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The map label for this gene is ltrA [H]

Identifier: 51594688

GI number: 51594688

Start: 397635

End: 398621

Strand: Reverse

Name: ltrA [H]

Synonym: YPTB0333

Alternate gene names: 51594688

Gene position: 398621-397635 (Counterclockwise)

Preceding gene: 51594691

Following gene: 51594666

Centisome position: 8.4

GC content: 38.4

Gene sequence:

>987_bases
ATGATGTCAATAGATGAAAACACTTTTGCATTTAGCGCAAAAATAAATAATCATGCCATTTATAAGCATTTAGAGAATTT
TATCAAAATTGTTGAATGCAACAGCCTATCCATTGCTGCACATAAATTAAATATAACACCGTCTTCCACTAGCCGTAGTC
TGGCTCAATTAGAGGAGAAGCTCGGTGTGGTACTATTAAAAAGAACCACTCGCAGCATCGTTTTAACCGATGCTGGCGAT
TACTTGTTTCATCAGGCGCGCCAACTCCTTTTGGATCTGGATGAAACACTGGTTAATACGCATAGTTTTTATAACCACCC
ACAGGGGCAGCTCAAGATTACCTGCTCTATCGCTTTTGGTGTCTGTCATTTAATGCATCTATTTAGTCAATATAAAGAAA
CTAACAGCGATGTCTGTTTATCGGTAGATTTAAATGATCAGTTAGTGAATTTAAATGAAGAACATTTTGATATTGCCTTG
CGTATCACCTCAATTCCCCCGCCTAATTTTGCTATACGAAGGATTTGTACCATTAACTGGGTTTATTGTGGCAGTAAAGA
ATATCTAATGAAACGCGGTGTTCCAGCCACTATCGAAGATCTTGAGCAACATGATTGCCTGGTAAACCCTAACGTTTCCG
ATGCCTGGTTATATAAAAGTACAGAGGGTGAGAGCGTCCCCTTGAAAATAAAAAATACCGTGCAGGCCAACAGCAGCCTG
GGGTTATTACATGCTGCGCTGCATCATCAGGGCATTGTCTGTCTACCTACTTATATGCTGGGCGACTATATAACCTCAGG
TAAATTAGTGCCTATTTTACTGGATTATAATGCTAAAGATAAAGAATATGGCCTATATGCTTTATATTACCCTAGCAAAT
ATAACGATCCAAAAATAAGAAGTTTTATTGATTTTATGTTGGATGAACTGTCAATGGACGTGCCATGGGATAAATGGAGA
GCAGATTATCAAATCTCATTATCCTGA

Upstream 100 bases:

>100_bases
GAAAAATAAAACCGTTTGACTATCTACAAAAAAGCAATATTTCATTTTAAAAACTAACAGGTGTAGTATTGTCTAAATAA
ACTATTAATAATATAGGTGT

Downstream 100 bases:

>100_bases
CGATGACAGACACTCACCCTGCAAGCAGTTGGAAGGAGCCTGTGTCCGCGCCAGACAAAGCGCGGCCCCGGATAATATCA
GCGCTGAATCAAATAGCGAA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MMSIDENTFAFSAKINNHAIYKHLENFIKIVECNSLSIAAHKLNITPSSTSRSLAQLEEKLGVVLLKRTTRSIVLTDAGD
YLFHQARQLLLDLDETLVNTHSFYNHPQGQLKITCSIAFGVCHLMHLFSQYKETNSDVCLSVDLNDQLVNLNEEHFDIAL
RITSIPPPNFAIRRICTINWVYCGSKEYLMKRGVPATIEDLEQHDCLVNPNVSDAWLYKSTEGESVPLKIKNTVQANSSL
GLLHAALHHQGIVCLPTYMLGDYITSGKLVPILLDYNAKDKEYGLYALYYPSKYNDPKIRSFIDFMLDELSMDVPWDKWR
ADYQISLS

Sequences:

>Translated_328_residues
MMSIDENTFAFSAKINNHAIYKHLENFIKIVECNSLSIAAHKLNITPSSTSRSLAQLEEKLGVVLLKRTTRSIVLTDAGD
YLFHQARQLLLDLDETLVNTHSFYNHPQGQLKITCSIAFGVCHLMHLFSQYKETNSDVCLSVDLNDQLVNLNEEHFDIAL
RITSIPPPNFAIRRICTINWVYCGSKEYLMKRGVPATIEDLEQHDCLVNPNVSDAWLYKSTEGESVPLKIKNTVQANSSL
GLLHAALHHQGIVCLPTYMLGDYITSGKLVPILLDYNAKDKEYGLYALYYPSKYNDPKIRSFIDFMLDELSMDVPWDKWR
ADYQISLS
>Mature_328_residues
MMSIDENTFAFSAKINNHAIYKHLENFIKIVECNSLSIAAHKLNITPSSTSRSLAQLEEKLGVVLLKRTTRSIVLTDAGD
YLFHQARQLLLDLDETLVNTHSFYNHPQGQLKITCSIAFGVCHLMHLFSQYKETNSDVCLSVDLNDQLVNLNEEHFDIAL
RITSIPPPNFAIRRICTINWVYCGSKEYLMKRGVPATIEDLEQHDCLVNPNVSDAWLYKSTEGESVPLKIKNTVQANSSL
GLLHAALHHQGIVCLPTYMLGDYITSGKLVPILLDYNAKDKEYGLYALYYPSKYNDPKIRSFIDFMLDELSMDVPWDKWR
ADYQISLS

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=291, Percent_Identity=30.9278350515464, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1789440, Length=297, Percent_Identity=26.9360269360269, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI87081978, Length=297, Percent_Identity=27.9461279461279, Blast_Score=121, Evalue=7e-29,
Organism=Escherichia coli, GI1789639, Length=290, Percent_Identity=26.8965517241379, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1787589, Length=276, Percent_Identity=25.7246376811594, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1787128, Length=286, Percent_Identity=24.8251748251748, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI145693193, Length=274, Percent_Identity=26.2773722627737, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI145693105, Length=92, Percent_Identity=36.9565217391304, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1788706, Length=283, Percent_Identity=21.5547703180212, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 37311; Mature: 37311

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSIDENTFAFSAKINNHAIYKHLENFIKIVECNSLSIAAHKLNITPSSTSRSLAQLEEK
CCCCCCCCEEEEEEECCHHHHHHHHHHHEEEECCCEEEEEEEEECCCCCCHHHHHHHHHH
LGVVLLKRTTRSIVLTDAGDYLFHQARQLLLDLDETLVNTHSFYNHPQGQLKITCSIAFG
HCEEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHH
VCHLMHLFSQYKETNSDVCLSVDLNDQLVNLNEEHFDIALRITSIPPPNFAIRRICTINW
HHHHHHHHHHHHCCCCCEEEEEECCCCEECCCCCCEEEEEEEECCCCCCHHEEEEEEEEE
VYCGSKEYLMKRGVPATIEDLEQHDCLVNPNVSDAWLYKSTEGESVPLKIKNTVQANSSL
EEECCHHHHHHCCCCHHHHHHHHCCCEECCCCCCEEEEECCCCCCCCEEEECEEECCCCH
GLLHAALHHQGIVCLPTYMLGDYITSGKLVPILLDYNAKDKEYGLYALYYPSKYNDPKIR
HHHHHHHHHCCEEEEHHHHHHHHHCCCCEEEEEEECCCCCCCCCEEEEECCCCCCCHHHH
SFIDFMLDELSMDVPWDKWRADYQISLS
HHHHHHHHHHCCCCCHHHHCCCEEEEEC
>Mature Secondary Structure
MMSIDENTFAFSAKINNHAIYKHLENFIKIVECNSLSIAAHKLNITPSSTSRSLAQLEEK
CCCCCCCCEEEEEEECCHHHHHHHHHHHEEEECCCEEEEEEEEECCCCCCHHHHHHHHHH
LGVVLLKRTTRSIVLTDAGDYLFHQARQLLLDLDETLVNTHSFYNHPQGQLKITCSIAFG
HCEEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHH
VCHLMHLFSQYKETNSDVCLSVDLNDQLVNLNEEHFDIALRITSIPPPNFAIRRICTINW
HHHHHHHHHHHHCCCCCEEEEEECCCCEECCCCCCEEEEEEEECCCCCCHHEEEEEEEEE
VYCGSKEYLMKRGVPATIEDLEQHDCLVNPNVSDAWLYKSTEGESVPLKIKNTVQANSSL
EEECCHHHHHHCCCCHHHHHHHHCCCEECCCCCCEEEEECCCCCCCCEEEECEEECCCCH
GLLHAALHHQGIVCLPTYMLGDYITSGKLVPILLDYNAKDKEYGLYALYYPSKYNDPKIR
HHHHHHHHHCCEEEEHHHHHHHHHCCCCEEEEEEECCCCCCCCCEEEEECCCCCCCHHHH
SFIDFMLDELSMDVPWDKWRADYQISLS
HHHHHHHHHHCCCCCHHHHCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8748036 [H]