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The map label for this gene is sdaA [H]

Identifier: 50841879

GI number: 50841879

Start: 440439

End: 441875

Strand: Reverse

Name: sdaA [H]

Synonym: PPA0396

Alternate gene names: 50841879

Gene position: 441875-440439 (Counterclockwise)

Preceding gene: 50841886

Following gene: 50841878

Centisome position: 17.26

GC content: 63.05

Gene sequence:

>1437_bases
ATGTCTGTGGCAGTCAGCGTTTTCGATATCTTCAAGGTCGGCATCGGTCCGTCTAGTTCTCATACCGTCGGCCCCATGCG
AGCCGCCCGGATTTTCGTGACTGATCTGGCTCAGTCACCGGTATGGCCTGAGGTCACCCGCGTGCGTGCGGAGCTCTTCG
GCTCGTTGGGAGCGACCGGGCACGGACACGGGTCTGAGGCCGCCGTCTTGCTGGGTCTGGAAGGCGAAGATCCGGCCACC
GTCGACACGGATCAGACTCCGGCTCGAGCCGCGTCTATCGCCAATGATGGCCGTATCACTCTGGATGCTGTCCATGGCGG
TCGGGAGATTTCCTTTGACGTCACGACCGACCTTGTCCTTCACCGCAACCGGTCCCTCCCTTTTCATCCCAACGGCATGA
CGTTCACCGCCTGGTCTGGCCAGGAAGTCGTGGTCGAGCGCACTTTCTACTCCATCGGCGGCGGTTTTGTCGTTGAGCAC
GGAGAGGACGAGCACCCCGCCATCGTGCGCGACTCGGCACCGGTCCCTTACCCTTTCAAGACCGGCAAGGAACTTCTCGA
GCAGTGCTCGGACTATCGGATGAGCATCCCCGAAGTCGCAATGGCCAATGAGATGACCCTCCGTGCAGAGGAGGAAATAC
GCGGCCAGCTCCTCGACATCTGGGCAGTCATGCACGCCTGCGTCGAGCGCGGCTGCTCGCGCGCCGGCGTTCTTCCGGGC
GGTCTGCATGTGCGCCGCCGCGCCATGAAGATGCACCACGATCTTGTCACCCGGGAGCGGATCACCCCGGGCAAGCCGGA
ACCATTCGGCTCGGTTGACTGGCTAACAGTGTGGGCGTTGGCAGTCAATGAGGAGAACGCCGCGGGTGGACGTATTGTTA
CCGCCCCTACCAACGGCGCGGCCGGCATCATCCCGTCCTGCCTGCACTTTGCGGTGAAGTTCCTCTCCCCCGGTTCGGAC
ATCGATTCGGGCACTCCTGGCGTCGACACCGGTGATGACGACCTCATCGTCAATTATCTGCTAGCGGCCGGCGCCGTCGG
GGAGATCTACCAACAGTCCGCATCGATCTCTGGGGCCGAGGTCGGCTGCCAGGGCGAGGTCGGCGTGGCCTGCTCGATGG
CTGCGGCTGGTCTAGCTCAGGTCATGGGCGGGACGCCGACCCAGGTCTGCAACGCCGCCGAGATTGGCCTAGAGCACCAC
CTCGGGCTCACCTGCGACCCCGTCGGGGGCCTAGTACAGATCCCGTGCATTGAACGCAACGCCCTTGGTGCTATCAAGGC
CGTCACAGCTGCCCGCCTAGCCATGGCTGGGGACGGCTCCCAGATCGTCAGTCTGGATCAGGTCATGAAGACGATGATGG
AGACCGGACGCGACATGAAGGTCAAATACAAGGAGACGGCGCGCGGTGGGTTGGCCGTGAATATCGTCGAGTGCTAG

Upstream 100 bases:

