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The map label for this gene is ydeV

Identifier: 51594905

GI number: 51594905

Start: 653923

End: 655515

Strand: Direct

Name: ydeV

Synonym: YPTB0554

Alternate gene names: 51594905

Gene position: 653923-655515 (Clockwise)

Preceding gene: 51594904

Following gene: 51594906

Centisome position: 13.78

GC content: 54.36

Gene sequence:

>1593_bases
ATGAGTCAACTCGATACGACTACCCCATCAGGTGATTACTTGATGGCGCTGGATGCCGGTACCGGCAGTGTCCGGGCGGT
GATATTTGATCTTAATGGTAATCAGATTGCCGCCGGGCAGGCGGAGTGGCTGCATCTGCCGGTACCCGATGTTCCGGGGT
CGATGGAGTTTGATTTAACCACCAATTGGCAACTCACGTGCCAGTGTATCCGCCAGGCACTGCATTTGGCTAAGTTACCG
GCCAGTGCTATCCGTGCTGTCGCTGCCTGTTCAATGCGTGAAGGGATCGTACTCTATGATCGCAGTGGAACCCCGATCTG
GGCCTGTGCCAATGTGGATGCTCGCGCCAGCCGTGAAGTCAGCGAATTAAAAGAGCTGCACAATAATGGATTTGAGTTAG
AAGTCTATCAATGCTCCGGCCAGACGCTGGCACTGAGTGCCATGCCCCGGTTGTTGTGGTTGGCGCACTATCGGCCCGAT
ATTTATCGTCAGGCAGGAACACTGACCATGATCAGTGACTGGCTGGCCAATATGCTCAGTGGGGAGCTGGCGGTCGATCC
CTCCAACGCGGGGACCACGGGTATGCTGGATCTCGTCACCCGTAACTGGCAACCGAACTTGCTGGAAATGGCCGGGTTAC
GTGCGGATATTCTCTCGCCAGTGAAAGAGACAGGCACCTTGTTGGGCCATGTCACGGCGAAGGCCGCGCAAGAATGTGGT
TTGCTGGCCGGAACGCCGGTGGTGATGGGCGGTGGCGATGTACAACTGGGTTGTTTGGGGTTGGGAGTGGTGCACGCAGG
TCAGACGGCGGTATTGGGCGGTACTTTCTGGCAGCAGGTGGTTAATTTACCGCAGCCGATTATTGATCCCAATATGAATA
CCCGAATAAACCCTCATGTTATCCCCGGTATGGTTCAGGCGGAGTCCATCAGCTTCTTTACTGGTCTGACAATGCGCTGG
TTCCGTGATGCGTTTTGCGCCGAAGAAAAATTACTGGCGCAGCGATTGGGGATTGATACCTACAGTTTATTGGAGGATAT
GGCCGCCAGGGTCCCCGCCGGTGCTTATGGGGTCATGCCTATCTTCTCTGATGTGATGCGTTTTAAATCTTGGTATCACG
CCGCGCCTTCATTTATTAACCTCTCACTCGATCCTGAAAAATGTAATAAAGCCACGTTATTCCGTGCGTTGGAAGAGAAT
GCGGCCATCGTCTCGGCCTGTAATTTAGCGCAAATTGCTGAATTCTCTGGCGTGAAAGCCTCGTCGGTGGTTTTTGCTGG
CGGTGGCGCGAAAGGCAAACTGTGGAGCCAGATTCTGGCTGATGTCACCGGTGTTCCGGTGAAGGTGCCGGTGGTCAAAG
AAGCAACCGCATTAGGCTGCGCGATTGCCGCCGGTGTTGGTGTCGGCCTATATGAAGCATTGGATAAAACCGGCGAGCGG
CTCGTGCGCTGGGAGCGGGAATACATCCCGAATACTGAGCATAAAGCGCTCTATCAAGCGGCAAAAACTAACTGGCAAGC
GGTGTATACCGATCAACTGGGGCTGGTGGATTGTGGGTTGACGACGTCTCTTTGGAAGGCTCCTGGCCTCTAA

Upstream 100 bases:

>100_bases
AGGCTCCGATCTCTGCGCGCGGTCCCACAGGCAACTTGAAATATGACGGGTAAACACTGCGGTGACGCCAAATAAGCAGG
GTATTCAAGAGGAGCGCGCA

Downstream 100 bases:

>100_bases
AATGGATTATCTTCATTAATTGACTATCTTCATTCATTAACTATTTTGATTAATTAACTAGCTTGATTAATTAATAGCGA
AAAGCGGCCAGCTTGCGCTT

Product: autoinducer-2 (AI-2) kinase

Products: NA

Alternate protein names: AI-2 kinase

Number of amino acids: Translated: 530; Mature: 529

Protein sequence:

>530_residues
MSQLDTTTPSGDYLMALDAGTGSVRAVIFDLNGNQIAAGQAEWLHLPVPDVPGSMEFDLTTNWQLTCQCIRQALHLAKLP
ASAIRAVAACSMREGIVLYDRSGTPIWACANVDARASREVSELKELHNNGFELEVYQCSGQTLALSAMPRLLWLAHYRPD
IYRQAGTLTMISDWLANMLSGELAVDPSNAGTTGMLDLVTRNWQPNLLEMAGLRADILSPVKETGTLLGHVTAKAAQECG
LLAGTPVVMGGGDVQLGCLGLGVVHAGQTAVLGGTFWQQVVNLPQPIIDPNMNTRINPHVIPGMVQAESISFFTGLTMRW
FRDAFCAEEKLLAQRLGIDTYSLLEDMAARVPAGAYGVMPIFSDVMRFKSWYHAAPSFINLSLDPEKCNKATLFRALEEN
AAIVSACNLAQIAEFSGVKASSVVFAGGGAKGKLWSQILADVTGVPVKVPVVKEATALGCAIAAGVGVGLYEALDKTGER
LVRWEREYIPNTEHKALYQAAKTNWQAVYTDQLGLVDCGLTTSLWKAPGL

Sequences:

>Translated_530_residues
MSQLDTTTPSGDYLMALDAGTGSVRAVIFDLNGNQIAAGQAEWLHLPVPDVPGSMEFDLTTNWQLTCQCIRQALHLAKLP
ASAIRAVAACSMREGIVLYDRSGTPIWACANVDARASREVSELKELHNNGFELEVYQCSGQTLALSAMPRLLWLAHYRPD
IYRQAGTLTMISDWLANMLSGELAVDPSNAGTTGMLDLVTRNWQPNLLEMAGLRADILSPVKETGTLLGHVTAKAAQECG
LLAGTPVVMGGGDVQLGCLGLGVVHAGQTAVLGGTFWQQVVNLPQPIIDPNMNTRINPHVIPGMVQAESISFFTGLTMRW
FRDAFCAEEKLLAQRLGIDTYSLLEDMAARVPAGAYGVMPIFSDVMRFKSWYHAAPSFINLSLDPEKCNKATLFRALEEN
AAIVSACNLAQIAEFSGVKASSVVFAGGGAKGKLWSQILADVTGVPVKVPVVKEATALGCAIAAGVGVGLYEALDKTGER
LVRWEREYIPNTEHKALYQAAKTNWQAVYTDQLGLVDCGLTTSLWKAPGL
>Mature_529_residues
SQLDTTTPSGDYLMALDAGTGSVRAVIFDLNGNQIAAGQAEWLHLPVPDVPGSMEFDLTTNWQLTCQCIRQALHLAKLPA
SAIRAVAACSMREGIVLYDRSGTPIWACANVDARASREVSELKELHNNGFELEVYQCSGQTLALSAMPRLLWLAHYRPDI
YRQAGTLTMISDWLANMLSGELAVDPSNAGTTGMLDLVTRNWQPNLLEMAGLRADILSPVKETGTLLGHVTAKAAQECGL
LAGTPVVMGGGDVQLGCLGLGVVHAGQTAVLGGTFWQQVVNLPQPIIDPNMNTRINPHVIPGMVQAESISFFTGLTMRWF
RDAFCAEEKLLAQRLGIDTYSLLEDMAARVPAGAYGVMPIFSDVMRFKSWYHAAPSFINLSLDPEKCNKATLFRALEENA
AIVSACNLAQIAEFSGVKASSVVFAGGGAKGKLWSQILADVTGVPVKVPVVKEATALGCAIAAGVGVGLYEALDKTGERL
VRWEREYIPNTEHKALYQAAKTNWQAVYTDQLGLVDCGLTTSLWKAPGL

Specific function: Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family

Homologues:

Organism=Homo sapiens, GI42794763, Length=477, Percent_Identity=24.5283018867925, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1787789, Length=530, Percent_Identity=78.4905660377359, Blast_Score=872, Evalue=0.0,
Organism=Escherichia coli, GI1790005, Length=501, Percent_Identity=25.1497005988024, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1790361, Length=496, Percent_Identity=25.8064516129032, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1789168, Length=498, Percent_Identity=23.8955823293173, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1789138, Length=525, Percent_Identity=23.4285714285714, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1789987, Length=522, Percent_Identity=24.5210727969349, Blast_Score=87, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17535599, Length=462, Percent_Identity=25.5411255411255, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LSRK_YERP3 (A7FMJ5)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001402473.1
- ProteinModelPortal:   A7FMJ5
- STRING:   A7FMJ5
- GeneID:   5387201
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_3518
- eggNOG:   COG1070
- HOGENOM:   HBG337781
- OMA:   PIFSDAM
- ProtClustDB:   PRK10939
- BioCyc:   YPSE349747:YPSIP31758_3518-MONOMER
- GO:   GO:0005737
- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018484
- PANTHER:   PTHR10196

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N

EC number: NA

Molecular weight: Translated: 56995; Mature: 56864

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: PS00933 FGGY_KINASES_1; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQLDTTTPSGDYLMALDAGTGSVRAVIFDLNGNQIAAGQAEWLHLPVPDVPGSMEFDLT
CCCCCCCCCCCCEEEEEECCCCCEEEEEEECCCCEEECCCCCEEEECCCCCCCCEEEEEE
TNWQLTCQCIRQALHLAKLPASAIRAVAACSMREGIVLYDRSGTPIWACANVDARASREV
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEECCCCCEEEECCCCCHHHHHH
SELKELHNNGFELEVYQCSGQTLALSAMPRLLWLAHYRPDIYRQAGTLTMISDWLANMLS
HHHHHHHCCCCEEEEEEECCCEEEHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHC
GELAVDPSNAGTTGMLDLVTRNWQPNLLEMAGLRADILSPVKETGTLLGHVTAKAAQECG
CCEEECCCCCCCCCHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
LLAGTPVVMGGGDVQLGCLGLGVVHAGQTAVLGGTFWQQVVNLPQPIIDPNMNTRINPHV
CEECCCEEECCCCEEEEEEEEEEEECCCEEEECHHHHHHHHCCCCCCCCCCCCCCCCCCC
IPGMVQAESISFFTGLTMRWFRDAFCAEEKLLAQRLGIDTYSLLEDMAARVPAGAYGVMP
CCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHH
IFSDVMRFKSWYHAAPSFINLSLDPEKCNKATLFRALEENAAIVSACNLAQIAEFSGVKA
HHHHHHHHHHHHHCCCCEEEEEECHHHCCHHHHHHHHHCCCCEEECCCHHHHHHHCCCCC
SSVVFAGGGAKGKLWSQILADVTGVPVKVPVVKEATALGCAIAAGVGVGLYEALDKTGER
CEEEEECCCCCHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LVRWEREYIPNTEHKALYQAAKTNWQAVYTDQLGLVDCGLTTSLWKAPGL
HHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCEEECCCCHHHHCCCCC
>Mature Secondary Structure 
SQLDTTTPSGDYLMALDAGTGSVRAVIFDLNGNQIAAGQAEWLHLPVPDVPGSMEFDLT
CCCCCCCCCCCEEEEEECCCCCEEEEEEECCCCEEECCCCCEEEECCCCCCCCEEEEEE
TNWQLTCQCIRQALHLAKLPASAIRAVAACSMREGIVLYDRSGTPIWACANVDARASREV
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEECCCCCEEEECCCCCHHHHHH
SELKELHNNGFELEVYQCSGQTLALSAMPRLLWLAHYRPDIYRQAGTLTMISDWLANMLS
HHHHHHHCCCCEEEEEEECCCEEEHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHC
GELAVDPSNAGTTGMLDLVTRNWQPNLLEMAGLRADILSPVKETGTLLGHVTAKAAQECG
CCEEECCCCCCCCCHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
LLAGTPVVMGGGDVQLGCLGLGVVHAGQTAVLGGTFWQQVVNLPQPIIDPNMNTRINPHV
CEECCCEEECCCCEEEEEEEEEEEECCCEEEECHHHHHHHHCCCCCCCCCCCCCCCCCCC
IPGMVQAESISFFTGLTMRWFRDAFCAEEKLLAQRLGIDTYSLLEDMAARVPAGAYGVMP
CCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHH
IFSDVMRFKSWYHAAPSFINLSLDPEKCNKATLFRALEENAAIVSACNLAQIAEFSGVKA
HHHHHHHHHHHHHCCCCEEEEEECHHHCCHHHHHHHHHCCCCEEECCCHHHHHHHCCCCC
SSVVFAGGGAKGKLWSQILADVTGVPVKVPVVKEATALGCAIAAGVGVGLYEALDKTGER
CEEEEECCCCCHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LVRWEREYIPNTEHKALYQAAKTNWQAVYTDQLGLVDCGLTTSLWKAPGL
HHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCEEECCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA