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The map label for this gene is creB

Identifier: 51597482

GI number: 51597482

Start: 3729592

End: 3730290

Strand: Reverse

Name: creB

Synonym: YPTB3171

Alternate gene names: 51597482

Gene position: 3730290-3729592 (Counterclockwise)

Preceding gene: 51597483

Following gene: 51597481

Centisome position: 78.62

GC content: 49.64

Gene sequence:

>699_bases
ATGAAGCCACTGATCTGGTTGGTAGAAGATGAACCGAGTATCGCTGATACGTTGATTTATACGTTGGAAAGCGAAGGGTT
TACCCTCCGGTGGTTTGATCGGGGGGAGCCTGCCCTTGCCGCACTTAGCAGCGGTTCTCCCGCTTTGGCGATAGTGGATG
TTGGTTTGCCTGATATTAATGGCTTTGATCTGTGTCGCCGGATGCTGGCGGCAGCCCCCGATCTGCCCGTGATCTTCCTG
ACAGCCCGTAGCGAAGAGTTGGACCGAATTGTGGGGCTGGAAATTGGTGCTGACGATTATATTGCCAAACCGTTCTCCCC
CCGTGAGGTAAGTGCCCGAGTCCGTACCATATTGCGAAGATTACAAAAATCACACTTATTGGCGGTTACCTCCACATCAT
ATCAATTCGGTCATTTTTCGCTGGATGAAGCCGGTGCCAGAGTGACCTATCATCAACAGATTTTAGGGTTAACCCGCTAT
GAATATCTGCTGTTGAAAACCTTGTTACTGGCACCTGAACGCATATTTTCACGTCAACAATTAATGGATATTGTCTGGGC
GCAGGCGGAAGAAAGCCAAGATCGCACGGTCGATACTCACATCAAAACGCTACGATCAAAATTACGCACGGTTTACGCTG
AAGACTCACCCATTCGCACACATCGTGGATTGGGCTATAGCCTGGGTTATCAGCCATGA

Upstream 100 bases:

>100_bases
AGCGTCTATGGCTGTCCGCTGACAGCATGTCTGAAGATGAGTGGCGGCAGCTATGCCTGTTGCTGCGGCATTCATTTGAA
TCTGACGATGGAACGATGTG

Downstream 100 bases:

>100_bases
GCCGCTATAAATGAAGATTGGTGTACGGTTGCTACTTGGCTATTTCCTGATTGTGGCTATCGCTGGCTACTTTGTTATTC
GTATTTTTTTGCAGGAAGTC

Product: DNA-binding response regulator CreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MKPLIWLVEDEPSIADTLIYTLESEGFTLRWFDRGEPALAALSSGSPALAIVDVGLPDINGFDLCRRMLAAAPDLPVIFL
TARSEELDRIVGLEIGADDYIAKPFSPREVSARVRTILRRLQKSHLLAVTSTSYQFGHFSLDEAGARVTYHQQILGLTRY
EYLLLKTLLLAPERIFSRQQLMDIVWAQAEESQDRTVDTHIKTLRSKLRTVYAEDSPIRTHRGLGYSLGYQP

Sequences:

>Translated_232_residues
MKPLIWLVEDEPSIADTLIYTLESEGFTLRWFDRGEPALAALSSGSPALAIVDVGLPDINGFDLCRRMLAAAPDLPVIFL
TARSEELDRIVGLEIGADDYIAKPFSPREVSARVRTILRRLQKSHLLAVTSTSYQFGHFSLDEAGARVTYHQQILGLTRY
EYLLLKTLLLAPERIFSRQQLMDIVWAQAEESQDRTVDTHIKTLRSKLRTVYAEDSPIRTHRGLGYSLGYQP
>Mature_232_residues
MKPLIWLVEDEPSIADTLIYTLESEGFTLRWFDRGEPALAALSSGSPALAIVDVGLPDINGFDLCRRMLAAAPDLPVIFL
TARSEELDRIVGLEIGADDYIAKPFSPREVSARVRTILRRLQKSHLLAVTSTSYQFGHFSLDEAGARVTYHQQILGLTRY
EYLLLKTLLLAPERIFSRQQLMDIVWAQAEESQDRTVDTHIKTLRSKLRTVYAEDSPIRTHRGLGYSLGYQP

Specific function: Member of the two-component regulatory system CreC/CreB involved in catabolic regulation [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790860, Length=224, Percent_Identity=60.7142857142857, Blast_Score=280, Evalue=5e-77,
Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=40.625, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1786599, Length=224, Percent_Identity=37.9464285714286, Blast_Score=140, Evalue=7e-35,
Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=36, Blast_Score=133, Evalue=8e-33,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=34.2105263157895, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=33.0396475770925, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=33.0357142857143, Blast_Score=113, Evalue=9e-27,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=33.3333333333333, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=34.6491228070175, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1787375, Length=222, Percent_Identity=30.6306306306306, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI2367329, Length=225, Percent_Identity=37.3333333333333, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=31.5315315315315, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=32.5892857142857, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=26.8398268398268, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790299, Length=124, Percent_Identity=31.4516129032258, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788550, Length=139, Percent_Identity=28.7769784172662, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26175; Mature: 26175

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPLIWLVEDEPSIADTLIYTLESEGFTLRWFDRGEPALAALSSGSPALAIVDVGLPDIN
CCCEEEEEECCCCHHHHEEEEEECCCCEEEEECCCCCCEEEECCCCCEEEEEECCCCCCC
GFDLCRRMLAAAPDLPVIFLTARSEELDRIVGLEIGADDYIAKPFSPREVSARVRTILRR
HHHHHHHHHHCCCCCCEEEEEECCHHHHHHHCEEECCCCHHCCCCCCHHHHHHHHHHHHH
LQKSHLLAVTSTSYQFGHFSLDEAGARVTYHQQILGLTRYEYLLLKTLLLAPERIFSRQQ
HHHHHEEEEEECCEECCCEEHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
LMDIVWAQAEESQDRTVDTHIKTLRSKLRTVYAEDSPIRTHRGLGYSLGYQP
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCC
>Mature Secondary Structure
MKPLIWLVEDEPSIADTLIYTLESEGFTLRWFDRGEPALAALSSGSPALAIVDVGLPDIN
CCCEEEEEECCCCHHHHEEEEEECCCCEEEEECCCCCCEEEECCCCCEEEEEECCCCCCC
GFDLCRRMLAAAPDLPVIFLTARSEELDRIVGLEIGADDYIAKPFSPREVSARVRTILRR
HHHHHHHHHHCCCCCCEEEEEECCHHHHHHHCEEECCCCHHCCCCCCHHHHHHHHHHHHH
LQKSHLLAVTSTSYQFGHFSLDEAGARVTYHQQILGLTRYEYLLLKTLLLAPERIFSRQQ
HHHHHEEEEEECCEECCCEEHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
LMDIVWAQAEESQDRTVDTHIKTLRSKLRTVYAEDSPIRTHRGLGYSLGYQP
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3531171; 7610040; 9278503 [H]