>100_bases
AGGTTCGAGAGCCTTGGTCTATTCGGTTCGCGAACCATGCTTCACCGTGAACCGACACAACCTCTTTGGACAACATTCCA
GCCCCGGGTTTGGCAGAATC

Downstream 100 bases:

>100_bases
CAGCTCGGCGCATTGGCAACGCGAGTGCTAGCAGCTCGGCGCATTGGCAACGCGAGTGCTAGCAGCTCGGCGCATCGAGG
GGCCGGGATTGGCGGTTCAA

Product: L-serine dehydratase

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 478; Mature: 477

Protein sequence:

>478_residues
MSVAVSVFDIFKVGIGPSSSHTVGPMRAARIFVTDLAQSPVWPEVTRVRAELFGSLGATGHGHGSEAAVLLGLEGEDPAT
VDTDQTPARAASIANDGRITLDAVHGGREISFDVTTDLVLHRNRSLPFHPNGMTFTAWSGQEVVVERTFYSIGGGFVVEH
GEDEHPAIVRDSAPVPYPFKTGKELLEQCSDYRMSIPEVAMANEMTLRAEEEIRGQLLDIWAVMHACVERGCSRAGVLPG
GLHVRRRAMKMHHDLVTRERITPGKPEPFGSVDWLTVWALAVNEENAAGGRIVTAPTNGAAGIIPSCLHFAVKFLSPGSD
IDSGTPGVDTGDDDLIVNYLLAAGAVGEIYQQSASISGAEVGCQGEVGVACSMAAAGLAQVMGGTPTQVCNAAEIGLEHH
LGLTCDPVGGLVQIPCIERNALGAIKAVTAARLAMAGDGSQIVSLDQVMKTMMETGRDMKVKYKETARGGLAVNIVEC

Sequences:

>Translated_478_residues
MSVAVSVFDIFKVGIGPSSSHTVGPMRAARIFVTDLAQSPVWPEVTRVRAELFGSLGATGHGHGSEAAVLLGLEGEDPAT
VDTDQTPARAASIANDGRITLDAVHGGREISFDVTTDLVLHRNRSLPFHPNGMTFTAWSGQEVVVERTFYSIGGGFVVEH
GEDEHPAIVRDSAPVPYPFKTGKELLEQCSDYRMSIPEVAMANEMTLRAEEEIRGQLLDIWAVMHACVERGCSRAGVLPG
GLHVRRRAMKMHHDLVTRERITPGKPEPFGSVDWLTVWALAVNEENAAGGRIVTAPTNGAAGIIPSCLHFAVKFLSPGSD
IDSGTPGVDTGDDDLIVNYLLAAGAVGEIYQQSASISGAEVGCQGEVGVACSMAAAGLAQVMGGTPTQVCNAAEIGLEHH
LGLTCDPVGGLVQIPCIERNALGAIKAVTAARLAMAGDGSQIVSLDQVMKTMMETGRDMKVKYKETARGGLAVNIVEC
>Mature_477_residues
SVAVSVFDIFKVGIGPSSSHTVGPMRAARIFVTDLAQSPVWPEVTRVRAELFGSLGATGHGHGSEAAVLLGLEGEDPATV
DTDQTPARAASIANDGRITLDAVHGGREISFDVTTDLVLHRNRSLPFHPNGMTFTAWSGQEVVVERTFYSIGGGFVVEHG
EDEHPAIVRDSAPVPYPFKTGKELLEQCSDYRMSIPEVAMANEMTLRAEEEIRGQLLDIWAVMHACVERGCSRAGVLPGG
LHVRRRAMKMHHDLVTRERITPGKPEPFGSVDWLTVWALAVNEENAAGGRIVTAPTNGAAGIIPSCLHFAVKFLSPGSDI
DSGTPGVDTGDDDLIVNYLLAAGAVGEIYQQSASISGAEVGCQGEVGVACSMAAAGLAQVMGGTPTQVCNAAEIGLEHHL
GLTCDPVGGLVQIPCIERNALGAIKAVTAARLAMAGDGSQIVSLDQVMKTMMETGRDMKVKYKETARGGLAVNIVEC

