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The map label for this gene is yqhT [H]

Identifier: 50365197

GI number: 50365197

Start: 438878

End: 439951

Strand: Reverse

Name: yqhT [H]

Synonym: Mfl379

Alternate gene names: 50365197

Gene position: 439951-438878 (Counterclockwise)

Preceding gene: 50365198

Following gene: 50365196

Centisome position: 55.46

GC content: 27.37

Gene sequence:

>1074_bases
ATGAAAAAACAAGAAATAGTAAATAAATTATTAGAATCAAATTCAGCTGAAGCTATTTTATTTTATTCACCTGAAAATAG
ATATTGATTTTCAAGATTTAAGTCTTCATTAGGTTACTTATTGATAACAAAAACAAAAAGCTATTTATTAGTTGATGGAA
GATATATAACAGCTGCAAGAAATTCAAATAACATTCCAAAAGATATTGAAATAAGAGAATTTTCAAACAATTTATTTGTT
CAAATGAAAGAAATACTAAAAGAACATAATGTTAAAAAATTAGGATTTGAATCTGATTGAGTTCATTATGCAGAATTTGA
AAAATATGCATCTATTTTTACAGAACAAACTTTAGTTCCTATTAATTGTTCAGAAATTAGAATTGTTAAGGATGAATGAG
AAATTGAACAACTACAAAAAGCTTGTGATATAACTAATGAAGTTTTTGAAGCTATTCTTGAATATGTAAAACCAGGAATG
ACTGAAAAAGAATTACAAAGATTCGTTGATAATGAATTTTTAGTAAAAGGTGCTGAAAAAATATCATTTGACACAATCAT
TGCATCTGGTGTTAATGGAAGTATGCCTCATGCTGTTCCAACTGACAAAAAAATTGAAATTGGAGATCTTGTAACTATTG
ATATGGGTTGTTATTACAATGGATATTGCTCAGATCAAACTAGAACTATAGCAATTGGTGAAATAGATGCAAAATTAGAA
GACATTTATAATGCAGTTTATGAAGCACAATCTTTAGGAATAAGTTTAGTTTCAGAAGGTGTTAATGCTGGTGAAATACA
TAAACAAGTTTATGATTTCATTGAAAAAAGAGGATATGGTGGATACTTTACTCATGGTTTAGGTCATGGTTATGGAGTTG
AAATACATGAAGAACCATATGCATCAGCTGCAGGAAATACTATTTTAAAAGAAAACATGACTTTAACAATTGAACCAGGA
ATTTACATTCCAGGTTTAGGTGGAGTTAGAATTGAAGATGATATCTTAGTTTTAAAAGATGGTTATAGAATGCTAACTTC
AGCAACAAGAGAATTAGTAAAACTTAAATTTTAA

Upstream 100 bases:

>100_bases
CTGCAACAAACACGAATTACATAAACAAAAAAAATAGTTTAACTATTTTATTTTTTTTTATTTAATGACAAAATAATATA
TAACAAAACAAGGAGTAAGT

Downstream 100 bases:

>100_bases
TTTAAATGAACCAATGGTTCATTTTTTTATATTTATATAACTTATCAAATTATTAATACTTTATAATTATTATAAATATA
GTTTTGGAGAAAAAAATGTT

Product: Xaa-Pro-dipeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MKKQEIVNKLLESNSAEAILFYSPENRYWFSRFKSSLGYLLITKTKSYLLVDGRYITAARNSNNIPKDIEIREFSNNLFV
QMKEILKEHNVKKLGFESDWVHYAEFEKYASIFTEQTLVPINCSEIRIVKDEWEIEQLQKACDITNEVFEAILEYVKPGM
TEKELQRFVDNEFLVKGAEKISFDTIIASGVNGSMPHAVPTDKKIEIGDLVTIDMGCYYNGYCSDQTRTIAIGEIDAKLE
DIYNAVYEAQSLGISLVSEGVNAGEIHKQVYDFIEKRGYGGYFTHGLGHGYGVEIHEEPYASAAGNTILKENMTLTIEPG
IYIPGLGGVRIEDDILVLKDGYRMLTSATRELVKLKF

Sequences:

>Translated_357_residues
MKKQEIVNKLLESNSAEAILFYSPENRY*FSRFKSSLGYLLITKTKSYLLVDGRYITAARNSNNIPKDIEIREFSNNLFV
QMKEILKEHNVKKLGFESD*VHYAEFEKYASIFTEQTLVPINCSEIRIVKDE*EIEQLQKACDITNEVFEAILEYVKPGM
TEKELQRFVDNEFLVKGAEKISFDTIIASGVNGSMPHAVPTDKKIEIGDLVTIDMGCYYNGYCSDQTRTIAIGEIDAKLE
DIYNAVYEAQSLGISLVSEGVNAGEIHKQVYDFIEKRGYGGYFTHGLGHGYGVEIHEEPYASAAGNTILKENMTLTIEPG
IYIPGLGGVRIEDDILVLKDGYRMLTSATRELVKLKF
>Mature_357_residues
MKKQEIVNKLLESNSAEAILFYSPENRY*FSRFKSSLGYLLITKTKSYLLVDGRYITAARNSNNIPKDIEIREFSNNLFV
QMKEILKEHNVKKLGFESD*VHYAEFEKYASIFTEQTLVPINCSEIRIVKDE*EIEQLQKACDITNEVFEAILEYVKPGM
TEKELQRFVDNEFLVKGAEKISFDTIIASGVNGSMPHAVPTDKKIEIGDLVTIDMGCYYNGYCSDQTRTIAIGEIDAKLE
DIYNAVYEAQSLGISLVSEGVNAGEIHKQVYDFIEKRGYGGYFTHGLGHGYGVEIHEEPYASAAGNTILKENMTLTIEPG
IYIPGLGGVRIEDDILVLKDGYRMLTSATRELVKLKF

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI11559925, Length=252, Percent_Identity=28.5714285714286, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI260593665, Length=343, Percent_Identity=25.9475218658892, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI149589008, Length=310, Percent_Identity=26.4516129032258, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI164420681, Length=231, Percent_Identity=27.2727272727273, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI40385867, Length=209, Percent_Identity=23.9234449760766, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI93141226, Length=370, Percent_Identity=24.3243243243243, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1788728, Length=344, Percent_Identity=34.593023255814, Blast_Score=208, Evalue=5e-55,
Organism=Escherichia coli, GI1789275, Length=252, Percent_Identity=32.1428571428571, Blast_Score=121, Evalue=7e-29,
Organism=Escherichia coli, GI1786364, Length=235, Percent_Identity=29.7872340425532, Blast_Score=96, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17508215, Length=291, Percent_Identity=28.5223367697594, Blast_Score=100, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI71996291, Length=230, Percent_Identity=26.9565217391304, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71989583, Length=258, Percent_Identity=25.968992248062, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6321118, Length=286, Percent_Identity=25.8741258741259, Blast_Score=96, Evalue=8e-21,
Organism=Saccharomyces cerevisiae, GI6320922, Length=268, Percent_Identity=27.2388059701493, Blast_Score=85, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6323273, Length=205, Percent_Identity=29.2682926829268, Blast_Score=83, Evalue=7e-17,
Organism=Drosophila melanogaster, GI21357079, Length=303, Percent_Identity=30.3630363036304, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI19920384, Length=258, Percent_Identity=27.1317829457364, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI21355531, Length=248, Percent_Identity=24.1935483870968, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24583427, Length=167, Percent_Identity=29.3413173652695, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 39910; Mature: 39910

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKQEIVNKLLESNSAEAILFYSPENRYFSRFKSSLGYLLITKTKSYLLVDGRYITAARN
CCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHCCCEEEEEECCCEEEECCEEEEEECC
SNNIPKDIEIREFSNNLFVQMKEILKEHNVKKLGFESDVHYAEFEKYASIFTEQTLVPIN
CCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEC
CSEIRIVKDEEIEQLQKACDITNEVFEAILEYVKPGMTEKELQRFVDNEFLVKGAEKISF
CCCEEEECHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHEECCCCHHHH
DTIIASGVNGSMPHAVPTDKKIEIGDLVTIDMGCYYNGYCSDQTRTIAIGEIDAKLEDIY
HHHEECCCCCCCCCCCCCCCEEEECCEEEEECCCEECCEECCCCEEEEEECHHHHHHHHH
NAVYEAQSLGISLVSEGVNAGEIHKQVYDFIEKRGYGGYFTHGLGHGYGVEIHEEPYASA
HHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCEEECCCCCCHH
AGNTILKENMTLTIEPGIYIPGLGGVRIEDDILVLKDGYRMLTSATRELVKLKF
CCCEEEECCCEEEECCCEEECCCCCCEEECCEEEEECCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKKQEIVNKLLESNSAEAILFYSPENRYFSRFKSSLGYLLITKTKSYLLVDGRYITAARN
CCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHCCCEEEEEECCCEEEECCEEEEEECC
SNNIPKDIEIREFSNNLFVQMKEILKEHNVKKLGFESDVHYAEFEKYASIFTEQTLVPIN
CCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEC
CSEIRIVKDEEIEQLQKACDITNEVFEAILEYVKPGMTEKELQRFVDNEFLVKGAEKISF
CCCEEEECHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHEECCCCHHHH
DTIIASGVNGSMPHAVPTDKKIEIGDLVTIDMGCYYNGYCSDQTRTIAIGEIDAKLEDIY
HHHEECCCCCCCCCCCCCCCEEEECCEEEEECCCEECCEECCCCEEEEEECHHHHHHHHH
NAVYEAQSLGISLVSEGVNAGEIHKQVYDFIEKRGYGGYFTHGLGHGYGVEIHEEPYASA
HHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCEEECCCCCCHH
AGNTILKENMTLTIEPGIYIPGLGGVRIEDDILVLKDGYRMLTSATRELVKLKF
CCCEEEECCCEEEECCCEEECCCCCCEEECCEEEEECCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]