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The map label for this gene is katX [H]

Identifier: 52142495

GI number: 52142495

Start: 2865618

End: 2866994

Strand: Direct

Name: katX [H]

Synonym: BCZK2747

Alternate gene names: 52142495

Gene position: 2865618-2866994 (Clockwise)

Preceding gene: 52142503

Following gene: 52142480

Centisome position: 54.06

GC content: 36.89

Gene sequence:

>1377_bases
ATGGGTGAAAACCATGATAAACAGAGGCAATCTTTACTAGGGAAAGACTTTAATGAAATTGGAGAACGTAATGAACAAGC
AATCCTTCACTCTCAAACAGTTGGTTCACGTGGACCTGTTCTAGAGCAAGATAGTGTGCTTCACGAGGCGTTACAAGAAT
TTATTCACGAAAAAATTTTAGAAAGACCTGTTCATGTAAAAGGATTTGGTGCATTCGGTTATTTTCAAACGATCTATCCA
ATGTCCGAACATACTAAACTAAGTTTTCTACAACATTCTAATGAGAAAGTTCCTGTTATGGTTCGATTTTCATTAGCTGT
TAGTACGAAAGGAACACCTGACACTGCTAGAAATGTACGTGGTTTTTCTACAAAATTCTATACAAAAGAAGGTATTTTCG
ATCTATTATGTAATCACATTCCTGTCTTTTCTGTTCGCGATCCGATGCGTTTCCCTGAAACCATTCAAGCGTTGTCACCT
TCACCTAAAAATAACTTACTAGACCCGAATAGATTTTGGAGTTTTGTTGCTAGAGCACCTGAATCTATACATTTCGTTGT
CCGTTTGTACTCTGATAATGGTACGGCCAAAAGCCTTCGCCGCATTCCAGGACATAGTGTAAATACATATGTTTGGAGAA
ATGCAGAAGGCAATCGAAAGTATGTAAAGTATCATTGGTACCCATTTGAAGGTGTACAATTCATTACTAGCGAGGAAGCA
AATAAACTGGCTGCTGAAAATCCAGATTATAGCGGGAAAGATTTATATGATGCAATTGCAAATGGTAAACCAGTGGAATA
TGGTTTATACGTCCAGCTTATGGACCCGAAAGATGAAACGCATCTTTCTTACGATCCTTTAGATGATACAAAAATATGGG
ATGAAAAAGCGTATCCTCTTATACCAGTCGGCAAAATGGTATTAAATAAAAACCCTGAAAATTATATGGAACAAGTAGAA
AAAGTCGCTTTCTCCCCTTCTAATTTACTAGACGGCGCAGAATTATCAGATGATAAAATGTTGCAAGGACGTGCAAACAT
TTATAGTGATTCTCAAAGAAGAAGAATTGGTCCTGAATTTCGTAAATTAGCAATTAACCAACAGCAAGATTGGACACCTG
CTAATCAAATAACGAGCGGTGACGGAAGGTACGTTGAAGGTAAACTTGAGAGAACTTCTATACCGAAACAAGATGACTTT
ACACAGGCTGGTGAATTTTATGCGAAGTTAAAACTGATAGAAAAAGAACATCTTGCTGAAAACTTAGCTAGTGACTTGAA
AGTTATATCCGATGATATTAGAAAGGTCGTTCTAGGGTATTTTCATAAAGTGTCAGCTGATTTGGTGAAGAGGATTGAAA
CCGAAATAGAAAAATAA

Upstream 100 bases:

>100_bases
AGCGGTCTGTTACTATTTTGAACTTTGCGTGTTATACATAATCAATGCTATAAAATCATATTTAGTAACAATGAACAAAA
AAGATTTGGAGGCTATATTG

Downstream 100 bases:

>100_bases
TAAGACGAAAGCACACATCGACTTTTATTCATACAAAAGAGCCATTTATCTAACCGTTTTTAGTCAGCTAAATGGCTCTT
TTTTATTTTTTCACCACATT

Product: catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 457

Protein sequence:

>458_residues
MGENHDKQRQSLLGKDFNEIGERNEQAILHSQTVGSRGPVLEQDSVLHEALQEFIHEKILERPVHVKGFGAFGYFQTIYP
MSEHTKLSFLQHSNEKVPVMVRFSLAVSTKGTPDTARNVRGFSTKFYTKEGIFDLLCNHIPVFSVRDPMRFPETIQALSP
SPKNNLLDPNRFWSFVARAPESIHFVVRLYSDNGTAKSLRRIPGHSVNTYVWRNAEGNRKYVKYHWYPFEGVQFITSEEA
NKLAAENPDYSGKDLYDAIANGKPVEYGLYVQLMDPKDETHLSYDPLDDTKIWDEKAYPLIPVGKMVLNKNPENYMEQVE
KVAFSPSNLLDGAELSDDKMLQGRANIYSDSQRRRIGPEFRKLAINQQQDWTPANQITSGDGRYVEGKLERTSIPKQDDF
TQAGEFYAKLKLIEKEHLAENLASDLKVISDDIRKVVLGYFHKVSADLVKRIETEIEK

Sequences:

>Translated_458_residues
MGENHDKQRQSLLGKDFNEIGERNEQAILHSQTVGSRGPVLEQDSVLHEALQEFIHEKILERPVHVKGFGAFGYFQTIYP
MSEHTKLSFLQHSNEKVPVMVRFSLAVSTKGTPDTARNVRGFSTKFYTKEGIFDLLCNHIPVFSVRDPMRFPETIQALSP
SPKNNLLDPNRFWSFVARAPESIHFVVRLYSDNGTAKSLRRIPGHSVNTYVWRNAEGNRKYVKYHWYPFEGVQFITSEEA
NKLAAENPDYSGKDLYDAIANGKPVEYGLYVQLMDPKDETHLSYDPLDDTKIWDEKAYPLIPVGKMVLNKNPENYMEQVE
KVAFSPSNLLDGAELSDDKMLQGRANIYSDSQRRRIGPEFRKLAINQQQDWTPANQITSGDGRYVEGKLERTSIPKQDDF
TQAGEFYAKLKLIEKEHLAENLASDLKVISDDIRKVVLGYFHKVSADLVKRIETEIEK
>Mature_457_residues
GENHDKQRQSLLGKDFNEIGERNEQAILHSQTVGSRGPVLEQDSVLHEALQEFIHEKILERPVHVKGFGAFGYFQTIYPM
SEHTKLSFLQHSNEKVPVMVRFSLAVSTKGTPDTARNVRGFSTKFYTKEGIFDLLCNHIPVFSVRDPMRFPETIQALSPS
PKNNLLDPNRFWSFVARAPESIHFVVRLYSDNGTAKSLRRIPGHSVNTYVWRNAEGNRKYVKYHWYPFEGVQFITSEEAN
KLAAENPDYSGKDLYDAIANGKPVEYGLYVQLMDPKDETHLSYDPLDDTKIWDEKAYPLIPVGKMVLNKNPENYMEQVEK
VAFSPSNLLDGAELSDDKMLQGRANIYSDSQRRRIGPEFRKLAINQQQDWTPANQITSGDGRYVEGKLERTSIPKQDDFT
QAGEFYAKLKLIEKEHLAENLASDLKVISDDIRKVVLGYFHKVSADLVKRIETEIEK

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide. Involved in sporulation [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family. HPII subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=472, Percent_Identity=36.4406779661017, Blast_Score=311, Evalue=7e-85,
Organism=Escherichia coli, GI48994891, Length=343, Percent_Identity=40.5247813411079, Blast_Score=273, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI71998444, Length=456, Percent_Identity=35.9649122807018, Blast_Score=299, Evalue=2e-81,
Organism=Caenorhabditis elegans, GI25147792, Length=446, Percent_Identity=36.322869955157, Blast_Score=294, Evalue=5e-80,
Organism=Caenorhabditis elegans, GI25151141, Length=446, Percent_Identity=36.322869955157, Blast_Score=294, Evalue=7e-80,
Organism=Saccharomyces cerevisiae, GI6320462, Length=339, Percent_Identity=40.117994100295, Blast_Score=265, Evalue=8e-72,
Organism=Saccharomyces cerevisiae, GI6321525, Length=373, Percent_Identity=34.5844504021448, Blast_Score=227, Evalue=2e-60,
Organism=Drosophila melanogaster, GI17981717, Length=460, Percent_Identity=36.5217391304348, Blast_Score=307, Evalue=1e-83,
Organism=Drosophila melanogaster, GI19920968, Length=335, Percent_Identity=40, Blast_Score=289, Evalue=2e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614
- InterPro:   IPR002818 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel; PF01965 DJ-1_PfpI [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 52436; Mature: 52305

