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The map label for this gene is yclF [H]

Identifier: 52784269

GI number: 52784269

Start: 449388

End: 450878

Strand: Reverse

Name: yclF [H]

Synonym: BLi00449

Alternate gene names: 52784269

Gene position: 450878-449388 (Counterclockwise)

Preceding gene: 52784272

Following gene: 52784268

Centisome position: 10.68

GC content: 48.69

Gene sequence:

>1491_bases
ATGTCAAACCATCAAAAAGAAACTTTTCAAAACATTCCGCAAAAGGGGTTTTTTGGACATCCCCGCGGACTCTTCACCTT
ATTCTTCACTGAATTTTGGGAGCGCTTTTCATACTACGGCATGAGAGCCATCCTTATCTATTATTTGTATACAGAGGTGA
CAAAAGGCGGCCTCGGGTTTGATCAAACGACAGCGAACTCGATTATGGCCGTATATGGTTCCCTCGTCTATATGTCCGGC
ATTATCGGGGGCTGGATAGCGGACAGGCTCCTCGGAACTGCAAACACCGTGTTTTACGGCGGCGTGCTCATTATGTTCGG
ACACATTCTTTTGTCATTCCCGGGAAGCGTCCCCGCTTTCTTCATCAGCATGTTCTTGATCATCATTGGGACAGGCCTTT
TAAAACCTAACGTATCAAGCGTTGTCGGCGATTTGTACAGCCCTGAAGACACCCGCCGCGATTCTGGTTTCAGCATCTTC
TATATGGGAATCAACCTTGGCGGATTTCTCGCGCCGATTATCGTCGGCACAGTCGGTCAGACATACAACTACCATCTCGG
CTTCAGCCTTGCTGCCATCGGCATGTTGTTCGGACTGCTGACCTATTTAGCGACGCGGAAGAAAAACCTCGGATCTGCCG
GAAGAACGGTACCGAATCCGCTCACACCAGCTGAAAGGAAAATGGTGTTCGGACGGATCGGGATCGGTGTTTTGGTGATC
GCTGCCATCTTTGGCTATTCCATCTTTATGGGCTGGATGACAATCAAGCTGTTTACGATGATCGTCAGCTGTCTCGGCAT
TTTGATCCCGCTGATTTATTTCATCGTCATGTTTAAAAGCTCCAAGACGACGAGTGATGAACGTTCCCGTCTCACAGCTT
ACATTCCGCTGTTTGTCGCATCGATGATGTTTTGGGCGATTCAGGAACAAGGCGCCAATATTTTAGCCACCTATGCAGAT
AAACGCACTCATTTGGAATTTTTAGGTGTCCAATTGCACTCTTCTTGGTTCCAGTCGCTGAATCCGTTGTTCATCGTTGT
GCTTGCACCGGTTTTCGCATGGATTTGGATGAGGCTCGGAAACCGTCAGCCGTCAACGCCGACGAAGTTTTCACTCGGGT
TGATTTTAGCCGGACTGTCATTTGTCGTCATGATTTTCCCTGCTTACATCAACGGCACTGAATCGCTTGCCAATCCAATG
TGGCTTGTGCTCAGCTTCCTGATCGTCGTTCTCGGGGAATTGTGCTTGTCTCCAGTCGGGTTATCCGCAACGTCAAAGCT
GGCTCCTGCTGCTTTCTCAGCGCAGACGATGAGTCTATGGTTCCTGTCAAACGCTTCTGCACAGGCCATCAACGCACAGA
TCGTCAGATTTTACAGCGTTGATACCGAGATCGCCTACTTCGGCATCATCGGCGGTGTATCCATCCTGCTCGGGATCATT
TTGATGCTGCTGTCACCGAAAATTCAGAAATTTATGAAGGGTGTTAATTAA

Upstream 100 bases:

>100_bases
CATCGATCAAAAATTCAAATCGATTGAAGGTGTATTGACACGAACATTATATAAGAATATGATTTTTATAATAGACATAG
AAAGAGAAGGAGTATTGCGA

Downstream 100 bases:

>100_bases
AAAGCAATAGGCTGATACTCCTTTTCTTCTGTTTTTTCGCAGGATATATACATTTCGATTTAATGAGAGATAGGGAATAC
CTGTTAAAGCAAAACCCCCG

Product: YclF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 496; Mature: 495

