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The map label for this gene is cobL [H]

Identifier: 50841919

GI number: 50841919

Start: 479791

End: 480387

Strand: Reverse

Name: cobL [H]

Synonym: PPA0436

Alternate gene names: 50841919

Gene position: 480387-479791 (Counterclockwise)

Preceding gene: 161621799

Following gene: 50841913

Centisome position: 18.76

GC content: 64.32

Gene sequence:

>597_bases
ATGACCCACGATCCTGATACCTCTCTCCTCGGACGTACCCCTGGCCTGGCCGAGGAGCACTTCGCCCACGACGGGCTCAT
CACCAAGCACGCGGTACGAGCCGTTGCGCTGGCAGCCCTGCGGCCCATGCCTGGTCAACTGTTATGGGACCTCGGTACCG
GAGCCGGGTCAATCGCGGTCGAATGGTGCCGCACTGACCCAACCTGTCGGGCGATCGGGCTGGAACGCAAGGCTGAGCGG
GCCGCCAACGCACGTACTAACGCGTCCGAACTCACCCTTCCGGGCCAGTTCGACGTGATCGACGCCGATCTGGCAAAGGG
ACTGCCCGAGGGGCTTCCTGACCCCGACGCAGTGTTCATCGGCGGTGGAGCCACCAAGGCCCTGGTGAATCAGTGCCGGC
CACGACTTCCCATCGGCGGTCGGCTCGTCGTTCACGGTGTCACTATGGAGGCCGAAATGCTAGTGGAGACCCTGCACTGT
GACCTAGGCGGTGATCTCATCAGGTTCGGAGTCGAAACCGCCGATGTCATCGGTCGGTTACACGGCTGGAAGCCAGCCCG
CACCGTCGTGGCGTGGACCTGGCAACGCACTGAGTGA

Upstream 100 bases:

>100_bases
CCGCGAGTCCCCTTGATTGTGTCACACGGGCTTCGGCTCCCCCACCCCGCGTTGGCCCGGATCCGGGGGGCCAGCTTGCG
CACTGGCCTAGGCTTCACCC

Downstream 100 bases:

>100_bases
CATGCCCGGCTACCCCCACTGCGGACTCAGCTGATCTGGGAAGCGAGTAAGCAGGCAGCCCGCATCTGCTCGGCGGTGGG
ACGCACGTGGCGCGATGCCG

Product: precorrin 8 decarboxylase CbiT

Products: NA

Alternate protein names: Precorrin-6 methyltransferase; Precorrin-6Y methylase [H]

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MTHDPDTSLLGRTPGLAEEHFAHDGLITKHAVRAVALAALRPMPGQLLWDLGTGAGSIAVEWCRTDPTCRAIGLERKAER
AANARTNASELTLPGQFDVIDADLAKGLPEGLPDPDAVFIGGGATKALVNQCRPRLPIGGRLVVHGVTMEAEMLVETLHC
DLGGDLIRFGVETADVIGRLHGWKPARTVVAWTWQRTE

Sequences:

>Translated_198_residues
MTHDPDTSLLGRTPGLAEEHFAHDGLITKHAVRAVALAALRPMPGQLLWDLGTGAGSIAVEWCRTDPTCRAIGLERKAER
AANARTNASELTLPGQFDVIDADLAKGLPEGLPDPDAVFIGGGATKALVNQCRPRLPIGGRLVVHGVTMEAEMLVETLHC
DLGGDLIRFGVETADVIGRLHGWKPARTVVAWTWQRTE
>Mature_197_residues
THDPDTSLLGRTPGLAEEHFAHDGLITKHAVRAVALAALRPMPGQLLWDLGTGAGSIAVEWCRTDPTCRAIGLERKAERA
ANARTNASELTLPGQFDVIDADLAKGLPEGLPDPDAVFIGGGATKALVNQCRPRLPIGGRLVVHGVTMEAEMLVETLHCD
LGGDLIRFGVETADVIGRLHGWKPARTVVAWTWQRTE

Specific function: Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X [H]

COG id: COG2242

COG function: function code H; Precorrin-6B methylase 2

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012818
- InterPro:   IPR014008
- InterPro:   IPR006365 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.132 [H]

Molecular weight: Translated: 21221; Mature: 21089

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHDPDTSLLGRTPGLAEEHFAHDGLITKHAVRAVALAALRPMPGQLLWDLGTGAGSIAV
CCCCCCCCHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEE
EWCRTDPTCRAIGLERKAERAANARTNASELTLPGQFDVIDADLAKGLPEGLPDPDAVFI
EEECCCCCEEHHCCHHHHHHHHCCCCCCCCEECCCCCCEECHHHHCCCCCCCCCCCEEEE
GGGATKALVNQCRPRLPIGGRLVVHGVTMEAEMLVETLHCDLGGDLIRFGVETADVIGRL
CCCHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHH
HGWKPARTVVAWTWQRTE
CCCCCCCEEEEEEEECCC
>Mature Secondary Structure 
THDPDTSLLGRTPGLAEEHFAHDGLITKHAVRAVALAALRPMPGQLLWDLGTGAGSIAV
CCCCCCCHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEE
EWCRTDPTCRAIGLERKAERAANARTNASELTLPGQFDVIDADLAKGLPEGLPDPDAVFI
EEECCCCCEEHHCCHHHHHHHHCCCCCCCCEECCCCCCEECHHHHCCCCCCCCCCCEEEE
GGGATKALVNQCRPRLPIGGRLVVHGVTMEAEMLVETLHCDLGGDLIRFGVETADVIGRL
CCCHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHH
HGWKPARTVVAWTWQRTE
CCCCCCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]