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The map label for this gene is rutG [H]

Identifier: 50842006

GI number: 50842006

Start: 575226

End: 576671

Strand: Reverse

Name: rutG [H]

Synonym: PPA0522

Alternate gene names: 50842006

Gene position: 576671-575226 (Counterclockwise)

Preceding gene: 50842007

Following gene: 50842005

Centisome position: 22.52

GC content: 59.61

Gene sequence:

>1446_bases
ATGATTTGGAAACTGCACAATCGCGGTGTACTAGAATCGGGTGAGGTGGTGGCTCCCGACGAGAGACTCGGGTGGGGCCG
CACCATTGGGCTAGGAGCCCAGCACGTGGTAGCCATGTTTGGGGCGACTTTCGTCTTCCCCGTTCTCATGGGTCTCAACC
CGCAGTTAGCGGTCATGATGTCGGGTGTGGCAACCCTGGTGTTTATCTTCGTCACTCAGCATGAAGTGCCGTCTTATCTC
GGCTCGTCGGCCGCGTTTCCTGGAGTAGCGACCGCGATCTACGCCTCGGGCGGTAAACCCAATGACGTCTCAGGCGCCCT
ACTGTGTGTCGGCCTGACCCTACTTATTTGCGGCATCATCATCCAGGCCGCCGGATCTCGGGTAGTCCATAAGGTTTTGC
CACCGACGGTGACCGGCGCGGTCGTTATGCTCATCGGGTTCAACCTCGCCCCGGTCGTCGCCAAAACGTACTGGCCTACC
GATCAGTGGACGGCGCTCATCGTCATGTTGCTCGTCATTGCGTTGTCGGTAGGACCGCGTGGCTTCGTGTCCCGGATCGC
TATCTTCCTGGCTCTGGTTATCGGCTATCTGCTGTCGTGGACCGAAGATCTCGTATTTGGCCCGCTGCACCACTCCGATG
GCAGCACCGCCCCGCGAGTGGACTGGTCGGCGGTACACAACTCCGCGTGGATCGGCCTACCTCCGGCGACGAACCTAAAC
AACTGGCAATACCTGCCCCAGGTTCACAACGGATCCCACTACGCATCAACCAATGTCGTCGGATTTCACCTGCCGGCCTT
CCACTTGGCCTTCATCTTGCTAGCTTTGCCGGTGGTTATCGCCCTCATCGCTGAGAACACCGGCCACGTCAAAGCGGTCG
CTGAAATGACCGGTAAGAACCTTGACCACCAGGTCGGACGGGCGGTGGCTGCCGATGGTGCGACCTCAATGCTGGCGACC
TTCCTGGGTGCCGGCCCGACGACCACCTACTCGGAGAACATCGGCGTCATGGCCGCCACGAGGGTGTACTCGACGGCTGC
CTATGTGGTAGCCGCAGTCGTGGCGATCCTGTTCGGTTTCTCCCCTAAGTTTGGCGCCGTTATCTCGGCGACCCCCGGCG
GAGTCCTGGGTGGCATCACCGTGGTCCTCTACGGGATGATCGGTCTGCTCGGGGCGAAGATTTGGAAGGAGAATGAAGTC
GATTTCGGCAACCCGGTGAACCTCGTCCCGGTGGCCGCTGGGATCATCATCGGTGTCGGCGATGTGTCACTGAAATTCAG
CAAGTCCTTCACTTTGGGTGGCATCGCTCTAGGCACCATCGTCACCGTCGGTGTCTATCATCTAGCTAGGTGGCTAGCCC
CACATGAACTATCTGACGCGGCGGGTGGCACCAACATCATTCTTGACGCCCCAGGAATGTATGTCGATGACGACACCCCC
CAGTAA

Upstream 100 bases:

>100_bases
TTCCACTCCTGGATCTAAGCTCCGTCGGGGCCTGGGCGGACGTGCCCGCCCGACCGATACGCTGAGACTCCGGAAGGGAG
CCAACCCCGGAAGGACACGC

Downstream 100 bases:

>100_bases
TCGCGATCACGACGGGGGCGACCGATGCCATACGCAGTAGGCTTGCCGCGCAAGTGTTCGGAGGAGGCGATCAATGTCAG
GAACATTCCAGCCCAAAAAC

Product: putative uracyl permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MIWKLHNRGVLESGEVVAPDERLGWGRTIGLGAQHVVAMFGATFVFPVLMGLNPQLAVMMSGVATLVFIFVTQHEVPSYL
GSSAAFPGVATAIYASGGKPNDVSGALLCVGLTLLICGIIIQAAGSRVVHKVLPPTVTGAVVMLIGFNLAPVVAKTYWPT
DQWTALIVMLLVIALSVGPRGFVSRIAIFLALVIGYLLSWTEDLVFGPLHHSDGSTAPRVDWSAVHNSAWIGLPPATNLN
NWQYLPQVHNGSHYASTNVVGFHLPAFHLAFILLALPVVIALIAENTGHVKAVAEMTGKNLDHQVGRAVAADGATSMLAT
FLGAGPTTTYSENIGVMAATRVYSTAAYVVAAVVAILFGFSPKFGAVISATPGGVLGGITVVLYGMIGLLGAKIWKENEV
DFGNPVNLVPVAAGIIIGVGDVSLKFSKSFTLGGIALGTIVTVGVYHLARWLAPHELSDAAGGTNIILDAPGMYVDDDTP
Q

Sequences:

