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The map label for this gene is yfkE [H]

Identifier: 52784622

GI number: 52784622

Start: 842730

End: 843785

Strand: Direct

Name: yfkE [H]

Synonym: BLi00823

Alternate gene names: 52784622

Gene position: 842730-843785 (Clockwise)

Preceding gene: 52784621

Following gene: 52784623

Centisome position: 19.96

GC content: 50.95

Gene sequence:

>1056_bases
ATGAGCCGTTTTTTCTTTTGGATGATGGCTGCGGGTGTTCCACTTTCTGTCGCAGGGAGCCTTCTGCATTGGCCGCAGGT
TTTATTGTTCATCATATACTGCCTGACGATCATCGCGCTTGCAAGCTATATGGGAAGAGCCACCGAAAGCCTTGCGATCA
TTGCGGGACCGAGGATCGGAGGCCTTTTAAATGCGACGTTCGGAAACGCCGTTGAGCTGATCATTTCGATTTTCGCGTTG
CGGGAAGGACTGATCGGAATTGTGCTCGCATCGCTGACAGGATCTGTCTTGGGCAACCTTCTCCTGGTCGCCGGGCTTTC
GTTTTTCATCGGGGGCCTGAAATATAAGCGCCAGGAATTCAACGTGTATGATGCGAGACACAATTCAGGTCTGCTCATGT
TCGCGGTGATTGTCGCTTTCGTTATCCCTGAAGTGTTTTCAGCTGAAATGACAGAGCCGAGGAAGCTGTCGATGAGCGTC
GGCATCAGCATCATCATGATTTTGCTTTACCTGGCTGCACTTTATTTCAAGCTTGTCAGCCACCGCGGGGTTTACCAGAC
GAATCAAAATGAGCAGGAAGAATCGCATGAAGAGCCGGAATGGTCGGGAAAGCGCGCAACATTGATCTTATTTTTGGCAA
CTGTTGCCGTCGCCTACATTTCCGAGCACCTCGTCCATACGTTTGATACGGTGGCCGAACAATTCGGCTGGTCGGAGCTT
TTCATCGGGGTCATCATTGTCGCGATCGTCGGAAACGCGGCAGAGCATGCTTCCGCCGTCATTATGGCCTATAAGGACAA
AATGGATGTCGCGGTTGAAATTGCGATCGGATCAACGCTTCAGATCGCGATGTTTGTCGCCCCTGTTCTTGTCATCAGCT
CTTTGTTTTTTCCAACGAGCATGCCGCTCGTCTTTACCTTGCCGGAGCTGGTCGCCATGGCTTCCGCCGTCCTTTTGATG
ATCATCATTTCCAACGACGGGGACACGAACTGGTTTGAAGGCGCGACATTGCTGGCCGCTTATATCATCATGGGAATCGG
TTTTTTCCTTCTTTAA

Upstream 100 bases:

>100_bases
TAAAAACATGCGCCGCTGCGGAATAGATCAGTATGCCGTATATAAAGCGAAAAGTTCGCACAAAAATAACCTACACCAAA
AAAGAAAAGAGGAATGAAAA

Downstream 100 bases:

>100_bases
AAAAATCGGGATAAACAGAGAGCATCCGGAAAACAATAAGGAAAAAGAAACAGAAAGAGTGATAGTATGAAAAAGCTTTT
GTGTTTTACGCTGACTGCGT

Product: YfkE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MSRFFFWMMAAGVPLSVAGSLLHWPQVLLFIIYCLTIIALASYMGRATESLAIIAGPRIGGLLNATFGNAVELIISIFAL
REGLIGIVLASLTGSVLGNLLLVAGLSFFIGGLKYKRQEFNVYDARHNSGLLMFAVIVAFVIPEVFSAEMTEPRKLSMSV
GISIIMILLYLAALYFKLVSHRGVYQTNQNEQEESHEEPEWSGKRATLILFLATVAVAYISEHLVHTFDTVAEQFGWSEL
FIGVIIVAIVGNAAEHASAVIMAYKDKMDVAVEIAIGSTLQIAMFVAPVLVISSLFFPTSMPLVFTLPELVAMASAVLLM
IIISNDGDTNWFEGATLLAAYIIMGIGFFLL

Sequences:

>Translated_351_residues
MSRFFFWMMAAGVPLSVAGSLLHWPQVLLFIIYCLTIIALASYMGRATESLAIIAGPRIGGLLNATFGNAVELIISIFAL
REGLIGIVLASLTGSVLGNLLLVAGLSFFIGGLKYKRQEFNVYDARHNSGLLMFAVIVAFVIPEVFSAEMTEPRKLSMSV
GISIIMILLYLAALYFKLVSHRGVYQTNQNEQEESHEEPEWSGKRATLILFLATVAVAYISEHLVHTFDTVAEQFGWSEL
FIGVIIVAIVGNAAEHASAVIMAYKDKMDVAVEIAIGSTLQIAMFVAPVLVISSLFFPTSMPLVFTLPELVAMASAVLLM
IIISNDGDTNWFEGATLLAAYIIMGIGFFLL
>Mature_350_residues
SRFFFWMMAAGVPLSVAGSLLHWPQVLLFIIYCLTIIALASYMGRATESLAIIAGPRIGGLLNATFGNAVELIISIFALR
EGLIGIVLASLTGSVLGNLLLVAGLSFFIGGLKYKRQEFNVYDARHNSGLLMFAVIVAFVIPEVFSAEMTEPRKLSMSVG
ISIIMILLYLAALYFKLVSHRGVYQTNQNEQEESHEEPEWSGKRATLILFLATVAVAYISEHLVHTFDTVAEQFGWSELF
IGVIIVAIVGNAAEHASAVIMAYKDKMDVAVEIAIGSTLQIAMFVAPVLVISSLFFPTSMPLVFTLPELVAMASAVLLMI
IISNDGDTNWFEGATLLAAYIIMGIGFFLL

Specific function: Unknown

COG id: COG0387

COG function: function code P; Ca2+/H+ antiporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320075, Length=351, Percent_Identity=41.3105413105413, Blast_Score=216, Evalue=6e-57,
Organism=Saccharomyces cerevisiae, GI6324008, Length=390, Percent_Identity=28.974358974359, Blast_Score=141, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004713
- InterPro:   IPR004798
- InterPro:   IPR004837 [H]

Pfam domain/function: PF01699 Na_Ca_ex [H]

EC number: NA

Molecular weight: Translated: 38189; Mature: 38058

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRFFFWMMAAGVPLSVAGSLLHWPQVLLFIIYCLTIIALASYMGRATESLAIIAGPRIG
CCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCC
GLLNATFGNAVELIISIFALREGLIGIVLASLTGSVLGNLLLVAGLSFFIGGLKYKRQEF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NVYDARHNSGLLMFAVIVAFVIPEVFSAEMTEPRKLSMSVGISIIMILLYLAALYFKLVS
CEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
HRGVYQTNQNEQEESHEEPEWSGKRATLILFLATVAVAYISEHLVHTFDTVAEQFGWSEL
CCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
FIGVIIVAIVGNAAEHASAVIMAYKDKMDVAVEIAIGSTLQIAMFVAPVLVISSLFFPTS
HHHHHHHHHHCCCHHHHHHHHEEECCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCC
MPLVFTLPELVAMASAVLLMIIISNDGDTNWFEGATLLAAYIIMGIGFFLL
CCHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
SRFFFWMMAAGVPLSVAGSLLHWPQVLLFIIYCLTIIALASYMGRATESLAIIAGPRIG
CHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCC
GLLNATFGNAVELIISIFALREGLIGIVLASLTGSVLGNLLLVAGLSFFIGGLKYKRQEF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NVYDARHNSGLLMFAVIVAFVIPEVFSAEMTEPRKLSMSVGISIIMILLYLAALYFKLVS
CEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
HRGVYQTNQNEQEESHEEPEWSGKRATLILFLATVAVAYISEHLVHTFDTVAEQFGWSEL
CCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
FIGVIIVAIVGNAAEHASAVIMAYKDKMDVAVEIAIGSTLQIAMFVAPVLVISSLFFPTS
HHHHHHHHHHCCCHHHHHHHHEEECCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCC
MPLVFTLPELVAMASAVLLMIIISNDGDTNWFEGATLLAAYIIMGIGFFLL
CCHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]