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The map label for this gene is murA [H]

Identifier: 51598727

GI number: 51598727

Start: 493043

End: 494326

Strand: Direct

Name: murA [H]

Synonym: BG0484

Alternate gene names: 51598727

Gene position: 493043-494326 (Clockwise)

Preceding gene: 51598726

Following gene: 51598728

Centisome position: 54.53

GC content: 34.27

Gene sequence:

>1284_bases
ATGTATAGTTATATTGTAGAAGGTGGTTTTAAGATAGGTGGTCAAATTACAGCTAGCGGCAATAAGAATTCTGCTTTACC
TTGTATTTTAGCGGCTTTACTTACCAATGAAGATGTTATTTTAGAAAATATTCCTAATATTAATGATGTAAAAGTTGTTT
TAGATATTTTAAGTGATATAGGAGCAGATATTGTAAGAGAGGGAAATGCTTTAAAAATAAAAGTTTCAAATATTGTGAAA
ACAGAAATAGATTCCTCTTTTACGGATTTAATTAGGGCTTCCATACTTTTATTAGGACCTTTTGTCTCTAGATTTGGGGA
AATAGATATGGCGCTTCCAGGAGGAGATGTGATTGGAAAAAGGCGGCTTGATACTCATTTTTATGGCCTTTCTAAACTAG
GAGCTAAGTTAATCAACAAAGATGGAAGAATTGTTTTAAAGGCCAAAAAGCTTGTTGGAGCTGAAATGTTTTTAGATGAA
GCTTCTGTTACAGCTACAGAAAATATCATTATGGCTTCAGTTCTTGCCGAAGGGAATACTGTTATTATGAACGCTGCTTG
TGAGCCACATGTTCAAGATTTATGTAATATGTTGAATTCAATGGGTGCTAATATTTTAGGGATTGGTTCAAATGTTTTAG
AAATAAAGGGTGTAAAAAAATTAAGAGGAACCACATTTAGAATAGGTGCCGACTTCATGCAAGTTGGTTCTTTGATTAGT
CTTGCTGCATTAACAGGGGGTGAATTGGAAATTAAAAAAGCAGATCCCCAACATTTCAGATTAATTAGACATATATATTC
AAGGCTTGGTATTAATTTTGAATATGACAAGGAAAATGTATACGTAAGAGATAAACAAGAGTTAAAGGTTAAGCTAGATT
TTGGCGGACACATTCCAAAAATTGATGATGGTCCATGGCCCGCCTTTCCGACAGACCTTATGAGTATTATTATAGTCACT
GCAACTCAAGTAGAAGGCACAGTTCTTGTTTTTGAAAAAATGTTTGAATCCAGGATGTTTTTTGTAGACAAATTAATAAA
AATGGGGGCTCAAATTGTACTCTGTGATCCACACCGTGTAGTAGTTACTGGCAAATCTCCTCTTAAAGGCAATGTTTTAT
CTTCTCCAGATGTGCGGGCAGGAATGTCTCTTCTTATTGCTGCTTTTGTTGCTGAAGGTCGCAGCGAGATTCAAAATGTT
TATCAAATTGAAAGGGGATACGAAGATGTAGCTAATAAATTAATTAATTTGGGGGCAAAAATTAAGAAAGTTAAAAGTCA
ATAG

Upstream 100 bases:

>100_bases
AATTTAATTGATCTTATTAATTGATCTTATTAATTGATCTTATTAATGTGATTTAATTTTATTAATTTTCTTATATATAG
TATGTATAGGAGGGTGAGTT

Downstream 100 bases:

>100_bases
CTTGTTAATAGACTTTATTATATTTTTATTATATGTGGTTTATTGAAAATGTTTTTAAGAGAGGATAAGGTATTAGCTGA
TTGAATTGTGAATGAGAATA

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MYSYIVEGGFKIGGQITASGNKNSALPCILAALLTNEDVILENIPNINDVKVVLDILSDIGADIVREGNALKIKVSNIVK
TEIDSSFTDLIRASILLLGPFVSRFGEIDMALPGGDVIGKRRLDTHFYGLSKLGAKLINKDGRIVLKAKKLVGAEMFLDE
ASVTATENIIMASVLAEGNTVIMNAACEPHVQDLCNMLNSMGANILGIGSNVLEIKGVKKLRGTTFRIGADFMQVGSLIS
LAALTGGELEIKKADPQHFRLIRHIYSRLGINFEYDKENVYVRDKQELKVKLDFGGHIPKIDDGPWPAFPTDLMSIIIVT
ATQVEGTVLVFEKMFESRMFFVDKLIKMGAQIVLCDPHRVVVTGKSPLKGNVLSSPDVRAGMSLLIAAFVAEGRSEIQNV
YQIERGYEDVANKLINLGAKIKKVKSQ

Sequences:

>Translated_427_residues
MYSYIVEGGFKIGGQITASGNKNSALPCILAALLTNEDVILENIPNINDVKVVLDILSDIGADIVREGNALKIKVSNIVK
TEIDSSFTDLIRASILLLGPFVSRFGEIDMALPGGDVIGKRRLDTHFYGLSKLGAKLINKDGRIVLKAKKLVGAEMFLDE
ASVTATENIIMASVLAEGNTVIMNAACEPHVQDLCNMLNSMGANILGIGSNVLEIKGVKKLRGTTFRIGADFMQVGSLIS
LAALTGGELEIKKADPQHFRLIRHIYSRLGINFEYDKENVYVRDKQELKVKLDFGGHIPKIDDGPWPAFPTDLMSIIIVT
ATQVEGTVLVFEKMFESRMFFVDKLIKMGAQIVLCDPHRVVVTGKSPLKGNVLSSPDVRAGMSLLIAAFVAEGRSEIQNV
YQIERGYEDVANKLINLGAKIKKVKSQ
>Mature_427_residues
MYSYIVEGGFKIGGQITASGNKNSALPCILAALLTNEDVILENIPNINDVKVVLDILSDIGADIVREGNALKIKVSNIVK
TEIDSSFTDLIRASILLLGPFVSRFGEIDMALPGGDVIGKRRLDTHFYGLSKLGAKLINKDGRIVLKAKKLVGAEMFLDE
ASVTATENIIMASVLAEGNTVIMNAACEPHVQDLCNMLNSMGANILGIGSNVLEIKGVKKLRGTTFRIGADFMQVGSLIS
LAALTGGELEIKKADPQHFRLIRHIYSRLGINFEYDKENVYVRDKQELKVKLDFGGHIPKIDDGPWPAFPTDLMSIIIVT
ATQVEGTVLVFEKMFESRMFFVDKLIKMGAQIVLCDPHRVVVTGKSPLKGNVLSSPDVRAGMSLLIAAFVAEGRSEIQNV
YQIERGYEDVANKLINLGAKIKKVKSQ

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=432, Percent_Identity=35.1851851851852, Blast_Score=255, Evalue=5e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 46547; Mature: 46547

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYSYIVEGGFKIGGQITASGNKNSALPCILAALLTNEDVILENIPNINDVKVVLDILSDI
CCEEEEECCEEECCEEEECCCCCCCHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHH
GADIVREGNALKIKVSNIVKTEIDSSFTDLIRASILLLGPFVSRFGEIDMALPGGDVIGK
CHHHHCCCCEEEEEEHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCC
RRLDTHFYGLSKLGAKLINKDGRIVLKAKKLVGAEMFLDEASVTATENIIMASVLAEGNT
CHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCE
VIMNAACEPHVQDLCNMLNSMGANILGIGSNVLEIKGVKKLRGTTFRIGADFMQVGSLIS
EEEECCCCHHHHHHHHHHHHCCCCEEECCCCEEEECCCHHHCCCEEEECHHHHHHHHHHH
LAALTGGELEIKKADPQHFRLIRHIYSRLGINFEYDKENVYVRDKQELKVKLDFGGHIPK
HHHCCCCCEEEECCCHHHHHHHHHHHHHHCCCEEECCCCEEEECCCEEEEEEECCCCCCC
IDDGPWPAFPTDLMSIIIVTATQVEGTVLVFEKMFESRMFFVDKLIKMGAQIVLCDPHRV
CCCCCCCCCHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEE
VVTGKSPLKGNVLSSPDVRAGMSLLIAAFVAEGRSEIQNVYQIERGYEDVANKLINLGAK
EEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHH
IKKVKSQ
HHHHCCC
>Mature Secondary Structure
MYSYIVEGGFKIGGQITASGNKNSALPCILAALLTNEDVILENIPNINDVKVVLDILSDI
CCEEEEECCEEECCEEEECCCCCCCHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHH
GADIVREGNALKIKVSNIVKTEIDSSFTDLIRASILLLGPFVSRFGEIDMALPGGDVIGK
CHHHHCCCCEEEEEEHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCC
RRLDTHFYGLSKLGAKLINKDGRIVLKAKKLVGAEMFLDEASVTATENIIMASVLAEGNT
CHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCE
VIMNAACEPHVQDLCNMLNSMGANILGIGSNVLEIKGVKKLRGTTFRIGADFMQVGSLIS
EEEECCCCHHHHHHHHHHHHCCCCEEECCCCEEEECCCHHHCCCEEEECHHHHHHHHHHH
LAALTGGELEIKKADPQHFRLIRHIYSRLGINFEYDKENVYVRDKQELKVKLDFGGHIPK
HHHCCCCCEEEECCCHHHHHHHHHHHHHHCCCEEECCCCEEEECCCEEEEEEECCCCCCC
IDDGPWPAFPTDLMSIIIVTATQVEGTVLVFEKMFESRMFFVDKLIKMGAQIVLCDPHRV
CCCCCCCCCHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEE
VVTGKSPLKGNVLSSPDVRAGMSLLIAAFVAEGRSEIQNVYQIERGYEDVANKLINLGAK
EEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHH
IKKVKSQ
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9403685 [H]