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The map label for this gene is cpdC [H]

Identifier: 52142978

GI number: 52142978

Start: 2391332

End: 2393347

Strand: Direct

Name: cpdC [H]

Synonym: BCZK2261

Alternate gene names: 52142978

Gene position: 2391332-2393347 (Clockwise)

Preceding gene: 52142981

Following gene: 52142975

Centisome position: 45.11

GC content: 35.17

Gene sequence:

>2016_bases
ATGACAGTACAAAAGGGGAGAAATATTGTTATTATGCAAAAAATGAAATGGAAGAACTATTTATGTTATTTTGTTATTCT
TATACTTCTTGGAACAGCAGTAACAGTCAAACCATCTATCTCGAAAGCTGAGGAATCTGATGTTAATATTACACTGTTAG
GTACTGCAGATATTCATGGTAGATTTATGCCTTGGGATTATGCGCTTGATGGTGCAAATACGAGTGGAAGTTTAACGCAG
CTTTATACGGCTATAAAGAAGGTACGTCAAGAAAATCCAAATACCATATTAGTAGATGCTGGGGATACAATTCAAGGAAA
TTCAGTAGAGTTATTCAATGATCAGCCACAATCGCCAATGATGGTAGCGATGAATGCAATGGGATATGATGCTTGGGCAT
TTGGAAATCATGAGTTTAACTTTGGATTAGATACGTTGAAAAAAGTTAGTGAGCAATATAAGGGCAAGACATTGGCAGGA
AATATTTATAAGGAAAATGGAGAGCGTTTTCTTCCTGCATATACAATTGTTGAAAAAGGTGGAATTAAAGTCGGAATTAT
TGGTATGAATACACCAATGATTAGTGATTTTGAAAAAGGGACAGATCATTTGGATGGATTGGTAGTGAAAAATCCAGTAG
AAGAAACAAAAAAGGCAATTAAAGAATTAGAGGGTAAAGTAGATGTAATGGTAGGGGTTATGCATATGGGACTAGAAAAT
GAGAATGGAATCTCTGGTACTGGTGTTCAAGATATTGCGAATGCTTGTCCGGAACTAAGTGCTATTTTTGCAGCTCATAT
GCATAAACTTGTTAAAAAAGAAGTTGTAAATGGCGTTATTATTACAGAACCAGATAAATATGGAACACATATCTCGCGTA
TTGATCTTACTTTTACAAAGCAAGATGGAAAGCTGGTTCTAAAAGATAAAACTGCTACAGCTATACCTGTAAAAAATACT
GATGGAACAACAGTAGTATCTGATTCTACACTTGAAGACACACTGATGCCTTTTCACGAGTATGCGAGGGGTGATGCAAA
TGTTGTAGTCGCTCAATTAAAGGGTAGAAACCTTGTTCCTGAAAATGAAATAAAGGGTATTCCAAGTGTGCAGATTCAAG
AGACACCTTTATCAGATTTCTTTCATGAGGTCATGCTCTATTACAGCAAAGCAGATGTAGTCGCCCATCAAATTGATAAC
GATAAAGCTCGTTTGGATGTAGGGCCTATAAAGAAAAAAGATATTGCGTATAATTATCAATATGCTCTGGGAGAAATTAC
GGTATATAAGGTAACTGGGAAAGACTTAAAAGACTATATGGAATGGGCGGCAGGGTACTTTAACTCATCTCGTGCTGGAG
ATGTAACAGTTAGCTTTGATAAAACCCGTCGTGCTTCGAAATACAGTACGAACGATTTCTTTGGAGGCGTAAAATACGAA
ATTGACTTAACAAAACCATATGGAAGTAGAATTACAAATTTACGTTCTATTCGTACAAATAAACCAATTAAAACGAACGA
TGTTATGACGCTGGGAATGAATGCATATAGAATGGAGGCTCTTCAGGCAAAAGGTGGAGCTTTAGAGGGGCGTAAGTTTG
AACAAATTTGGTCATCTAAACAAGAGAATGCATTCGGGGAAACAGGTGGAACCATTCGTAACCTTGCTATTACATATTTA
AAAGAGGTGAAGAACGGTGTTTACACACCAAAAGTTATGCATAATTGGAAAATTACTGGCGTGAATACACATTCTTCAGA
GCATAAGGCTGTAGTAGATCTTGTGAATAAAGGGATTTTAGAAATTCCAAAAACTGAAGATGGAAAATATACAAACATAG
CATCTATAAATACTAAAGATTCAATTACAAAAGAGGAAATTGTCGCACTCTCACAAAAAGTAAATATTAATCCAAATCAG
TTTAAGCATATAAAAACGAAAGGCGAATTTTACAAAAAACTTAGTAGAATTGTAAAAAAATATAAGAAACATGACTCTAG
TGCAAAAAAGTTATAA

Upstream 100 bases:

>100_bases
ATATGCACTTTATTTTCATAAAAGAATCACCCGCTAAATTTCTTTTTGTAGTTGAAGTTTTCCGAATAATAAGTTACATT
TTTAAAGTTCAAGCAACTAT

Downstream 100 bases:

>100_bases
CTAGAAGTTTAAATATATACGCAAAAAAGAGCACTCCTATACATGGCGATAGGATGCTCTTTTTTATGTTAAGAAAATCT
TGTCTACTTTTAGTCTATCA

Product: 2',3'-cyclic-nucleotide 2'-phosphodiesterase

Products: NA

Alternate protein names: 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase; 5'-nucleotidase [H]

Number of amino acids: Translated: 671; Mature: 670

Protein sequence:

>671_residues
MTVQKGRNIVIMQKMKWKNYLCYFVILILLGTAVTVKPSISKAEESDVNITLLGTADIHGRFMPWDYALDGANTSGSLTQ
LYTAIKKVRQENPNTILVDAGDTIQGNSVELFNDQPQSPMMVAMNAMGYDAWAFGNHEFNFGLDTLKKVSEQYKGKTLAG
NIYKENGERFLPAYTIVEKGGIKVGIIGMNTPMISDFEKGTDHLDGLVVKNPVEETKKAIKELEGKVDVMVGVMHMGLEN
ENGISGTGVQDIANACPELSAIFAAHMHKLVKKEVVNGVIITEPDKYGTHISRIDLTFTKQDGKLVLKDKTATAIPVKNT
DGTTVVSDSTLEDTLMPFHEYARGDANVVVAQLKGRNLVPENEIKGIPSVQIQETPLSDFFHEVMLYYSKADVVAHQIDN
DKARLDVGPIKKKDIAYNYQYALGEITVYKVTGKDLKDYMEWAAGYFNSSRAGDVTVSFDKTRRASKYSTNDFFGGVKYE
IDLTKPYGSRITNLRSIRTNKPIKTNDVMTLGMNAYRMEALQAKGGALEGRKFEQIWSSKQENAFGETGGTIRNLAITYL
KEVKNGVYTPKVMHNWKITGVNTHSSEHKAVVDLVNKGILEIPKTEDGKYTNIASINTKDSITKEEIVALSQKVNINPNQ
FKHIKTKGEFYKKLSRIVKKYKKHDSSAKKL

Sequences:

