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The map label for this gene is ptsH [C]

Identifier: 50841630

GI number: 50841630

Start: 169304

End: 169561

Strand: Reverse

Name: ptsH [C]

Synonym: PPA0141

Alternate gene names: 50841630

Gene position: 169561-169304 (Counterclockwise)

Preceding gene: 50841631

Following gene: 50841622

Centisome position: 6.62

GC content: 62.79

Gene sequence:

>258_bases
ATGGCCAGCAAAACCGTTAAGGTCGGATCCTCTGTCGGACTCCACGCCCGCCCCGCCGCCGTCATCTCGCAGGAGGCTGC
CAAGCTCAGTTCAACCGTCACCCTAGCTGCCGAGGGAGGCGAGCCAATTGACGCCAAGTCCGTGCTGCTCATCATGACCC
TCGGTGCCAGCGCAGGCGACCCAGTGACAGTCGCCAGCGATAACGAGGACGACGTCAACACCATTGCCGACCTGGTTGCC
TCTAACCTCGACGCCTGA

Upstream 100 bases:

>100_bases
TGGCAGCCTTGCTCGTAACCGCTCTCAAAGCCTCAGCTCGGCGCAAGGCCGCGGCTGCCGCGTAAAATTTCCACACCACA
ACCCCGAAAGGAACACCATC

Downstream 100 bases:

>100_bases
GCCAGCCTCCACGATGGGGCCGCTGCCATCGTGACTCGGCCCCACAGGCACCAATGTCGAACCTCAAAAAGTGGCCACCG
ATCCGGAGTCGACGCGGTAG

Product: hypothetical protein

Products: D-sorbitol 6-phosphate [Cytoplasm]; pyruvate; alpha,alpha-trehalose 6-phosphate [Cytoplasm]; mannitol-1-phosphate [Cytoplasm]; D-glucosamine-6-phosphate [Cytoplasm]; N-acetyl-D-glucosamine-6-phosphate [Cytoplasm]; mannose-6-phosphate [Cytoplasm]; galactitol-1-phosphate [Cytoplasm]; fructose-6-phosphate [Cytoplasm]; fructose-1-phosphate [Cytoplasm]; glucose-6-phosphate [Cytoplasm]; mannitol-1-phosphate [Cytoplasm]; diacetylchitobiose-6-phosphate [Cytoplasm]; cellobiose-6-phosphate [Cytoplasm]; salicin-6-phosphate [Cytoplasm]; arbutin-6-phosphate [Cytoplasm] [C]

Alternate protein names: Phosphocarrier Protein HPr; Phosphotransferase System HPr Family Protein; Phosphocarrier HPr Family; Phosphocarrier Protein; HPr Family Phosphocarrier Protein; Carbohydrate Carrier Protein; PTS Phosphohistidine-Containing Protein

Number of amino acids: Translated: 85; Mature: 84

Protein sequence:

>85_residues
MASKTVKVGSSVGLHARPAAVISQEAAKLSSTVTLAAEGGEPIDAKSVLLIMTLGASAGDPVTVASDNEDDVNTIADLVA
SNLDA

Sequences:

>Translated_85_residues
MASKTVKVGSSVGLHARPAAVISQEAAKLSSTVTLAAEGGEPIDAKSVLLIMTLGASAGDPVTVASDNEDDVNTIADLVA
SNLDA
>Mature_84_residues
ASKTVKVGSSVGLHARPAAVISQEAAKLSSTVTLAAEGGEPIDAKSVLLIMTLGASAGDPVTVASDNEDDVNTIADLVAS
NLDA

Specific function: This Is A Component Of The Phosphoenolpyruvate-Dependent Sugar Phosphotransferase System (Pts), A Major Carbohydrate Active -Transport System. The Phosphoryl Group From Phosphoenolpyruvate (Pep) Is Transferred To The Phosphoryl Carrier Protein Hpr By Enz

COG id: COG1925

COG function: function code G; Phosphotransferase system, HPr-related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 4180 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 2100 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 3235 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 8405; Mature: 8274

Theoretical pI: Translated: 4.09; Mature: 4.09

Prosite motif: PS00369 PTS_HPR_HIS ; PS00589 PTS_HPR_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASKTVKVGSSVGLHARPAAVISQEAAKLSSTVTLAAEGGEPIDAKSVLLIMTLGASAGD
CCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEEEECCCCCC
PVTVASDNEDDVNTIADLVASNLDA
CEEEECCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ASKTVKVGSSVGLHARPAAVISQEAAKLSSTVTLAAEGGEPIDAKSVLLIMTLGASAGD
CCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEEEECCCCCC
PVTVASDNEDDVNTIADLVASNLDA
CEEEECCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: sorbitol [Periplasm]; phosphoenolpyruvate; trehalose [Periplasm]; mannitol [Periplasm]; glucosamine [Periplasm]; N-acetyl-D-glucosamine [Periplasm]; mannose [Periplasm]; galactitol [Periplasm]; fructose [Periplasm]; beta-D-glucose [Periplasm]; diacetylchitobiose [Periplasm]; cellobiose [Periplasm]; salicin [Periplasm]; arbutin [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + sorbitol [Periplasm] = D-sorbitol 6-phosphate [Cytoplasm] + pyruvate phosphoenolpyruvate + trehalose [Periplasm] = alpha,alpha-trehalose 6-phosphate [Cytoplasm] + pyruvate phosphoenolpyruvate + mannitol [Periplasm] = mannitol-1-phosp

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA