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The map label for this gene is 52142442

Identifier: 52142442

GI number: 52142442

Start: 2915706

End: 2916338

Strand: Direct

Name: 52142442

Synonym: BCZK2800

Alternate gene names: NA

Gene position: 2915706-2916338 (Clockwise)

Preceding gene: 52142443

Following gene: 52142439

Centisome position: 55.0

GC content: 33.49

Gene sequence:

>633_bases
GTGTTCAAAATCGATAACATAAGCAGCGAATTTTTAAAACAATATTACGATAGTCGAGTCTGGTTATATGATACACATTG
GCTCGGGGTTCCCATTTCCAAACTTCCCTCTGACCTTTTTTTGTATCAAGAAATGATTCACGAATTAAAACCCGATTTAA
TTATTGAATGTGGAACCTTTTACGGTGGTAGTGCACTGTATTTAGCTTCTATATTAGATTTAATTGGAAAAGGACACGTT
TTGACTATCGATATATTTCCACAACAAAATCGTCCATCCCATGATCGTATTACGTATTTAACAGCTTCTTCTGTTTCAGT
AACCGCTGTGCAAACAATATTAAGTATGCGTAAACCTGATGATGTGATTTTAGTTATTTTAGATTCAGATCATAGTAAAG
AGCATGTAGCAAAAGAACTGTTGCTTTATCAATCTATCGTAACCACTGGTAGTTATATGATTGTAGAAGATACATCTATT
AATGGAAATCCTGTTTCTCCTGATTGGGGGCCTGGCCCAATGGAAGCTGTTGAAGAGTTTTTAGCTACAAACAACAATTT
CATAATTGATGAATCTAAACATAAATTTTTCATATCATTTAACCCAAAAGGTTTTTTAAAGAAGATAAAGTGA

Upstream 100 bases:

>100_bases
TGGTTTTTTAATGAGGTATTTTGCTCATTTTTATTAAAAAACATTCTCCTTATAGTTATATTTCACATAATATACTGTAC
AACTTTCGTTTCAGAAAGGA

Downstream 100 bases:

>100_bases
AACTTTAATAAGTGGGGTTTCCTAACTCCCCACTTATTTGATGATCTTCATTTTTGAAAAAGGATAATATACAAATTCCA
CTTTGCCTATTATATTATCT

Product: cephalosporin hydroxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MFKIDNISSEFLKQYYDSRVWLYDTHWLGVPISKLPSDLFLYQEMIHELKPDLIIECGTFYGGSALYLASILDLIGKGHV
LTIDIFPQQNRPSHDRITYLTASSVSVTAVQTILSMRKPDDVILVILDSDHSKEHVAKELLLYQSIVTTGSYMIVEDTSI
NGNPVSPDWGPGPMEAVEEFLATNNNFIIDESKHKFFISFNPKGFLKKIK

Sequences:

>Translated_210_residues
MFKIDNISSEFLKQYYDSRVWLYDTHWLGVPISKLPSDLFLYQEMIHELKPDLIIECGTFYGGSALYLASILDLIGKGHV
LTIDIFPQQNRPSHDRITYLTASSVSVTAVQTILSMRKPDDVILVILDSDHSKEHVAKELLLYQSIVTTGSYMIVEDTSI
NGNPVSPDWGPGPMEAVEEFLATNNNFIIDESKHKFFISFNPKGFLKKIK
>Mature_210_residues
MFKIDNISSEFLKQYYDSRVWLYDTHWLGVPISKLPSDLFLYQEMIHELKPDLIIECGTFYGGSALYLASILDLIGKGHV
LTIDIFPQQNRPSHDRITYLTASSVSVTAVQTILSMRKPDDVILVILDSDHSKEHVAKELLLYQSIVTTGSYMIVEDTSI
NGNPVSPDWGPGPMEAVEEFLATNNNFIIDESKHKFFISFNPKGFLKKIK

Specific function: Catalyzes the O-methylation of the hydroxyl group located on C-2 of the first rhamnosyl residue linked to the phenolic group of glycosylated phenolphthiocerol dimycocerosates (PGL) and p-hydroxybenzoic acid derivatives (p-HBAD) [H]

COG id: COG3510

COG function: function code V; Cephalosporin hydroxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rhamnosyl O-methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007072 [H]

Pfam domain/function: PF04989 CmcI [H]

EC number: NA

Molecular weight: Translated: 23833; Mature: 23833

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKIDNISSEFLKQYYDSRVWLYDTHWLGVPISKLPSDLFLYQEMIHELKPDLIIECGTF
CCEECCCHHHHHHHHHCCEEEEEECCCCCCCHHHCCHHHHHHHHHHHHCCCCEEEEECCC
YGGSALYLASILDLIGKGHVLTIDIFPQQNRPSHDRITYLTASSVSVTAVQTILSMRKPD
CCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCC
DVILVILDSDHSKEHVAKELLLYQSIVTTGSYMIVEDTSINGNPVSPDWGPGPMEAVEEF
CEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHH
LATNNNFIIDESKHKFFISFNPKGFLKKIK
HHCCCCEEEECCCCEEEEEECCCHHHHCCC
>Mature Secondary Structure
MFKIDNISSEFLKQYYDSRVWLYDTHWLGVPISKLPSDLFLYQEMIHELKPDLIIECGTF
CCEECCCHHHHHHHHHCCEEEEEECCCCCCCHHHCCHHHHHHHHHHHHCCCCEEEEECCC
YGGSALYLASILDLIGKGHVLTIDIFPQQNRPSHDRITYLTASSVSVTAVQTILSMRKPD
CCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCC
DVILVILDSDHSKEHVAKELLLYQSIVTTGSYMIVEDTSINGNPVSPDWGPGPMEAVEEF
CEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHH
LATNNNFIIDESKHKFFISFNPKGFLKKIK
HHCCCCEEEECCCCEEEEEECCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]