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The map label for this gene is yjbP

Identifier: 52785028

GI number: 52785028

Start: 1268283

End: 1269023

Strand: Reverse

Name: yjbP

Synonym: BLi01257

Alternate gene names: 52785028

Gene position: 1269023-1268283 (Counterclockwise)

Preceding gene: 52785039

Following gene: 52785023

Centisome position: 30.05

GC content: 49.53

Gene sequence:

>741_bases
ATGAAATACGATGTTATCGGTGATATTCACGGGTGCTATGACGAAATGATTGCGCTGATTGAAAAACTCGGCTACTCGCT
GACATCAGGAGTTCCCGTTCATCCGGAGAACAGAACACTTGTCTTTCTCGGGGATTTAACTGACAGAGGGCCAAAATCGC
TGGAGGTCGTTGAATTTGTAGGACGGGCCGTTGAAGATGGAGCTGTGCGATATGTGCCCGGCAATCATTGCAACAAGCTG
TACCGTTTTTTCAAGGGAAATCCGGTGAAGCTGCAGCACGGACTGGAAACGACGGCGGCCGAATACAGAAACCTTCCGAA
ACAAAAACAGAAGGATATCAGAGACCTTTTCATGCGCCTTTACGAAAAGGCTCCGCTTTACGAGATCCTGCATAACGGCG
AACTTGTCGTTGCACATGCCGGCATCAAAGCGGAAGACATCGGCAAAAAGCCTGTCGGAAAAGTAAAACAGTTTGTGCTC
TACGGAGATATTACAGGGGAAACGCTGCCAGACGGACGGCCAGTGAGACGGGACTGGGCCGCTCATTACAGAGGCGAGCC
GTGGGTTGTATACGGCCATACTCCCGTCAAAAACCCGAGGATGATTCATCATACAATTAATATCGATACCGGTTGTGTAT
TCGGCAACAGGCTGACCGCTTTCAGATTCCCGGAACTGACAACCGAATCTGTTCCCTCCTCTTTGCCTTATGATGAGTCT
AGATTCCGCATGGAGCCATAA

Upstream 100 bases:

>100_bases
GCCTGATTTTCTCCGGAGAAAGTTGCAGAAGCTTGATTTATACGGCTTGGGGCAATGTATATACATATGAAAAACAAACG
GACTGGAGGCGAAAAAACGC

Downstream 100 bases:

>100_bases
AAATAGAGAGCCTATTCAGCTCTCTATCAACTGTCTCATATCATTCGGCACCGGCGCTTGGAACGTCAGCTCTTCCATTG
TGAACGGATGAAAAAATGTC

Product: bis(5'-nucleosyl)-tetraphosphatase PrpE

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase; Diadenosine tetraphosphatase

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MKYDVIGDIHGCYDEMIALIEKLGYSLTSGVPVHPENRTLVFLGDLTDRGPKSLEVVEFVGRAVEDGAVRYVPGNHCNKL
YRFFKGNPVKLQHGLETTAAEYRNLPKQKQKDIRDLFMRLYEKAPLYEILHNGELVVAHAGIKAEDIGKKPVGKVKQFVL
YGDITGETLPDGRPVRRDWAAHYRGEPWVVYGHTPVKNPRMIHHTINIDTGCVFGNRLTAFRFPELTTESVPSSLPYDES
RFRMEP

Sequences:

>Translated_246_residues
MKYDVIGDIHGCYDEMIALIEKLGYSLTSGVPVHPENRTLVFLGDLTDRGPKSLEVVEFVGRAVEDGAVRYVPGNHCNKL
YRFFKGNPVKLQHGLETTAAEYRNLPKQKQKDIRDLFMRLYEKAPLYEILHNGELVVAHAGIKAEDIGKKPVGKVKQFVL
YGDITGETLPDGRPVRRDWAAHYRGEPWVVYGHTPVKNPRMIHHTINIDTGCVFGNRLTAFRFPELTTESVPSSLPYDES
RFRMEP
>Mature_246_residues
MKYDVIGDIHGCYDEMIALIEKLGYSLTSGVPVHPENRTLVFLGDLTDRGPKSLEVVEFVGRAVEDGAVRYVPGNHCNKL
YRFFKGNPVKLQHGLETTAAEYRNLPKQKQKDIRDLFMRLYEKAPLYEILHNGELVVAHAGIKAEDIGKKPVGKVKQFVL
YGDITGETLPDGRPVRRDWAAHYRGEPWVVYGHTPVKNPRMIHHTINIDTGCVFGNRLTAFRFPELTTESVPSSLPYDES
RFRMEP

Specific function: Asymmetrically hydrolyzes Ap4p to yield AMP and ATP

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prpE family

Homologues:

Organism=Escherichia coli, GI1786234, Length=150, Percent_Identity=34.6666666666667, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRPE_BACLD (Q65LA0)

Other databases:

- EMBL:   CP000002
- EMBL:   AE017333
- RefSeq:   YP_078457.1
- RefSeq:   YP_090857.1
- ProteinModelPortal:   Q65LA0
- SMR:   Q65LA0
- STRING:   Q65LA0
- EnsemblBacteria:   EBBACT00000054649
- EnsemblBacteria:   EBBACT00000060298
- GeneID:   3030263
- GeneID:   3100058
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi01257
- KEGG:   bli:BL05112
- NMPDR:   fig|279010.5.peg.2474
- eggNOG:   COG0639
- GeneTree:   EBGT00050000002430
- HOGENOM:   HBG724457
- OMA:   HCNKLYR
- ProtClustDB:   PRK13625
- BioCyc:   BLIC279010-1:BLI01257-MONOMER
- BioCyc:   BLIC279010:BL05112-MONOMER
- HAMAP:   MF_01443
- InterPro:   IPR004843
- InterPro:   IPR006186
- PANTHER:   PTHR11668
- PRINTS:   PR00114

Pfam domain/function: PF00149 Metallophos

EC number: =3.6.1.17

Molecular weight: Translated: 27936; Mature: 27936

Theoretical pI: Translated: 8.10; Mature: 8.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYDVIGDIHGCYDEMIALIEKLGYSLTSGVPVHPENRTLVFLGDLTDRGPKSLEVVEFV
CCCCCCCCHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHH
GRAVEDGAVRYVPGNHCNKLYRFFKGNPVKLQHGLETTAAEYRNLPKQKQKDIRDLFMRL
HHHHCCCEEEECCCHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHH
YEKAPLYEILHNGELVVAHAGIKAEDIGKKPVGKVKQFVLYGDITGETLPDGRPVRRDWA
HHHCCHHHHHCCCCEEEEECCCCHHHCCCCCHHHHHEEEEEECCCCCCCCCCCCCHHHHH
AHYRGEPWVVYGHTPVKNPRMIHHTINIDTGCVFGNRLTAFRFPELTTESVPSSLPYDES
HHCCCCCEEEECCCCCCCCEEEEEEEECCCCEEECCCCCEEECCCCCHHHCCCCCCCCCC
RFRMEP
CCCCCC
>Mature Secondary Structure
MKYDVIGDIHGCYDEMIALIEKLGYSLTSGVPVHPENRTLVFLGDLTDRGPKSLEVVEFV
CCCCCCCCHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHH
GRAVEDGAVRYVPGNHCNKLYRFFKGNPVKLQHGLETTAAEYRNLPKQKQKDIRDLFMRL
HHHHCCCEEEECCCHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHH
YEKAPLYEILHNGELVVAHAGIKAEDIGKKPVGKVKQFVLYGDITGETLPDGRPVRRDWA
HHHCCHHHHHCCCCEEEEECCCCHHHCCCCCHHHHHEEEEEECCCCCCCCCCCCCHHHHH
AHYRGEPWVVYGHTPVKNPRMIHHTINIDTGCVFGNRLTAFRFPELTTESVPSSLPYDES
HHCCCCCEEEECCCCCCCCEEEEEEEECCCCEEECCCCCEEECCCCCHHHCCCCCCCCCC
RFRMEP
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA