_Identity=25.3378378378378, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1789202, Length=343, Percent_Identity=24.198250728863, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787906, Length=324, Percent_Identity=24.3827160493827, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006377
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36723; Mature: 36592

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVTIKDIANASGVSYSTVSKALRNSPLVKPDTKKKVLQVAEQLGYSPNFAARSLASKKS
CEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCC
QTIGLVWPTIERIALSALVTKINEVVEKNNYSMILSVNRAKEAVDLFKSFRVDGIMIFEE
CEEEEECHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHCCCEEEEEEC
GGETQLSDDTGLTIPILSYGVSGEHTHPIIDVNHKKAIYKAVAYLYQLGHKNISYVGDLS
CCCCCCCCCCCCEEEHEEECCCCCCCCCEEECCHHHHHHHHHHHHHHHCCCCCCEECCCC
PADKRQVEKSKGFEEVMMEAGLKLSRNSILNTNGLSWYNGYTAAKKLLQQTPKPTAIISG
CHHHHHHHHHCCHHHHHHHCCCEECCCCCCCCCCCCHHCCHHHHHHHHHHCCCCCEEEEC
SYDISVGILRAVKEQQLSIPEDLSLISYDNIPQMASLETPLTSVGVPIDQLAHKMVDSLL
CCCHHHHHHHHHHHHHCCCCCCCCEEECCCCCCHHHCCCCHHHHCCCHHHHHHHHHHHHH
SLIREPGSIPLTQKMDPELNVRMSCASPAVLGEENK
HHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCC
>Mature Secondary Structure 
TVTIKDIANASGVSYSTVSKALRNSPLVKPDTKKKVLQVAEQLGYSPNFAARSLASKKS
EEEEECCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCC
QTIGLVWPTIERIALSALVTKINEVVEKNNYSMILSVNRAKEAVDLFKSFRVDGIMIFEE
CEEEEECHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHCCCEEEEEEC
GGETQLSDDTGLTIPILSYGVSGEHTHPIIDVNHKKAIYKAVAYLYQLGHKNISYVGDLS
CCCCCCCCCCCCEEEHEEECCCCCCCCCEEECCHHHHHHHHHHHHHHHCCCCCCEECCCC
PADKRQVEKSKGFEEVMMEAGLKLSRNSILNTNGLSWYNGYTAAKKLLQQTPKPTAIISG
CHHHHHHHHHCCHHHHHHHCCCEECCCCCCCCCCCCHHCCHHHHHHHHHHCCCCCEEEEC
SYDISVGILRAVKEQQLSIPEDLSLISYDNIPQMASLETPLTSVGVPIDQLAHKMVDSLL
CCCHHHHHHHHHHHHHCCCCCCCCEEECCCCCCHHHCCCCHHHHCCCHHHHHHHHHHHHH
SLIREPGSIPLTQKMDPELNVRMSCASPAVLGEENK
HHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8200532 [H]