Protein sequence:

>496_residues
MSNHQKETFQNIPQKGFFGHPRGLFTLFFTEFWERFSYYGMRAILIYYLYTEVTKGGLGFDQTTANSIMAVYGSLVYMSG
IIGGWIADRLLGTANTVFYGGVLIMFGHILLSFPGSVPAFFISMFLIIIGTGLLKPNVSSVVGDLYSPEDTRRDSGFSIF
YMGINLGGFLAPIIVGTVGQTYNYHLGFSLAAIGMLFGLLTYLATRKKNLGSAGRTVPNPLTPAERKMVFGRIGIGVLVI
AAIFGYSIFMGWMTIKLFTMIVSCLGILIPLIYFIVMFKSSKTTSDERSRLTAYIPLFVASMMFWAIQEQGANILATYAD
KRTHLEFLGVQLHSSWFQSLNPLFIVVLAPVFAWIWMRLGNRQPSTPTKFSLGLILAGLSFVVMIFPAYINGTESLANPM
WLVLSFLIVVLGELCLSPVGLSATSKLAPAAFSAQTMSLWFLSNASAQAINAQIVRFYSVDTEIAYFGIIGGVSILLGII
LMLLSPKIQKFMKGVN

Sequences:

>Translated_496_residues
MSNHQKETFQNIPQKGFFGHPRGLFTLFFTEFWERFSYYGMRAILIYYLYTEVTKGGLGFDQTTANSIMAVYGSLVYMSG
IIGGWIADRLLGTANTVFYGGVLIMFGHILLSFPGSVPAFFISMFLIIIGTGLLKPNVSSVVGDLYSPEDTRRDSGFSIF
YMGINLGGFLAPIIVGTVGQTYNYHLGFSLAAIGMLFGLLTYLATRKKNLGSAGRTVPNPLTPAERKMVFGRIGIGVLVI
AAIFGYSIFMGWMTIKLFTMIVSCLGILIPLIYFIVMFKSSKTTSDERSRLTAYIPLFVASMMFWAIQEQGANILATYAD
KRTHLEFLGVQLHSSWFQSLNPLFIVVLAPVFAWIWMRLGNRQPSTPTKFSLGLILAGLSFVVMIFPAYINGTESLANPM
WLVLSFLIVVLGELCLSPVGLSATSKLAPAAFSAQTMSLWFLSNASAQAINAQIVRFYSVDTEIAYFGIIGGVSILLGII
LMLLSPKIQKFMKGVN
>Mature_495_residues
SNHQKETFQNIPQKGFFGHPRGLFTLFFTEFWERFSYYGMRAILIYYLYTEVTKGGLGFDQTTANSIMAVYGSLVYMSGI
IGGWIADRLLGTANTVFYGGVLIMFGHILLSFPGSVPAFFISMFLIIIGTGLLKPNVSSVVGDLYSPEDTRRDSGFSIFY
MGINLGGFLAPIIVGTVGQTYNYHLGFSLAAIGMLFGLLTYLATRKKNLGSAGRTVPNPLTPAERKMVFGRIGIGVLVIA
AIFGYSIFMGWMTIKLFTMIVSCLGILIPLIYFIVMFKSSKTTSDERSRLTAYIPLFVASMMFWAIQEQGANILATYADK
RTHLEFLGVQLHSSWFQSLNPLFIVVLAPVFAWIWMRLGNRQPSTPTKFSLGLILAGLSFVVMIFPAYINGTESLANPMW
LVLSFLIVVLGELCLSPVGLSATSKLAPAAFSAQTMSLWFLSNASAQAINAQIVRFYSVDTEIAYFGIIGGVSILLGIIL
MLLSPKIQKFMKGVN

Specific function: Unknown

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family [H]

Homologues:

