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The map label for this gene is yxdK [H]

Identifier: 52142896

GI number: 52142896

Start: 2475770

End: 2476774

Strand: Direct

Name: yxdK [H]

Synonym: BCZK2344

Alternate gene names: 52142896

Gene position: 2475770-2476774 (Clockwise)

Preceding gene: 52142897

Following gene: 52142895

Centisome position: 46.7

GC content: 32.64

Gene sequence:

>1005_bases
TTGGGATACTGGTATGGAAAAATGATAAGATTGTTTATTCGTGATCATATACCACTTATTTGTTTTACAGCAATCCAATT
ACTATCTATATTTCTCGTATATTGGTTTGATGGACATAACCATATTGCAACGGCATTGTATGCAATGTTTTTAGGTGCCT
TTTTTATGGTAGGCTATTTAGTATTTCGTTACTTTACACATCGTTCTTTTTATGAGCGTTTAGCAAACCCGATGCAATCT
TTAGATGAATCTGTTCAAAATTCTGATTTTGCAGCTATATCTGCTGCTCTTCAACACTTGCTTGAGGTACAATATCGCCA
TTATCAAAATCAGCTTCAGATGCAAGAGAGAAAAAATAATGATCATTTAACTTTTATGAATCAGTGGATTCATCAAATGA
AAACACCTTTATCTGTCATAGAATTAATTACACAAGATGAAGTTGATCCACGCTTCGAAAGTATAAATGAGGAAACAGAT
AGACTGAAAAAGGGGTTAGAGATGGCATTGTATGTTGCACGTTTAGAAGCATTTACACAAGATTTTTATGTAGAAAAAGT
ACAGCTATATAAAATAGTGAATGATTCTGTGCATGAACATAAACGTTTCTTTATCCGGAATTTTGTGTATCCAGAGCTTA
AAGTTGAGAAAGATATTACTGTAGAAAGTGATGCGAAATGGTTACAATTTTTAATTGGACAAATACTATCGAATGCGATT
AAATATTCATCTGGTAGTAGAGAGAAGATTAAAGTGAAAGCTTGTAAGGAAGGTAATACAGTCATACTTGAAATTGCTGA
TAACGGTGTAGGCATACCGAAGCAAGATTTACCAAGAGTATTTAAACCTTTCTTTACAGGAGAAAATGGCAGAGATTTTA
AAGAATCAACTGGAATGGGGCTATATCTTGTATATGAAATTACGAAACAATTAGGACATAGTGTAGAAATCCATTCAGAA
GTTGGAAAAGGTACCGTTGTACGTATTAAATTTTTTAATGTGTAA

Upstream 100 bases:

>100_bases
TAAGTGTAAATACAACACGTGTGCGAAAAAAGTTAAAAACGTTACAGATTAAGGATCCGATTGAAACGATTCGTAGTGTT
GGATATAGACTACATATTAC

Downstream 100 bases:

>100_bases
AAATAAGTAATCTAGGCTAAAGAACTTTGGAGATAAGTTTTTTAGCCTTTTTGTATAGCGGTTATGTGAAATGGTAAAAC
GTCATATTAGTATGTATAAT

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MGYWYGKMIRLFIRDHIPLICFTAIQLLSIFLVYWFDGHNHIATALYAMFLGAFFMVGYLVFRYFTHRSFYERLANPMQS
LDESVQNSDFAAISAALQHLLEVQYRHYQNQLQMQERKNNDHLTFMNQWIHQMKTPLSVIELITQDEVDPRFESINEETD
RLKKGLEMALYVARLEAFTQDFYVEKVQLYKIVNDSVHEHKRFFIRNFVYPELKVEKDITVESDAKWLQFLIGQILSNAI
KYSSGSREKIKVKACKEGNTVILEIADNGVGIPKQDLPRVFKPFFTGENGRDFKESTGMGLYLVYEITKQLGHSVEIHSE
VGKGTVVRIKFFNV

Sequences:

>Translated_334_residues
MGYWYGKMIRLFIRDHIPLICFTAIQLLSIFLVYWFDGHNHIATALYAMFLGAFFMVGYLVFRYFTHRSFYERLANPMQS
LDESVQNSDFAAISAALQHLLEVQYRHYQNQLQMQERKNNDHLTFMNQWIHQMKTPLSVIELITQDEVDPRFESINEETD
RLKKGLEMALYVARLEAFTQDFYVEKVQLYKIVNDSVHEHKRFFIRNFVYPELKVEKDITVESDAKWLQFLIGQILSNAI
KYSSGSREKIKVKACKEGNTVILEIADNGVGIPKQDLPRVFKPFFTGENGRDFKESTGMGLYLVYEITKQLGHSVEIHSE
VGKGTVVRIKFFNV
>Mature_333_residues
GYWYGKMIRLFIRDHIPLICFTAIQLLSIFLVYWFDGHNHIATALYAMFLGAFFMVGYLVFRYFTHRSFYERLANPMQSL
DESVQNSDFAAISAALQHLLEVQYRHYQNQLQMQERKNNDHLTFMNQWIHQMKTPLSVIELITQDEVDPRFESINEETDR
LKKGLEMALYVARLEAFTQDFYVEKVQLYKIVNDSVHEHKRFFIRNFVYPELKVEKDITVESDAKWLQFLIGQILSNAIK
YSSGSREKIKVKACKEGNTVILEIADNGVGIPKQDLPRVFKPFFTGENGRDFKESTGMGLYLVYEITKQLGHSVEIHSEV
GKGTVVRIKFFNV

Specific function: Probable member of the two-component regulatory system yxdK/yxdJ. May activate yxdJ in response to the antibacterial protein LL-37 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=238, Percent_Identity=25.2100840336134, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790436, Length=246, Percent_Identity=25.609756097561, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI48994928, Length=242, Percent_Identity=22.7272727272727, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467 [H]

Pfam domain/function: PF02518 HATPase_c [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 39103; Mature: 38971

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYWYGKMIRLFIRDHIPLICFTAIQLLSIFLVYWFDGHNHIATALYAMFLGAFFMVGYL
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VFRYFTHRSFYERLANPMQSLDESVQNSDFAAISAALQHLLEVQYRHYQNQLQMQERKNN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DHLTFMNQWIHQMKTPLSVIELITQDEVDPRFESINEETDRLKKGLEMALYVARLEAFTQ
CCCHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
DFYVEKVQLYKIVNDSVHEHKRFFIRNFVYPELKVEKDITVESDAKWLQFLIGQILSNAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHH
KYSSGSREKIKVKACKEGNTVILEIADNGVGIPKQDLPRVFKPFFTGENGRDFKESTGMG
HCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHCCCC
LYLVYEITKQLGHSVEIHSEVGKGTVVRIKFFNV
CHHHHHHHHHHCCCEEEHHHCCCCEEEEEEEECC
>Mature Secondary Structure 
GYWYGKMIRLFIRDHIPLICFTAIQLLSIFLVYWFDGHNHIATALYAMFLGAFFMVGYL
CCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VFRYFTHRSFYERLANPMQSLDESVQNSDFAAISAALQHLLEVQYRHYQNQLQMQERKNN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DHLTFMNQWIHQMKTPLSVIELITQDEVDPRFESINEETDRLKKGLEMALYVARLEAFTQ
CCCHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
DFYVEKVQLYKIVNDSVHEHKRFFIRNFVYPELKVEKDITVESDAKWLQFLIGQILSNAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHH
KYSSGSREKIKVKACKEGNTVILEIADNGVGIPKQDLPRVFKPFFTGENGRDFKESTGMG
HCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHCCCC
LYLVYEITKQLGHSVEIHSEVGKGTVVRIKFFNV
CHHHHHHHHHHCCCEEEHHHCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7952181; 9384377; 8867804 [H]