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The map label for this gene is sucC [H]

Identifier: 52141652

GI number: 52141652

Start: 3732960

End: 3734120

Strand: Reverse

Name: sucC [H]

Synonym: BCZK3595

Alternate gene names: 52141652

Gene position: 3734120-3732960 (Counterclockwise)

Preceding gene: 52141651

Following gene: 52141653

Centisome position: 70.44

GC content: 37.98

Gene sequence:

>1161_bases
ATGAATATCCATGAGTACCAAGGTAAGGCAGTCCTTAGAAGCTATGGGGTTAGCGTTCCGAACGGGAAGGTTGCATTTAC
AGTAGAAGAAGCTGTAGAAGCAGCGAAAGAATTAGGAACGGATGTATGTGTAGTAAAAGCACAAATTCACGCTGGTGGAC
GCGGCAAAGCTGGCGGAGTAAAAGTTGCAAAAAATTTAGATGAAGTTCGTACATATGCAGAGAGCATTTTAGGAACTACA
CTTGTGACACATCAAACAGGTCCTGAAGGTAAGGAAGTAAAACGCTTACTTATCGAAGAAGGTTGCGATATTAAAAAAGA
ATATTATGTAGGTCTTGTTTTAGATCGTGCAACTTCTCAAGTTGTTTTAATGGCGTCTGAAGAAGGCGGAACAGAAATTG
AAGAAGTAGCAGAAAAAACACCAGAAAAGATCTTTAAAGAATATATTGATCCAGCAGTAGGTTTACAAGGCTTCCAAGCA
CGCCGAATTGCATTTAACATCAATATTCCAAAAGAGCTTGTAGGACAAGCTGTGAAGTTTATGATGGGCTTATACCGTGC
GTTTATCGAAAAAGATTGTTCTATCGCAGAGATTAATCCACTTGTTACAACAGGTGACGGTAAAGTTATGGCATTAGATG
CGAAATTAAACTTTGATTCTAACGCTTTATATCGCCATAAAGACATTTTAGAACTTCGTGACCTTGATGAAGAAGATGCA
AAAGAAATCGAAGCTTCTAAATATGACTTAAACTACATTCCTTTAGATGGAAATATCGGTTGTATGGTTAATGGTGCAGG
TTTAGCGATGGCTACGATGGATATCATTAAACATTACCATGGAGATCCAGCTAACTTCTTAGATGTTGGTGGCGGTGCGA
CAGCTGAAAAAGTTACAGAAGCGTTTAAAATTATCCTTTCTGACAAAAATGTAAAAGGTATCTTCGTTAACATTTTTGGT
GGCATTATGAAGTGTGATGTTATTGCAGAAGGTGTTATTGAAGCAACGAAACAAGTAGGTCTTGAATTGCCTTTAGTTGT
ACGTCTTGAAGGTACAAACGTTGAGTTAGGTAAGAAAATTTTAAATGAGTCTGGCTTAAATATTGTTGCAGCAGAATCTA
TGGCAGACGGTGCACAAAAAATTGTTTCACTAGTGGGCTAA

Upstream 100 bases:

>100_bases
GTAGACAGCGTGCCAATCATCTTATACAATGGCAATGTAATGTTTTTTAAACATTAAAAAACTTTTCGAGTAAAACAGGA
AAACAGGGGAGGATGGGACC

Downstream 100 bases:

>100_bases
TAGAAAGCGGGGGAGAAAAATGAGCGTATTAGTTAATAAAGATACAAAAGTTATTGTTCAAGGTATTACAGGTTCTCAAG
GGTTATTCCACACAAAACAA

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MNIHEYQGKAVLRSYGVSVPNGKVAFTVEEAVEAAKELGTDVCVVKAQIHAGGRGKAGGVKVAKNLDEVRTYAESILGTT
LVTHQTGPEGKEVKRLLIEEGCDIKKEYYVGLVLDRATSQVVLMASEEGGTEIEEVAEKTPEKIFKEYIDPAVGLQGFQA
RRIAFNINIPKELVGQAVKFMMGLYRAFIEKDCSIAEINPLVTTGDGKVMALDAKLNFDSNALYRHKDILELRDLDEEDA
KEIEASKYDLNYIPLDGNIGCMVNGAGLAMATMDIIKHYHGDPANFLDVGGGATAEKVTEAFKIILSDKNVKGIFVNIFG
GIMKCDVIAEGVIEATKQVGLELPLVVRLEGTNVELGKKILNESGLNIVAAESMADGAQKIVSLVG

Sequences:

>Translated_386_residues
MNIHEYQGKAVLRSYGVSVPNGKVAFTVEEAVEAAKELGTDVCVVKAQIHAGGRGKAGGVKVAKNLDEVRTYAESILGTT
LVTHQTGPEGKEVKRLLIEEGCDIKKEYYVGLVLDRATSQVVLMASEEGGTEIEEVAEKTPEKIFKEYIDPAVGLQGFQA
RRIAFNINIPKELVGQAVKFMMGLYRAFIEKDCSIAEINPLVTTGDGKVMALDAKLNFDSNALYRHKDILELRDLDEEDA
KEIEASKYDLNYIPLDGNIGCMVNGAGLAMATMDIIKHYHGDPANFLDVGGGATAEKVTEAFKIILSDKNVKGIFVNIFG
GIMKCDVIAEGVIEATKQVGLELPLVVRLEGTNVELGKKILNESGLNIVAAESMADGAQKIVSLVG
>Mature_386_residues
MNIHEYQGKAVLRSYGVSVPNGKVAFTVEEAVEAAKELGTDVCVVKAQIHAGGRGKAGGVKVAKNLDEVRTYAESILGTT
LVTHQTGPEGKEVKRLLIEEGCDIKKEYYVGLVLDRATSQVVLMASEEGGTEIEEVAEKTPEKIFKEYIDPAVGLQGFQA
RRIAFNINIPKELVGQAVKFMMGLYRAFIEKDCSIAEINPLVTTGDGKVMALDAKLNFDSNALYRHKDILELRDLDEEDA
KEIEASKYDLNYIPLDGNIGCMVNGAGLAMATMDIIKHYHGDPANFLDVGGGATAEKVTEAFKIILSDKNVKGIFVNIFG
GIMKCDVIAEGVIEATKQVGLELPLVVRLEGTNVELGKKILNESGLNIVAAESMADGAQKIVSLVG

