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The map label for this gene is dapG [H]

Identifier: 52141688

GI number: 52141688

Start: 3693029

End: 3694261

Strand: Reverse

Name: dapG [H]

Synonym: BCZK3559

Alternate gene names: 52141688

Gene position: 3694261-3693029 (Counterclockwise)

Preceding gene: 52141687

Following gene: 52141690

Centisome position: 69.69

GC content: 39.17

Gene sequence:

>1233_bases
ATGAAAATTATTGTTCAAAAATTTGGTGGCACATCTGTACGTGATGAAAATGGACGTAAGCATGCGCTTCATCATATAAA
AAAATCGCTAGATGCGGGTTATAAAGTAGTTACTGTTGTATCTGCTATGGGCCGTAAAGGTGAACCATATGCAACGGATA
CGTTGTTAAGTCTTGTAAATCAAGAGGAATCTCATATTTCTAATCGTGAGCAAGATTTATTATTATCATGCGGAGAATTA
ATCTCAGCAATCGTCTTCTCTAATATGTTAAATGAGAACGGTATAAAAGCAGCAGCGTTAAATGGTGCACAAGCTGGTTT
TGTAACAAATGATGATTTTACGAATGCTAAGATTATTGAAATGAATTGCGATCGTATACATGAAGAGTTAGAAAATATAG
ATGTAATCGTCGTTACAGGATTCCAAGGGCAAACGAAAAAAGGTGATACGACAACACTTGGACGCGGAGGTAGTGATACT
TCAGCTTCAGCGTTAGGTGTTGCGCTTCATGCTGAATATATCGATATCTTCACAGATGTAGAAGGTGTGATGACTGCAGA
TCCTCGTATCGTAAAAGATGCACGTCATCTTCAAACTGTAACGTATAACGAAATTTGTAACATGGCTTACCAAGGTGCAA
AAGTCGTTCATCCACGTGCGGTTGAAATTGCGATGCATGCAAAAGTGCCGCTTCGTGTACGTTCTACGTATTCTGATAGT
GAGGGTACGCTTATTGCAGCATACGATGGTGCTACGAAAGGGCAGGATGTAGAAGAACGTCCGGTTACAGGTATTGCCCA
CGTATCAAATGTAACGCAAATTAAAGTGCTTGAAAAAGAAACGGCATACGATATACAGCAACATGTATTTAAAGAAATGG
CAAACGAAGGCATTAGTGTTGATTTAATTAACATTTCTCCTACTGGTGTAGCTTACACAGTAAACGATAATGTATCAGCT
CGTGCTGTTGAAGTGCTAAAACAACTTGGATATGAGCCAATTGTGACAGAACATTGCGCGAAAGTATCTATCGTTGGAGC
TGGAATGGCAGGCATCCCAGGGGTTACTGCGAAAATCGTTACAGCTTTAGCTGAAAAAGGTATTCAAATTCTGCAATCAG
CAGATAGTCATACGACAATTTGGGTTCTTGTAAAAGAAACCGATTTAGTGGAGGCTGTAAATGCATTACATAGTGCGTTT
GAGCTTTCAAAAGAAAAGCAACTGGAACAATAA

Upstream 100 bases:

>100_bases
CTGATAACTTATTAAAAGGCGCTGCATGGAATTCTGTTCAAATTGCAGAGCGCTTAGTAAAATTACAATTAGTGTAAACG
GCTAAGAGAAGGTGCAAAAT

Downstream 100 bases:

>100_bases
GGAGTGAGACCATGATAGATTTTGGGACAATTGCAACCGCGATGGTAACACCGTTTGATATAAACGGTAATATCGATTTT
GCAAAGACAACGAAATTGGT

Product: aspartate kinase I

Products: NA

Alternate protein names: Aspartate kinase 1; Aspartokinase I [H]

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MKIIVQKFGGTSVRDENGRKHALHHIKKSLDAGYKVVTVVSAMGRKGEPYATDTLLSLVNQEESHISNREQDLLLSCGEL
ISAIVFSNMLNENGIKAAALNGAQAGFVTNDDFTNAKIIEMNCDRIHEELENIDVIVVTGFQGQTKKGDTTTLGRGGSDT
SASALGVALHAEYIDIFTDVEGVMTADPRIVKDARHLQTVTYNEICNMAYQGAKVVHPRAVEIAMHAKVPLRVRSTYSDS
EGTLIAAYDGATKGQDVEERPVTGIAHVSNVTQIKVLEKETAYDIQQHVFKEMANEGISVDLINISPTGVAYTVNDNVSA
RAVEVLKQLGYEPIVTEHCAKVSIVGAGMAGIPGVTAKIVTALAEKGIQILQSADSHTTIWVLVKETDLVEAVNALHSAF
ELSKEKQLEQ

Sequences:

