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The map label for this gene is clpP [H]

Identifier: 51599007

GI number: 51599007

Start: 802353

End: 802949

Strand: Direct

Name: clpP [H]

Synonym: BG0779

Alternate gene names: 51599007

Gene position: 802353-802949 (Clockwise)

Preceding gene: 51599000

Following gene: 51599008

Centisome position: 88.73

GC content: 32.16

Gene sequence:

>597_bases
ATGACCGGTAAAGAAGATGATAATATTTGTGTTTTGCATGATAAATCATTGGAATTAATTTTAAAGAGTAGATCAATAGT
GATTGCTGGTGAGATTACTAAGGATGTTTCTCGACTTTTTCAGGAAAAAATATTATTGTTAGAGACCTTAGATTTTAAAA
AGCCTATATTTGTGTACATTGATTCAGAAGGAGGCGATATTGATGCTGGATTTGCTATTTTCAATATGATTCGTTTTGTT
AAGCCTAAAGTTTTTACAGTTGGAGTAGGGCTTGTTGCTAGCGCTGCCGCTTTAATTTTTTTGGCTGCAAAATTAGAAAA
TAGATTTTCATTGCCTTTTGCCAGGTATTTATTGCATCAACCTTTGAGCGGATTTAAAGGAGTTGCCACAGACATTGAGA
TTTATACTAATGAGTTAAATAAAGTTAAAAAAGAGCTTAATAATATTATTTCAAAAGAAACAGGTCAAGAGATTTCTACA
ATAGAAAAGGACACTGATAGGGATTTTTGGTTAGACAGTAGTGCTGCAAAAAAGTATGGACTTGTATTTGAAGTTGTTGA
GACAAAGTGTCAACTTGAAGAGTTTATTTCTGCTTAG

Upstream 100 bases:

>100_bases
AATTATTTGCAATTGTTTAGTTTTTATACTTTTTTATAATTTAAAAACCTTTTGTTTTAAATTATAATATATCATTATGT
TTTTGTATAAGGGATGTTTT

Downstream 100 bases:

>100_bases
TGTTTTATTTTTTTCCTGTAATTTTGTAGATATAGATTTTAGTATTTTGGAGCTTAAGGTTGCAAACCTTGGTTTAAGTG
ATAATTCTTTTCAAGAATCA

Product: ATP-dependent Clp protease proteolytic subunit

Products: NA

Alternate protein names: Endopeptidase Clp 2 [H]

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MTGKEDDNICVLHDKSLELILKSRSIVIAGEITKDVSRLFQEKILLLETLDFKKPIFVYIDSEGGDIDAGFAIFNMIRFV
KPKVFTVGVGLVASAAALIFLAAKLENRFSLPFARYLLHQPLSGFKGVATDIEIYTNELNKVKKELNNIISKETGQEIST
IEKDTDRDFWLDSSAAKKYGLVFEVVETKCQLEEFISA

Sequences:

>Translated_198_residues
MTGKEDDNICVLHDKSLELILKSRSIVIAGEITKDVSRLFQEKILLLETLDFKKPIFVYIDSEGGDIDAGFAIFNMIRFV
KPKVFTVGVGLVASAAALIFLAAKLENRFSLPFARYLLHQPLSGFKGVATDIEIYTNELNKVKKELNNIISKETGQEIST
IEKDTDRDFWLDSSAAKKYGLVFEVVETKCQLEEFISA
>Mature_197_residues
TGKEDDNICVLHDKSLELILKSRSIVIAGEITKDVSRLFQEKILLLETLDFKKPIFVYIDSEGGDIDAGFAIFNMIRFVK
PKVFTVGVGLVASAAALIFLAAKLENRFSLPFARYLLHQPLSGFKGVATDIEIYTNELNKVKKELNNIISKETGQEISTI
EKDTDRDFWLDSSAAKKYGLVFEVVETKCQLEEFISA

Specific function: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins [H]

COG id: COG0740

COG function: function code OU; Protease subunit of ATP-dependent Clp proteases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S14 family [H]

Homologues:

Organism=Homo sapiens, GI5174419, Length=167, Percent_Identity=35.9281437125749, Blast_Score=121, Evalue=4e-28,
Organism=Escherichia coli, GI1786641, Length=163, Percent_Identity=41.1042944785276, Blast_Score=142, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17538017, Length=166, Percent_Identity=32.5301204819277, Blast_Score=108, Evalue=1e-24,
Organism=Drosophila melanogaster, GI20129427, Length=168, Percent_Identity=36.9047619047619, Blast_Score=125, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001907
- InterPro:   IPR018215 [H]

Pfam domain/function: PF00574 CLP_protease [H]

EC number: =3.4.21.92 [H]

Molecular weight: Translated: 22217; Mature: 22086

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00382 CLP_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGKEDDNICVLHDKSLELILKSRSIVIAGEITKDVSRLFQEKILLLETLDFKKPIFVYI
CCCCCCCCEEEEECCCCEEHEECCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
DSEGGDIDAGFAIFNMIRFVKPKVFTVGVGLVASAAALIFLAAKLENRFSLPFARYLLHQ
ECCCCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHC
PLSGFKGVATDIEIYTNELNKVKKELNNIISKETGQEISTIEKDTDRDFWLDSSAAKKYG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCEEECCHHHHHHH
LVFEVVETKCQLEEFISA
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TGKEDDNICVLHDKSLELILKSRSIVIAGEITKDVSRLFQEKILLLETLDFKKPIFVYI
CCCCCCCEEEEECCCCEEHEECCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
DSEGGDIDAGFAIFNMIRFVKPKVFTVGVGLVASAAALIFLAAKLENRFSLPFARYLLHQ
ECCCCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHC
PLSGFKGVATDIEIYTNELNKVKKELNNIISKETGQEISTIEKDTDRDFWLDSSAAKKYG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCEEECCHHHHHHH
LVFEVVETKCQLEEFISA
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9403685 [H]