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The map label for this gene is yhcY [H]

Identifier: 52784772

GI number: 52784772

Start: 1003553

End: 1004701

Strand: Direct

Name: yhcY [H]

Synonym: BLi01000

Alternate gene names: 52784772

Gene position: 1003553-1004701 (Clockwise)

Preceding gene: 52784771

Following gene: 52784773

Centisome position: 23.77

GC content: 51.35

Gene sequence:

>1149_bases
TTGCGGGAAGACACACAGTTTGAAAAACTGAAAACGCTCAAAGAAATAGCGGAAACTTTAAACGAAGGGAACGATCTAAA
GGAAACGCTCCATGCCGTTTTAAAGAAGCTGCTCCGCCTAACGGGACTCAAAACGGCATGGCTTTTTCTGATCGATGAAA
AGGGGAGCTTTGAACTGGCTGCTTCGGCCCGCCTGCCTCAAGCCCTTTCTTACCGGCAAAACCGTTTACTATGCGAAGGA
AGCTGCTACTGTCTTGAACAATACAGGGACGAAAAGCTGGACAGGGCGAAAAATATCATCCACTGCCGGCGGATTACGAC
GGCCATGAAACAGAAGACAGGAGATCCGGAAGGCATCACCCATCATGCAACCGTCCCGCTCAGTGACCAAAAGAAGCGGT
TCGGTTTGCTGAACGTTGCGGCACCGGGCAAAATTCATTTCAGCCGCGGGGAACTGGCGCTCCTCGAAGCTGTTGCTCTG
CAAATCGGGATGGCGATCAAACGGATGAGGCTTGCTGAACAACAGCAAAAACACCTGCTGCTGACCGAAAGAAACAGATT
GGCTCAGGACTTGCATGATTCCGTTAATCAAATGCTTTTTTCGCTCAGCTTGACCGCTAAAGCGGCGGGGGAAATGACAG
ACCAGCCGGAAATCAGGGAAATGCTCGAGTTTATGCAAAATCTTTCTCATGAAGCGCTTCTTGAGATGCGGGCGTTAATT
TGGCAGCTCAGGCCCCAGGGGCTGGAAGAAGGGTTAGCGGCGGCTCTTGAAAAATATGCGGAAGTGCTCGGCCTTCAAGT
AATCTTCAAGCTCAGCGATGTGCTCCGTCTGCCCCCTTCTGTTGAGGAATTGATGTGGCGGCTGAGCCAGGAAGCCCTCA
ACAATTGCAAAAAGCATGCCGGTGCAAGCCGCATACAAGTGAAAATCAATGTATTCCAGTCGTCTGCCGTCTTGGAAATC
GAAGATGACGGCAAAGGGTTTCAGTACGATCCTAATGTGGACATTCCGACGCTTGGGCTGAAAGGAATGAAGGAGCGGAC
GGAAAAAGCGGGCGGCACGCTTTTGATCACCTCCGCAATCGGTAAGGGGACAAAAATCCGGGCGGTTTTGCCTATGAAGG
AGAAGGGGGAGGCAGGATGGAGAAGGTGA

Upstream 100 bases:

>100_bases
TCGGTCAAAAGTCTTAGAAAAGATCATCTCATGAGGGCGGGCTTTTTTTTATCAACTATCGGTATAATGAAAGAAACTCC
GGTTTAAGGGGATGAAACTT

Downstream 100 bases:

>100_bases
AAATCATCATTGCCGATGATCATCATATTGTCAGAAAAGGGCTCTTGTTTTTCTTCAAAACAAAAAGCGATTTTGATGTT
ATCGGAGAGGCTTCGACAGG

Product: YhcY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MREDTQFEKLKTLKEIAETLNEGNDLKETLHAVLKKLLRLTGLKTAWLFLIDEKGSFELAASARLPQALSYRQNRLLCEG
SCYCLEQYRDEKLDRAKNIIHCRRITTAMKQKTGDPEGITHHATVPLSDQKKRFGLLNVAAPGKIHFSRGELALLEAVAL
QIGMAIKRMRLAEQQQKHLLLTERNRLAQDLHDSVNQMLFSLSLTAKAAGEMTDQPEIREMLEFMQNLSHEALLEMRALI
WQLRPQGLEEGLAAALEKYAEVLGLQVIFKLSDVLRLPPSVEELMWRLSQEALNNCKKHAGASRIQVKINVFQSSAVLEI
EDDGKGFQYDPNVDIPTLGLKGMKERTEKAGGTLLITSAIGKGTKIRAVLPMKEKGEAGWRR

