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The map label for this gene is ydgF [H]

Identifier: 52784405

GI number: 52784405

Start: 589123

End: 590505

Strand: Reverse

Name: ydgF [H]

Synonym: BLi00592

Alternate gene names: 52784405

Gene position: 590505-589123 (Counterclockwise)

Preceding gene: 52784412

Following gene: 52784404

Centisome position: 13.98

GC content: 47.36

Gene sequence:

>1383_bases
GTGACAGAAGATGTAACTGACAACGATATACACGAACAAAAATTATCGAGAGGCCTGAAAAACAGGCATATTCAGCTCAT
CGCCATCGGCGGGGCGATCGGAACGGGGCTGTTTCTTGGTTCGGGGAAATCAATCCATTTTGCAGGACCGTCGATTTTAT
TTGCTTATCTGATTACGGGAATCATTTGTTTTTTCATTATGCGTTCTCTTGGAGAACTGCTCTTATCCAATTTGGAATAC
CATTCGTTTGTCGACTTTGTAAGAGACTACTTAGGCGACATGGCGGCATTTATAACGGGGTGGACATACTGGTTTTGCTG
GATTTCGCTCGCAATGGCCGATTTAACCGCGGTCGGGCTTTATACCCAATACTGGCTGCCTGATGTACCGCAATGGCTGC
CCGGATTGATCGCCCTGATCATTTTGCTGATCATGAACCTGGCCACCGTCAAGCTTTTTGGAGAATTGGAGTTCTGGTTC
GCGTTAATCAAAGTCATTGCGATATTGGCGCTGATCGCGATCGGACTTTTCATGATCTTCAAAGGATTTTCTACCCATTC
GGGCACTGCCGCCTTTCACAACCTTTGGAGCCACGGCGGCATGTTTCCTAATGGACTGCACGGATTTCTCCTTTCATTCC
AGATGGTTGTCTTTGCGTTTGTAGGCATCGAACTTGTGGGGCTGACAGCGGGGGAAACGAAAGATCCCGAAAAGGTCATT
CCTAAAGCGATCAACAATATCCCCGTTCGGGTTTTGCTTTTTTATATCGGTGCGCTCCTTGTAATCATGAGCATCTATCC
GTGGAATGTCATCAATCCTAATGAGAGTCCGTTCGTCCAAGTCTTCGCAGCGGTCGGCATCATTGCGGCTGCAAGCATCA
TCAACTTTGTGGTGCTGACATCGGCGGCTTCGGCAAGCAACAGCGCAGTCTTCAGCACAAGCCGGATGATATACTCGCTC
GCGAAAGAACATAATGCGCCCGGCGCTATGACCAAACTGACCTCCCGCAAAGTGCCGGGCAATGCATTGTTTTTCTCAGC
GGTCGTTATTCTGATTGGCATCATGCTGAACTATATCATGCCTGAGCAAGTGTTTACGCTCATTACAAGCATCTCGACGA
TATGCTTCATCTTTATTTGGGGAATAACCGTCATCTGCCATTTGAAATACCGCAGAACTAGACCGGATTTAGCGAAAAGA
AACAAATTCAAGATGCCGCTTTACCCGTTTTCAAATTATGTGGTTCTCGGTTTTCTTGCGTTTATCCTCATTGTGCTCGC
ACTGGCGCAGGACACCCGTGTTTCCTTATTTGTCACGCCGGTTTGGTTTATCATGCTGATCGCGATTTACAAGCTGAGAA
AACCTAAGTCACGGCAAGTGTAG

Upstream 100 bases:

>100_bases
CAAGCCGATATGATCAATTACTTCAAATTTTAATGTTATAATAGATTTTAAAACATGCGGGAGATCAGGCTTAAAAACAA
AAAATGGAGGCATACATAAA

Downstream 100 bases:

>100_bases
AAAAAATGCGAATCGCCTGCAGAAAGTTCTGCGGGCTTTTTGTATGGCTCTTGCTGTAAAATTAAAAAGACAACAGCCGC
ACATCAATTCAATGGTCAGC

Product: YdgF

Products: D-glycine [Cytoplasm]; D-alanine [Cytoplasm]; Proton [Cytoplasm]; D-serine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 459

Protein sequence:

>460_residues
MTEDVTDNDIHEQKLSRGLKNRHIQLIAIGGAIGTGLFLGSGKSIHFAGPSILFAYLITGIICFFIMRSLGELLLSNLEY
HSFVDFVRDYLGDMAAFITGWTYWFCWISLAMADLTAVGLYTQYWLPDVPQWLPGLIALIILLIMNLATVKLFGELEFWF
ALIKVIAILALIAIGLFMIFKGFSTHSGTAAFHNLWSHGGMFPNGLHGFLLSFQMVVFAFVGIELVGLTAGETKDPEKVI
PKAINNIPVRVLLFYIGALLVIMSIYPWNVINPNESPFVQVFAAVGIIAAASIINFVVLTSAASASNSAVFSTSRMIYSL
AKEHNAPGAMTKLTSRKVPGNALFFSAVVILIGIMLNYIMPEQVFTLITSISTICFIFIWGITVICHLKYRRTRPDLAKR
NKFKMPLYPFSNYVVLGFLAFILIVLALAQDTRVSLFVTPVWFIMLIAIYKLRKPKSRQV

Sequences:

>Translated_460_residues
MTEDVTDNDIHEQKLSRGLKNRHIQLIAIGGAIGTGLFLGSGKSIHFAGPSILFAYLITGIICFFIMRSLGELLLSNLEY
HSFVDFVRDYLGDMAAFITGWTYWFCWISLAMADLTAVGLYTQYWLPDVPQWLPGLIALIILLIMNLATVKLFGELEFWF
ALIKVIAILALIAIGLFMIFKGFSTHSGTAAFHNLWSHGGMFPNGLHGFLLSFQMVVFAFVGIELVGLTAGETKDPEKVI
PKAINNIPVRVLLFYIGALLVIMSIYPWNVINPNESPFVQVFAAVGIIAAASIINFVVLTSAASASNSAVFSTSRMIYSL
AKEHNAPGAMTKLTSRKVPGNALFFSAVVILIGIMLNYIMPEQVFTLITSISTICFIFIWGITVICHLKYRRTRPDLAKR
NKFKMPLYPFSNYVVLGFLAFILIVLALAQDTRVSLFVTPVWFIMLIAIYKLRKPKSRQV
>Mature_459_residues
TEDVTDNDIHEQKLSRGLKNRHIQLIAIGGAIGTGLFLGSGKSIHFAGPSILFAYLITGIICFFIMRSLGELLLSNLEYH
SFVDFVRDYLGDMAAFITGWTYWFCWISLAMADLTAVGLYTQYWLPDVPQWLPGLIALIILLIMNLATVKLFGELEFWFA
LIKVIAILALIAIGLFMIFKGFSTHSGTAAFHNLWSHGGMFPNGLHGFLLSFQMVVFAFVGIELVGLTAGETKDPEKVIP
KAINNIPVRVLLFYIGALLVIMSIYPWNVINPNESPFVQVFAAVGIIAAASIINFVVLTSAASASNSAVFSTSRMIYSLA
KEHNAPGAMTKLTSRKVPGNALFFSAVVILIGIMLNYIMPEQVFTLITSISTICFIFIWGITVICHLKYRRTRPDLAKRN
KFKMPLYPFSNYVVLGFLAFILIVLALAQDTRVSLFVTPVWFIMLIAIYKLRKPKSRQV

Specific function: Probable amino-acid or metabolite transport protein [H]

COG id: COG1113

COG function: function code E; Gamma-aminobutyrate permease and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI115648063, Length=463, Percent_Identity=23.5421166306695, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI115648022, Length=463, Percent_Identity=23.5421166306695, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI181337167, Length=338, Percent_Identity=23.0769230769231, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI4507047, Length=356, Percent_Identity=24.1573033707865, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI33286428, Length=449, Percent_Identity=23.3853006681514, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1790653, Length=460, Percent_Identity=53.9130434782609, Blast_Score=514, Evalue=1e-147,
Organism=Escherichia coli, GI1786789, Length=457, Percent_Identity=43.3260393873085, Blast_Score=411, Evalue=1e-116,
Organism=Escherichia coli, GI1786302, Length=454, Percent_Identity=41.1894273127753, Blast_Score=394, Evalue=1e-110,
Organism=Escherichia coli, GI48994972, Length=444, Percent_Identity=43.9189189189189, Blast_Score=389, Evalue=1e-109,
Organism=Escherichia coli, GI1786602, Length=450, Percent_Identity=44.6666666666667, Blast_Score=369, Evalue=1e-103,
Organism=Escherichia coli, GI87081915, Length=408, Percent_Identity=40.9313725490196, Blast_Score=340, Evalue=1e-94,
Organism=Escherichia coli, GI87081708, Length=457, Percent_Identity=33.4792122538293, Blast_Score=259, Evalue=2e-70,
Organism=Escherichia coli, GI1789017, Length=417, Percent_Identity=33.0935251798561, Blast_Score=258, Evalue=5e-70,
Organism=Escherichia coli, GI1788480, Length=460, Percent_Identity=34.7826086956522, Blast_Score=246, Evalue=2e-66,
Organism=Escherichia coli, GI87081869, Length=376, Percent_Identity=22.0744680851064, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17540018, Length=432, Percent_Identity=24.7685185185185, Blast_Score=76, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6324061, Length=490, Percent_Identity=31.4285714285714, Blast_Score=210, Evalue=3e-55,
Organism=Saccharomyces cerevisiae, GI6320772, Length=451, Percent_Identity=33.0376940133038, Blast_Score=202, Evalue=8e-53,
Organism=Saccharomyces cerevisiae, GI6324924, Length=451, Percent_Identity=31.9290465631929, Blast_Score=201, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6322892, Length=441, Percent_Identity=29.4784580498866, Blast_Score=176, Evalue=5e-45,
Organism=Saccharomyces cerevisiae, GI6324990, Length=457, Percent_Identity=29.7592997811816, Blast_Score=166, Evalue=7e-42,
Organism=Saccharomyces cerevisiae, GI6321053, Length=398, Percent_Identity=28.391959798995, Blast_Score=161, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6324059, Length=452, Percent_Identity=30.7522123893805, Blast_Score=160, Evalue=4e-40,
Organism=Saccharomyces cerevisiae, GI6321629, Length=454, Percent_Identity=26.8722466960352, Blast_Score=152, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6319608, Length=410, Percent_Identity=27.5609756097561, Blast_Score=149, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6319824, Length=414, Percent_Identity=26.8115942028986, Blast_Score=148, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6320717, Length=408, Percent_Identity=24.7549019607843, Blast_Score=146, Evalue=6e-36,
Organism=Saccharomyces cerevisiae, GI6324553, Length=392, Percent_Identity=28.3163265306122, Blast_Score=145, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6319543, Length=406, Percent_Identity=26.3546798029557, Blast_Score=139, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6319542, Length=412, Percent_Identity=25.7281553398058, Blast_Score=137, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6320251, Length=412, Percent_Identity=25, Blast_Score=134, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6322967, Length=420, Percent_Identity=25.2380952380952, Blast_Score=122, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6324981, Length=422, Percent_Identity=26.303317535545, Blast_Score=115, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6320364, Length=486, Percent_Identity=25.5144032921811, Blast_Score=100, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 51178; Mature: 51047

