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The map label for this gene is ftsZ [H]

Identifier: 50365210

GI number: 50365210

Start: 451972

End: 453162

Strand: Reverse

Name: ftsZ [H]

Synonym: Mfl392

Alternate gene names: 50365210

Gene position: 453162-451972 (Counterclockwise)

Preceding gene: 50365211

Following gene: 50365209

Centisome position: 57.13

GC content: 34.09

Gene sequence:

>1191_bases
ATGAATAATAATACACAAGAATTTAGCCAAAAAGCCAAGATTAAAGTTATTGGAGTTGGTGGTGGTGGAAACAATGCCGT
TTCAAGAATGTTTGAGCAAGGCGCTCACGGTGTTGATTTCTATATTGCAAATACTGATGCTCAAGTTTTAGCAGGATCAA
ATGTTCCTAATAAAATTATTTTAGGAGAAAAATCAACAAAAGGTTTAGGTGCTGGAGCAAACCCTGAAGTAGGTAAAACA
GCTGCTTTAGAATCTGAAAATGATTTAAGAGCTGCTTTAGAAGGTGCTGATTTAATTTTTGTAACTGCTGGAATGGGTGG
AGGAACTGGAACAGGTGCTGCTCCAGTTATCGCAAGAATCGCTCAAGAAACAGGAGCTTTAGTTGTTGCTATTGTAACTA
AACCATTCAGATTTGAAGGTAAATACAGAAACACTTTTGCAGAAGAAGGAATAATTGAATTAAAAAAATACGTTGATTCA
ACAATTGTTATCTCAAATGATCGCTTATTAGAGTTCATTGGTGCTAAACCTATTCAAGAAGCTTTTGCTGAAGCTGACGC
AATATTAAAACAAGGTGTTCAAACAATTACAGACTTAATTGCAGTTCCTGCTTTAATTAACTTAGACTTTGCTGACGTTA
AAACAGTTATGTCTAAAAAAGGTAACGCATTATTTGGAATTGGTTTAGGAACAGGTCCAGATAAGGCAAACTTAGCAGCT
AATGATGCTATCTCATCAACTTTACTTGAAGCAGCAATCGTTGGTGCAAAAGATGTTATTGTTAATGTTACTGGTGGAGA
AGGTATTTCATTAAACGATGCTTATGATGTTGTTGATGTTGTTAATCAAGCAATTGATAACCCAGAAGTAAATATCGTTT
TTGGAGTAGCTATTAATAAAGAATTAACTGAAAAAGATGAATTAGTTGTAACTGTTATTGCTACTGGTTTTGATGAAGAA
ATGATTAAATCATCAGCAAACTTAGGAACAAAATCAAACGCGGCTTCAACATTTGCAAATTTAAGAACTTCAAGTTTATA
CAAATCAACTCATGTTGAAGAAGAACAAAAAGCACCTACTTCATTTGAAGAAGATGTTCTACATGCTCACCAAACTATGC
ATTCTGTAAATAGTGGTGCATCAACATATTCAGATGATACTGAAGATGATTTCCCAACATTCTTGAAATAG

Upstream 100 bases:

>100_bases
TTGATGATTTTGGTAGTCAAAATCAGGCAAGCGGACAATTATATTTGAAAAATGATGGTATACTAATAGATAAAGTAGAA
GCATAAAAGGAGAAAACAAA

Downstream 100 bases:

>100_bases
TAGGAGAATGAAAATGAAAATTAAAGAACTACTAGATAAAATGAAAACTAAAAAACTTGAATCAGGGGAAATAGATCAAG
CTTTAAACGATGTAAATGGA

Product: cell division protein FtsZ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MNNNTQEFSQKAKIKVIGVGGGGNNAVSRMFEQGAHGVDFYIANTDAQVLAGSNVPNKIILGEKSTKGLGAGANPEVGKT
AALESENDLRAALEGADLIFVTAGMGGGTGTGAAPVIARIAQETGALVVAIVTKPFRFEGKYRNTFAEEGIIELKKYVDS
TIVISNDRLLEFIGAKPIQEAFAEADAILKQGVQTITDLIAVPALINLDFADVKTVMSKKGNALFGIGLGTGPDKANLAA
NDAISSTLLEAAIVGAKDVIVNVTGGEGISLNDAYDVVDVVNQAIDNPEVNIVFGVAINKELTEKDELVVTVIATGFDEE
MIKSSANLGTKSNAASTFANLRTSSLYKSTHVEEEQKAPTSFEEDVLHAHQTMHSVNSGASTYSDDTEDDFPTFLK

Sequences:

>Translated_396_residues
MNNNTQEFSQKAKIKVIGVGGGGNNAVSRMFEQGAHGVDFYIANTDAQVLAGSNVPNKIILGEKSTKGLGAGANPEVGKT
AALESENDLRAALEGADLIFVTAGMGGGTGTGAAPVIARIAQETGALVVAIVTKPFRFEGKYRNTFAEEGIIELKKYVDS
TIVISNDRLLEFIGAKPIQEAFAEADAILKQGVQTITDLIAVPALINLDFADVKTVMSKKGNALFGIGLGTGPDKANLAA
NDAISSTLLEAAIVGAKDVIVNVTGGEGISLNDAYDVVDVVNQAIDNPEVNIVFGVAINKELTEKDELVVTVIATGFDEE
MIKSSANLGTKSNAASTFANLRTSSLYKSTHVEEEQKAPTSFEEDVLHAHQTMHSVNSGASTYSDDTEDDFPTFLK
>Mature_396_residues
MNNNTQEFSQKAKIKVIGVGGGGNNAVSRMFEQGAHGVDFYIANTDAQVLAGSNVPNKIILGEKSTKGLGAGANPEVGKT
AALESENDLRAALEGADLIFVTAGMGGGTGTGAAPVIARIAQETGALVVAIVTKPFRFEGKYRNTFAEEGIIELKKYVDS
TIVISNDRLLEFIGAKPIQEAFAEADAILKQGVQTITDLIAVPALINLDFADVKTVMSKKGNALFGIGLGTGPDKANLAA
NDAISSTLLEAAIVGAKDVIVNVTGGEGISLNDAYDVVDVVNQAIDNPEVNIVFGVAINKELTEKDELVVTVIATGFDEE
MIKSSANLGTKSNAASTFANLRTSSLYKSTHVEEEQKAPTSFEEDVLHAHQTMHSVNSGASTYSDDTEDDFPTFLK

Specific function: This protein is essential to the cell-division process. It seems to assemble into a dynamic ring on the inner surface of the cytoplasmic membrane at the place where division will occur, and the formation of the ring is the signal for septation to begin. B

COG id: COG0206

COG function: function code D; Cell division GTPase

Gene ontology:

Cell location: Cytoplasm. Note=Assembles at the inner surface of the cytoplasmic membrane (By similarity) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsZ family [H]

Homologues:

Organism=Escherichia coli, GI1786284, Length=295, Percent_Identity=50.8474576271186, Blast_Score=236, Evalue=1e-63,

Paralogues:

None

Copy number: 320 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020805
- InterPro:   IPR000158
- InterPro:   IPR008280
- InterPro:   IPR018316
- InterPro:   IPR003008 [H]

Pfam domain/function: PF00091 Tubulin [H]

EC number: NA

Molecular weight: Translated: 41558; Mature: 41558

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: PS01134 FTSZ_1 ; PS01135 FTSZ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNNTQEFSQKAKIKVIGVGGGGNNAVSRMFEQGAHGVDFYIANTDAQVLAGSNVPNKII
CCCCHHHHHCCCEEEEEEECCCCCHHHHHHHHCCCCCEEEEEECCCCEEEECCCCCCEEE
LGEKSTKGLGAGANPEVGKTAALESENDLRAALEGADLIFVTAGMGGGTGTGAAPVIARI
ECCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHH
AQETGALVVAIVTKPFRFEGKYRNTFAEEGIIELKKYVDSTIVISNDRLLEFIGAKPIQE
HHHCCCEEEEEECCCEEECCCHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHCCCHHHH
AFAEADAILKQGVQTITDLIAVPALINLDFADVKTVMSKKGNALFGIGLGTGPDKANLAA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCH
NDAISSTLLEAAIVGAKDVIVNVTGGEGISLNDAYDVVDVVNQAIDNPEVNIVFGVAINK
HHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEECC
ELTEKDELVVTVIATGFDEEMIKSSANLGTKSNAASTFANLRTSSLYKSTHVEEEQKAPT
CCCCCCCEEEEEEECCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHCCCC
SFEEDVLHAHQTMHSVNSGASTYSDDTEDDFPTFLK
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHCC
>Mature Secondary Structure
MNNNTQEFSQKAKIKVIGVGGGGNNAVSRMFEQGAHGVDFYIANTDAQVLAGSNVPNKII
CCCCHHHHHCCCEEEEEEECCCCCHHHHHHHHCCCCCEEEEEECCCCEEEECCCCCCEEE
LGEKSTKGLGAGANPEVGKTAALESENDLRAALEGADLIFVTAGMGGGTGTGAAPVIARI
ECCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHH
AQETGALVVAIVTKPFRFEGKYRNTFAEEGIIELKKYVDSTIVISNDRLLEFIGAKPIQE
HHHCCCEEEEEECCCEEECCCHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHCCCHHHH
AFAEADAILKQGVQTITDLIAVPALINLDFADVKTVMSKKGNALFGIGLGTGPDKANLAA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCH
NDAISSTLLEAAIVGAKDVIVNVTGGEGISLNDAYDVVDVVNQAIDNPEVNIVFGVAINK
HHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEECC
ELTEKDELVVTVIATGFDEEMIKSSANLGTKSNAASTFANLRTSSLYKSTHVEEEQKAPT
CCCCCCCEEEEEEECCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHCCCC
SFEEDVLHAHQTMHSVNSGASTYSDDTEDDFPTFLK
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]