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The map label for this gene is blaR1 [H]

Identifier: 52142832

GI number: 52142832

Start: 2544997

End: 2546856

Strand: Direct

Name: blaR1 [H]

Synonym: BCZK2408

Alternate gene names: 52142832

Gene position: 2544997-2546856 (Clockwise)

Preceding gene: 52142834

Following gene: 52142831

Centisome position: 48.01

GC content: 33.92

Gene sequence:

>1860_bases
ATGATAGATATGTTTGTAAACGTCTATCTACCTCGCTTTTTTGATTGGGTGATAGAAACTGCCATTATGGCAAGTATATT
AGTTGGCCTAATCTTATGTATCAAAATCTTGCTTAGAAATAAGTTACCCCCACGATGGCAGTATCTATTATGGATAATAT
TAATTGTAAGACTTTTATTGCCATGGTCACCAGATAGTTCTTACAGTATCTATTCTATTCTTTCGTACAGTAATGGAACT
CCAGTTACTTCTCACCAAGACTCCACAGATCGTCGTATACAAGGATCGACAGCTATAGGTGGTACAAAGACCTATACATA
TGGTTCTGCACAAACAGCTGAAAAAAGTAAGAAACAAACGCATAATAATGAAACGAAAAATGACGAAACGGTTTCATTTT
ATACAATCGTTTTATATATTTGGCTTGCTGTGGTTATCATTCTATCTTTTGCCACCATCATTATGAATAAGCGTTTACTC
TTCTATATAAAAAAGCAACCTGTTATTACAGATGAAAGGATTAGTAAAATCTTTGAGAGTTGTAAGAAATCTATGTCCGT
TAAGCGAGATATCCCACTCCTCTTAGCTGGGAAAATTGCAAGTCCAACTGTTTTCGGATTCCTTAGACCAAGGGTGTTAT
TGTCAAGTGCACATATGAAAGTATTAGATGAGCAACAGTTACGATACATCTTTCATCATGAATTAGCTCATATCAAACGA
AGAGATATTGGTGTGAATTGGCTTATGCATGGTTTACTGATTCTAAATTGGTTTAACCCAATCCTTTGGTATGCCTACTC
ATGCATGCGGGAAGATCAGGAACTGGCGTGTGATGCATTTGCTCTTACATATATAGATTCAGAGGAAAAACTGGCATATG
GTCATACCATTATTACCCTTTTAGAATACTACTCAAGTTATTATCAAGTACCAAGCTTAGCGAACTTAAGTAGAAATAAA
AGAACATTAAAAAGGAGAATTCTTATGATTAAAAAATTTAAAAAGAACTCTTATCGTTGGTCTGCATTTGGAGTTGTTGC
TATTCTTGCTGTATCATCTGTGTCTTTATTAAATGCACATGCAGATATACCAAATAACTCGCAGAAAGAACCAACGGAAG
TGAAAAATAATATCAAAGAAGCAAAAGCACAAACTAAAGTTCCTATTCAGCAAATTGTAGAAAAGATGATTGGTACAAAA
GAACAAGCATTTGCAGAATTTCATGTTTCAGAGGGGCGATATGAATATATACTTGAAGAAATGGAAGTGGCACGGAATCT
GTTAACAAAAGAAGAATTTTACAAATTTATCAAATTGCAAACAGAGGAGTATATCATAGACAAAAAGATAAGATCAGTAG
GGACACCTGAAGATTTAGAACCAGACGATCAAAAAAAATTAGAGGAGAATAGCAAAGCTATTGAACCATTATGGGGAAAA
ATTTATTCGCAGTTCACATCTCGTTCATTTGATTTTCCAATCAAGAAACCAAATTATGTAGCGAAAGGTTATGAACTAAA
GAGGGAAAAAGTTGAACCAGTAATTACAACAAAAAAGCTGAATCCTATCATTAGCTCAGAATATAGAGCCGGGGAGTTTG
GTTATACAATTTATCAATCTGACATTTTAGAAAGAGGAAGAGATCCATTTTATCAGTGGATTAATGACAATGACAAGATA
GAAAATTATGAACTGGAAGGAGCACAATTCATATTTGGTAAAATGACCGGGAGTAATGTAAAGGGCATGAAAATGATTGT
TCCTGCAAAAGGAAAGGACAGTACTTATCAAGTTGTAATCATTGATGATGTTTTAAATAAGGCTGAATTAGAGAAAATCA
TGATTTCCTTTTTGAAATAA

Upstream 100 bases:

>100_bases
ATTTCTTAAAAGAAGAAAAGCTGTCTTCAGAGGATATTAACGAACTCAAACGTATTTTAGATGAGAAGAATGAGGAAAAT
CAGAGGAAGGATAGATTATA

Downstream 100 bases:

>100_bases
AGACAGAGTCTCAAGAAAAGAATCTTGAGACTCTGTTTTTATTTCAGTTCGAATGAAATCTTCATGTAATAAAAGAAATT
AATAATCTATAAAACAAAAA

Product: beta-lactamase regulatory protein 1; methicillin resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 619; Mature: 619

Protein sequence:

>619_residues
MIDMFVNVYLPRFFDWVIETAIMASILVGLILCIKILLRNKLPPRWQYLLWIILIVRLLLPWSPDSSYSIYSILSYSNGT
PVTSHQDSTDRRIQGSTAIGGTKTYTYGSAQTAEKSKKQTHNNETKNDETVSFYTIVLYIWLAVVIILSFATIIMNKRLL
FYIKKQPVITDERISKIFESCKKSMSVKRDIPLLLAGKIASPTVFGFLRPRVLLSSAHMKVLDEQQLRYIFHHELAHIKR
RDIGVNWLMHGLLILNWFNPILWYAYSCMREDQELACDAFALTYIDSEEKLAYGHTIITLLEYYSSYYQVPSLANLSRNK
RTLKRRILMIKKFKKNSYRWSAFGVVAILAVSSVSLLNAHADIPNNSQKEPTEVKNNIKEAKAQTKVPIQQIVEKMIGTK
EQAFAEFHVSEGRYEYILEEMEVARNLLTKEEFYKFIKLQTEEYIIDKKIRSVGTPEDLEPDDQKKLEENSKAIEPLWGK
IYSQFTSRSFDFPIKKPNYVAKGYELKREKVEPVITTKKLNPIISSEYRAGEFGYTIYQSDILERGRDPFYQWINDNDKI
ENYELEGAQFIFGKMTGSNVKGMKMIVPAKGKDSTYQVVIIDDVLNKAELEKIMISFLK

Sequences:

>Translated_619_residues
MIDMFVNVYLPRFFDWVIETAIMASILVGLILCIKILLRNKLPPRWQYLLWIILIVRLLLPWSPDSSYSIYSILSYSNGT
PVTSHQDSTDRRIQGSTAIGGTKTYTYGSAQTAEKSKKQTHNNETKNDETVSFYTIVLYIWLAVVIILSFATIIMNKRLL
FYIKKQPVITDERISKIFESCKKSMSVKRDIPLLLAGKIASPTVFGFLRPRVLLSSAHMKVLDEQQLRYIFHHELAHIKR
RDIGVNWLMHGLLILNWFNPILWYAYSCMREDQELACDAFALTYIDSEEKLAYGHTIITLLEYYSSYYQVPSLANLSRNK
RTLKRRILMIKKFKKNSYRWSAFGVVAILAVSSVSLLNAHADIPNNSQKEPTEVKNNIKEAKAQTKVPIQQIVEKMIGTK
EQAFAEFHVSEGRYEYILEEMEVARNLLTKEEFYKFIKLQTEEYIIDKKIRSVGTPEDLEPDDQKKLEENSKAIEPLWGK
IYSQFTSRSFDFPIKKPNYVAKGYELKREKVEPVITTKKLNPIISSEYRAGEFGYTIYQSDILERGRDPFYQWINDNDKI
ENYELEGAQFIFGKMTGSNVKGMKMIVPAKGKDSTYQVVIIDDVLNKAELEKIMISFLK
>Mature_619_residues
MIDMFVNVYLPRFFDWVIETAIMASILVGLILCIKILLRNKLPPRWQYLLWIILIVRLLLPWSPDSSYSIYSILSYSNGT
PVTSHQDSTDRRIQGSTAIGGTKTYTYGSAQTAEKSKKQTHNNETKNDETVSFYTIVLYIWLAVVIILSFATIIMNKRLL
FYIKKQPVITDERISKIFESCKKSMSVKRDIPLLLAGKIASPTVFGFLRPRVLLSSAHMKVLDEQQLRYIFHHELAHIKR
RDIGVNWLMHGLLILNWFNPILWYAYSCMREDQELACDAFALTYIDSEEKLAYGHTIITLLEYYSSYYQVPSLANLSRNK
RTLKRRILMIKKFKKNSYRWSAFGVVAILAVSSVSLLNAHADIPNNSQKEPTEVKNNIKEAKAQTKVPIQQIVEKMIGTK
EQAFAEFHVSEGRYEYILEEMEVARNLLTKEEFYKFIKLQTEEYIIDKKIRSVGTPEDLEPDDQKKLEENSKAIEPLWGK
IYSQFTSRSFDFPIKKPNYVAKGYELKREKVEPVITTKKLNPIISSEYRAGEFGYTIYQSDILERGRDPFYQWINDNDKI
ENYELEGAQFIFGKMTGSNVKGMKMIVPAKGKDSTYQVVIIDDVLNKAELEKIMISFLK