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEDVTDNDIHEQKLSRGLKNRHIQLIAIGGAIGTGLFLGSGKSIHFAGPSILFAYLITG
CCCCCCCCHHHHHHHHCCHHHCCEEEEEECCHHHHHHEECCCCEEEECCHHHHHHHHHHH
IICFFIMRSLGELLLSNLEYHSFVDFVRDYLGDMAAFITGWTYWFCWISLAMADLTAVGL
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YTQYWLPDVPQWLPGLIALIILLIMNLATVKLFGELEFWFALIKVIAILALIAIGLFMIF
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGFSTHSGTAAFHNLWSHGGMFPNGLHGFLLSFQMVVFAFVGIELVGLTAGETKDPEKVI
HCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHH
PKAINNIPVRVLLFYIGALLVIMSIYPWNVINPNESPFVQVFAAVGIIAAASIINFVVLT
HHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SAASASNSAVFSTSRMIYSLAKEHNAPGAMTKLTSRKVPGNALFFSAVVILIGIMLNYIM
HCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
PEQVFTLITSISTICFIFIWGITVICHLKYRRTRPDLAKRNKFKMPLYPFSNYVVLGFLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCHHHHHHHHH
FILIVLALAQDTRVSLFVTPVWFIMLIAIYKLRKPKSRQV
HHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TEDVTDNDIHEQKLSRGLKNRHIQLIAIGGAIGTGLFLGSGKSIHFAGPSILFAYLITG
CCCCCCCHHHHHHHHCCHHHCCEEEEEECCHHHHHHEECCCCEEEECCHHHHHHHHHHH
IICFFIMRSLGELLLSNLEYHSFVDFVRDYLGDMAAFITGWTYWFCWISLAMADLTAVGL
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YTQYWLPDVPQWLPGLIALIILLIMNLATVKLFGELEFWFALIKVIAILALIAIGLFMIF
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGFSTHSGTAAFHNLWSHGGMFPNGLHGFLLSFQMVVFAFVGIELVGLTAGETKDPEKVI
HCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHH
PKAINNIPVRVLLFYIGALLVIMSIYPWNVINPNESPFVQVFAAVGIIAAASIINFVVLT
HHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SAASASNSAVFSTSRMIYSLAKEHNAPGAMTKLTSRKVPGNALFFSAVVILIGIMLNYIM
HCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
PEQVFTLITSISTICFIFIWGITVICHLKYRRTRPDLAKRNKFKMPLYPFSNYVVLGFLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCHHHHHHHHH
FILIVLALAQDTRVSLFVTPVWFIMLIAIYKLRKPKSRQV
HHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-glycine [Periplasm]; D-alanine [Periplasm]; Proton [Periplasm]; D-serine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + D-glycine [Periplasm] = Proton [Cytoplasm] + D-glycine [Cytoplasm] Proton [Periplasm] + D-alanine [Periplasm] = Proton [Cytoplasm] + D-alanine [Cytoplasm] Proton [Periplasm] + D-serine [Periplasm] = Proton [Cytoplasm] + D-serine [Cyto

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]