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The map label for this gene is lytE [H]

Identifier: 52784780

GI number: 52784780

Start: 1010729

End: 1011562

Strand: Direct

Name: lytE [H]

Synonym: BLi01008

Alternate gene names: 52784780

Gene position: 1010729-1011562 (Clockwise)

Preceding gene: 52784779

Following gene: 52784782

Centisome position: 23.94

GC content: 44.72

Gene sequence:

>834_bases
ATGAAAAAACAAGTAATAACAGCAGCATCAGCGGTTGTTTTAGGATCGACTTTGTTTGCGGGAGCCGCTTCCGCGCAAAC
CATAACGGTGAAAAAAGGAGACACGTTATGGGGTTTTTCGAAGAAGTATGGCACAACTGTCAGCAAGATTAAACAGGAAA
ACAAGCTGAAATCCGATATCATTTACATAGGACAGAGGCTGTCGATCAATGGAAGCAGTTCTTCGTCTGCAAAAGCGTCG
AAAGTTTCATCAGCTACGCATAAAGTGGTCAAAGGAGACAGCCTTTGGAAAATTTCGCGGACATACGGCATGACTGTTAA
CGAACTGAAAACTCTGAACGGTTTAAAAACAGATTTAATCCGGATTGGACAAGTATTAAAAGTCAAAGGGACGAAAAGCG
TAAAAGCAGCATCAACAACCAAGCCTTCCGCATCAAGCGGGACAAGCAAAACAAGCGCACCTGCGCAGAAATCTTCAACG
CTGAATACGTCAAAACTTGTTTCTGATGCAAAAGCCCTTATCGGAACGCCTTATAAATGGGGCGGAACATCTACATCAGG
ATTTGACTGCAGCGGGTTTGTCTGGTACATCCTCAACAAACAGACAAATGTAGCGAGAACGAATACAGTCGGATACTGGA
ATTCAATGAAGAGCGTATCAAGCCCGGCAGTAGGCGATTTCGTATTCTTCACGACATATCAGCCGGGACCTTCGCATATG
GGGGTTTACATCGGAAACAATCAATTCGTTCATGCCGGTTCTGACGGCGTAACGATCAGCGATATGACAAACAGCTATTG
GAAGCCCCGCTATCTTGGAGCAAAACGCTTCTAA

Upstream 100 bases:

>100_bases
ATAGAAGCAGAGGAAGGGCTGAAGCAGCCGTTCTCAAAAAAATGAAACTGCTAATTTTCGCCTTTGAAAATATAAAATAT
TCTGCTATTGGGAGGACAAC

Downstream 100 bases:

>100_bases
TGTTGCAGGGACAAGCCCGTTCATCATGATGAACGGGTTTTTTCCGTTTAGAAACGGAACTCGGCTAAAAACGCCAAAAA
GTGCTCGACCTTCTCATTAT

Product: hypothetical protein

Products: NA

Alternate protein names: Cell wall-associated polypeptide CWBP33; Gamma-D-glutamate-meso-diaminopimelate muropeptidase lytE; Phosphatase-associated protein papQ [H]

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MKKQVITAASAVVLGSTLFAGAASAQTITVKKGDTLWGFSKKYGTTVSKIKQENKLKSDIIYIGQRLSINGSSSSSAKAS
KVSSATHKVVKGDSLWKISRTYGMTVNELKTLNGLKTDLIRIGQVLKVKGTKSVKAASTTKPSASSGTSKTSAPAQKSST
LNTSKLVSDAKALIGTPYKWGGTSTSGFDCSGFVWYILNKQTNVARTNTVGYWNSMKSVSSPAVGDFVFFTTYQPGPSHM
GVYIGNNQFVHAGSDGVTISDMTNSYWKPRYLGAKRF

Sequences:

>Translated_277_residues
MKKQVITAASAVVLGSTLFAGAASAQTITVKKGDTLWGFSKKYGTTVSKIKQENKLKSDIIYIGQRLSINGSSSSSAKAS
KVSSATHKVVKGDSLWKISRTYGMTVNELKTLNGLKTDLIRIGQVLKVKGTKSVKAASTTKPSASSGTSKTSAPAQKSST
LNTSKLVSDAKALIGTPYKWGGTSTSGFDCSGFVWYILNKQTNVARTNTVGYWNSMKSVSSPAVGDFVFFTTYQPGPSHM
GVYIGNNQFVHAGSDGVTISDMTNSYWKPRYLGAKRF
>Mature_277_residues
MKKQVITAASAVVLGSTLFAGAASAQTITVKKGDTLWGFSKKYGTTVSKIKQENKLKSDIIYIGQRLSINGSSSSSAKAS
KVSSATHKVVKGDSLWKISRTYGMTVNELKTLNGLKTDLIRIGQVLKVKGTKSVKAASTTKPSASSGTSKTSAPAQKSST
LNTSKLVSDAKALIGTPYKWGGTSTSGFDCSGFVWYILNKQTNVARTNTVGYWNSMKSVSSPAVGDFVFFTTYQPGPSHM
GVYIGNNQFVHAGSDGVTISDMTNSYWKPRYLGAKRF

Specific function: Cleaves gamma-D-glutamate-meso-diaminopimelate bonds. Cell wall hydrolase involved in cell autolysis [H]

COG id: COG0791

COG function: function code M; Cell wall-associated hydrolases (invasion-associated proteins)

Gene ontology:

Cell location: Secreted, cell wall. Note=LysM repeats are thought to be involved in peptidoglycan binding [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 LysM repeats [H]

Homologues:

Organism=Escherichia coli, GI1787944, Length=145, Percent_Identity=34.4827586206897, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788501, Length=173, Percent_Identity=33.5260115606936, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1786421, Length=112, Percent_Identity=36.6071428571429, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788001, Length=142, Percent_Identity=34.5070422535211, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000064
- InterPro:   IPR018392
- InterPro:   IPR002482 [H]

Pfam domain/function: PF01476 LysM; PF00877 NLPC_P60 [H]

EC number: NA

Molecular weight: Translated: 29549; Mature: 29549

Theoretical pI: Translated: 10.80; Mature: 10.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKQVITAASAVVLGSTLFAGAASAQTITVKKGDTLWGFSKKYGTTVSKIKQENKLKSDI
CCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEECCCHHHCHHHHHHHHHHHHHHCE
IYIGQRLSINGSSSSSAKASKVSSATHKVVKGDSLWKISRTYGMTVNELKTLNGLKTDLI
EEECCEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEHHHCCCHHHHHHHCCHHHHHH
RIGQVLKVKGTKSVKAASTTKPSASSGTSKTSAPAQKSSTLNTSKLVSDAKALIGTPYKW
HHCCEEEECCCCCEEECCCCCCCCCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHCCCCCC
GGTSTSGFDCSGFVWYILNKQTNVARTNTVGYWNSMKSVSSPAVGDFVFFTTYQPGPSHM
CCCCCCCCCCCCEEEEEEECCCCCEECCCCCHHHHHHHCCCCCCCCEEEEEEECCCCCCE
GVYIGNNQFVHAGSDGVTISDMTNSYWKPRYLGAKRF
EEEECCCEEEEECCCCEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKKQVITAASAVVLGSTLFAGAASAQTITVKKGDTLWGFSKKYGTTVSKIKQENKLKSDI
CCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEECCCHHHCHHHHHHHHHHHHHHCE
IYIGQRLSINGSSSSSAKASKVSSATHKVVKGDSLWKISRTYGMTVNELKTLNGLKTDLI
EEECCEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEHHHCCCHHHHHHHCCHHHHHH
RIGQVLKVKGTKSVKAASTTKPSASSGTSKTSAPAQKSSTLNTSKLVSDAKALIGTPYKW
HHCCEEEECCCCCEEECCCCCCCCCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHCCCCCC
GGTSTSGFDCSGFVWYILNKQTNVARTNTVGYWNSMKSVSSPAVGDFVFFTTYQPGPSHM
CCCCCCCCCCCCEEEEEEECCCCCEECCCCCHHHHHHHCCCCCCCCEEEEEEECCCCCCE
GVYIGNNQFVHAGSDGVTISDMTNSYWKPRYLGAKRF
EEEECCCEEEEECCCCEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9457885; 9579061; 9384377; 8045898 [H]