Specific function: BlaR1 is a potential penicillin-binding protein required for induction of beta-lactamase in Bacillus licheniformis [H]

COG id: COG4219

COG function: function code KT; Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M56 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001460
- InterPro:   IPR008756 [H]

Pfam domain/function: PF05569 Peptidase_M56; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 71773; Mature: 71773

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDMFVNVYLPRFFDWVIETAIMASILVGLILCIKILLRNKLPPRWQYLLWIILIVRLLL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC
PWSPDSSYSIYSILSYSNGTPVTSHQDSTDRRIQGSTAIGGTKTYTYGSAQTAEKSKKQT
CCCCCCCCCCEEEEECCCCCCCCCCCCCCCCEECCCCCCCCCCEEECCCHHHHHHHHHHH
HNNETKNDETVSFYTIVLYIWLAVVIILSFATIIMNKRLLFYIKKQPVITDERISKIFES
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHH
CKKSMSVKRDIPLLLAGKIASPTVFGFLRPRVLLSSAHMKVLDEQQLRYIFHHELAHIKR
HHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDIGVNWLMHGLLILNWFNPILWYAYSCMREDQELACDAFALTYIDSEEKLAYGHTIITL
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHEEEEEECCCCHHHHHHHHHHH
LEYYSSYYQVPSLANLSRNKRTLKRRILMIKKFKKNSYRWSAFGVVAILAVSSVSLLNAH
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHC
ADIPNNSQKEPTEVKNNIKEAKAQTKVPIQQIVEKMIGTKEQAFAEFHVSEGRYEYILEE
CCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHH
MEVARNLLTKEEFYKFIKLQTEEYIIDKKIRSVGTPEDLEPDDQKKLEENSKAIEPLWGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCHHHHHHHHH
IYSQFTSRSFDFPIKKPNYVAKGYELKREKVEPVITTKKLNPIISSEYRAGEFGYTIYQS
HHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHCCCHHCCCCCCCCCCHHHHHH
DILERGRDPFYQWINDNDKIENYELEGAQFIFGKMTGSNVKGMKMIVPAKGKDSTYQVVI
HHHHCCCCHHHHHCCCCCCCCCEECCCCEEEEEECCCCCCCCEEEEEECCCCCCEEEEEE
IDDVLNKAELEKIMISFLK
EHHHCCHHHHHHHHHHHCC
>Mature Secondary Structure
MIDMFVNVYLPRFFDWVIETAIMASILVGLILCIKILLRNKLPPRWQYLLWIILIVRLLL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC
PWSPDSSYSIYSILSYSNGTPVTSHQDSTDRRIQGSTAIGGTKTYTYGSAQTAEKSKKQT
CCCCCCCCCCEEEEECCCCCCCCCCCCCCCCEECCCCCCCCCCEEECCCHHHHHHHHHHH
HNNETKNDETVSFYTIVLYIWLAVVIILSFATIIMNKRLLFYIKKQPVITDERISKIFES
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHH
CKKSMSVKRDIPLLLAGKIASPTVFGFLRPRVLLSSAHMKVLDEQQLRYIFHHELAHIKR
HHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDIGVNWLMHGLLILNWFNPILWYAYSCMREDQELACDAFALTYIDSEEKLAYGHTIITL
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHEEEEEECCCCHHHHHHHHHHH
LEYYSSYYQVPSLANLSRNKRTLKRRILMIKKFKKNSYRWSAFGVVAILAVSSVSLLNAH
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHC
ADIPNNSQKEPTEVKNNIKEAKAQTKVPIQQIVEKMIGTKEQAFAEFHVSEGRYEYILEE
CCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHH
MEVARNLLTKEEFYKFIKLQTEEYIIDKKIRSVGTPEDLEPDDQKKLEENSKAIEPLWGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCHHHHHHHHH
IYSQFTSRSFDFPIKKPNYVAKGYELKREKVEPVITTKKLNPIISSEYRAGEFGYTIYQS
HHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHCCCHHCCCCCCCCCCHHHHHH
DILERGRDPFYQWINDNDKIENYELEGAQFIFGKMTGSNVKGMKMIVPAKGKDSTYQVVI
HHHHCCCCHHHHHCCCCCCCCCEECCCCEEEEEECCCCCCCCEEEEEECCCCCCEEEEEE
IDDVLNKAELEKIMISFLK
EHHHCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3040663; 3260234; 2404938 [H]