| Definition | Bacillus cereus E33L, complete genome. |
|---|---|
| Accession | NC_006274 |
| Length | 5,300,915 |
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The map label for this gene is fabG [H]
Identifier: 52141703
GI number: 52141703
Start: 3676406
End: 3677119
Strand: Reverse
Name: fabG [H]
Synonym: BCZK3545
Alternate gene names: 52141703
Gene position: 3677119-3676406 (Counterclockwise)
Preceding gene: 52141701
Following gene: 52141702
Centisome position: 69.37
GC content: 38.8
Gene sequence:
>714_bases ATGAAAAAGTATGCATTAGTAACTGGAGGAAGCGGAGGGATTGGCTCTGCTATTTCAAAACAATTAATTCAAGATGGATA TACAGTATATGTTCATTATAATAACAGTGAAGAGAAAGTGAATGAGTTGCAGAAAGAATCGGGTGAAGTAATTCCTGTTC AAGCGAATTTAGCTTCTACTGATGGGGCAGAGCAATTGTGGAAACAAATTGAACATCCGCTTGATGTTATCGTATATGCA GCTGGGAAGAGTATTTTTGGACTCGTAACAGATGTAACGAACGATGAATTGAATGATATGGTAGAACTTCAAGTGAAGAG TATCTATAAATTATTATCGATGGCATTGCCATCTATGATTCAACGGAGAAGCGGTAATATTGTACTTGTTTCGTCTATAT GGGGACAAATTGGCGCGTCCTGTGAAGTGCTTTACTCGATGGTAAAAGGTGCGCAAAATTCATATGTGAAAGCTTTAGCA AAAGAGGTTTCATTAAGTGGAATAAGAGCAAACGCGGTGGCGCCAGGTGCAATTGAAACGGAAATGTTAAACGTATTTTC AGAAGAGGATAAGAATGAAATTGCGGAAGAGATTCCGTTAGGACGATTAGGATTACCGGAAGAAGTAGCAAAAACTGTGT CATTTCTCGTATCACCAGGTGCATCTTATATAACTGGACAAATTATCGGAGTAAATGGCGGGTGGCATTGCTAA
Upstream 100 bases:
>100_bases GTTTTATAATAATACCCTCATCTTATCATTGATAAATTGTAAGATGAGGGTATTATTTATTTGTAGGGAAACGATTTTTT TGAGATAAGAGAGGAATTGT
Downstream 100 bases:
>100_bases AAATTTCTTACATAAAAAATGAAAAACTGTACAAATTAAGCATGATTCTATTACTAAGTAGTGAGGTGCTTACACATGTC AGTTTTAGATAATTTTGATC
Product: 3-ketoacyl-(acyl-carrier-protein) reductase
Products: 3-oxoacyl-[acyl-carrier protein]; NADPH; H+
Alternate protein names: NA
Number of amino acids: Translated: 237; Mature: 237
Protein sequence:
>237_residues MKKYALVTGGSGGIGSAISKQLIQDGYTVYVHYNNSEEKVNELQKESGEVIPVQANLASTDGAEQLWKQIEHPLDVIVYA AGKSIFGLVTDVTNDELNDMVELQVKSIYKLLSMALPSMIQRRSGNIVLVSSIWGQIGASCEVLYSMVKGAQNSYVKALA KEVSLSGIRANAVAPGAIETEMLNVFSEEDKNEIAEEIPLGRLGLPEEVAKTVSFLVSPGASYITGQIIGVNGGWHC
Sequences:
>Translated_237_residues MKKYALVTGGSGGIGSAISKQLIQDGYTVYVHYNNSEEKVNELQKESGEVIPVQANLASTDGAEQLWKQIEHPLDVIVYA AGKSIFGLVTDVTNDELNDMVELQVKSIYKLLSMALPSMIQRRSGNIVLVSSIWGQIGASCEVLYSMVKGAQNSYVKALA KEVSLSGIRANAVAPGAIETEMLNVFSEEDKNEIAEEIPLGRLGLPEEVAKTVSFLVSPGASYITGQIIGVNGGWHC >Mature_237_residues MKKYALVTGGSGGIGSAISKQLIQDGYTVYVHYNNSEEKVNELQKESGEVIPVQANLASTDGAEQLWKQIEHPLDVIVYA AGKSIFGLVTDVTNDELNDMVELQVKSIYKLLSMALPSMIQRRSGNIVLVSSIWGQIGASCEVLYSMVKGAQNSYVKALA KEVSLSGIRANAVAPGAIETEMLNVFSEEDKNEIAEEIPLGRLGLPEEVAKTVSFLVSPGASYITGQIIGVNGGWHC
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI40254992, Length=242, Percent_Identity=35.1239669421488, Blast_Score=111, Evalue=5e-25, Organism=Homo sapiens, GI32483357, Length=241, Percent_Identity=33.6099585062241, Blast_Score=109, Evalue=2e-24, Organism=Homo sapiens, GI5031737, Length=240, Percent_Identity=35, Blast_Score=102, Evalue=4e-22, Organism=Homo sapiens, GI15277342, Length=245, Percent_Identity=31.0204081632653, Blast_Score=101, Evalue=6e-22, Organism=Homo sapiens, GI66933014, Length=207, Percent_Identity=29.951690821256, Blast_Score=93, Evalue=2e-19, Organism=Homo sapiens, GI19923817, Length=245, Percent_Identity=28.9795918367347, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI7705925, Length=239, Percent_Identity=27.6150627615063, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI126723750, Length=244, Percent_Identity=27.4590163934426, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI59889578, Length=168, Percent_Identity=34.5238095238095, Blast_Score=76, Evalue=2e-14, Organism=Homo sapiens, GI33667109, Length=190, Percent_Identity=33.1578947368421, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI10190704, Length=245, Percent_Identity=24.4897959183673, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI109715829, Length=241, Percent_Identity=26.5560165975104, Blast_Score=69, Evalue=3e-12, Organism=Escherichia coli, GI1787335, Length=240, Percent_Identity=32.5, Blast_Score=130, Evalue=5e-32, Organism=Escherichia coli, GI87082100, Length=246, Percent_Identity=31.7073170731707, Blast_Score=111, Evalue=5e-26, Organism=Escherichia coli, GI2367175, Length=244, Percent_Identity=34.0163934426229, Blast_Score=108, Evalue=3e-25, Organism=Escherichia coli, GI2367365, Length=234, Percent_Identity=27.7777777777778, Blast_Score=94, Evalue=6e-21, Organism=Escherichia coli, GI1788459, Length=245, Percent_Identity=30.2040816326531, Blast_Score=92, Evalue=3e-20, Organism=Escherichia coli, GI1789378, Length=245, Percent_Identity=29.3877551020408, Blast_Score=91, Evalue=5e-20, Organism=Escherichia coli, GI87082160, Length=241, Percent_Identity=26.9709543568465, Blast_Score=90, Evalue=1e-19, Organism=Escherichia coli, GI1790717, Length=240, Percent_Identity=23.75, Blast_Score=86, Evalue=1e-18, Organism=Escherichia coli, GI1787905, Length=242, Percent_Identity=28.9256198347107, Blast_Score=84, Evalue=8e-18, Organism=Escherichia coli, GI1789208, Length=241, Percent_Identity=26.1410788381743, Blast_Score=78, Evalue=6e-16, Organism=Escherichia coli, GI1786812, Length=245, Percent_Identity=28.9795918367347, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1786701, Length=221, Percent_Identity=24.4343891402715, Blast_Score=61, Evalue=5e-11, Organism=Caenorhabditis elegans, GI17560676, Length=252, Percent_Identity=35.3174603174603, Blast_Score=118, Evalue=2e-27, Organism=Caenorhabditis elegans, GI17561402, Length=245, Percent_Identity=29.3877551020408, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI25147288, Length=241, Percent_Identity=28.6307053941909, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI71994604, Length=250, Percent_Identity=30.4, Blast_Score=89, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17562904, Length=257, Percent_Identity=31.5175097276265, Blast_Score=87, Evalue=7e-18, Organism=Caenorhabditis elegans, GI17555706, Length=247, Percent_Identity=29.5546558704453, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI71994600, Length=250, Percent_Identity=28.4, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17562910, Length=258, Percent_Identity=29.8449612403101, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17508651, Length=245, Percent_Identity=27.3469387755102, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17536025, Length=248, Percent_Identity=28.6290322580645, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17531453, Length=257, Percent_Identity=32.295719844358, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17560332, Length=262, Percent_Identity=30.5343511450382, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17562906, Length=262, Percent_Identity=30.1526717557252, Blast_Score=80, Evalue=7e-16, Organism=Caenorhabditis elegans, GI17562908, Length=264, Percent_Identity=31.0606060606061, Blast_Score=79, Evalue=1e-15, Organism=Caenorhabditis elegans, GI193204405, Length=260, Percent_Identity=28.8461538461538, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17536651, Length=248, Percent_Identity=27.8225806451613, Blast_Score=77, Evalue=6e-15, Organism=Caenorhabditis elegans, GI17561272, Length=209, Percent_Identity=24.8803827751196, Blast_Score=77, Evalue=8e-15, Organism=Caenorhabditis elegans, GI17551412, Length=260, Percent_Identity=29.6153846153846, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI72000259, Length=254, Percent_Identity=27.1653543307087, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17508895, Length=242, Percent_Identity=23.9669421487603, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17544670, Length=262, Percent_Identity=26.7175572519084, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI115534694, Length=242, Percent_Identity=27.2727272727273, Blast_Score=74, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17538480, Length=260, Percent_Identity=28.8461538461538, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI17563726, Length=254, Percent_Identity=28.740157480315, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI17560220, Length=259, Percent_Identity=26.6409266409266, Blast_Score=70, Evalue=9e-13, Organism=Caenorhabditis elegans, GI17538486, Length=261, Percent_Identity=28.735632183908, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17559104, Length=269, Percent_Identity=25.2788104089219, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17562990, Length=260, Percent_Identity=28.4615384615385, Blast_Score=67, Evalue=7e-12, Organism=Caenorhabditis elegans, GI17560150, Length=260, Percent_Identity=28.0769230769231, Blast_Score=65, Evalue=4e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=253, Percent_Identity=27.6679841897233, Blast_Score=81, Evalue=2e-16, Organism=Saccharomyces cerevisiae, GI6323882, Length=233, Percent_Identity=27.0386266094421, Blast_Score=66, Evalue=4e-12, Organism=Saccharomyces cerevisiae, GI6320089, Length=189, Percent_Identity=26.4550264550265, Blast_Score=63, Evalue=4e-11, Organism=Drosophila melanogaster, GI21355319, Length=242, Percent_Identity=36.3636363636364, Blast_Score=115, Evalue=2e-26, Organism=Drosophila melanogaster, GI24639444, Length=242, Percent_Identity=32.6446280991736, Blast_Score=114, Evalue=5e-26, Organism=Drosophila melanogaster, GI28571526, Length=250, Percent_Identity=31.2, Blast_Score=90, Evalue=2e-18, Organism=Drosophila melanogaster, GI23397609, Length=243, Percent_Identity=28.3950617283951, Blast_Score=89, Evalue=4e-18, Organism=Drosophila melanogaster, GI24644339, Length=252, Percent_Identity=28.5714285714286, Blast_Score=86, Evalue=2e-17, Organism=Drosophila melanogaster, GI21357041, Length=249, Percent_Identity=29.3172690763052, Blast_Score=82, Evalue=2e-16, Organism=Drosophila melanogaster, GI24643142, Length=235, Percent_Identity=28.0851063829787, Blast_Score=82, Evalue=2e-16, Organism=Drosophila melanogaster, GI24644337, Length=178, Percent_Identity=33.7078651685393, Blast_Score=75, Evalue=4e-14, Organism=Drosophila melanogaster, GI24640442, Length=194, Percent_Identity=29.3814432989691, Blast_Score=65, Evalue=3e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.1.1.100
Molecular weight: Translated: 25450; Mature: 25450
Theoretical pI: Translated: 4.60; Mature: 4.60
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 2.5 %Met (Translated Protein) 3.4 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 2.5 %Met (Mature Protein) 3.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKKYALVTGGSGGIGSAISKQLIQDGYTVYVHYNNSEEKVNELQKESGEVIPVQANLAST CCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCCEEEEECCCCCC DGAEQLWKQIEHPLDVIVYAAGKSIFGLVTDVTNDELNDMVELQVKSIYKLLSMALPSMI CCHHHHHHHHCCCHHEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH QRRSGNIVLVSSIWGQIGASCEVLYSMVKGAQNSYVKALAKEVSLSGIRANAVAPGAIET HHCCCCEEEEECHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHH EMLNVFSEEDKNEIAEEIPLGRLGLPEEVAKTVSFLVSPGASYITGQIIGVNGGWHC HHHHHHHHCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCC >Mature Secondary Structure MKKYALVTGGSGGIGSAISKQLIQDGYTVYVHYNNSEEKVNELQKESGEVIPVQANLAST CCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCCEEEEECCCCCC DGAEQLWKQIEHPLDVIVYAAGKSIFGLVTDVTNDELNDMVELQVKSIYKLLSMALPSMI CCHHHHHHHHCCCHHEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH QRRSGNIVLVSSIWGQIGASCEVLYSMVKGAQNSYVKALAKEVSLSGIRANAVAPGAIET HHCCCCEEEEECHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHH EMLNVFSEEDKNEIAEEIPLGRLGLPEEVAKTVSFLVSPGASYITGQIIGVNGGWHC HHHHHHHHCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NADPH [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: (3R)-3-hydroxyacyl-[acyl-carrier protein]; NADP+
Specific reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+
General reaction: Redox reaction [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9384377 [H]