>Translated_410_residues
MKIIVQKFGGTSVRDENGRKHALHHIKKSLDAGYKVVTVVSAMGRKGEPYATDTLLSLVNQEESHISNREQDLLLSCGEL
ISAIVFSNMLNENGIKAAALNGAQAGFVTNDDFTNAKIIEMNCDRIHEELENIDVIVVTGFQGQTKKGDTTTLGRGGSDT
SASALGVALHAEYIDIFTDVEGVMTADPRIVKDARHLQTVTYNEICNMAYQGAKVVHPRAVEIAMHAKVPLRVRSTYSDS
EGTLIAAYDGATKGQDVEERPVTGIAHVSNVTQIKVLEKETAYDIQQHVFKEMANEGISVDLINISPTGVAYTVNDNVSA
RAVEVLKQLGYEPIVTEHCAKVSIVGAGMAGIPGVTAKIVTALAEKGIQILQSADSHTTIWVLVKETDLVEAVNALHSAF
ELSKEKQLEQ
>Mature_410_residues
MKIIVQKFGGTSVRDENGRKHALHHIKKSLDAGYKVVTVVSAMGRKGEPYATDTLLSLVNQEESHISNREQDLLLSCGEL
ISAIVFSNMLNENGIKAAALNGAQAGFVTNDDFTNAKIIEMNCDRIHEELENIDVIVVTGFQGQTKKGDTTTLGRGGSDT
SASALGVALHAEYIDIFTDVEGVMTADPRIVKDARHLQTVTYNEICNMAYQGAKVVHPRAVEIAMHAKVPLRVRSTYSDS
EGTLIAAYDGATKGQDVEERPVTGIAHVSNVTQIKVLEKETAYDIQQHVFKEMANEGISVDLINISPTGVAYTVNDNVSA
RAVEVLKQLGYEPIVTEHCAKVSIVGAGMAGIPGVTAKIVTALAEKGIQILQSADSHTTIWVLVKETDLVEAVNALHSAF
ELSKEKQLEQ

Specific function: Catalyzes 2 nonconsecutive reactions in the common biosynthetic pathway leading from Asp to diaminopimelate and Lys, to Met, and to Thr and Ile. [C]

COG id: COG0527

COG function: function code E; Aspartokinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartokinase family [H]

Homologues:

Organism=Escherichia coli, GI1786183, Length=279, Percent_Identity=34.4086021505376, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI1790455, Length=347, Percent_Identity=30.835734870317, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1790376, Length=169, Percent_Identity=31.9526627218935, Blast_Score=87, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320893, Length=393, Percent_Identity=27.4809160305344, Blast_Score=127, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR005260
- InterPro:   IPR001341
- InterPro:   IPR018042 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.2.4 [H]

Molecular weight: Translated: 44278; Mature: 44278

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS00324 ASPARTOKINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIVQKFGGTSVRDENGRKHALHHIKKSLDAGYKVVTVVSAMGRKGEPYATDTLLSLVN
CEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHC
QEESHISNREQDLLLSCGELISAIVFSNMLNENGIKAAALNGAQAGFVTNDDFTNAKIIE
CHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEECCCCCCCEEEE
MNCDRIHEELENIDVIVVTGFQGQTKKGDTTTLGRGGSDTSASALGVALHAEYIDIFTDV
ECHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
EGVMTADPRIVKDARHLQTVTYNEICNMAYQGAKVVHPRAVEIAMHAKVPLRVRSTYSDS
CCEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEEEECCCCEEEECCCCCC
EGTLIAAYDGATKGQDVEERPVTGIAHVSNVTQIKVLEKETAYDIQQHVFKEMANEGISV
CCCEEEEECCCCCCCCCCCCCCCCHHHHCCCEEEEEECHHHHHHHHHHHHHHHHCCCCEE
DLINISPTGVAYTVNDNVSARAVEVLKQLGYEPIVTEHCAKVSIVGAGMAGIPGVTAKIV
EEEEECCCCEEEEECCCCHHHHHHHHHHCCCCCHHHHHHCEEEEEECCCCCCCCHHHHHH
TALAEKGIQILQSADSHTTIWVLVKETDLVEAVNALHSAFELSKEKQLEQ
HHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIIVQKFGGTSVRDENGRKHALHHIKKSLDAGYKVVTVVSAMGRKGEPYATDTLLSLVN
CEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHC
QEESHISNREQDLLLSCGELISAIVFSNMLNENGIKAAALNGAQAGFVTNDDFTNAKIIE
CHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEECCCCCCCEEEE
MNCDRIHEELENIDVIVVTGFQGQTKKGDTTTLGRGGSDTSASALGVALHAEYIDIFTDV
ECHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
EGVMTADPRIVKDARHLQTVTYNEICNMAYQGAKVVHPRAVEIAMHAKVPLRVRSTYSDS
CCEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEEEECCCCEEEECCCCCC
EGTLIAAYDGATKGQDVEERPVTGIAHVSNVTQIKVLEKETAYDIQQHVFKEMANEGISV
CCCEEEEECCCCCCCCCCCCCCCCHHHHCCCEEEEEECHHHHHHHHHHHHHHHHCCCCEE
DLINISPTGVAYTVNDNVSARAVEVLKQLGYEPIVTEHCAKVSIVGAGMAGIPGVTAKIV
EEEEECCCCEEEEECCCCHHHHHHHHHHCCCCCHHHHHHCEEEEEECCCCCCCCHHHHHH
TALAEKGIQILQSADSHTTIWVLVKETDLVEAVNALHSAFELSKEKQLEQ
HHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8098035; 9384377 [H]