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The map label for this gene is yhdW [H]

Identifier: 51893875

GI number: 51893875

Start: 2941606

End: 2942451

Strand: Reverse

Name: yhdW [H]

Synonym: STH2737

Alternate gene names: 51893875

Gene position: 2942451-2941606 (Counterclockwise)

Preceding gene: 51893876

Following gene: 51893873

Centisome position: 82.51

GC content: 70.09

Gene sequence:

>846_bases
GTGCGGGCGCTCACCATCCGGCCGTTGCCCGACCGGCCCTTCACGGCTCCCCGGCCCGTGGTGCTGGCGCACCAGGGAGC
GTCGGGCCATGCGCCCTCCAACACCATGGAGGCCTTCCGGCTGGCCCTGGAGCAGGGGGCGGACATCCTGGAGCTGGACG
TGCACATGACCCGGGACGGCGTGGTGGTGGTCAGCCACGACGAGACCATCGACCGGATGAGCGACGGGACCGGGCTGATC
AAGGAGATGACCCTGGCCGAGCTGCGCCGGTACGACTTCGGCTACCGCTTCACGCCGGACGGCGGGCTGACTTATCCCTA
CCGGGGCAAGGGCGTCACGATCCCGACCCTGGAGGAGGTCTTGCAGGCCTTCCCGGAGGTGCCCGTGAACATCGAGATCA
AGCAGGCCGACCCGCCGATGGAGGCGCAGCTCTGGGAGCTGATCCAGCGCTACGGGGCGGAGGACCGGGTGCTGGTCGCC
TCGTTCCACGGCACCGTGGCGAAGCGGTGGCGCGACCTGGCCGGCGACCGGGTGGCCACCTCGGCCCCGGTGGAACACAT
GTACCTGGTGGCGGCGCACTACCTGTCCCACCTCGACCGGCTGTACGCCCCCGCCCACGACGCCTTCCAGGTGCCGGTGG
CCCAGAAGGCGGGGCCGCTCACGGTGCGGTTCGACACCGAACGGTTCCTGCGGATGGCCGAGCGGGTAAACGTGGCCGTT
CACTACTGGACGATCAACGACGAGGACGAGATGCGGCGGCTGTACCAGCTGGGCGCCCACGGCATCATCACCGACTACCC
CGACCGGGCGGTGAAGGTGCTGAGGGAGCTGGGGCTGCGGGACTAG

Upstream 100 bases:

>100_bases
CGGCATGTCTTCCGCGCTGATTCGCCGGACCCGCCGCCGGCCCCGCCGGTGGCCGGGCGTGCTGCTGACGTTGGCGCTCG
TGCTCGCGGCGCTGGCCGCC

Downstream 100 bases:

>100_bases
CCACCGCAGGTCTGCGCAGGTATAGGCAGAGGGCAACCCCCGGGCGGGGTTGCCCTCTCTTGCGTCTGCCCTAGAACTGG
ATCACGTCCAGCTCGAACAG

Product: glycerophosphodiester phosphodiesterase

Products: NA

Alternate protein names: Glycerophosphodiester phosphodiesterase [H]

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MRALTIRPLPDRPFTAPRPVVLAHQGASGHAPSNTMEAFRLALEQGADILELDVHMTRDGVVVVSHDETIDRMSDGTGLI
KEMTLAELRRYDFGYRFTPDGGLTYPYRGKGVTIPTLEEVLQAFPEVPVNIEIKQADPPMEAQLWELIQRYGAEDRVLVA
SFHGTVAKRWRDLAGDRVATSAPVEHMYLVAAHYLSHLDRLYAPAHDAFQVPVAQKAGPLTVRFDTERFLRMAERVNVAV
HYWTINDEDEMRRLYQLGAHGIITDYPDRAVKVLRELGLRD

Sequences:

