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The map label for this gene is ykhA [H]

Identifier: 52145234

GI number: 52145234

Start: 5232608

End: 5233120

Strand: Direct

Name: ykhA [H]

Synonym: BCZK5122

Alternate gene names: 52145234

Gene position: 5232608-5233120 (Clockwise)

Preceding gene: 52145232

Following gene: 52145235

Centisome position: 98.71

GC content: 36.65

Gene sequence:

>513_bases
ATGGAAAAGAAATTCATGCGAGAATCTAAAGCAATTAAAACAACACGTGTTTTTCCGAATGATTTAAATAATCATCAAAC
ACTTTTCGGAGGAAAATTATTAGCGGAAATTGATAGTATCGCTTCAATTGCAGCTGCAAGGCATAGTCGTAAACATTGCG
TAACAGCATCTATCGATTCTGTTGATTTTTTAACTCCCATTCACCAAGCAGATTCTGTTTGTTACGAAGCATTCGTATGT
TATACAGGAAAATCTTCAATGGAAGTGTTCGTAAAAGTAATTGCAGAGAATTTATTAGCAGGAGAACGTAGAATAGCTGC
AACATGTTTCATTACATTCGTTGCATTAAAAGATGGAAAACCTTCTTCTGTTCCACAAGTACTGCCTGAAACGGAAGAAG
AACATTGGCTACACACAACTGGTGCTGAGCGTGCAGAAAGCAGAAAAAAAGGGCGTGTAAAAAGCAAAGAAATGGCTGAA
GTTCTAACTTTAAGTAAACCTTGGAGTATGTAG

Upstream 100 bases:

>100_bases
ATTCTTTACTTCATTAAATATCTATTGATTTTTAATAACTTTGTACTCCACTTACAACACATGTCATTCTGATCGAAAAC
AGAAAATAGGGGCTGACCAT

Downstream 100 bases:

>100_bases
AGACCTTCACCGTTAAGAAATCTTCCGAGCGAATAACGATCATGTATTCGCTCATTTTTTATAAACAATTTCCCACCTTC
ATACAACCATTCCTCCTTTT

Product: acyl-CoA hydrolase (cytosolic long-chain acyl-CoA thioester hydrolase)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 170; Mature: 170

Protein sequence:

>170_residues
MEKKFMRESKAIKTTRVFPNDLNNHQTLFGGKLLAEIDSIASIAAARHSRKHCVTASIDSVDFLTPIHQADSVCYEAFVC
YTGKSSMEVFVKVIAENLLAGERRIAATCFITFVALKDGKPSSVPQVLPETEEEHWLHTTGAERAESRKKGRVKSKEMAE
VLTLSKPWSM

Sequences:

>Translated_170_residues
MEKKFMRESKAIKTTRVFPNDLNNHQTLFGGKLLAEIDSIASIAAARHSRKHCVTASIDSVDFLTPIHQADSVCYEAFVC
YTGKSSMEVFVKVIAENLLAGERRIAATCFITFVALKDGKPSSVPQVLPETEEEHWLHTTGAERAESRKKGRVKSKEMAE
VLTLSKPWSM
>Mature_170_residues
MEKKFMRESKAIKTTRVFPNDLNNHQTLFGGKLLAEIDSIASIAAARHSRKHCVTASIDSVDFLTPIHQADSVCYEAFVC
YTGKSSMEVFVKVIAENLLAGERRIAATCFITFVALKDGKPSSVPQVLPETEEEHWLHTTGAERAESRKKGRVKSKEMAE
VLTLSKPWSM

Specific function: Unknown

COG id: COG1607

COG function: function code I; Acyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl coenzyme A hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI32528286, Length=121, Percent_Identity=35.5371900826446, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI32528284, Length=121, Percent_Identity=35.5371900826446, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI75709208, Length=121, Percent_Identity=35.5371900826446, Blast_Score=76, Evalue=1e-14,
Organism=Homo sapiens, GI32528282, Length=121, Percent_Identity=35.5371900826446, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI22165355, Length=132, Percent_Identity=35.6060606060606, Blast_Score=71, Evalue=5e-13,
Organism=Homo sapiens, GI22165400, Length=132, Percent_Identity=35.6060606060606, Blast_Score=70, Evalue=6e-13,
Organism=Homo sapiens, GI18640736, Length=122, Percent_Identity=34.4262295081967, Blast_Score=67, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006683 [H]

Pfam domain/function: PF03061 4HBT [H]

EC number: 3.1.2.- [C]

Molecular weight: Translated: 18957; Mature: 18957

Theoretical pI: Translated: 8.65; Mature: 8.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKKFMRESKAIKTTRVFPNDLNNHQTLFGGKLLAEIDSIASIAAARHSRKHCVTASIDS
CCHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCC
VDFLTPIHQADSVCYEAFVCYTGKSSMEVFVKVIAENLLAGERRIAATCFITFVALKDGK
HHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHEEECCCC
PSSVPQVLPETEEEHWLHTTGAERAESRKKGRVKSKEMAEVLTLSKPWSM
CCCCCCCCCCCCCCCEEECCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MEKKFMRESKAIKTTRVFPNDLNNHQTLFGGKLLAEIDSIASIAAARHSRKHCVTASIDS
CCHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCC
VDFLTPIHQADSVCYEAFVCYTGKSSMEVFVKVIAENLLAGERRIAATCFITFVALKDGK
HHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHEEECCCC
PSSVPQVLPETEEEHWLHTTGAERAESRKKGRVKSKEMAEVLTLSKPWSM
CCCCCCCCCCCCCCCEEECCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds; Thiolester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8682784; 9384377; 10568751 [H]