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The map label for this gene is recG [H]

Identifier: 52141640

GI number: 52141640

Start: 3750199

End: 3752247

Strand: Reverse

Name: recG [H]

Synonym: BCZK3614

Alternate gene names: 52141640

Gene position: 3752247-3750199 (Counterclockwise)

Preceding gene: 52141641

Following gene: 52141639

Centisome position: 70.78

GC content: 39.78

Gene sequence:

>2049_bases
TTGAATGAAGTTGTACAAGTTCCTGTTACGGATGTAAAGGGAATCGGAGGAGAAACATCTGAATTACTACACGAGATGGG
AATTTATACAGTTTCTCATCTATTAGAACATTTTCCGTACCGTTATGAAGACTATGCGATGAAAGATCTTGCTGAAGTAA
AGCATGATGAACGTGTAACAGTAGAGGGGAAAGTTCATAGTGCTCCTTTACTGCAATATTATGGGAAGAAGAAGTCGCGT
CTTACGGTTCGTGTCCTCGTAGGTCGTTATTTAATTACAGCTGTATGTTTTAATAGACCGTACTATAAGCAGAAGTTAAA
TTTAGATGAAACGGTAACGATTACTGGTAAATGGGATCAGCATCGTCAAACGATTGCGGTATCAGAACTTCATTTTGGAC
CGGTTGTACGTCAACAAGAAGTAGAGCCTGTGTACTCAGTGAAAGGGAAACTTACAGTAAAACAGATGCGCCGTTTTATT
GCACAAGCGTTAAAAGAGTATGGAGACTCTATAGTTGAAGTGTTACCTAATGGATTGCTAAGTCGATATAAATTATTGCC
GCGTTATGAAGCACTTCGGGCGTTACATTTTCCAACAGGTCAGGAAGATTTGAAGCAAGCGCGTCGCCGTTTTGTATATG
AGGAGTTTTTCTTATTTCAGTTAAAAATGCAAACGTTACGGAAAATGGAGAGGGAAAATTCGAAAGGGACGAAAAAAGAA
ATTCCTTCAGAAGAATTGCAAGAGTTTATCGATACTCTTCCGTTTCCGTTAACTGGTGCGCAACGCCGAGTTGTAGATGA
AATTATGAAAGATATGACATCTCCTTATCGAATGAATCGTCTGTTGCAAGGTGATGTAGGTTCTGGTAAAACGGTGGTTG
CTGCAATTGGTCTTTATGCAGCAAAATTAGCGCATTATCAAGGTGCTTTAATGGTTCCAACAGAAATTTTAGCAGAACAA
CATTATCAATCGCTCGCAGAGACGTTCTCGCACTTTGGTATGAAGGTCGAATTGTTAACAAGTTCAGTGAAAGGTGTGAG
ACGCCGAGAGATTTTGGCAAAATTAGAACAAGGAGAAATAGATATTCTTGTTGGGACACACGCTTTAATTCAAGATGAAG
TTATCTTTCATAGGTTAGGTCTCGTTATTACTGATGAACAACATCGATTTGGTGTAGCGCAGCGACGAGTTTTACGTGAG
AAAGGCGAGAGTCCAGACGTATTATTTATGACAGCGACTCCGATTCCGCGTACGTTAGCAATTACTGCATTTGGAGAGAT
GGATGTTTCTATAATCGATGAGATGCCAGCTGGTAGAAAGGTAATTGAAACATACTGGGCAAAACATGACATGTTAGATC
GTGTTCTCGGTTTTGTAGAGAAAGAGATAAACAAAGGAAGACAAGCATATGTTATTTGTCCCCTTATTGAAGAATCTGAG
AAACTGGATGTACAAAATGCAATCGACTTACATAGTATGCTGACTCATCATTATCAGGGTAAATGTCAAGTTGGATTAAT
GCATGGAAGATTATCATCTCAAGAAAAAGAAGAGATAATGGGACAATTTAGTGAAAATAAAGTGCAAATTCTTGTATCGA
CAACAGTTGTTGAAGTAGGTGTGAACGTACCGAATGCGACTGTAATGGTTATTTATGATGCAGAGCGTTTCGGTTTATCG
CAGCTTCATCAGCTAAGAGGACGTGTTGGGCGTGGTAGTGAACAATCGTATTGTTTATTAATCGCGGATCCAAAATCGGA
AACTGGAAAAGAACGAATGCGTATTATGACCGAAACGAATGATGGATTTGTATTGTCGGAAAAAGATTTAGAGTTAAGAG
GTCCTGGAGATTTCTTTGGGAGTAAGCAAAGTGGTTTACCAGAATTCAAGGTTGCTGATATGGTACATGATTATCGGGCG
TTAGAAACAGCTAGGCAAGATGCGGCGTTACTAGTAGATTCAGAAGCGTTTTGGCATAATGATCAATATGCGTCGTTGCG
TACGTATCTTGACGGGACAGGTGTGTTCCAGGGAGAGAAGCTCGATTAA

Upstream 100 bases:

>100_bases
TGCCTATGATAGAATATATAGGGTGAAAGAGAGCGATTACAGATGTCAATCATGTTAATGGATAATGAATCAAAAAATAA
TGTGACGGAGCGTGAGAATC

Downstream 100 bases:

>100_bases
AGGGAGGCAACAAAAGTTTTTGTTGCATTCTACTTTTAATGATTATATACTACTGTTAGTACCTAGTCATAAAAATGGAT
GGTGCGGTATGAAAAAAAGA

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 682; Mature: 682

Protein sequence:

>682_residues
MNEVVQVPVTDVKGIGGETSELLHEMGIYTVSHLLEHFPYRYEDYAMKDLAEVKHDERVTVEGKVHSAPLLQYYGKKKSR
LTVRVLVGRYLITAVCFNRPYYKQKLNLDETVTITGKWDQHRQTIAVSELHFGPVVRQQEVEPVYSVKGKLTVKQMRRFI
AQALKEYGDSIVEVLPNGLLSRYKLLPRYEALRALHFPTGQEDLKQARRRFVYEEFFLFQLKMQTLRKMERENSKGTKKE
IPSEELQEFIDTLPFPLTGAQRRVVDEIMKDMTSPYRMNRLLQGDVGSGKTVVAAIGLYAAKLAHYQGALMVPTEILAEQ
HYQSLAETFSHFGMKVELLTSSVKGVRRREILAKLEQGEIDILVGTHALIQDEVIFHRLGLVITDEQHRFGVAQRRVLRE
KGESPDVLFMTATPIPRTLAITAFGEMDVSIIDEMPAGRKVIETYWAKHDMLDRVLGFVEKEINKGRQAYVICPLIEESE
KLDVQNAIDLHSMLTHHYQGKCQVGLMHGRLSSQEKEEIMGQFSENKVQILVSTTVVEVGVNVPNATVMVIYDAERFGLS
QLHQLRGRVGRGSEQSYCLLIADPKSETGKERMRIMTETNDGFVLSEKDLELRGPGDFFGSKQSGLPEFKVADMVHDYRA
LETARQDAALLVDSEAFWHNDQYASLRTYLDGTGVFQGEKLD

Sequences:

>Translated_682_residues
MNEVVQVPVTDVKGIGGETSELLHEMGIYTVSHLLEHFPYRYEDYAMKDLAEVKHDERVTVEGKVHSAPLLQYYGKKKSR
LTVRVLVGRYLITAVCFNRPYYKQKLNLDETVTITGKWDQHRQTIAVSELHFGPVVRQQEVEPVYSVKGKLTVKQMRRFI
AQALKEYGDSIVEVLPNGLLSRYKLLPRYEALRALHFPTGQEDLKQARRRFVYEEFFLFQLKMQTLRKMERENSKGTKKE
IPSEELQEFIDTLPFPLTGAQRRVVDEIMKDMTSPYRMNRLLQGDVGSGKTVVAAIGLYAAKLAHYQGALMVPTEILAEQ
HYQSLAETFSHFGMKVELLTSSVKGVRRREILAKLEQGEIDILVGTHALIQDEVIFHRLGLVITDEQHRFGVAQRRVLRE
KGESPDVLFMTATPIPRTLAITAFGEMDVSIIDEMPAGRKVIETYWAKHDMLDRVLGFVEKEINKGRQAYVICPLIEESE
KLDVQNAIDLHSMLTHHYQGKCQVGLMHGRLSSQEKEEIMGQFSENKVQILVSTTVVEVGVNVPNATVMVIYDAERFGLS
QLHQLRGRVGRGSEQSYCLLIADPKSETGKERMRIMTETNDGFVLSEKDLELRGPGDFFGSKQSGLPEFKVADMVHDYRA
LETARQDAALLVDSEAFWHNDQYASLRTYLDGTGVFQGEKLD
>Mature_682_residues
MNEVVQVPVTDVKGIGGETSELLHEMGIYTVSHLLEHFPYRYEDYAMKDLAEVKHDERVTVEGKVHSAPLLQYYGKKKSR
LTVRVLVGRYLITAVCFNRPYYKQKLNLDETVTITGKWDQHRQTIAVSELHFGPVVRQQEVEPVYSVKGKLTVKQMRRFI
AQALKEYGDSIVEVLPNGLLSRYKLLPRYEALRALHFPTGQEDLKQARRRFVYEEFFLFQLKMQTLRKMERENSKGTKKE
IPSEELQEFIDTLPFPLTGAQRRVVDEIMKDMTSPYRMNRLLQGDVGSGKTVVAAIGLYAAKLAHYQGALMVPTEILAEQ
HYQSLAETFSHFGMKVELLTSSVKGVRRREILAKLEQGEIDILVGTHALIQDEVIFHRLGLVITDEQHRFGVAQRRVLRE
KGESPDVLFMTATPIPRTLAITAFGEMDVSIIDEMPAGRKVIETYWAKHDMLDRVLGFVEKEINKGRQAYVICPLIEESE
KLDVQNAIDLHSMLTHHYQGKCQVGLMHGRLSSQEKEEIMGQFSENKVQILVSTTVVEVGVNVPNATVMVIYDAERFGLS
QLHQLRGRVGRGSEQSYCLLIADPKSETGKERMRIMTETNDGFVLSEKDLELRGPGDFFGSKQSGLPEFKVADMVHDYRA
LETARQDAALLVDSEAFWHNDQYASLRTYLDGTGVFQGEKLD

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=665, Percent_Identity=39.6992481203008, Blast_Score=399, Evalue=1e-112,
Organism=Escherichia coli, GI1787357, Length=388, Percent_Identity=37.6288659793814, Blast_Score=268, Evalue=7e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 77706; Mature: 77706

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEVVQVPVTDVKGIGGETSELLHEMGIYTVSHLLEHFPYRYEDYAMKDLAEVKHDERVT
CCCEEECCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEE
VEGKVHSAPLLQYYGKKKSRLTVRVLVGRYLITAVCFNRPYYKQKLNLDETVTITGKWDQ
EECCCCCCHHHHHHCCCCCCEEHHHHHHHHHHHHHHHCCCHHHHHCCCCCEEEEECCCCC
HRQTIAVSELHFGPVVRQQEVEPVYSVKGKLTVKQMRRFIAQALKEYGDSIVEVLPNGLL
CCCEEEEEHHCCCCCCCHHCCCHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRYKLLPRYEALRALHFPTGQEDLKQARRRFVYEEFFLFQLKMQTLRKMERENSKGTKKE
HHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHC
IPSEELQEFIDTLPFPLTGAQRRVVDEIMKDMTSPYRMNRLLQGDVGSGKTVVAAIGLYA
CCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHH
AKLAHYQGALMVPTEILAEQHYQSLAETFSHFGMKVELLTSSVKGVRRREILAKLEQGEI
HHHHHHCCCEECHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHCCCCE
DILVGTHALIQDEVIFHRLGLVITDEQHRFGVAQRRVLREKGESPDVLFMTATPIPRTLA
EEEECCHHHHHHHHHHHHHCEEEECCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEE
ITAFGEMDVSIIDEMPAGRKVIETYWAKHDMLDRVLGFVEKEINKGRQAYVICPLIEESE
EEEECCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCC
KLDVQNAIDLHSMLTHHYQGKCQVGLMHGRLSSQEKEEIMGQFSENKVQILVSTTVVEVG
CCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHCCCCCEEEEEEEEEEEEEC
VNVPNATVMVIYDAERFGLSQLHQLRGRVGRGSEQSYCLLIADPKSETGKERMRIMTETN
CCCCCCEEEEEECCHHCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHEEEEECC
DGFVLSEKDLELRGPGDFFGSKQSGLPEFKVADMVHDYRALETARQDAALLVDSEAFWHN
CCEEEECCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECHHHCCC
DQYASLRTYLDGTGVFQGEKLD
CCHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MNEVVQVPVTDVKGIGGETSELLHEMGIYTVSHLLEHFPYRYEDYAMKDLAEVKHDERVT
CCCEEECCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEE
VEGKVHSAPLLQYYGKKKSRLTVRVLVGRYLITAVCFNRPYYKQKLNLDETVTITGKWDQ
EECCCCCCHHHHHHCCCCCCEEHHHHHHHHHHHHHHHCCCHHHHHCCCCCEEEEECCCCC
HRQTIAVSELHFGPVVRQQEVEPVYSVKGKLTVKQMRRFIAQALKEYGDSIVEVLPNGLL
CCCEEEEEHHCCCCCCCHHCCCHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRYKLLPRYEALRALHFPTGQEDLKQARRRFVYEEFFLFQLKMQTLRKMERENSKGTKKE
HHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHC
IPSEELQEFIDTLPFPLTGAQRRVVDEIMKDMTSPYRMNRLLQGDVGSGKTVVAAIGLYA
CCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHH
AKLAHYQGALMVPTEILAEQHYQSLAETFSHFGMKVELLTSSVKGVRRREILAKLEQGEI
HHHHHHCCCEECHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHCCCCE
DILVGTHALIQDEVIFHRLGLVITDEQHRFGVAQRRVLREKGESPDVLFMTATPIPRTLA
EEEECCHHHHHHHHHHHHHCEEEECCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEE
ITAFGEMDVSIIDEMPAGRKVIETYWAKHDMLDRVLGFVEKEINKGRQAYVICPLIEESE
EEEECCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCC
KLDVQNAIDLHSMLTHHYQGKCQVGLMHGRLSSQEKEEIMGQFSENKVQILVSTTVVEVG
CCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHCCCCCEEEEEEEEEEEEEC
VNVPNATVMVIYDAERFGLSQLHQLRGRVGRGSEQSYCLLIADPKSETGKERMRIMTETN
CCCCCCEEEEEECCHHCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHEEEEECC
DGFVLSEKDLELRGPGDFFGSKQSGLPEFKVADMVHDYRALETARQDAALLVDSEAFWHN
CCEEEECCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECHHHCCC
DQYASLRTYLDGTGVFQGEKLD
CCHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]