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The map label for this gene is gtaB [H]

Identifier: 51893851

GI number: 51893851

Start: 2910367

End: 2911251

Strand: Reverse

Name: gtaB [H]

Synonym: STH2713

Alternate gene names: 51893851

Gene position: 2911251-2910367 (Counterclockwise)

Preceding gene: 51893853

Following gene: 51893850

Centisome position: 81.64

GC content: 58.42

Gene sequence:

>885_bases
GTGATGCGGGTTCGGAAGGCTGTGATCCCCGCTGCGGGTTTGGGTACGCGATTCCTGCCGGCGACCAAGGCGCAACCGAA
GGAGATGCTTCCACTCGTGGACAAGCCGATCATTCAGTACGTAGTGGAAGAGGCGGTGGCTTCCGGGATCGAGGATATCA
TTATTGTTACCAGCCGGGGAAAGCGTGCAATTGAGGACCACTTCGACCGGAATCTGGAGTTGGAACTAATGCTGGAGGGA
CGCAACGGTGAACTACTGGCCGCTGTGAGGCGACTGAGCGATATGGCCGATATCCACTTCATCCGGCAGAAGCAGCCTAT
GGGGCTTGGGCACGCGGTGTACCAGGCGCGCAGGCACGTGGGTAATGAACCATTCGCAGTACTTCTGGGGGACGAGGTTT
TCATCGGTGCCACCCCCTGCTTGAAGCAGTTGATCGACACATATGAGGAGACGGGAGGCTCGGTGATCGCGGTGCGGCCT
GTACCCCTGGAGGAGGTATCGCGTTATGGCGTGATCGCACCTGAGCCAGCGGGTGAGCGGCTCCATCGTGCCGTCGACTT
GGTAGAGAAGCCTTCGGTGACGAAGGCGCCGTCGAATCTGGCCATCGTCGGGCGTTATGTACTGGATCCAGCGATTTTCG
AGATACTGTCAGATCTGCCGCCGGGGCGGAATGGTGAGATTCAACTGACGGACGGTCTGCGGGAACTGAACCGGTTCTCT
CAGGTGTATGCCTACGAGCCAGCGGTCAAGCGGTACGACGTAGGCGAGAAGCTTGGGTTCATTCAGGCAACCATTGAATT
GGCGCTGGAGCGCAACGAATTGGCTGATGGGCTTCGGGTATACCTAGAGGATCTCGTGGCAGGCCGCCCAACTGCAAATA
CGTAA

Upstream 100 bases:

>100_bases
CATTGCACGAAGTCCGGGTTATTCACGCGAAACTTGAGCTAGGACCACCATCACGGTAAGCGAGACGGGTAGAGTTAGTC
TGGTCATAAGGAGGCGAATT

Downstream 100 bases:

>100_bases
CTGCTGAGCTGGGTTTCTGGGATGTGTCGGCCGTAACTTGGCCCTCGACTGCCATGGATTGATAGCCTACTAGACTGGCA
TCGCGTCGGAGGGGAAGTAG

Product: UTP-glucose-1-phosphate uridylyltransferase

Products: NA

Alternate protein names: Alpha-D-glucosyl-1-phosphate uridylyltransferase; General stress protein 33; GSP33; UDP-glucose pyrophosphorylase; UDPGP; Uridine diphosphoglucose pyrophosphorylase [H]

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MMRVRKAVIPAAGLGTRFLPATKAQPKEMLPLVDKPIIQYVVEEAVASGIEDIIIVTSRGKRAIEDHFDRNLELELMLEG
RNGELLAAVRRLSDMADIHFIRQKQPMGLGHAVYQARRHVGNEPFAVLLGDEVFIGATPCLKQLIDTYEETGGSVIAVRP
VPLEEVSRYGVIAPEPAGERLHRAVDLVEKPSVTKAPSNLAIVGRYVLDPAIFEILSDLPPGRNGEIQLTDGLRELNRFS
QVYAYEPAVKRYDVGEKLGFIQATIELALERNELADGLRVYLEDLVAGRPTANT

Sequences:

>Translated_294_residues
MMRVRKAVIPAAGLGTRFLPATKAQPKEMLPLVDKPIIQYVVEEAVASGIEDIIIVTSRGKRAIEDHFDRNLELELMLEG
RNGELLAAVRRLSDMADIHFIRQKQPMGLGHAVYQARRHVGNEPFAVLLGDEVFIGATPCLKQLIDTYEETGGSVIAVRP
VPLEEVSRYGVIAPEPAGERLHRAVDLVEKPSVTKAPSNLAIVGRYVLDPAIFEILSDLPPGRNGEIQLTDGLRELNRFS
QVYAYEPAVKRYDVGEKLGFIQATIELALERNELADGLRVYLEDLVAGRPTANT
>Mature_294_residues
MMRVRKAVIPAAGLGTRFLPATKAQPKEMLPLVDKPIIQYVVEEAVASGIEDIIIVTSRGKRAIEDHFDRNLELELMLEG
RNGELLAAVRRLSDMADIHFIRQKQPMGLGHAVYQARRHVGNEPFAVLLGDEVFIGATPCLKQLIDTYEETGGSVIAVRP
VPLEEVSRYGVIAPEPAGERLHRAVDLVEKPSVTKAPSNLAIVGRYVLDPAIFEILSDLPPGRNGEIQLTDGLRELNRFS
QVYAYEPAVKRYDVGEKLGFIQATIELALERNELADGLRVYLEDLVAGRPTANT

Specific function: Catalyzes the formation of UDP-glucose from glucose-1- phosphate and UTP. This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in B.subtilis membrane, which is also used as a membr

COG id: COG1210

COG function: function code M; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDPGP type 2 family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=260, Percent_Identity=27.3076923076923, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI11761619, Length=260, Percent_Identity=27.3076923076923, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1787488, Length=296, Percent_Identity=47.2972972972973, Blast_Score=225, Evalue=2e-60,
Organism=Escherichia coli, GI1788355, Length=293, Percent_Identity=40.9556313993174, Blast_Score=190, Evalue=1e-49,
Organism=Escherichia coli, GI1788351, Length=232, Percent_Identity=30.1724137931034, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1790224, Length=228, Percent_Identity=28.9473684210526, Blast_Score=83, Evalue=2e-17,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 260 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005771
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.9 [H]

Molecular weight: Translated: 32466; Mature: 32466

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRVRKAVIPAAGLGTRFLPATKAQPKEMLPLVDKPIIQYVVEEAVASGIEDIIIVTSRG
CCCHHHHHCCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHCCCCEEEEEECCC
KRAIEDHFDRNLELELMLEGRNGELLAAVRRLSDMADIHFIRQKQPMGLGHAVYQARRHV
CHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHC
GNEPFAVLLGDEVFIGATPCLKQLIDTYEETGGSVIAVRPVPLEEVSRYGVIAPEPAGER
CCCCEEEEECCEEEECCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHCCCCCCCCHHHH
LHRAVDLVEKPSVTKAPSNLAIVGRYVLDPAIFEILSDLPPGRNGEIQLTDGLRELNRFS
HHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHH
QVYAYEPAVKRYDVGEKLGFIQATIELALERNELADGLRVYLEDLVAGRPTANT
HHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MMRVRKAVIPAAGLGTRFLPATKAQPKEMLPLVDKPIIQYVVEEAVASGIEDIIIVTSRG
CCCHHHHHCCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHCCCCEEEEEECCC
KRAIEDHFDRNLELELMLEGRNGELLAAVRRLSDMADIHFIRQKQPMGLGHAVYQARRHV
CHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHC
GNEPFAVLLGDEVFIGATPCLKQLIDTYEETGGSVIAVRPVPLEEVSRYGVIAPEPAGER
CCCCEEEEECCEEEECCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHCCCCCCCCHHHH
LHRAVDLVEKPSVTKAPSNLAIVGRYVLDPAIFEILSDLPPGRNGEIQLTDGLRELNRFS
HHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHH
QVYAYEPAVKRYDVGEKLGFIQATIELALERNELADGLRVYLEDLVAGRPTANT
HHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8320212; 8126437; 9384377; 9298659 [H]