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The map label for this gene is purR [H]

Identifier: 52783904

GI number: 52783904

Start: 58888

End: 59721

Strand: Direct

Name: purR [H]

Synonym: BLi00060

Alternate gene names: 52783904

Gene position: 58888-59721 (Clockwise)

Preceding gene: 52783903

Following gene: 52783905

Centisome position: 1.39

GC content: 46.04

Gene sequence:

>834_bases
ATGAAGTTTCGTCGAAGCGGCAGATTGGTGGATCTGACAAATTATTTGTTGACCCATCCGCATGTCTTAGTGCCATTAAC
CTTCTTTTCAGAACGGTATCAATCTGCTAAATCATCCATTAGTGAAGATTTAACCATCATTAAGCAGACCTTCGAGCAGC
AGGGAATCGGAACGCTTCAGACCGTGCCGGGAGCAGCCGGCGGCGTTAAATACATTCCAAAGGTAAAACGCGATGAAGCG
GAGGAATTTGTAAAGTCGCTCGGTGAGTCATTGATCGATTCGGAACGGATATTGCCCGGCGGATATTTGTATTTAACCGA
TATCCTTGGAAAGCCCTCTGTATTAACGAAGGCCGGCAAAATTTTTGCTTCCGCTTTTTCAGACAGGGAGATCGATGTCG
TGATGACGGTGGCGACAAAAGGCATTCCTTTGGCATATGCGGTAGCCAGCTACCTTGATGTGCCGACAGTGGTCGTCAGA
AAAGACAATAAGGTAACTGAAGGGTCAACGGTCAGCATCAACTATGTGTCCGGATCATCCAACCGCATTCAGACGATGTC
TCTTGCAAAACGAAGCTTGCAGACGGGCTCGCACGTTTTGATCATAGACGACTTTATGAAAGCGGGAGGAACGATCAACG
GCATGATCAATCTTCTCGATGAATTCAATGCCCATGTAGCGGGCATCGGTGTTCTTGTGGAAGCTCAGGGAGTCAAGGAG
CGGCTGGTCGATGAGTATATGTCCCTTTTGACTCTTTCTGAAATCGATATGAAGGAAAAAAAGGTGGAAATACAAAACGG
AAATTTTCAGCGTTTTTTTGCAGAAAATGAATAG

Upstream 100 bases:

>100_bases
TTTATGCGGTGCGGATGATCGGAGAACAAAATGAACTTGATTAAATCCGTATGTTAAGTTATATTGTTTTTAAAAATATT
CGGATTTTGGAGGTAAGTGC

Downstream 100 bases:

>100_bases
GAAATGGGGAGTTTGAGATGACAAAGGTTGTTCAGACAAAAGAAGCACCGGCGGCGATCGGACCGTATTCACAAGGAATT
GTTGTCAACAATATGTTTTA

Product: pur operon repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MKFRRSGRLVDLTNYLLTHPHVLVPLTFFSERYQSAKSSISEDLTIIKQTFEQQGIGTLQTVPGAAGGVKYIPKVKRDEA
EEFVKSLGESLIDSERILPGGYLYLTDILGKPSVLTKAGKIFASAFSDREIDVVMTVATKGIPLAYAVASYLDVPTVVVR
KDNKVTEGSTVSINYVSGSSNRIQTMSLAKRSLQTGSHVLIIDDFMKAGGTINGMINLLDEFNAHVAGIGVLVEAQGVKE
RLVDEYMSLLTLSEIDMKEKKVEIQNGNFQRFFAENE

Sequences:

>Translated_277_residues
MKFRRSGRLVDLTNYLLTHPHVLVPLTFFSERYQSAKSSISEDLTIIKQTFEQQGIGTLQTVPGAAGGVKYIPKVKRDEA
EEFVKSLGESLIDSERILPGGYLYLTDILGKPSVLTKAGKIFASAFSDREIDVVMTVATKGIPLAYAVASYLDVPTVVVR
KDNKVTEGSTVSINYVSGSSNRIQTMSLAKRSLQTGSHVLIIDDFMKAGGTINGMINLLDEFNAHVAGIGVLVEAQGVKE
RLVDEYMSLLTLSEIDMKEKKVEIQNGNFQRFFAENE
>Mature_277_residues
MKFRRSGRLVDLTNYLLTHPHVLVPLTFFSERYQSAKSSISEDLTIIKQTFEQQGIGTLQTVPGAAGGVKYIPKVKRDEA
EEFVKSLGESLIDSERILPGGYLYLTDILGKPSVLTKAGKIFASAFSDREIDVVMTVATKGIPLAYAVASYLDVPTVVVR
KDNKVTEGSTVSINYVSGSSNRIQTMSLAKRSLQTGSHVLIIDDFMKAGGTINGMINLLDEFNAHVAGIGVLVEAQGVKE
RLVDEYMSLLTLSEIDMKEKKVEIQNGNFQRFFAENE

Specific function: Controls the transcription of the pur operon for purine biosynthetic genes, binds to the control region of the operon. DNA binding is inhibited by 5-phosphoribosyl 1-pyrophosphate [H]

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR015265
- InterPro:   IPR010078
- InterPro:   IPR011991
- ProDom:   PD029816 [H]

Pfam domain/function: PF00156 Pribosyltran; PF09182 PuR_N [H]

EC number: NA

Molecular weight: Translated: 30475; Mature: 30475

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFRRSGRLVDLTNYLLTHPHVLVPLTFFSERYQSAKSSISEDLTIIKQTFEQQGIGTLQ
CCCCCCCCEEEHHHHHHHCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
TVPGAAGGVKYIPKVKRDEAEEFVKSLGESLIDSERILPGGYLYLTDILGKPSVLTKAGK
ECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHH
IFASAFSDREIDVVMTVATKGIPLAYAVASYLDVPTVVVRKDNKVTEGSTVSINYVSGSS
HHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEEEECCC
NRIQTMSLAKRSLQTGSHVLIIDDFMKAGGTINGMINLLDEFNAHVAGIGVLVEAQGVKE
CCHHHHHHHHHHHCCCCEEEEEEHHHHCCCCHHHHHHHHHHHCCCEEEEEEEEECCCHHH
RLVDEYMSLLTLSEIDMKEKKVEIQNGNFQRFFAENE
HHHHHHHHHHHHHHCCCHHHEEEECCCCEEEEEECCC
>Mature Secondary Structure
MKFRRSGRLVDLTNYLLTHPHVLVPLTFFSERYQSAKSSISEDLTIIKQTFEQQGIGTLQ
CCCCCCCCEEEHHHHHHHCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
TVPGAAGGVKYIPKVKRDEAEEFVKSLGESLIDSERILPGGYLYLTDILGKPSVLTKAGK
ECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHH
IFASAFSDREIDVVMTVATKGIPLAYAVASYLDVPTVVVRKDNKVTEGSTVSINYVSGSS
HHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEEEECCC
NRIQTMSLAKRSLQTGSHVLIIDDFMKAGGTINGMINLLDEFNAHVAGIGVLVEAQGVKE
CCHHHHHHHHHHHCCCCEEEEEEHHHHCCCCHHHHHHHHHHHCCCEEEEEEEEECCCHHH
RLVDEYMSLLTLSEIDMKEKKVEIQNGNFQRFFAENE
HHHHHHHHHHHHHHCCCHHHEEEECCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 7638212 [H]