Sequences:

>Translated_382_residues
MREDTQFEKLKTLKEIAETLNEGNDLKETLHAVLKKLLRLTGLKTAWLFLIDEKGSFELAASARLPQALSYRQNRLLCEG
SCYCLEQYRDEKLDRAKNIIHCRRITTAMKQKTGDPEGITHHATVPLSDQKKRFGLLNVAAPGKIHFSRGELALLEAVAL
QIGMAIKRMRLAEQQQKHLLLTERNRLAQDLHDSVNQMLFSLSLTAKAAGEMTDQPEIREMLEFMQNLSHEALLEMRALI
WQLRPQGLEEGLAAALEKYAEVLGLQVIFKLSDVLRLPPSVEELMWRLSQEALNNCKKHAGASRIQVKINVFQSSAVLEI
EDDGKGFQYDPNVDIPTLGLKGMKERTEKAGGTLLITSAIGKGTKIRAVLPMKEKGEAGWRR
>Mature_382_residues
MREDTQFEKLKTLKEIAETLNEGNDLKETLHAVLKKLLRLTGLKTAWLFLIDEKGSFELAASARLPQALSYRQNRLLCEG
SCYCLEQYRDEKLDRAKNIIHCRRITTAMKQKTGDPEGITHHATVPLSDQKKRFGLLNVAAPGKIHFSRGELALLEAVAL
QIGMAIKRMRLAEQQQKHLLLTERNRLAQDLHDSVNQMLFSLSLTAKAAGEMTDQPEIREMLEFMQNLSHEALLEMRALI
WQLRPQGLEEGLAAALEKYAEVLGLQVIFKLSDVLRLPPSVEELMWRLSQEALNNCKKHAGASRIQVKINVFQSSAVLEI
EDDGKGFQYDPNVDIPTLGLKGMKERTEKAGGTLLITSAIGKGTKIRAVLPMKEKGEAGWRR

Specific function: Member of the two-component regulatory system yhcY/yhcZ. Probably activates yhcZ by phosphorylation [H]

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787474, Length=247, Percent_Identity=25.9109311740891, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788812, Length=239, Percent_Identity=28.8702928870293, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR011712 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 43044; Mature: 43044

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREDTQFEKLKTLKEIAETLNEGNDLKETLHAVLKKLLRLTGLKTAWLFLIDEKGSFELA
CCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCEEEE
ASARLPQALSYRQNRLLCEGSCYCLEQYRDEKLDRAKNIIHCRRITTAMKQKTGDPEGIT
HHHCCHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
HHATVPLSDQKKRFGLLNVAAPGKIHFSRGELALLEAVALQIGMAIKRMRLAEQQQKHLL
EEEECCCCCCHHHCCEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTERNRLAQDLHDSVNQMLFSLSLTAKAAGEMTDQPEIREMLEFMQNLSHEALLEMRALI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHH
WQLRPQGLEEGLAAALEKYAEVLGLQVIFKLSDVLRLPPSVEELMWRLSQEALNNCKKHA
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHC
GASRIQVKINVFQSSAVLEIEDDGKGFQYDPNVDIPTLGLKGMKERTEKAGGTLLITSAI
CCCEEEEEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEECC
GKGTKIRAVLPMKEKGEAGWRR
CCCCEEEEECCCHHCCCCCCCC
>Mature Secondary Structure
MREDTQFEKLKTLKEIAETLNEGNDLKETLHAVLKKLLRLTGLKTAWLFLIDEKGSFELA
CCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCEEEE
ASARLPQALSYRQNRLLCEGSCYCLEQYRDEKLDRAKNIIHCRRITTAMKQKTGDPEGIT
HHHCCHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
HHATVPLSDQKKRFGLLNVAAPGKIHFSRGELALLEAVALQIGMAIKRMRLAEQQQKHLL
EEEECCCCCCHHHCCEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTERNRLAQDLHDSVNQMLFSLSLTAKAAGEMTDQPEIREMLEFMQNLSHEALLEMRALI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHH
WQLRPQGLEEGLAAALEKYAEVLGLQVIFKLSDVLRLPPSVEELMWRLSQEALNNCKKHA
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHC
GASRIQVKINVFQSSAVLEIEDDGKGFQYDPNVDIPTLGLKGMKERTEKAGGTLLITSAI
CCCEEEEEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEECC
GKGTKIRAVLPMKEKGEAGWRR
CCCCEEEEECCCHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]