Organism=Homo sapiens, GI4827008, Length=406, Percent_Identity=25.3694581280788, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI226371746, Length=388, Percent_Identity=26.8041237113402, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI226371748, Length=378, Percent_Identity=26.1904761904762, Blast_Score=80, Evalue=5e-15,
Organism=Escherichia coli, GI1789911, Length=492, Percent_Identity=28.6585365853659, Blast_Score=210, Evalue=2e-55,
Organism=Escherichia coli, GI1790572, Length=411, Percent_Identity=29.9270072992701, Blast_Score=195, Evalue=7e-51,
Organism=Escherichia coli, GI1786927, Length=417, Percent_Identity=30.9352517985612, Blast_Score=195, Evalue=7e-51,
Organism=Escherichia coli, GI1787922, Length=510, Percent_Identity=24.5098039215686, Blast_Score=184, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI71987453, Length=397, Percent_Identity=27.9596977329975, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17569141, Length=397, Percent_Identity=28.7153652392947, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17541704, Length=217, Percent_Identity=30.4147465437788, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24639585, Length=367, Percent_Identity=28.8828337874659, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24639583, Length=367, Percent_Identity=28.8828337874659, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24639581, Length=367, Percent_Identity=28.8828337874659, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI28571102, Length=408, Percent_Identity=25, Blast_Score=96, Evalue=7e-20,
Organism=Drosophila melanogaster, GI28571100, Length=408, Percent_Identity=25, Blast_Score=96, Evalue=7e-20,
Organism=Drosophila melanogaster, GI28571098, Length=408, Percent_Identity=25, Blast_Score=96, Evalue=8e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 54649; Mature: 54518

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: PS50850 MFS ; PS01022 PTR2_1 ; PS01023 PTR2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNHQKETFQNIPQKGFFGHPRGLFTLFFTEFWERFSYYGMRAILIYYLYTEVTKGGLGF
CCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DQTTANSIMAVYGSLVYMSGIIGGWIADRLLGTANTVFYGGVLIMFGHILLSFPGSVPAF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHH
FISMFLIIIGTGLLKPNVSSVVGDLYSPEDTRRDSGFSIFYMGINLGGFLAPIIVGTVGQ
HHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHCCC
TYNYHLGFSLAAIGMLFGLLTYLATRKKNLGSAGRTVPNPLTPAERKMVFGRIGIGVLVI
CEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
AAIFGYSIFMGWMTIKLFTMIVSCLGILIPLIYFIVMFKSSKTTSDERSRLTAYIPLFVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
SMMFWAIQEQGANILATYADKRTHLEFLGVQLHSSWFQSLNPLFIVVLAPVFAWIWMRLG
HHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHC
NRQPSTPTKFSLGLILAGLSFVVMIFPAYINGTESLANPMWLVLSFLIVVLGELCLSPVG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LSATSKLAPAAFSAQTMSLWFLSNASAQAINAQIVRFYSVDTEIAYFGIIGGVSILLGII
CCCHHHCCCCHHCHHHEEEEEECCCCHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHH
LMLLSPKIQKFMKGVN
HHHHCHHHHHHHCCCC
>Mature Secondary Structure 
SNHQKETFQNIPQKGFFGHPRGLFTLFFTEFWERFSYYGMRAILIYYLYTEVTKGGLGF
CCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DQTTANSIMAVYGSLVYMSGIIGGWIADRLLGTANTVFYGGVLIMFGHILLSFPGSVPAF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHH
FISMFLIIIGTGLLKPNVSSVVGDLYSPEDTRRDSGFSIFYMGINLGGFLAPIIVGTVGQ
HHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHCCC
TYNYHLGFSLAAIGMLFGLLTYLATRKKNLGSAGRTVPNPLTPAERKMVFGRIGIGVLVI
CEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
AAIFGYSIFMGWMTIKLFTMIVSCLGILIPLIYFIVMFKSSKTTSDERSRLTAYIPLFVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
SMMFWAIQEQGANILATYADKRTHLEFLGVQLHSSWFQSLNPLFIVVLAPVFAWIWMRLG
HHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHC
NRQPSTPTKFSLGLILAGLSFVVMIFPAYINGTESLANPMWLVLSFLIVVLGELCLSPVG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LSATSKLAPAAFSAQTMSLWFLSNASAQAINAQIVRFYSVDTEIAYFGIIGGVSILLGII
CCCHHHCCCCHHCHHHEEEEEECCCCHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHH
LMLLSPKIQKFMKGVN
HHHHCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]