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The map label for this gene is speB [H]

Identifier: 52140195

GI number: 52140195

Start: 5177883

End: 5178755

Strand: Reverse

Name: speB [H]

Synonym: BCZK5066

Alternate gene names: 52140195

Gene position: 5178755-5177883 (Counterclockwise)

Preceding gene: 52140194

Following gene: 52140197

Centisome position: 97.7

GC content: 40.32

Gene sequence:

>873_bases
ATGCGTTTTGATGAAGCTTATTCAGGTAAAGTATTTATTAAAAGTCATCCAAGTTTTGAAGAGTCAGAGGTAGTTATTTA
CGGGATGCCTATGGATTGGACAGTAAGTTACCGTCCAGGATCTCGCTTTGGCCCTGCACGTATTCGTGAAGTATCAATCG
GTCTTGAAGAATATAGTCCGTATTTAGATCGTGAACTAGAAGAGGTAAAATATTTTGATGCGGGTGATATTCCATTACCA
TTTGGAAACGCACAACGCAGCTTAGACATGATTGAAGAATATGTATCAAAACTTTTAGATGCCGGTAAGTTTCCACTAGG
TCTCGGCGGTGAGCACTTAGTGTCTTGGCCAATTTTTAAGGCAATGGCAAAAAAATATCCGGATTTAGCAATCATCCATA
TGGATGCTCATACTGATTTACGTGAATCGTATGAAGGGGAGCCTTTATCCCACTCTACACCTATTCGTAAAGTGTGTGAT
TTAATTGGTCCGGAAAACGTATATTCTTTCGGAATTCGTTCTGGAATGAAGGAAGAATTTGAATGGGCGAAAGAAGTAGG
TATGAACTTATACAAATTTGACGTATTAGAACCGTTAAAAGAAGTATTGCCGAAACTTGCAGGACGCCCAGTCTATGTCA
CAATCGACATTGATGTATTAGACCCAGCTCACGCTCCAGGAACAGGAACGTTAGAAGCTGGTGGTATCACATCTAAAGAA
TTATTAGATTCCATCGTAGCAATTGCAAATTCAAATATAAATGTAGTTGGAGCAGACTTAGTAGAGGTAGCTCCTGTCTA
CGACCATAGTGATCAAACACCAGTCGCAGCAAGCAAATTCGTGCGGGAAATGCTGCTCGGTTGGGTGAAATAA

Upstream 100 bases:

>100_bases
AGAAGACCCGGTAAATCGAGAAAGAGGAGCAACTCGCTCCAAATTTGAGAAATAATGAAAGGTTGGGATACCTTAAGTTC
CACATAAGGAGGAAAAGAAT

Downstream 100 bases:

>100_bases
AAGCGGAATCGGCTCGCCCAGAATGTGAGGGGGATGGAGCTTCAGACATAGAGGCGTTTTTTGCCTCGAAGGAAGAAGCG
AAGCCACCGATCATTCTAGC

Product: agmatinase (agmatine ureohydrolase)

Products: NA

Alternate protein names: Agmatine ureohydrolase; AUH [H]

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MRFDEAYSGKVFIKSHPSFEESEVVIYGMPMDWTVSYRPGSRFGPARIREVSIGLEEYSPYLDRELEEVKYFDAGDIPLP
FGNAQRSLDMIEEYVSKLLDAGKFPLGLGGEHLVSWPIFKAMAKKYPDLAIIHMDAHTDLRESYEGEPLSHSTPIRKVCD
LIGPENVYSFGIRSGMKEEFEWAKEVGMNLYKFDVLEPLKEVLPKLAGRPVYVTIDIDVLDPAHAPGTGTLEAGGITSKE
LLDSIVAIANSNINVVGADLVEVAPVYDHSDQTPVAASKFVREMLLGWVK

Sequences:

>Translated_290_residues
MRFDEAYSGKVFIKSHPSFEESEVVIYGMPMDWTVSYRPGSRFGPARIREVSIGLEEYSPYLDRELEEVKYFDAGDIPLP
FGNAQRSLDMIEEYVSKLLDAGKFPLGLGGEHLVSWPIFKAMAKKYPDLAIIHMDAHTDLRESYEGEPLSHSTPIRKVCD
LIGPENVYSFGIRSGMKEEFEWAKEVGMNLYKFDVLEPLKEVLPKLAGRPVYVTIDIDVLDPAHAPGTGTLEAGGITSKE
LLDSIVAIANSNINVVGADLVEVAPVYDHSDQTPVAASKFVREMLLGWVK
>Mature_290_residues
MRFDEAYSGKVFIKSHPSFEESEVVIYGMPMDWTVSYRPGSRFGPARIREVSIGLEEYSPYLDRELEEVKYFDAGDIPLP
FGNAQRSLDMIEEYVSKLLDAGKFPLGLGGEHLVSWPIFKAMAKKYPDLAIIHMDAHTDLRESYEGEPLSHSTPIRKVCD
LIGPENVYSFGIRSGMKEEFEWAKEVGMNLYKFDVLEPLKEVLPKLAGRPVYVTIDIDVLDPAHAPGTGTLEAGGITSKE
LLDSIVAIANSNINVVGADLVEVAPVYDHSDQTPVAASKFVREMLLGWVK

Specific function: Catalyzes the formation of putrescine from agmatine [H]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=284, Percent_Identity=36.9718309859155, Blast_Score=182, Evalue=5e-46,
Organism=Homo sapiens, GI10947139, Length=268, Percent_Identity=25.3731343283582, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1789306, Length=275, Percent_Identity=35.6363636363636, Blast_Score=151, Evalue=5e-38,
Organism=Saccharomyces cerevisiae, GI6325146, Length=230, Percent_Identity=28.695652173913, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.11 [H]

Molecular weight: Translated: 32332; Mature: 32332

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFDEAYSGKVFIKSHPSFEESEVVIYGMPMDWTVSYRPGSRFGPARIREVSIGLEEYSP
CCCCCCCCCEEEEECCCCCCCCCEEEEECCCCEEEEECCCCCCCCHHHHHEECCHHHHCC
YLDRELEEVKYFDAGDIPLPFGNAQRSLDMIEEYVSKLLDAGKFPLGLGGEHLVSWPIFK
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
AMAKKYPDLAIIHMDAHTDLRESYEGEPLSHSTPIRKVCDLIGPENVYSFGIRSGMKEEF
HHHHHCCCEEEEEECCCCHHHHHCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHCCCHHHH
EWAKEVGMNLYKFDVLEPLKEVLPKLAGRPVYVTIDIDVLDPAHAPGTGTLEAGGITSKE
HHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCEECCCCCHHH
LLDSIVAIANSNINVVGADLVEVAPVYDHSDQTPVAASKFVREMLLGWVK
HHHHHHHHHCCCCEEEECHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRFDEAYSGKVFIKSHPSFEESEVVIYGMPMDWTVSYRPGSRFGPARIREVSIGLEEYSP
CCCCCCCCCEEEEECCCCCCCCCEEEEECCCCEEEEECCCCCCCCHHHHHEECCHHHHCC
YLDRELEEVKYFDAGDIPLPFGNAQRSLDMIEEYVSKLLDAGKFPLGLGGEHLVSWPIFK
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
AMAKKYPDLAIIHMDAHTDLRESYEGEPLSHSTPIRKVCDLIGPENVYSFGIRSGMKEEF
HHHHHCCCEEEEEECCCCHHHHHCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHCCCHHHH
EWAKEVGMNLYKFDVLEPLKEVLPKLAGRPVYVTIDIDVLDPAHAPGTGTLEAGGITSKE
HHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCEECCCCCHHH
LLDSIVAIANSNINVVGADLVEVAPVYDHSDQTPVAASKFVREMLLGWVK
HHHHHHHHHCCCCEEEECHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]