Specific function: Deaminates Also Threonine, Particularly When It Is Present In High Concentration. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1788116, Length=474, Percent_Identity=49.789029535865, Blast_Score=468, Evalue=1e-133,
Organism=Escherichia coli, GI1789161, Length=476, Percent_Identity=49.7899159663866, Blast_Score=462, Evalue=1e-131,
Organism=Escherichia coli, GI48994925, Length=473, Percent_Identity=49.8942917547569, Blast_Score=460, Evalue=1e-131,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 50414; Mature: 50283

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVAVSVFDIFKVGIGPSSSHTVGPMRAARIFVTDLAQSPVWPEVTRVRAELFGSLGATG
CCEEEEEHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCC
HGHGSEAAVLLGLEGEDPATVDTDQTPARAASIANDGRITLDAVHGGREISFDVTTDLVL
CCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHCCCCCCEEEEEECCCEEEEEEEEEEEEE
HRNRSLPFHPNGMTFTAWSGQEVVVERTFYSIGGGFVVEHGEDEHPAIVRDSAPVPYPFK
ECCCCCCCCCCCCEEEEECCCEEEEEEEHHHCCCCEEEECCCCCCCEEEECCCCCCCCCH
TGKELLEQCSDYRMSIPEVAMANEMTLRAEEEIRGQLLDIWAVMHACVERGCSRAGVLPG
HHHHHHHHHHHHCCCCCCHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GLHVRRRAMKMHHDLVTRERITPGKPEPFGSVDWLTVWALAVNEENAAGGRIVTAPTNGA
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCEEEECCCCCC
AGIIPSCLHFAVKFLSPGSDIDSGTPGVDTGDDDLIVNYLLAAGAVGEIYQQSASISGAE
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHCCCCCCC
VGCQGEVGVACSMAAAGLAQVMGGTPTQVCNAAEIGLEHHLGLTCDPVGGLVQIPCIERN
CCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCHHHCCCCEECCCCCEEEECEECCC
ALGAIKAVTAARLAMAGDGSQIVSLDQVMKTMMETGRDMKVKYKETARGGLAVNIVEC
HHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHCCCCEEEEEHHCCCCCEEEEEEEC
>Mature Secondary Structure 
SVAVSVFDIFKVGIGPSSSHTVGPMRAARIFVTDLAQSPVWPEVTRVRAELFGSLGATG
CEEEEEHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCC
HGHGSEAAVLLGLEGEDPATVDTDQTPARAASIANDGRITLDAVHGGREISFDVTTDLVL
CCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHCCCCCCEEEEEECCCEEEEEEEEEEEEE
HRNRSLPFHPNGMTFTAWSGQEVVVERTFYSIGGGFVVEHGEDEHPAIVRDSAPVPYPFK
ECCCCCCCCCCCCEEEEECCCEEEEEEEHHHCCCCEEEECCCCCCCEEEECCCCCCCCCH
TGKELLEQCSDYRMSIPEVAMANEMTLRAEEEIRGQLLDIWAVMHACVERGCSRAGVLPG
HHHHHHHHHHHHCCCCCCHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GLHVRRRAMKMHHDLVTRERITPGKPEPFGSVDWLTVWALAVNEENAAGGRIVTAPTNGA
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCEEEECCCCCC
AGIIPSCLHFAVKFLSPGSDIDSGTPGVDTGDDDLIVNYLLAAGAVGEIYQQSASISGAE
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHCCCCCCC
VGCQGEVGVACSMAAAGLAQVMGGTPTQVCNAAEIGLEHHLGLTCDPVGGLVQIPCIERN
CCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCHHHCCCCEECCCCCEEEECEECCC
ALGAIKAVTAARLAMAGDGSQIVSLDQVMKTMMETGRDMKVKYKETARGGLAVNIVEC
HHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHCCCCEEEEEHHCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]