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The map label for this gene is adhR [H]

Identifier: 52785851

GI number: 52785851

Start: 2041405

End: 2041800

Strand: Direct

Name: adhR [H]

Synonym: BLi02098

Alternate gene names: 52785851

Gene position: 2041405-2041800 (Clockwise)

Preceding gene: 52785843

Following gene: 52785862

Centisome position: 48.34

GC content: 36.36

Gene sequence:

>396_bases
ATGGGGTATTCTATAAAAGAAGTTGCTGAAAAAGTAGGTTTGCCTACACATACACTCCGATATTATGAAAAAGAAGGTCT
TCTGCCTTTTATTAAAAGAGACGCAAATGGAAACCGCATTTTTGAAGAAAAAGACTTGTCATGGTTGGAGCTTGTGATAT
GCTTGCGGAAAACTGACATTGCGCTTTCGGAATTACGGGAAATCGTCAATTTAACAAAAGAAGGAGATTGGACCATCTCG
AAGCGCAAACAAATACTTGAAAAACATAAAGAAAAAATGCTTGAAAAGCAAAGAGTCCTGGAACGCGCCTTTTTAAAAAT
CGATGAGAAAATCATGTACTATGATGGATTAGAAAAAAAGAATCAGGCAATGTCCTTGAAAGCGGATGAAAAGTAA

Upstream 100 bases:

>100_bases
TCTTCTTCGGCTTGCGTTAAAGTCCACTTTAAGGTCTATAATCATTGTGTGTTGTGACACATCCAATTAGAATTTTGATG
AATATGATGGAGGTTTCAAA

Downstream 100 bases:

>100_bases
TTTGATAAGTGCCGGCGCGCTTTCAATTATGGCACTACATTCAAAAGAAATTTTTCCAAAGTCTCCTTTGCGGCTTGCTC
ATCCGTACCATAGACCATTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 131; Mature: 130

Protein sequence:

>131_residues
MGYSIKEVAEKVGLPTHTLRYYEKEGLLPFIKRDANGNRIFEEKDLSWLELVICLRKTDIALSELREIVNLTKEGDWTIS
KRKQILEKHKEKMLEKQRVLERAFLKIDEKIMYYDGLEKKNQAMSLKADEK

Sequences:

>Translated_131_residues
MGYSIKEVAEKVGLPTHTLRYYEKEGLLPFIKRDANGNRIFEEKDLSWLELVICLRKTDIALSELREIVNLTKEGDWTIS
KRKQILEKHKEKMLEKQRVLERAFLKIDEKIMYYDGLEKKNQAMSLKADEK
>Mature_130_residues
GYSIKEVAEKVGLPTHTLRYYEKEGLLPFIKRDANGNRIFEEKDLSWLELVICLRKTDIALSELREIVNLTKEGDWTISK
RKQILEKHKEKMLEKQRVLERAFLKIDEKIMYYDGLEKKNQAMSLKADEK

Specific function: Transcriptional regulator involved in the response to aldehyde stress. Binds to the promoter region of the adhA-yraA operon, the yraC and its own promoter region; binding is unchanged in the presence of aldehydes [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 15531; Mature: 15400

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYSIKEVAEKVGLPTHTLRYYEKEGLLPFIKRDANGNRIFEEKDLSWLELVICLRKTDI
CCCCHHHHHHHHCCCHHHHHHHHHCCCCHHHHCCCCCCCCCCHHCHHHHHHHHHHHHCCH
ALSELREIVNLTKEGDWTISKRKQILEKHKEKMLEKQRVLERAFLKIDEKIMYYDGLEKK
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
NQAMSLKADEK
CCCCCCCCCCC
>Mature Secondary Structure 
GYSIKEVAEKVGLPTHTLRYYEKEGLLPFIKRDANGNRIFEEKDLSWLELVICLRKTDI
CCCHHHHHHHHCCCHHHHHHHHHCCCCHHHHCCCCCCCCCCHHCHHHHHHHHHHHHCCH
ALSELREIVNLTKEGDWTISKRKQILEKHKEKMLEKQRVLERAFLKIDEKIMYYDGLEKK
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
NQAMSLKADEK
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9141695; 9384377 [H]