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The map label for this gene is nsr [H]

Identifier: 52145218

GI number: 52145218

Start: 5214319

End: 5214990

Strand: Direct

Name: nsr [H]

Synonym: BCZK5106

Alternate gene names: 52145218

Gene position: 5214319-5214990 (Clockwise)

Preceding gene: 52145213

Following gene: 52145222

Centisome position: 98.37

GC content: 32.44

Gene sequence:

>672_bases
ATGAAAGTCAGTAAAAATAGCGAAGAAATCTCTCATTACATACAAACTTACAACTTCCATACTCTTTTTTCTTTTGACAT
TTTACCGTATGCTGAACTACATTCCTTTCAGAAGAGAGAAAAGATATGTAATGAAGGGGTTGATGTTCCTTATCTCTATT
ACTTAATTTCCGGGAAAGCAAAAATATATATGAGTCACAAAAACGGAAAGGTCTCCTTAATTAACTTTATTCAAGCACCT
TCGTTCATTGGGGAATTAGGATTAATTGGCGTAGAATCCGTCACGAAAACGGTGGAAGTAATGGAAGATTGTATATGCTT
AGCGCTTCCTCTTAAAGATTGTCAGCATATTTTATTACAAGATGCTATCTTTCTGCAGAAACTATGCAAATTTATCGGTG
AAAAAACAATTACCCGAACAGAAAGTTATGCTAAAAATAATAGTTATCCGTTCGAAAATCGATTAGCAGCGTTTATTCTA
TTAACAGAACAAAATAACAGTTATACAGAAAAACATACCGAGGCTTCGGAATATTTAAATGTTAGCTATCGTCACCTTTT
ATACGTATTAAATCAGTTTTGCCAACAAAATTACTTAAAGAAAGATGGAAGAACCTATTACATACAAGATCGCAATCAAC
TAGAAAAACTTGCTGATGAGCTAAAAATATAA

Upstream 100 bases:

>100_bases
CTCACACTCTCTTTTCTACAAAAACAAATTTACGTAAATCGTAGCATTCTTTCTTGTAAAAATAATAGGAGATATCTCAT
ACTAAACATGAGGTGAAAAC

Downstream 100 bases:

>100_bases
AGAAACAGCATTAACATAAACGTTAATGCTGTTTCTTTGAGTGACGATTATAATTTCAATTAAAATTTATTTGCTACTTT
AGCTGCTTCTTCAAGACCAG

Product: DNA-binding transcriptional activator YeiL

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MKVSKNSEEISHYIQTYNFHTLFSFDILPYAELHSFQKREKICNEGVDVPYLYYLISGKAKIYMSHKNGKVSLINFIQAP
SFIGELGLIGVESVTKTVEVMEDCICLALPLKDCQHILLQDAIFLQKLCKFIGEKTITRTESYAKNNSYPFENRLAAFIL
LTEQNNSYTEKHTEASEYLNVSYRHLLYVLNQFCQQNYLKKDGRTYYIQDRNQLEKLADELKI

Sequences:

>Translated_223_residues
MKVSKNSEEISHYIQTYNFHTLFSFDILPYAELHSFQKREKICNEGVDVPYLYYLISGKAKIYMSHKNGKVSLINFIQAP
SFIGELGLIGVESVTKTVEVMEDCICLALPLKDCQHILLQDAIFLQKLCKFIGEKTITRTESYAKNNSYPFENRLAAFIL
LTEQNNSYTEKHTEASEYLNVSYRHLLYVLNQFCQQNYLKKDGRTYYIQDRNQLEKLADELKI
>Mature_223_residues
MKVSKNSEEISHYIQTYNFHTLFSFDILPYAELHSFQKREKICNEGVDVPYLYYLISGKAKIYMSHKNGKVSLINFIQAP
SFIGELGLIGVESVTKTVEVMEDCICLALPLKDCQHILLQDAIFLQKLCKFIGEKTITRTESYAKNNSYPFENRLAAFIL
LTEQNNSYTEKHTEASEYLNVSYRHLLYVLNQFCQQNYLKKDGRTYYIQDRNQLEKLADELKI

Specific function: Transcription regulator involved in mid-term, stationary-phase viability under nitrogen starvation. Might control expression of the salvage pathways or in some other way repress the recycling of nucleobases to nucleic acids and enhance their use as genera

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788487, Length=203, Percent_Identity=45.320197044335, Blast_Score=181, Evalue=5e-47,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR012318
- InterPro:   IPR014710 [H]

Pfam domain/function: PF00027 cNMP_binding [H]

EC number: NA

Molecular weight: Translated: 26014; Mature: 26014

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: PS50042 CNMP_BINDING_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVSKNSEEISHYIQTYNFHTLFSFDILPYAELHSFQKREKICNEGVDVPYLYYLISGKA
CCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCE
KIYMSHKNGKVSLINFIQAPSFIGELGLIGVESVTKTVEVMEDCICLALPLKDCQHILLQ
EEEEECCCCCEEEHHHHHCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
DAIFLQKLCKFIGEKTITRTESYAKNNSYPFENRLAAFILLTEQNNSYTEKHTEASEYLN
HHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHCEEEEEEEECCCCCCHHHHHHHHHHHH
VSYRHLLYVLNQFCQQNYLKKDGRTYYIQDRNQLEKLADELKI
HHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHCC
>Mature Secondary Structure
MKVSKNSEEISHYIQTYNFHTLFSFDILPYAELHSFQKREKICNEGVDVPYLYYLISGKA
CCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCE
KIYMSHKNGKVSLINFIQAPSFIGELGLIGVESVTKTVEVMEDCICLALPLKDCQHILLQ
EEEEECCCCCEEEHHHHHCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
DAIFLQKLCKFIGEKTITRTESYAKNNSYPFENRLAAFILLTEQNNSYTEKHTEASEYLN
HHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHCEEEEEEEECCCCCCHHHHHHHHHHHH
VSYRHLLYVLNQFCQQNYLKKDGRTYYIQDRNQLEKLADELKI
HHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]