>Translated_671_residues
MTVQKGRNIVIMQKMKWKNYLCYFVILILLGTAVTVKPSISKAEESDVNITLLGTADIHGRFMPWDYALDGANTSGSLTQ
LYTAIKKVRQENPNTILVDAGDTIQGNSVELFNDQPQSPMMVAMNAMGYDAWAFGNHEFNFGLDTLKKVSEQYKGKTLAG
NIYKENGERFLPAYTIVEKGGIKVGIIGMNTPMISDFEKGTDHLDGLVVKNPVEETKKAIKELEGKVDVMVGVMHMGLEN
ENGISGTGVQDIANACPELSAIFAAHMHKLVKKEVVNGVIITEPDKYGTHISRIDLTFTKQDGKLVLKDKTATAIPVKNT
DGTTVVSDSTLEDTLMPFHEYARGDANVVVAQLKGRNLVPENEIKGIPSVQIQETPLSDFFHEVMLYYSKADVVAHQIDN
DKARLDVGPIKKKDIAYNYQYALGEITVYKVTGKDLKDYMEWAAGYFNSSRAGDVTVSFDKTRRASKYSTNDFFGGVKYE
IDLTKPYGSRITNLRSIRTNKPIKTNDVMTLGMNAYRMEALQAKGGALEGRKFEQIWSSKQENAFGETGGTIRNLAITYL
KEVKNGVYTPKVMHNWKITGVNTHSSEHKAVVDLVNKGILEIPKTEDGKYTNIASINTKDSITKEEIVALSQKVNINPNQ
FKHIKTKGEFYKKLSRIVKKYKKHDSSAKKL
>Mature_670_residues
TVQKGRNIVIMQKMKWKNYLCYFVILILLGTAVTVKPSISKAEESDVNITLLGTADIHGRFMPWDYALDGANTSGSLTQL
YTAIKKVRQENPNTILVDAGDTIQGNSVELFNDQPQSPMMVAMNAMGYDAWAFGNHEFNFGLDTLKKVSEQYKGKTLAGN
IYKENGERFLPAYTIVEKGGIKVGIIGMNTPMISDFEKGTDHLDGLVVKNPVEETKKAIKELEGKVDVMVGVMHMGLENE
NGISGTGVQDIANACPELSAIFAAHMHKLVKKEVVNGVIITEPDKYGTHISRIDLTFTKQDGKLVLKDKTATAIPVKNTD
GTTVVSDSTLEDTLMPFHEYARGDANVVVAQLKGRNLVPENEIKGIPSVQIQETPLSDFFHEVMLYYSKADVVAHQIDND
KARLDVGPIKKKDIAYNYQYALGEITVYKVTGKDLKDYMEWAAGYFNSSRAGDVTVSFDKTRRASKYSTNDFFGGVKYEI
DLTKPYGSRITNLRSIRTNKPIKTNDVMTLGMNAYRMEALQAKGGALEGRKFEQIWSSKQENAFGETGGTIRNLAITYLK
EVKNGVYTPKVMHNWKITGVNTHSSEHKAVVDLVNKGILEIPKTEDGKYTNIASINTKDSITKEEIVALSQKVNINPNQF
KHIKTKGEFYKKLSRIVKKYKKHDSSAKKL

Specific function: Catalyzes the release of inorganic phosphate from 2',3'- cyclic nucleotides through consecutive 2',3'-phosphodiesterase and 3'- (or 2') nucleotidase activities. Also possesses a 5'- nucleotidase activity. Does not catalyze the release of inorganic phospha

COG id: COG0737

COG function: function code F; 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5'-nucleotidase family [H]

Homologues:

Organism=Homo sapiens, GI4505467, Length=234, Percent_Identity=27.7777777777778, Blast_Score=73, Evalue=1e-12,
Organism=Escherichia coli, GI1790658, Length=612, Percent_Identity=25, Blast_Score=129, Evalue=7e-31,
Organism=Escherichia coli, GI1786687, Length=457, Percent_Identity=25.8205689277899, Blast_Score=102, Evalue=1e-22,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008334
- InterPro:   IPR006146
- InterPro:   IPR006179
- InterPro:   IPR019931
- InterPro:   IPR004843
- InterPro:   IPR001899 [H]

Pfam domain/function: PF02872 5_nucleotid_C; PF00149 Metallophos [H]

EC number: =3.1.3.6; =3.1.4.16; =3.1.3.5 [H]

Molecular weight: Translated: 74697; Mature: 74565

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVQKGRNIVIMQKMKWKNYLCYFVILILLGTAVTVKPSISKAEESDVNITLLGTADIHG
CCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCEEEEEEECCCCC
RFMPWDYALDGANTSGSLTQLYTAIKKVRQENPNTILVDAGDTIQGNSVELFNDQPQSPM
CCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEECCCCCCCE
MVAMNAMGYDAWAFGNHEFNFGLDTLKKVSEQYKGKTLAGNIYKENGERFLPAYTIVEKG
EEEEECCCCCEEEECCCEECCCHHHHHHHHHHHCCCEEECCCCCCCCCEECCEEEEEECC
GIKVGIIGMNTPMISDFEKGTDHLDGLVVKNPVEETKKAIKELEGKVDVMVGVMHMGLEN
CEEEEEEECCCCCCCCHHCCCHHHCCEEECCCHHHHHHHHHHHCCCHHHEEEHHHHCCCC
ENGISGTGVQDIANACPELSAIFAAHMHKLVKKEVVNGVIITEPDKYGTHISRIDLTFTK
CCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCEEEECCHHHCCEEEEEEEEEEE
QDGKLVLKDKTATAIPVKNTDGTTVVSDSTLEDTLMPFHEYARGDANVVVAQLKGRNLVP
CCCEEEEECCCCEEEEEECCCCCEEEECCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCC
ENEIKGIPSVQIQETPLSDFFHEVMLYYSKADVVAHQIDNDKARLDVGPIKKKDIAYNYQ
HHHCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEEE
YALGEITVYKVTGKDLKDYMEWAAGYFNSSRAGDVTVSFDKTRRASKYSTNDFFGGVKYE
EEECEEEEEEECCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEE
IDLTKPYGSRITNLRSIRTNKPIKTNDVMTLGMNAYRMEALQAKGGALEGRKFEQIWSSK
EEECCCCCHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHCCCCCCCCCHHHHHHCCC
QENAFGETGGTIRNLAITYLKEVKNGVYTPKVMHNWKITGVNTHSSEHKAVVDLVNKGIL
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECEEEEEECCCCCCHHHHHHHHHCCCE
EIPKTEDGKYTNIASINTKDSITKEEIVALSQKVNINPNQFKHIKTKGEFYKKLSRIVKK
ECCCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCHHHHHEECCHHHHHHHHHHHHHH
YKKHDSSAKKL
HHHCCCHHCCC
>Mature Secondary Structure 
TVQKGRNIVIMQKMKWKNYLCYFVILILLGTAVTVKPSISKAEESDVNITLLGTADIHG
CCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCEEEEEEECCCCC
RFMPWDYALDGANTSGSLTQLYTAIKKVRQENPNTILVDAGDTIQGNSVELFNDQPQSPM
CCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEECCCCCCCE
MVAMNAMGYDAWAFGNHEFNFGLDTLKKVSEQYKGKTLAGNIYKENGERFLPAYTIVEKG
EEEEECCCCCEEEECCCEECCCHHHHHHHHHHHCCCEEECCCCCCCCCEECCEEEEEECC
GIKVGIIGMNTPMISDFEKGTDHLDGLVVKNPVEETKKAIKELEGKVDVMVGVMHMGLEN
CEEEEEEECCCCCCCCHHCCCHHHCCEEECCCHHHHHHHHHHHCCCHHHEEEHHHHCCCC
ENGISGTGVQDIANACPELSAIFAAHMHKLVKKEVVNGVIITEPDKYGTHISRIDLTFTK
CCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCEEEECCHHHCCEEEEEEEEEEE
QDGKLVLKDKTATAIPVKNTDGTTVVSDSTLEDTLMPFHEYARGDANVVVAQLKGRNLVP
CCCEEEEECCCCEEEEEECCCCCEEEECCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCC
ENEIKGIPSVQIQETPLSDFFHEVMLYYSKADVVAHQIDNDKARLDVGPIKKKDIAYNYQ
HHHCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEEE
YALGEITVYKVTGKDLKDYMEWAAGYFNSSRAGDVTVSFDKTRRASKYSTNDFFGGVKYE
EEECEEEEEEECCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEE
IDLTKPYGSRITNLRSIRTNKPIKTNDVMTLGMNAYRMEALQAKGGALEGRKFEQIWSSK
EEECCCCCHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHCCCCCCCCCHHHHHHCCC
QENAFGETGGTIRNLAITYLKEVKNGVYTPKVMHNWKITGVNTHSSEHKAVVDLVNKGIL
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECEEEEEECCCCCCHHHHHHHHHCCCE
EIPKTEDGKYTNIASINTKDSITKEEIVALSQKVNINPNQFKHIKTKGEFYKKLSRIVKK
ECCCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCHHHHHEECCHHHHHHHHHHHHHH
YKKHDSSAKKL
HHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]