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The map label for this gene is iolE [H]

Identifier: 50841951

GI number: 50841951

Start: 517136

End: 517999

Strand: Reverse

Name: iolE [H]

Synonym: PPA0468

Alternate gene names: 50841951

Gene position: 517999-517136 (Counterclockwise)

Preceding gene: 50841955

Following gene: 50841943

Centisome position: 20.23

GC content: 59.95

Gene sequence:

>864_bases
ATGAAGATTGCCGGAGCGCCCATCAGCTGGGGCGTCTGCGAGGTCCCGAACTGGGGCTACCAGATGACGCCGGAGCGAGT
CCTCACCGAGATGAAGCAGATCGGCCTCACCGCCACCGAGTTTGGCCCCCAGGGCTGGTTACCTATTGAGGCAGAAGCCC
GCGCCACAGAAGTGAAAAAGTACGGTCTCAAGCCCGTGGGAGCGTTCTTCCTGTCCGTCATGCACGATCCGGACTTCGAT
CCGATCCCCATGGTGAACAAGGAGCTTGACGCCTTCGAAGCTGCCGGGGGTGACTATCTCATCCTCGCCACGGATTCCGG
ACGCGATGGATACGACGACCGCCCTGTCCTCGACGAGGCCGGCTGGAAAACGCTATTCACCAACCTGGACCAGATCCGCG
AAGTCTGCGCCAGCCGCAACGTCACCGCCTGTCTACACCCCCATTGGGGAACGATGGTCCAGAACCGTGACGAAGTGATC
CGCGTGCTCGAGAACTCCTCGATCGGGCTGTGCCTGGACACTGGCCATCTGGCCTGTGGTGGTACCGATGTCGTTGAGCT
GGTGCGTAAGTACGCCAACCGCGTCGACATTGTCCACGCCAAAGATGTCCATAAGGAGATGGCCGACAAGCTTTTGCCTG
GCGAGATCACCTGGTCCGAAGGCATTCGCGCCGGGATGTTCGCACCCATCGGCGACGGTGATATCGACTTTGCAGCCATC
GTGAGGCTCCTTGATGAAGCCGGGTTCGATGGTTATTACGTCCTAGAGCAGGACATCATGATCGACGAGGAACCACCCGC
CGACGACGGCCCGATTATCAACGCCAAGAAATCTTACGAGGCCCTGGCATCGCTGGGACGATGA

Upstream 100 bases:

>100_bases
GCCAGCGACAGCTATTGCCCCACTATTTGACAGGACATATACTACCGAGAGCGGCCTGATGCACAGGAGCTCAGGCCTCC
AAGACACGAGGAGCACATCG

Downstream 100 bases:

>100_bases
GCCCTGCACGCCGCTGAGCCAAGTTGGATCACGATGGTGGCCCGTCCTCCGCGGAGGACGGGCCACCATGCGGTTCCGTT
AATCTCCACACTGGCGGTTG

Product: putative myo-inositol catabolism protein

Products: NA

Alternate protein names: 2-keto-myo-inositol dehydratase; 2KMI dehydratase [H]

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MKIAGAPISWGVCEVPNWGYQMTPERVLTEMKQIGLTATEFGPQGWLPIEAEARATEVKKYGLKPVGAFFLSVMHDPDFD
PIPMVNKELDAFEAAGGDYLILATDSGRDGYDDRPVLDEAGWKTLFTNLDQIREVCASRNVTACLHPHWGTMVQNRDEVI
RVLENSSIGLCLDTGHLACGGTDVVELVRKYANRVDIVHAKDVHKEMADKLLPGEITWSEGIRAGMFAPIGDGDIDFAAI
VRLLDEAGFDGYYVLEQDIMIDEEPPADDGPIINAKKSYEALASLGR

Sequences:

>Translated_287_residues
MKIAGAPISWGVCEVPNWGYQMTPERVLTEMKQIGLTATEFGPQGWLPIEAEARATEVKKYGLKPVGAFFLSVMHDPDFD
PIPMVNKELDAFEAAGGDYLILATDSGRDGYDDRPVLDEAGWKTLFTNLDQIREVCASRNVTACLHPHWGTMVQNRDEVI
RVLENSSIGLCLDTGHLACGGTDVVELVRKYANRVDIVHAKDVHKEMADKLLPGEITWSEGIRAGMFAPIGDGDIDFAAI
VRLLDEAGFDGYYVLEQDIMIDEEPPADDGPIINAKKSYEALASLGR
>Mature_287_residues
MKIAGAPISWGVCEVPNWGYQMTPERVLTEMKQIGLTATEFGPQGWLPIEAEARATEVKKYGLKPVGAFFLSVMHDPDFD
PIPMVNKELDAFEAAGGDYLILATDSGRDGYDDRPVLDEAGWKTLFTNLDQIREVCASRNVTACLHPHWGTMVQNRDEVI
RVLENSSIGLCLDTGHLACGGTDVVELVRKYANRVDIVHAKDVHKEMADKLLPGEITWSEGIRAGMFAPIGDGDIDFAAI
VRLLDEAGFDGYYVLEQDIMIDEEPPADDGPIINAKKSYEALASLGR

Specific function: Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D- (3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iolE/mocC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013022
- InterPro:   IPR012307 [H]

Pfam domain/function: PF01261 AP_endonuc_2 [H]

EC number: =4.2.1.44 [H]

Molecular weight: Translated: 31555; Mature: 31555

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAGAPISWGVCEVPNWGYQMTPERVLTEMKQIGLTATEFGPQGWLPIEAEARATEVKK
CCCCCCCCCCCEECCCCCCCEECHHHHHHHHHHHCCCCCCCCCCCCEEECCCCHHHHHHH
YGLKPVGAFFLSVMHDPDFDPIPMVNKELDAFEAAGGDYLILATDSGRDGYDDRPVLDEA
HCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHC
GWKTLFTNLDQIREVCASRNVTACLHPHWGTMVQNRDEVIRVLENSSIGLCLDTGHLACG
CHHHHHHCHHHHHHHHHCCCCEEEECCCCCHHHCCHHHHHHHHHCCCCEEEEECCCCCCC
GTDVVELVRKYANRVDIVHAKDVHKEMADKLLPGEITWSEGIRAGMFAPIGDGDIDFAAI
CHHHHHHHHHHHHHEEEEEHHHHHHHHHHHCCCCCEEHHHCCCCCCCCCCCCCCCCHHHH
VRLLDEAGFDGYYVLEQDIMIDEEPPADDGPIINAKKSYEALASLGR
HHHHHHCCCCCEEEEEECEEECCCCCCCCCCEECCHHHHHHHHHCCC
>Mature Secondary Structure
MKIAGAPISWGVCEVPNWGYQMTPERVLTEMKQIGLTATEFGPQGWLPIEAEARATEVKK
CCCCCCCCCCCEECCCCCCCEECHHHHHHHHHHHCCCCCCCCCCCCEEECCCCHHHHHHH
YGLKPVGAFFLSVMHDPDFDPIPMVNKELDAFEAAGGDYLILATDSGRDGYDDRPVLDEA
HCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHC
GWKTLFTNLDQIREVCASRNVTACLHPHWGTMVQNRDEVIRVLENSSIGLCLDTGHLACG
CHHHHHHCHHHHHHHHHCCCCEEEECCCCCHHHCCHHHHHHHHHCCCCEEEEECCCCCCC
GTDVVELVRKYANRVDIVHAKDVHKEMADKLLPGEITWSEGIRAGMFAPIGDGDIDFAAI
CHHHHHHHHHHHHHEEEEEHHHHHHHHHHHCCCCCEEHHHCCCCCCCCCCCCCCCCHHHH
VRLLDEAGFDGYYVLEQDIMIDEEPPADDGPIINAKKSYEALASLGR
HHHHHHCCCCCEEEEEECEEECCCCCCCCCCEECCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA