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The map label for this gene is tig

Identifier: 51598862

GI number: 51598862

Start: 638527

End: 639885

Strand: Direct

Name: tig

Synonym: BG0626

Alternate gene names: 51598862

Gene position: 638527-639885 (Clockwise)

Preceding gene: 51598861

Following gene: 51598863

Centisome position: 70.61

GC content: 28.26

Gene sequence:

>1359_bases
GTGATTTTGAGTAAAGATATTAAACTTCTTCCAGGTTCGAAAGTTGAGGTTTTAATTAGAGTTTCAAAAAATATTATTCA
GGAAAAATATAAGTCGTTATTACAAGATTATTCTTCCCGACTTAAGATTCAGGGTTTTAGAATTGGAAAAGTCCCTATTA
ATATTATTGAGAATAAATATTCTGAGGGGTTAAAAGCTACTGTTTTAGAAGAAGTGATTAATGGTTCTTTTAAAGAATTT
TTCAAAGAAGAACCTAAAAGACCTTTGAGTTATGCTGCTCCTACTATAAAGGAAAAAGATTTGAGATTAGATCTTGACAA
AGATTTTGAATTTACTTTTACATATGAGACTTATCCTGAATTTGAAATTCCAAGTGTTGATAGTATTGATATTAAAGTAG
AGGTTCCTGAAGTTTTTATTGATGATTCTGATATTGATAATGAGATTAGGCGTCTTCAAATAGAAAATTCAATTATTATT
GAAGATGAGGAAGGGGTTGTCAAGAAAAATAGCATTGTTAAAGTGGATTTTGTTGAACTTGATGATCTTTTAAATGAGAT
ATTATCAACCAAAAGACAAGATTTTGTTTTTACAGTTGGAAAGTCTGAAACCTATTATGATTTTGACAGAGATGTAATTG
GCATGAGGATAAATGAGGAGAAAGTTTTAGAAAAATCTTACATTACGGATTACAAATTTGAAGAACTTGCGGGCTCTTCA
AGAAAATTAAAGATTAAAATTAAAAGTATCAAAAAAAGAGATCTCCCCTTAATAGATGATGAGTTTGCGCAAGATATTAG
CGACAGATATGATACGCTGGATGATCTTAAAAATTTTATAAGATCTGATATTTTAAACGTTATTGAAGAAAAAAAGGAAG
CTTTAAAGCTAAATAAATTTTTTTCTACTATTTCTGAAAAATTAGAAATAGATATTCCGCATTCAATGATTGAGGCTGAA
ATTGAAATTGCTTTTAAGGATACTGCAAAGCAAAATAAGATGGGGCTTGAGGAGTTTAAAAGTATTTTTTATTCTTCGGG
ATATGTTGGTAGTGTCAATTTGAAAGATAAAATTCTTAGCAATTTGAAATCTAAGTTGATAATTCAGAAAATGGTAGATT
TAGATCCAATTGAAGTTACTGAGAGTGATCTTGAGGATGAAATAGCTAGACAGTCTGAGAATTCAGGTATGAGTTGCGAG
GAGATTAAGAAATTTTATGAAGATCAAAATTTGATTTCTTATTTAAAGGATGATATTAAAAGGAAAAGAGTTAAGAAAAA
AATTTTAGCAAATCTTAAAGAGTTAAAAGGCAAGCAAGTTTCTTTTAAAGATTTTGTTAATTATAAAATTTGTGAGTAA

Upstream 100 bases:

>100_bases
CAGGGGTAGAGTGTCACCTTGCCAAGGTGGAAGTCGCGGGTTCAAATCCCGTCTTTCGCTTTTAAATAATTATCAATAAA
GTTTAATTGAGGCATTAGCA

Downstream 100 bases:

>100_bases
GAAAAATGGAGTTTATGCATAATTTAATACCCACTGTGATAGAGCATACGGGAAATTATGAGAGAGTATTTGATATATAT
TCAAGATTACTTAGAGAGCG

Product: trigger factor

Products: peptidylproline (w =0) [C]

Alternate protein names: TF

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MILSKDIKLLPGSKVEVLIRVSKNIIQEKYKSLLQDYSSRLKIQGFRIGKVPINIIENKYSEGLKATVLEEVINGSFKEF
FKEEPKRPLSYAAPTIKEKDLRLDLDKDFEFTFTYETYPEFEIPSVDSIDIKVEVPEVFIDDSDIDNEIRRLQIENSIII
EDEEGVVKKNSIVKVDFVELDDLLNEILSTKRQDFVFTVGKSETYYDFDRDVIGMRINEEKVLEKSYITDYKFEELAGSS
RKLKIKIKSIKKRDLPLIDDEFAQDISDRYDTLDDLKNFIRSDILNVIEEKKEALKLNKFFSTISEKLEIDIPHSMIEAE
IEIAFKDTAKQNKMGLEEFKSIFYSSGYVGSVNLKDKILSNLKSKLIIQKMVDLDPIEVTESDLEDEIARQSENSGMSCE
EIKKFYEDQNLISYLKDDIKRKRVKKKILANLKELKGKQVSFKDFVNYKICE

Sequences:

>Translated_452_residues
MILSKDIKLLPGSKVEVLIRVSKNIIQEKYKSLLQDYSSRLKIQGFRIGKVPINIIENKYSEGLKATVLEEVINGSFKEF
FKEEPKRPLSYAAPTIKEKDLRLDLDKDFEFTFTYETYPEFEIPSVDSIDIKVEVPEVFIDDSDIDNEIRRLQIENSIII
EDEEGVVKKNSIVKVDFVELDDLLNEILSTKRQDFVFTVGKSETYYDFDRDVIGMRINEEKVLEKSYITDYKFEELAGSS
RKLKIKIKSIKKRDLPLIDDEFAQDISDRYDTLDDLKNFIRSDILNVIEEKKEALKLNKFFSTISEKLEIDIPHSMIEAE
IEIAFKDTAKQNKMGLEEFKSIFYSSGYVGSVNLKDKILSNLKSKLIIQKMVDLDPIEVTESDLEDEIARQSENSGMSCE
EIKKFYEDQNLISYLKDDIKRKRVKKKILANLKELKGKQVSFKDFVNYKICE
>Mature_452_residues
MILSKDIKLLPGSKVEVLIRVSKNIIQEKYKSLLQDYSSRLKIQGFRIGKVPINIIENKYSEGLKATVLEEVINGSFKEF
FKEEPKRPLSYAAPTIKEKDLRLDLDKDFEFTFTYETYPEFEIPSVDSIDIKVEVPEVFIDDSDIDNEIRRLQIENSIII
EDEEGVVKKNSIVKVDFVELDDLLNEILSTKRQDFVFTVGKSETYYDFDRDVIGMRINEEKVLEKSYITDYKFEELAGSS
RKLKIKIKSIKKRDLPLIDDEFAQDISDRYDTLDDLKNFIRSDILNVIEEKKEALKLNKFFSTISEKLEIDIPHSMIEAE
IEIAFKDTAKQNKMGLEEFKSIFYSSGYVGSVNLKDKILSNLKSKLIIQKMVDLDPIEVTESDLEDEIARQSENSGMSCE
EIKKFYEDQNLISYLKDDIKRKRVKKKILANLKELKGKQVSFKDFVNYKICE

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain

Homologues:

Organism=Escherichia coli, GI1786640, Length=319, Percent_Identity=27.5862068965517, Blast_Score=119, Evalue=5e-28,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): TIG_BORGA (Q660R3)

Other databases:

- EMBL:   CP000013
- RefSeq:   YP_073050.1
- ProteinModelPortal:   Q660R3
- SMR:   Q660R3
- EnsemblBacteria:   EBBORT00000007816
- GeneID:   2957844
- GenomeReviews:   CP000013_GR
- KEGG:   bga:BG0626
- GeneTree:   EBGT00050000006990
- HOGENOM:   HBG352938
- OMA:   TERENIE
- ProtClustDB:   PRK01490
- BioCyc:   BGAR290434:BG0626-MONOMER
- HAMAP:   MF_00303
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881
- Gene3D:   G3DSA:1.10.3120.10
- Gene3D:   G3DSA:3.30.70.1050
- PIRSF:   PIRSF003095
- TIGRFAMs:   TIGR00115

Pfam domain/function: PF05698 Trigger_C; PF05697 Trigger_N; SSF109998 Trigger_fac_C_bac; SSF102735 Trigger_fac_ribosome-bd_bac

EC number: NA

Molecular weight: Translated: 52647; Mature: 52647

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILSKDIKLLPGSKVEVLIRVSKNIIQEKYKSLLQDYSSRLKIQGFRIGKVPINIIENKY
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEECCCCHHHHHHHH
SEGLKATVLEEVINGSFKEFFKEEPKRPLSYAAPTIKEKDLRLDLDKDFEFTFTYETYPE
HCCHHHHHHHHHHCCHHHHHHHHCCCCCCHHCCCCCCCCCCEEECCCCCEEEEEEECCCC
FEIPSVDSIDIKVEVPEVFIDDSDIDNEIRRLQIENSIIIEDEEGVVKKNSIVKVDFVEL
CCCCCCCCEEEEEECCEEEECCCCCHHHHHEEEECCCEEEECCCCCEECCCEEEEEHHHH
DDLLNEILSTKRQDFVFTVGKSETYYDFDRDVIGMRINEEKVLEKSYITDYKFEELAGSS
HHHHHHHHHCCCCCEEEEECCCCCEEECCCCEEEEEECHHHHHHHHHCCCCCHHHHCCCC
RKLKIKIKSIKKRDLPLIDDEFAQDISDRYDTLDDLKNFIRSDILNVIEEKKEALKLNKF
CEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSTISEKLEIDIPHSMIEAEIEIAFKDTAKQNKMGLEEFKSIFYSSGYVGSVNLKDKILS
HHHHHHHEEECCCHHHHHHHEEEEECCCCCHHCCCHHHHHHHHHCCCCEEECCHHHHHHH
NLKSKLIIQKMVDLDPIEVTESDLEDEIARQSENSGMSCEEIKKFYEDQNLISYLKDDIK
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHH
RKRVKKKILANLKELKGKQVSFKDFVNYKICE
HHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCC
>Mature Secondary Structure
MILSKDIKLLPGSKVEVLIRVSKNIIQEKYKSLLQDYSSRLKIQGFRIGKVPINIIENKY
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEECCCCHHHHHHHH
SEGLKATVLEEVINGSFKEFFKEEPKRPLSYAAPTIKEKDLRLDLDKDFEFTFTYETYPE
HCCHHHHHHHHHHCCHHHHHHHHCCCCCCHHCCCCCCCCCCEEECCCCCEEEEEEECCCC
FEIPSVDSIDIKVEVPEVFIDDSDIDNEIRRLQIENSIIIEDEEGVVKKNSIVKVDFVEL
CCCCCCCCEEEEEECCEEEECCCCCHHHHHEEEECCCEEEECCCCCEECCCEEEEEHHHH
DDLLNEILSTKRQDFVFTVGKSETYYDFDRDVIGMRINEEKVLEKSYITDYKFEELAGSS
HHHHHHHHHCCCCCEEEEECCCCCEEECCCCEEEEEECHHHHHHHHHCCCCCHHHHCCCC
RKLKIKIKSIKKRDLPLIDDEFAQDISDRYDTLDDLKNFIRSDILNVIEEKKEALKLNKF
CEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSTISEKLEIDIPHSMIEAEIEIAFKDTAKQNKMGLEEFKSIFYSSGYVGSVNLKDKILS
HHHHHHHEEECCCHHHHHHHEEEEECCCCCHHCCCHHHHHHHHHCCCCEEECCHHHHHHH
NLKSKLIIQKMVDLDPIEVTESDLEDEIARQSENSGMSCEEIKKFYEDQNLISYLKDDIK
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHH
RKRVKKKILANLKELKGKQVSFKDFVNYKICE
HHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA