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The map label for this gene is galE [H]

Identifier: 52145257

GI number: 52145257

Start: 5260905

End: 5261921

Strand: Reverse

Name: galE [H]

Synonym: BCZK5146

Alternate gene names: 52145257

Gene position: 5261921-5260905 (Counterclockwise)

Preceding gene: 52145258

Following gene: 52145255

Centisome position: 99.26

GC content: 34.71

Gene sequence:

>1017_bases
ATGGCGATACTTATAACGGGTGGAGCAGGGTATATTGGTAGTCATACATGTGTAGAATTATTAAATAATAATTATAAAAT
TATAGTCGTAGATAATCTTTCAAATAGTTCAATTGAATCTTTAAATCGAGTAAAAGAAATAACAGGAAAACAATTTGAAT
TTTATAAAGAAAATGTTTTAAATCGTGAAAAAATGAATGAGATCTTTTTGGAAAATAACATTGAAGCGGTTATACATTTT
GCGGGGTTTAAAGCAGTGGGAGAATCTACCACAATACCACTTACATATTATTATAACAATATAATAAGTGCAATTGTACT
ATGTGATGTGATGCAAAAACACAATGTTAAAAATTTTATTTTTAGTTCATCTGCAACTGTATATGGAATTCCAAAAACAT
CACCAATTACAGAAGAATTTCCGCTGAGTGTGACAAATCCGTATGGACAAACAAAATTAATGATTGAGCAAATTATGCGT
GATGTAGCAAAGGCTGATGATGAGTGGAGTATTGCATTACTTCGTTATTTTAATCCATTTGGAGCTCATCAAAGTGGCCG
TATCGGAGAAGATCCAAATGGGATTCCGAACAATTTAATGCCATATGTAACGCAAGTAGCGGTAGGTAAGTTAAAGGAGC
TAAATATATTCGGAAACGATTATCCAACGAAAGATGGGACGGGTGTCCGTGATTATATTCACGTTGTTGACCTTGCGAAG
GGACATGTAAAGGCACTTGAGAAAGTACTTAAGACGAAAGGAATCGAGGCATATAATCTTGGCACAGGTAAAGGGTATAG
TGTATTGGAGATGGTAAAGGCTTTTGAGAAGGTTTCGGGTAAAAAAATACCTTATAAAGTGATAGGGCGTCGTCCTGGTG
ATGTAGCAATCTGTTTTGCGGATGTATCTAAAGCGAAACGAGAATTAGGATGGGAAGCGGAATATGGGTTAGAAGAGATG
TGTGTAGATTCTTGGAGATGGCAAGTAAATAATAAAAATGGCTATCAAATGATTTAG

Upstream 100 bases:

>100_bases
CGGGGATAATTTTTAGAATTATCAGTCCTTTTGGCGGTAAGATAGATGTGCATTGAGATTATAAAATTTTATAATTAATA
ATTAGTGGGGGACTATAGAT

Downstream 100 bases:

>100_bases
GGTAGCTAGTAAAGCATGCTCTTATTATTTTATGTATACAATGAATTGTAATCTTTATTATGTTGCATGAGATCAGTAAT
ATGTTCACTTTAGGAAAGAG

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MAILITGGAGYIGSHTCVELLNNNYKIIVVDNLSNSSIESLNRVKEITGKQFEFYKENVLNREKMNEIFLENNIEAVIHF
AGFKAVGESTTIPLTYYYNNIISAIVLCDVMQKHNVKNFIFSSSATVYGIPKTSPITEEFPLSVTNPYGQTKLMIEQIMR
DVAKADDEWSIALLRYFNPFGAHQSGRIGEDPNGIPNNLMPYVTQVAVGKLKELNIFGNDYPTKDGTGVRDYIHVVDLAK
GHVKALEKVLKTKGIEAYNLGTGKGYSVLEMVKAFEKVSGKKIPYKVIGRRPGDVAICFADVSKAKRELGWEAEYGLEEM
CVDSWRWQVNNKNGYQMI

Sequences:

>Translated_338_residues
MAILITGGAGYIGSHTCVELLNNNYKIIVVDNLSNSSIESLNRVKEITGKQFEFYKENVLNREKMNEIFLENNIEAVIHF
AGFKAVGESTTIPLTYYYNNIISAIVLCDVMQKHNVKNFIFSSSATVYGIPKTSPITEEFPLSVTNPYGQTKLMIEQIMR
DVAKADDEWSIALLRYFNPFGAHQSGRIGEDPNGIPNNLMPYVTQVAVGKLKELNIFGNDYPTKDGTGVRDYIHVVDLAK
GHVKALEKVLKTKGIEAYNLGTGKGYSVLEMVKAFEKVSGKKIPYKVIGRRPGDVAICFADVSKAKRELGWEAEYGLEEM
CVDSWRWQVNNKNGYQMI
>Mature_337_residues
AILITGGAGYIGSHTCVELLNNNYKIIVVDNLSNSSIESLNRVKEITGKQFEFYKENVLNREKMNEIFLENNIEAVIHFA
GFKAVGESTTIPLTYYYNNIISAIVLCDVMQKHNVKNFIFSSSATVYGIPKTSPITEEFPLSVTNPYGQTKLMIEQIMRD
VAKADDEWSIALLRYFNPFGAHQSGRIGEDPNGIPNNLMPYVTQVAVGKLKELNIFGNDYPTKDGTGVRDYIHVVDLAKG
HVKALEKVLKTKGIEAYNLGTGKGYSVLEMVKAFEKVSGKKIPYKVIGRRPGDVAICFADVSKAKRELGWEAEYGLEEMC
VDSWRWQVNNKNGYQMI

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=340, Percent_Identity=57.6470588235294, Blast_Score=411, Evalue=1e-115,
Organism=Homo sapiens, GI56118217, Length=340, Percent_Identity=57.6470588235294, Blast_Score=411, Evalue=1e-115,
Organism=Homo sapiens, GI189083684, Length=340, Percent_Identity=57.6470588235294, Blast_Score=411, Evalue=1e-115,
Organism=Homo sapiens, GI7657641, Length=274, Percent_Identity=26.6423357664234, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI42516563, Length=332, Percent_Identity=23.4939759036145, Blast_Score=76, Evalue=4e-14,
Organism=Escherichia coli, GI1786974, Length=336, Percent_Identity=55.0595238095238, Blast_Score=383, Evalue=1e-108,
Organism=Escherichia coli, GI48994969, Length=362, Percent_Identity=25.1381215469613, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1788353, Length=364, Percent_Identity=26.9230769230769, Blast_Score=90, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71982035, Length=345, Percent_Identity=55.3623188405797, Blast_Score=393, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI71982038, Length=347, Percent_Identity=55.043227665706, Blast_Score=392, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI17568069, Length=336, Percent_Identity=26.7857142857143, Blast_Score=81, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6319493, Length=344, Percent_Identity=54.0697674418605, Blast_Score=379, Evalue=1e-106,
Organism=Drosophila melanogaster, GI19923002, Length=342, Percent_Identity=57.6023391812866, Blast_Score=421, Evalue=1e-118,
Organism=Drosophila melanogaster, GI21356223, Length=321, Percent_Identity=22.7414330218069, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040
- InterPro:   IPR008089 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 37862; Mature: 37731

Theoretical pI: Translated: 7.53; Mature: 7.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILITGGAGYIGSHTCVELLNNNYKIIVVDNLSNSSIESLNRVKEITGKQFEFYKENVL
CEEEEECCCCCCCHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHC
NREKMNEIFLENNIEAVIHFAGFKAVGESTTIPLTYYYNNIISAIVLCDVMQKHNVKNFI
CHHHHHHHHHCCCCEEEEEECCHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCHHHHE
FSSSATVYGIPKTSPITEEFPLSVTNPYGQTKLMIEQIMRDVAKADDEWSIALLRYFNPF
EECCCEEEECCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHCCCCCCEEHHHHHCCCC
GAHQSGRIGEDPNGIPNNLMPYVTQVAVGKLKELNIFGNDYPTKDGTGVRDYIHVVDLAK
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCHHEEEEECCCCCCCCCCCHHHHHHHHHHHH
GHVKALEKVLKTKGIEAYNLGTGKGYSVLEMVKAFEKVSGKKIPYKVIGRRPGDVAICFA
HHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHCCCCCCHHEECCCCCCEEEEEH
DVSKAKRELGWEAEYGLEEMCVDSWRWQVNNKNGYQMI
HHHHHHHHCCCCHHCCHHHHHHHHHEEEECCCCCCCCC
>Mature Secondary Structure 
AILITGGAGYIGSHTCVELLNNNYKIIVVDNLSNSSIESLNRVKEITGKQFEFYKENVL
EEEEECCCCCCCHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHC
NREKMNEIFLENNIEAVIHFAGFKAVGESTTIPLTYYYNNIISAIVLCDVMQKHNVKNFI
CHHHHHHHHHCCCCEEEEEECCHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCHHHHE
FSSSATVYGIPKTSPITEEFPLSVTNPYGQTKLMIEQIMRDVAKADDEWSIALLRYFNPF
EECCCEEEECCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHCCCCCCEEHHHHHCCCC
GAHQSGRIGEDPNGIPNNLMPYVTQVAVGKLKELNIFGNDYPTKDGTGVRDYIHVVDLAK
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCHHEEEEECCCCCCCCCCCHHHHHHHHHHHH
GHVKALEKVLKTKGIEAYNLGTGKGYSVLEMVKAFEKVSGKKIPYKVIGRRPGDVAICFA
HHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHCCCCCCHHEECCCCCCEEEEEH
DVSKAKRELGWEAEYGLEEMCVDSWRWQVNNKNGYQMI
HHHHHHHHCCCCHHCCHHHHHHHHHEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8978088; 8969509; 9384377 [H]