>Translated_281_residues
MRALTIRPLPDRPFTAPRPVVLAHQGASGHAPSNTMEAFRLALEQGADILELDVHMTRDGVVVVSHDETIDRMSDGTGLI
KEMTLAELRRYDFGYRFTPDGGLTYPYRGKGVTIPTLEEVLQAFPEVPVNIEIKQADPPMEAQLWELIQRYGAEDRVLVA
SFHGTVAKRWRDLAGDRVATSAPVEHMYLVAAHYLSHLDRLYAPAHDAFQVPVAQKAGPLTVRFDTERFLRMAERVNVAV
HYWTINDEDEMRRLYQLGAHGIITDYPDRAVKVLRELGLRD
>Mature_281_residues
MRALTIRPLPDRPFTAPRPVVLAHQGASGHAPSNTMEAFRLALEQGADILELDVHMTRDGVVVVSHDETIDRMSDGTGLI
KEMTLAELRRYDFGYRFTPDGGLTYPYRGKGVTIPTLEEVLQAFPEVPVNIEIKQADPPMEAQLWELIQRYGAEDRVLVA
SFHGTVAKRWRDLAGDRVATSAPVEHMYLVAAHYLSHLDRLYAPAHDAFQVPVAQKAGPLTVRFDTERFLRMAERVNVAV
HYWTINDEDEMRRLYQLGAHGIITDYPDRAVKVLRELGLRD

Specific function: Glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to sn-glycerol 3-phosphate (G3P) and the corresponding alcohols [H]

COG id: COG0584

COG function: function code C; Glycerophosphoryl diester phosphodiesterase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GDPD domain [H]

Homologues:

Organism=Homo sapiens, GI260763876, Length=269, Percent_Identity=26.7657992565056, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI146198640, Length=266, Percent_Identity=28.1954887218045, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI260763878, Length=137, Percent_Identity=37.2262773722628, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI260763880, Length=137, Percent_Identity=37.2262773722628, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI7706617, Length=97, Percent_Identity=37.1134020618557, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1788572, Length=330, Percent_Identity=23.3333333333333, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789858, Length=120, Percent_Identity=30.8333333333333, Blast_Score=65, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17542344, Length=283, Percent_Identity=29.6819787985866, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17561436, Length=256, Percent_Identity=24.21875, Blast_Score=82, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004129
- InterPro:   IPR017946 [H]

Pfam domain/function: PF03009 GDPD [H]

EC number: =3.1.4.46 [H]

Molecular weight: Translated: 31752; Mature: 31752

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS50007 PIPLC_X_DOMAIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRALTIRPLPDRPFTAPRPVVLAHQGASGHAPSNTMEAFRLALEQGADILELDVHMTRDG
CCEEEECCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCC
VVVVSHDETIDRMSDGTGLIKEMTLAELRRYDFGYRFTPDGGLTYPYRGKGVTIPTLEEV
EEEEECCHHHHHHCCCCHHHHHHHHHHHHHHCCCCEECCCCCEECCCCCCCCCCHHHHHH
LQAFPEVPVNIEIKQADPPMEAQLWELIQRYGAEDRVLVASFHGTVAKRWRDLAGDRVAT
HHHCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHCCCCCCC
SAPVEHMYLVAAHYLSHLDRLYAPAHDAFQVPVAQKAGPLTVRFDTERFLRMAERVNVAV
CCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCEEEEECHHHHHHHHHHCEEEE
HYWTINDEDEMRRLYQLGAHGIITDYPDRAVKVLRELGLRD
EEEEECCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MRALTIRPLPDRPFTAPRPVVLAHQGASGHAPSNTMEAFRLALEQGADILELDVHMTRDG
CCEEEECCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCC
VVVVSHDETIDRMSDGTGLIKEMTLAELRRYDFGYRFTPDGGLTYPYRGKGVTIPTLEEV
EEEEECCHHHHHHCCCCHHHHHHHHHHHHHHCCCCEECCCCCEECCCCCCCCCCHHHHHH
LQAFPEVPVNIEIKQADPPMEAQLWELIQRYGAEDRVLVASFHGTVAKRWRDLAGDRVAT
HHHCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHCCCCCCC
SAPVEHMYLVAAHYLSHLDRLYAPAHDAFQVPVAQKAGPLTVRFDTERFLRMAERVNVAV
CCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCEEEEECHHHHHHHHHHCEEEE
HYWTINDEDEMRRLYQLGAHGIITDYPDRAVKVLRELGLRD
EEEEECCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]