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The map label for this gene is nuoA

Identifier: 52140261

GI number: 52140261

Start: 5101825

End: 5102193

Strand: Reverse

Name: nuoA

Synonym: BCZK5000

Alternate gene names: 52140261

Gene position: 5102193-5101825 (Counterclockwise)

Preceding gene: 52140260

Following gene: 52140262

Centisome position: 96.25

GC content: 37.13

Gene sequence:

>369_bases
ATGGCAAGTGTATATGAAAATAGTTATATGATCGTTTTGATTTTCTTGCTATTAGGTATATTGCTGCCGGTAGTGGCTCT
TACATTAGGAAGGATGCTGCGCCCAAATAAACCAAGTGCAGCGAAAGCGACGACGTATGAGAGCGGGATTGAGCCTTTTC
ATGATGCGAATATTCGGTTTCATGCTCGTTATTATATTTTTGCTTTATTGTTTGTCATCTTTGATGTAGAAACTTTATTT
TTATATCCATGGGCTGTTGCATATGACAACCTCGGTTTATTTGCACTGATTGAAATGCTCATCTTTGTTGTAATGTTGCT
AGTTGGATTAGCGTATGCTTGGAAAAAGAAGGTGTTACAATGGTTATAA

Upstream 100 bases:

>100_bases
GTTGCATTATTTAGAAAAATTTAAAAATAATAATTACTGCAACTAGGACATATTGTTTACTAAGTGAACTTGTTCTTAAT
TTAGGGGGGAGGGTTTCACA

Downstream 100 bases:

>100_bases
ATTTTGAGGAATTACATCCAAATGAGCGAGCGGAATTAGAACGAAATATCTTTTTTTCTACATTGGAACAGTTGAAAGGA
TGGGCGCGAAGTAATTCTTT

Product: NADH dehydrogenase subunit A

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A; NDH-1 subunit A; NUO1

Number of amino acids: Translated: 122; Mature: 121

Protein sequence:

>122_residues
MASVYENSYMIVLIFLLLGILLPVVALTLGRMLRPNKPSAAKATTYESGIEPFHDANIRFHARYYIFALLFVIFDVETLF
LYPWAVAYDNLGLFALIEMLIFVVMLLVGLAYAWKKKVLQWL

Sequences:

>Translated_122_residues
MASVYENSYMIVLIFLLLGILLPVVALTLGRMLRPNKPSAAKATTYESGIEPFHDANIRFHARYYIFALLFVIFDVETLF
LYPWAVAYDNLGLFALIEMLIFVVMLLVGLAYAWKKKVLQWL
>Mature_121_residues
ASVYENSYMIVLIFLLLGILLPVVALTLGRMLRPNKPSAAKATTYESGIEPFHDANIRFHARYYIFALLFVIFDVETLFL
YPWAVAYDNLGLFALIEMLIFVVMLLVGLAYAWKKKVLQWL

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translo

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family

Homologues:

Organism=Escherichia coli, GI1788625, Length=108, Percent_Identity=36.1111111111111, Blast_Score=74, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOA_BACAN (Q81K00)

Other databases:

- EMBL:   AE016879
- EMBL:   AE017334
- EMBL:   AE017225
- RefSeq:   NP_847700.1
- RefSeq:   YP_022211.1
- RefSeq:   YP_031389.1
- EnsemblBacteria:   EBBACT00000012105
- EnsemblBacteria:   EBBACT00000018024
- EnsemblBacteria:   EBBACT00000020247
- GeneID:   1085220
- GeneID:   2819048
- GeneID:   2852776
- GenomeReviews:   AE016879_GR
- GenomeReviews:   AE017225_GR
- GenomeReviews:   AE017334_GR
- KEGG:   ban:BA_5542
- KEGG:   bar:GBAA_5542
- KEGG:   bat:BAS5150
- TIGR:   BA_5542
- TIGR:   GBAA_5542
- GeneTree:   EBGT00050000003148
- HOGENOM:   HBG605540
- OMA:   GERELTY
- ProtClustDB:   PRK07756
- BioCyc:   BANT260799:BAS5150-MONOMER
- BioCyc:   BANT261594:GBAA5542-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01394
- InterPro:   IPR023043
- InterPro:   IPR000440
- PANTHER:   PTHR11058

Pfam domain/function: PF00507 Oxidored_q4

EC number: =1.6.99.5

Molecular weight: Translated: 14024; Mature: 13893

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1bef194c)-; HASH(0x1c8145c4)-; HASH(0x1bda91a0)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASVYENSYMIVLIFLLLGILLPVVALTLGRMLRPNKPSAAKATTYESGIEPFHDANIRF
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCEEE
HARYYIFALLFVIFDVETLFLYPWAVAYDNLGLFALIEMLIFVVMLLVGLAYAWKKKVLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WL
HH
>Mature Secondary Structure 
ASVYENSYMIVLIFLLLGILLPVVALTLGRMLRPNKPSAAKATTYESGIEPFHDANIRF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCEEE
HARYYIFALLFVIFDVETLFLYPWAVAYDNLGLFALIEMLIFVVMLLVGLAYAWKKKVLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WL
HH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12721629