>Translated_481_residues
MIWKLHNRGVLESGEVVAPDERLGWGRTIGLGAQHVVAMFGATFVFPVLMGLNPQLAVMMSGVATLVFIFVTQHEVPSYL
GSSAAFPGVATAIYASGGKPNDVSGALLCVGLTLLICGIIIQAAGSRVVHKVLPPTVTGAVVMLIGFNLAPVVAKTYWPT
DQWTALIVMLLVIALSVGPRGFVSRIAIFLALVIGYLLSWTEDLVFGPLHHSDGSTAPRVDWSAVHNSAWIGLPPATNLN
NWQYLPQVHNGSHYASTNVVGFHLPAFHLAFILLALPVVIALIAENTGHVKAVAEMTGKNLDHQVGRAVAADGATSMLAT
FLGAGPTTTYSENIGVMAATRVYSTAAYVVAAVVAILFGFSPKFGAVISATPGGVLGGITVVLYGMIGLLGAKIWKENEV
DFGNPVNLVPVAAGIIIGVGDVSLKFSKSFTLGGIALGTIVTVGVYHLARWLAPHELSDAAGGTNIILDAPGMYVDDDTP
Q
>Mature_481_residues
MIWKLHNRGVLESGEVVAPDERLGWGRTIGLGAQHVVAMFGATFVFPVLMGLNPQLAVMMSGVATLVFIFVTQHEVPSYL
GSSAAFPGVATAIYASGGKPNDVSGALLCVGLTLLICGIIIQAAGSRVVHKVLPPTVTGAVVMLIGFNLAPVVAKTYWPT
DQWTALIVMLLVIALSVGPRGFVSRIAIFLALVIGYLLSWTEDLVFGPLHHSDGSTAPRVDWSAVHNSAWIGLPPATNLN
NWQYLPQVHNGSHYASTNVVGFHLPAFHLAFILLALPVVIALIAENTGHVKAVAEMTGKNLDHQVGRAVAADGATSMLAT
FLGAGPTTTYSENIGVMAATRVYSTAAYVVAAVVAILFGFSPKFGAVISATPGGVLGGITVVLYGMIGLLGAKIWKENEV
DFGNPVNLVPVAAGIIIGVGDVSLKFSKSFTLGGIALGTIVTVGVYHLARWLAPHELSDAAGGTNIILDAPGMYVDDDTP
Q

Specific function: May function as a proton-driven pyrimidine uptake system [H]

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081818, Length=444, Percent_Identity=42.7927927927928, Blast_Score=322, Evalue=3e-89,
Organism=Escherichia coli, GI1788843, Length=474, Percent_Identity=31.4345991561181, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI87082181, Length=432, Percent_Identity=25.462962962963, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI87082178, Length=272, Percent_Identity=25, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17542260, Length=173, Percent_Identity=32.3699421965318, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71993493, Length=166, Percent_Identity=32.5301204819277, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI21356175, Length=129, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019918
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 50227; Mature: 50227

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIWKLHNRGVLESGEVVAPDERLGWGRTIGLGAQHVVAMFGATFVFPVLMGLNPQLAVMM
CEEEECCCCCCCCCCEECCHHHCCCCCEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHH
SGVATLVFIFVTQHEVPSYLGSSAAFPGVATAIYASGGKPNDVSGALLCVGLTLLICGII
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHH
IQAAGSRVVHKVLPPTVTGAVVMLIGFNLAPVVAKTYWPTDQWTALIVMLLVIALSVGPR
HHHCCHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCH
GFVSRIAIFLALVIGYLLSWTEDLVFGPLHHSDGSTAPRVDWSAVHNSAWIGLPPATNLN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCCEEECCCCCCCC
NWQYLPQVHNGSHYASTNVVGFHLPAFHLAFILLALPVVIALIAENTGHVKAVAEMTGKN
CCEECCCCCCCCCEECCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCC
LDHQVGRAVAADGATSMLATFLGAGPTTTYSENIGVMAATRVYSTAAYVVAAVVAILFGF
CHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCC
SPKFGAVISATPGGVLGGITVVLYGMIGLLGAKIWKENEVDFGNPVNLVPVAAGIIIGVG
CCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCEEEECC
DVSLKFSKSFTLGGIALGTIVTVGVYHLARWLAPHELSDAAGGTNIILDAPGMYVDDDTP
CCEEEECCCCEECHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCEEEEECCCCCCCCCCC
Q
C
>Mature Secondary Structure
MIWKLHNRGVLESGEVVAPDERLGWGRTIGLGAQHVVAMFGATFVFPVLMGLNPQLAVMM
CEEEECCCCCCCCCCEECCHHHCCCCCEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHH
SGVATLVFIFVTQHEVPSYLGSSAAFPGVATAIYASGGKPNDVSGALLCVGLTLLICGII
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHH
IQAAGSRVVHKVLPPTVTGAVVMLIGFNLAPVVAKTYWPTDQWTALIVMLLVIALSVGPR
HHHCCHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCH
GFVSRIAIFLALVIGYLLSWTEDLVFGPLHHSDGSTAPRVDWSAVHNSAWIGLPPATNLN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCCEEECCCCCCCC
NWQYLPQVHNGSHYASTNVVGFHLPAFHLAFILLALPVVIALIAENTGHVKAVAEMTGKN
CCEECCCCCCCCCEECCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCC
LDHQVGRAVAADGATSMLATFLGAGPTTTYSENIGVMAATRVYSTAAYVVAAVVAILFGF
CHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCC
SPKFGAVISATPGGVLGGITVVLYGMIGLLGAKIWKENEVDFGNPVNLVPVAAGIIIGVG
CCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCEEEECC
DVSLKFSKSFTLGGIALGTIVTVGVYHLARWLAPHELSDAAGGTNIILDAPGMYVDDDTP
CCEEEECCCCEECHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCEEEEECCCCCCCCCCC
Q
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]