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The map label for this gene is yqgF [H]

Identifier: 52142859

GI number: 52142859

Start: 2515857

End: 2517983

Strand: Direct

Name: yqgF [H]

Synonym: BCZK2381

Alternate gene names: 52142859

Gene position: 2515857-2517983 (Clockwise)

Preceding gene: 52142860

Following gene: 52142857

Centisome position: 47.46

GC content: 33.71

Gene sequence:

>2127_bases
GTGAAAAAACAAGAGAAAAAAAGTGGTAGAGCAGTAACAATGCGGTTAAACATTCTATTTTTTTGTGTATTTATATTATT
TTCTGCCATGATCATACAATTAGGTAAAGTACAAATTATCGATGGTGAGACGTATAAAAATGAAGTAGAGAAAAGAGAAA
ATGCAACCGTAAGCCTTTCTGTCCCGCGTGGAAAAATATTTGATCGAGAAGGGAATCCAGTAGTTGATAATAAATCTTTA
CGTACAATTACATATACAAAGATGAAAGGTGTAAAATCAGAAGAAATATTAAAAACAGCAAGACAACTTGCAGACATAAT
TGAAATACCACAAGAGGATATAGATAAACTAACTGAGACGGATAAGAAAGATTTTTGGATGCAATTAAATCCGACACTAA
CCGAAAAATTAGTATCTAAAAAAGAAATAAATAAGTTCAGAGATAAAGATATTACCGGGAAAAATTTAGATAAAAAAATT
GAAGAGTTAAAAAGAAAACGAGTTACGGATAAAAATCTTCAGGATTTAACTGATAAAGATATAAAAGTGTTAGCTATTAA
AAGTAAGATGACTTCTGGTTATCAAATGGCTCCTCAAATTATTAAAAAAGACGTTAGTGAAAAGGAATTTACTATAATTA
GTGAAAGTTTGGCGAATCTCCCAGGTGTAGACGTGTCGGTTGATTGGGAGAGAGTGTATGTGAATGATGGATTATTCCGA
TCCGTTCTTGGAAATGTTTCTAATTCCGATGAAGGATTACCAAGTGAACGATTAGATTATTACTTGGTACGTGATTATAG
CCGAAATGATAGGGTTGGAAAAAGTTATATCGAGCAGCAATATGAAGATGTACTTCATGGTACAAAAAAAGAAGTAAGAA
GCGTTGCAGATAAACAAGGTACTACAATTAGAACGGAAACAATTTCTGAGGGAAAGAGCGGTAAGAACTTAACTTTAACA
ATAGATATGGAATTACAGAAAAAGGTAGAAGAAAGTATAGAAAAAATATTAAAGGCATATAAAGGATCAGAATCCATGTT
GGACCGTGCTTTCGTTGTAATGATGAATCCGAAAAACGGACAAGTATTATCAATGGCTGGCAAAAGACTTGTAGAAAAAG
ACGGGAAAACAGAAATTGAAGACTATGCATTAGGTACAATGACTAGTTCATATGAGCTGGGATCAACAGTTAAAGGTGCC
ACAGTTTTAACTGGATTTGAAACGAAAGCTATAACACCAGGTACTTATTTTTATGATGCACCTATGAAGTTTAAAGGTAC
TAGGGAGAAGAAGTCTTGGAAAGAGTTTGGAAATATTGATGATTTAAGAGCGTTACAAGTCTCTTCAAACGTTTATATGT
TCCATACAGCATTAAAAATTGCAGGTGTGGATTATGTGAGAAATAGTTCATTAAATATTAAACAGGAATACTTTGATAAA
ATGAGGTACTATTTTAGACAATTCGGATTAGGTGTTCCAACGGGTATTGATTTACCGAATGAAACAGCTGGACAAATAGG
TAAAAAAGATAATCAACCTGGTTTCTTATTAGATTACTCAATTGGCCAGTATGACACGTATACACCACTTCAGCTTGTAC
AGTATATTTCAACAATTGCAAACGGCGGATATCGAATGAAGCCACAAATTGTTCAAGAAATAAGAGAGCAAACTTCGCAA
AAAGATGAGATTGGTAAAGTTGTGCATGCAGTAGAACCAATTGTTTTAAATAAAGTTGATATGAAAGAGGAATATATAAA
GCAAGTAAAAGAAGGATTTAGAAAGGTATTCCAAGAAGGAGATGGAACAGGAGTAAGGGCGTTCCAAAAAGCATCTTATA
AACCAGCAGGTAAAACAGGAACAGCACAGACAGTTTACGGTGGAGAAAGTGATATTGGAAGAAATGAAAAGGGCGAGAGA
AGAGAATGTTATAACTTAACGTTAGCAGGGTATGCGCCATATGATAATCCAGAAGTAGCATTCTCTGTAGTTGTGCCGTG
GGTTATGAATGATAAATCTGGTATTAACTCTGATATTGGAAAAGAAGTTTTGGATGCTTATTTTGAATTGAAAAATAAGC
GATTGACTGGAGAGACTTTACAAATAGATGGCTCTCAAGAAGGTTAA

Upstream 100 bases:

>100_bases
ATTAGTATTTGTGCAAGGTAATGTATAGAAAACGTGCATTACTTTTAATATATAGATTCAATTATTAATAGAAATACAGT
AAGGAGGAGATTATGACAAG

Downstream 100 bases:

>100_bases
AACATATGAAATAATATAGAAACTAGAGTCATTTAATTTAGGGATAGATTCAAAATGGGTGATAGAAAGGTAAAATCATT
CTATCAATTGTTCACGTTTT

Product: penicillin-binding protein transpeptidase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 708; Mature: 708

Protein sequence:

>708_residues
MKKQEKKSGRAVTMRLNILFFCVFILFSAMIIQLGKVQIIDGETYKNEVEKRENATVSLSVPRGKIFDREGNPVVDNKSL
RTITYTKMKGVKSEEILKTARQLADIIEIPQEDIDKLTETDKKDFWMQLNPTLTEKLVSKKEINKFRDKDITGKNLDKKI
EELKRKRVTDKNLQDLTDKDIKVLAIKSKMTSGYQMAPQIIKKDVSEKEFTIISESLANLPGVDVSVDWERVYVNDGLFR
SVLGNVSNSDEGLPSERLDYYLVRDYSRNDRVGKSYIEQQYEDVLHGTKKEVRSVADKQGTTIRTETISEGKSGKNLTLT
IDMELQKKVEESIEKILKAYKGSESMLDRAFVVMMNPKNGQVLSMAGKRLVEKDGKTEIEDYALGTMTSSYELGSTVKGA
TVLTGFETKAITPGTYFYDAPMKFKGTREKKSWKEFGNIDDLRALQVSSNVYMFHTALKIAGVDYVRNSSLNIKQEYFDK
MRYYFRQFGLGVPTGIDLPNETAGQIGKKDNQPGFLLDYSIGQYDTYTPLQLVQYISTIANGGYRMKPQIVQEIREQTSQ
KDEIGKVVHAVEPIVLNKVDMKEEYIKQVKEGFRKVFQEGDGTGVRAFQKASYKPAGKTGTAQTVYGGESDIGRNEKGER
RECYNLTLAGYAPYDNPEVAFSVVVPWVMNDKSGINSDIGKEVLDAYFELKNKRLTGETLQIDGSQEG

Sequences:

>Translated_708_residues
MKKQEKKSGRAVTMRLNILFFCVFILFSAMIIQLGKVQIIDGETYKNEVEKRENATVSLSVPRGKIFDREGNPVVDNKSL
RTITYTKMKGVKSEEILKTARQLADIIEIPQEDIDKLTETDKKDFWMQLNPTLTEKLVSKKEINKFRDKDITGKNLDKKI
EELKRKRVTDKNLQDLTDKDIKVLAIKSKMTSGYQMAPQIIKKDVSEKEFTIISESLANLPGVDVSVDWERVYVNDGLFR
SVLGNVSNSDEGLPSERLDYYLVRDYSRNDRVGKSYIEQQYEDVLHGTKKEVRSVADKQGTTIRTETISEGKSGKNLTLT
IDMELQKKVEESIEKILKAYKGSESMLDRAFVVMMNPKNGQVLSMAGKRLVEKDGKTEIEDYALGTMTSSYELGSTVKGA
TVLTGFETKAITPGTYFYDAPMKFKGTREKKSWKEFGNIDDLRALQVSSNVYMFHTALKIAGVDYVRNSSLNIKQEYFDK
MRYYFRQFGLGVPTGIDLPNETAGQIGKKDNQPGFLLDYSIGQYDTYTPLQLVQYISTIANGGYRMKPQIVQEIREQTSQ
KDEIGKVVHAVEPIVLNKVDMKEEYIKQVKEGFRKVFQEGDGTGVRAFQKASYKPAGKTGTAQTVYGGESDIGRNEKGER
RECYNLTLAGYAPYDNPEVAFSVVVPWVMNDKSGINSDIGKEVLDAYFELKNKRLTGETLQIDGSQEG
>Mature_708_residues
MKKQEKKSGRAVTMRLNILFFCVFILFSAMIIQLGKVQIIDGETYKNEVEKRENATVSLSVPRGKIFDREGNPVVDNKSL
RTITYTKMKGVKSEEILKTARQLADIIEIPQEDIDKLTETDKKDFWMQLNPTLTEKLVSKKEINKFRDKDITGKNLDKKI
EELKRKRVTDKNLQDLTDKDIKVLAIKSKMTSGYQMAPQIIKKDVSEKEFTIISESLANLPGVDVSVDWERVYVNDGLFR
SVLGNVSNSDEGLPSERLDYYLVRDYSRNDRVGKSYIEQQYEDVLHGTKKEVRSVADKQGTTIRTETISEGKSGKNLTLT
IDMELQKKVEESIEKILKAYKGSESMLDRAFVVMMNPKNGQVLSMAGKRLVEKDGKTEIEDYALGTMTSSYELGSTVKGA
TVLTGFETKAITPGTYFYDAPMKFKGTREKKSWKEFGNIDDLRALQVSSNVYMFHTALKIAGVDYVRNSSLNIKQEYFDK
MRYYFRQFGLGVPTGIDLPNETAGQIGKKDNQPGFLLDYSIGQYDTYTPLQLVQYISTIANGGYRMKPQIVQEIREQTSQ
KDEIGKVVHAVEPIVLNKVDMKEEYIKQVKEGFRKVFQEGDGTGVRAFQKASYKPAGKTGTAQTVYGGESDIGRNEKGER
RECYNLTLAGYAPYDNPEVAFSVVVPWVMNDKSGINSDIGKEVLDAYFELKNKRLTGETLQIDGSQEG

Specific function: Cell Wall Formation; Pbp-2 Is Responsible For The Determination Of The Rod Shape Of The Cell. Its Synthesize Cross- Linked Peptidoglycan From The Lipid Intermediates. [C]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1786854, Length=541, Percent_Identity=25.3234750462107, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1786272, Length=415, Percent_Identity=24.8192771084337, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005311
- InterPro:   IPR001460 [H]

Pfam domain/function: PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 80159; Mature: 80159

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKQEKKSGRAVTMRLNILFFCVFILFSAMIIQLGKVQIIDGETYKNEVEKRENATVSLS
CCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHCCCEEEEE
VPRGKIFDREGNPVVDNKSLRTITYTKMKGVKSEEILKTARQLADIIEIPQEDIDKLTET
CCCCCEECCCCCCCCCCCCCEEEEEHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCC
DKKDFWMQLNPTLTEKLVSKKEINKFRDKDITGKNLDKKIEELKRKRVTDKNLQDLTDKD
CCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHCCCCC
IKVLAIKSKMTSGYQMAPQIIKKDVSEKEFTIISESLANLPGVDVSVDWERVYVNDGLFR
EEEEEEECHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEECCEEEEECCCHHH
SVLGNVSNSDEGLPSERLDYYLVRDYSRNDRVGKSYIEQQYEDVLHGTKKEVRSVADKQG
HHHCCCCCCCCCCCHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
TTIRTETISEGKSGKNLTLTIDMELQKKVEESIEKILKAYKGSESMLDRAFVVMMNPKNG
CEEEEEECCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHCCCHHHHCCEEEEEECCCCC
QVLSMAGKRLVEKDGKTEIEDYALGTMTSSYELGSTVKGATVLTGFETKAITPGTYFYDA
CEEHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCCCEEECC
PMKFKGTREKKSWKEFGNIDDLRALQVSSNVYMFHTALKIAGVDYVRNSSLNIKQEYFDK
CCCCCCCCCHHHHHHHCCCCCCEEEEECCCEEEEEHHHHHHCHHHHCCCCCCCHHHHHHH
MRYYFRQFGLGVPTGIDLPNETAGQIGKKDNQPGFLLDYSIGQYDTYTPLQLVQYISTIA
HHHHHHHHCCCCCCCCCCCCCHHHHCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHH
NGGYRMKPQIVQEIREQTSQKDEIGKVVHAVEPIVLNKVDMKEEYIKQVKEGFRKVFQEG
CCCEEECHHHHHHHHHHHCCHHHHHHHHHHHCHHHHCCCCHHHHHHHHHHHHHHHHHHCC
DGTGVRAFQKASYKPAGKTGTAQTVYGGESDIGRNEKGERRECYNLTLAGYAPYDNPEVA
CCCCHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCCCHHHEEEEEECCCCCCCCCEE
FSVVVPWVMNDKSGINSDIGKEVLDAYFELKNKRLTGETLQIDGSQEG
EEEEECEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCC
>Mature Secondary Structure
MKKQEKKSGRAVTMRLNILFFCVFILFSAMIIQLGKVQIIDGETYKNEVEKRENATVSLS
CCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHCCCEEEEE
VPRGKIFDREGNPVVDNKSLRTITYTKMKGVKSEEILKTARQLADIIEIPQEDIDKLTET
CCCCCEECCCCCCCCCCCCCEEEEEHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCC
DKKDFWMQLNPTLTEKLVSKKEINKFRDKDITGKNLDKKIEELKRKRVTDKNLQDLTDKD
CCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHCCCCC
IKVLAIKSKMTSGYQMAPQIIKKDVSEKEFTIISESLANLPGVDVSVDWERVYVNDGLFR
EEEEEEECHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEECCEEEEECCCHHH
SVLGNVSNSDEGLPSERLDYYLVRDYSRNDRVGKSYIEQQYEDVLHGTKKEVRSVADKQG
HHHCCCCCCCCCCCHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
TTIRTETISEGKSGKNLTLTIDMELQKKVEESIEKILKAYKGSESMLDRAFVVMMNPKNG
CEEEEEECCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHCCCHHHHCCEEEEEECCCCC
QVLSMAGKRLVEKDGKTEIEDYALGTMTSSYELGSTVKGATVLTGFETKAITPGTYFYDA
CEEHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCCCEEECC
PMKFKGTREKKSWKEFGNIDDLRALQVSSNVYMFHTALKIAGVDYVRNSSLNIKQEYFDK
CCCCCCCCCHHHHHHHCCCCCCEEEEECCCEEEEEHHHHHHCHHHHCCCCCCCHHHHHHH
MRYYFRQFGLGVPTGIDLPNETAGQIGKKDNQPGFLLDYSIGQYDTYTPLQLVQYISTIA
HHHHHHHHCCCCCCCCCCCCCHHHHCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHH
NGGYRMKPQIVQEIREQTSQKDEIGKVVHAVEPIVLNKVDMKEEYIKQVKEGFRKVFQEG
CCCEEECHHHHHHHHHHHCCHHHHHHHHHHHCHHHHCCCCHHHHHHHHHHHHHHHHHHCC
DGTGVRAFQKASYKPAGKTGTAQTVYGGESDIGRNEKGERRECYNLTLAGYAPYDNPEVA
CCCCHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCCCHHHEEEEEECCCCCCCCCEE
FSVVVPWVMNDKSGINSDIGKEVLDAYFELKNKRLTGETLQIDGSQEG
EEEEECEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]