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGENHDKQRQSLLGKDFNEIGERNEQAILHSQTVGSRGPVLEQDSVLHEALQEFIHEKIL
CCCCHHHHHHHHHCCCHHHHCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
ERPVHVKGFGAFGYFQTIYPMSEHTKLSFLQHSNEKVPVMVRFSLAVSTKGTPDTARNVR
HCCCCEEEECCHHHHHHHCCCCCCCCHHHHHCCCCCCEEEEEEEEEEECCCCCHHHHCCC
GFSTKFYTKEGIFDLLCNHIPVFSVRDPMRFPETIQALSPSPKNNLLDPNRFWSFVARAP
CCCEEHCCHHHHHHHHHCCCCEEECCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHCC
ESIHFVVRLYSDNGTAKSLRRIPGHSVNTYVWRNAEGNRKYVKYHWYPFEGVQFITSEEA
CCEEEEEEEECCCCHHHHHHHCCCCCCCEEEEECCCCCCEEEEEEEECCCCEEEEECHHH
NKLAAENPDYSGKDLYDAIANGKPVEYGLYVQLMDPKDETHLSYDPLDDTKIWDEKAYPL
HHHHCCCCCCCCHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
IPVGKMVLNKNPENYMEQVEKVAFSPSNLLDGAELSDDKMLQGRANIYSDSQRRRIGPEF
CCCCHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCHHHCCCCHHHHCCHHH
RKLAINQQQDWTPANQITSGDGRYVEGKLERTSIPKQDDFTQAGEFYAKLKLIEKEHLAE
HHHHCCCCCCCCCHHCCCCCCCCEEECEEHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
NLASDLKVISDDIRKVVLGYFHKVSADLVKRIETEIEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GENHDKQRQSLLGKDFNEIGERNEQAILHSQTVGSRGPVLEQDSVLHEALQEFIHEKIL
CCCHHHHHHHHHCCCHHHHCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
ERPVHVKGFGAFGYFQTIYPMSEHTKLSFLQHSNEKVPVMVRFSLAVSTKGTPDTARNVR
HCCCCEEEECCHHHHHHHCCCCCCCCHHHHHCCCCCCEEEEEEEEEEECCCCCHHHHCCC
GFSTKFYTKEGIFDLLCNHIPVFSVRDPMRFPETIQALSPSPKNNLLDPNRFWSFVARAP
CCCEEHCCHHHHHHHHHCCCCEEECCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHCC
ESIHFVVRLYSDNGTAKSLRRIPGHSVNTYVWRNAEGNRKYVKYHWYPFEGVQFITSEEA
CCEEEEEEEECCCCHHHHHHHCCCCCCCEEEEECCCCCCEEEEEEEECCCCEEEEECHHH
NKLAAENPDYSGKDLYDAIANGKPVEYGLYVQLMDPKDETHLSYDPLDDTKIWDEKAYPL
HHHHCCCCCCCCHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
IPVGKMVLNKNPENYMEQVEKVAFSPSNLLDGAELSDDKMLQGRANIYSDSQRRRIGPEF
CCCCHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCHHHCCCCHHHHCCHHH
RKLAINQQQDWTPANQITSGDGRYVEGKLERTSIPKQDDFTQAGEFYAKLKLIEKEHLAE
HHHHCCCCCCCCCHHCCCCCCCCEEECEEHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
NLASDLKVISDDIRKVVLGYFHKVSADLVKRIETEIEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377 [H]