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=391, Percent_Identity=47.0588235294118, Blast_Score=359, Evalue=2e-99,
Organism=Homo sapiens, GI157779135, Length=383, Percent_Identity=46.9973890339426, Blast_Score=332, Evalue=3e-91,
Organism=Homo sapiens, GI294862256, Length=362, Percent_Identity=46.6850828729282, Blast_Score=312, Evalue=3e-85,
Organism=Escherichia coli, GI1786948, Length=385, Percent_Identity=54.5454545454545, Blast_Score=417, Evalue=1e-118,
Organism=Caenorhabditis elegans, GI17539378, Length=392, Percent_Identity=46.9387755102041, Blast_Score=350, Evalue=1e-96,
Organism=Caenorhabditis elegans, GI17567829, Length=390, Percent_Identity=45.6410256410256, Blast_Score=329, Evalue=2e-90,
Organism=Saccharomyces cerevisiae, GI6321683, Length=395, Percent_Identity=45.3164556962025, Blast_Score=348, Evalue=8e-97,
Organism=Drosophila melanogaster, GI161078106, Length=391, Percent_Identity=46.5473145780051, Blast_Score=336, Evalue=1e-92,
Organism=Drosophila melanogaster, GI24645208, Length=391, Percent_Identity=46.5473145780051, Blast_Score=336, Evalue=1e-92,
Organism=Drosophila melanogaster, GI281361397, Length=392, Percent_Identity=46.6836734693878, Blast_Score=335, Evalue=4e-92,
Organism=Drosophila melanogaster, GI281361395, Length=392, Percent_Identity=46.6836734693878, Blast_Score=335, Evalue=4e-92,
Organism=Drosophila melanogaster, GI21356231, Length=391, Percent_Identity=44.5012787723785, Blast_Score=313, Evalue=2e-85,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 41635; Mature: 41635

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS50975 ATP_GRASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEYQGKAVLRSYGVSVPNGKVAFTVEEAVEAAKELGTDVCVVKAQIHAGGRGKAGGV
CCCCHHCCHHHHHHCCCCCCCCCEEEEHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCH
KVAKNLDEVRTYAESILGTTLVTHQTGPEGKEVKRLLIEEGCDIKKEYYVGLVLDRATSQ
HHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHCCCCCCHHEEEEEEEECCCCE
VVLMASEEGGTEIEEVAEKTPEKIFKEYIDPAVGLQGFQARRIAFNINIPKELVGQAVKF
EEEEECCCCCCHHHHHHHHCHHHHHHHHCCHHCCCCCCEEEEEEEECCCCHHHHHHHHHH
MMGLYRAFIEKDCSIAEINPLVTTGDGKVMALDAKLNFDSNALYRHKDILELRDLDEEDA
HHHHHHHHHHCCCCEEECCCEEECCCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCHHHH
KEIEASKYDLNYIPLDGNIGCMVNGAGLAMATMDIIKHYHGDPANFLDVGGGATAEKVTE
HHHHHCCCCCEEEECCCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHH
AFKIILSDKNVKGIFVNIFGGIMKCDVIAEGVIEATKQVGLELPLVVRLEGTNVELGKKI
HHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHH
LNESGLNIVAAESMADGAQKIVSLVG
HCCCCCEEEEECHHHHHHHHHHHHCC
>Mature Secondary Structure
MNIHEYQGKAVLRSYGVSVPNGKVAFTVEEAVEAAKELGTDVCVVKAQIHAGGRGKAGGV
CCCCHHCCHHHHHHCCCCCCCCCEEEEHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCH
KVAKNLDEVRTYAESILGTTLVTHQTGPEGKEVKRLLIEEGCDIKKEYYVGLVLDRATSQ
HHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHCCCCCCHHEEEEEEEECCCCE
VVLMASEEGGTEIEEVAEKTPEKIFKEYIDPAVGLQGFQARRIAFNINIPKELVGQAVKF
EEEEECCCCCCHHHHHHHHCHHHHHHHHCCHHCCCCCCEEEEEEEECCCCHHHHHHHHHH
MMGLYRAFIEKDCSIAEINPLVTTGDGKVMALDAKLNFDSNALYRHKDILELRDLDEEDA
HHHHHHHHHHCCCCEEECCCEEECCCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCHHHH
KEIEASKYDLNYIPLDGNIGCMVNGAGLAMATMDIIKHYHGDPANFLDVGGGATAEKVTE
HHHHHCCCCCEEEECCCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHH
AFKIILSDKNVKGIFVNIFGGIMKCDVIAEGVIEATKQVGLELPLVVRLEGTNVELGKKI
HHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHH
LNESGLNIVAAESMADGAQKIVSLVG
HCCCCCEEEEECHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA