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The map label for this gene is yrrC [H]

Identifier: 50365138

GI number: 50365138

Start: 377296

End: 379527

Strand: Direct

Name: yrrC [H]

Synonym: Mfl322

Alternate gene names: 50365138

Gene position: 377296-379527 (Clockwise)

Preceding gene: 50365137

Following gene: 50365139

Centisome position: 47.56

GC content: 26.34

Gene sequence:

>2232_bases
ATGAACGAATTATTAACTTTTAGAGGATATGTAGTTAAATATGGTTTTTCAAATGATGCTGGTTGAGGAACTGGTACATT
TGCTAGTGAAGATAATTTAAAACAACATATGAGTATTAAAGGATCAATAACTAGTATGGATAAAAAAACTTTATATGAAA
TAACTGGATATTTTGAAGAACATCCTCGTTATGGTAAAAGTTTTAATGTTCAAACTTATCGAAAAGCACCTATTCACTCA
ACTAAAGAACAAATTAAATTTTTAGCAGGTCCTGCATTTCCAGGTGTAGGAGAAAAAACAGCTGAAATTATAATAAATCA
CTTAGGTGATAAAGCAATTACACAATTAGTTAAAAATATTGAATTATTAAATGAAATACCAGGACTTAATGCTATTTATA
TCCCAATTATTAAAAAAGGAATAGAAGAGAATATCAGACAAGAAGGTCAAGAAAGATTAAGATATATCTTTTTTGAAAAT
AATCTTAAAACTTCAATATTAGATTGAATGGATAATCACTTTGATCAAGATAATGACATTATTGAAAGCATTTTTTCAAA
TTCATTTTTATCTTTTGCAAAAGATAAAGAAATTGCTTCATTTGAAGAACTTGATAAAGTTGCTGTTCATTTTGGATTAG
AATTACACTCACCTGAAAGAATAGCTTATTGAGCTTGAAAGTTAGCTGATGATTTTTTATTTGCATCTGGAGATACTTAT
ACAAACAAAGATTATCTTTCAAGAAGTTTAATGCGTAAGTTAAAAATACAAGATACCGAATTACTTTTTGAAGGTATTTT
ATATGCTAAAGAAAAAGGTATTTTAAAATTAACTAAAAATCGTATTTATACAGAAGAATCTTGAAGAGAAGAGCAAATTA
TCGCAGATAATATAATAAAGCTTAATATACCCACTAAAAATGCCAATAAAGAAGGTATTTCATGAGAAATAAATCAAATT
GAAGAAGAAATAGCTTATGAAAATAAAATTAAAGATTTTAAATTTGATGAAAAACAAAGAGAAGCATTAGAATTATTTGC
CAATAATAAATTATCTATTATTACTGGTGGACCAGGAACTGGTAAAACAACATTGATTAAAGGAATAGTTAAATTGTTTA
ATCGTATGAGTGGTACTGAGGACTATGCAATAGCAACACCAACCGGAAGAGCTGCTGCTAGAATTAGAGAAACATACAAG
AAATCATATGCAACAACAATACACAAACTATTAGAAGCAAAAGAACTTAATAAGTTTCAAATTACACAAAATAATCCATT
AAATCAAAAACTTGTAATTTTAGATGAATGCTCAATGATAGATAATAAATTATTTGCAAGTTTTATACAATCTTGTGATC
GAGTTAGAAAAGTAGTTTTAGTTGGTGATGCTAATCAATTACCAAGTGTAGGGTATGGAAATACATTTGCTGATTTATTA
GAACTAGATTTTTTAAAAACAATTAAACTAGATACAGTTCATAGACAAAAGAATGGCAATGGTATTGTTGATTTAGCTTA
TAAAGTGTTAAATGAGACATTAGAGATAAGTGATTTAGAATCTATGAGTAATGTTGAAATAAACTTTGATTATAATAATC
AAAACACCATGAACAAAGTTACTGAAATTGTTGGTCAACATTGAGATGATTTAGAAAAAAGAGCTAATCATTTACAAGTT
ATTTGTCCAATGTATGGTGGTGAATTAGGAATTGATGAAATCAATGCTCAAATCCAAAATGAATTTAATGAAAATGTTAA
AGATAAAAAGAAAGTCTATGATCGAGGAGATTATCGATTTGTAGTTGAAGATAAAATCATGTTTTTAAAAAATGACACTG
ATTTAGATTTAGCTAATGGTGATGTAGGTAAAATAATTAAAATTAATTATGATGCTATAGGTAGATTAAAAGATGTTTTA
ACTGAATTTAATGATAAAGAGATATTATTACAACCAAAAAACTTTAGTGATGTAAAATTATCTTATGCAACTAGTGTGCA
TAAGACTCAAGGAAGTGAATATAATAATGTTTTATTAGTTATAGATAGTCCTAAATTTAATTCAGGCTTTATTAATAAAA
CATTAATTTACACAGCAGTAACAAGAGCAAAAGATAAAATAGTTATTTTAGGTGATAGTGATTTATTCTTTAATGCAATT
AAAATAACACCACCTAGAAGAAATACAACACTTATTGAAACTATGCTAGAAAAGAGAGAAACAAATGGGTAA

Upstream 100 bases:

>100_bases
AATTTAAGTAAATTTTATAAACAAAGAACTTATTTAAACAAGTTCTTTTTTTGTTTGAGATTTATTTGTTATAAAATATA
TAAATAAAAAGGGTGAGAAG

Downstream 100 bases:

>100_bases
AAAACAAACGTATTTAAAATATTTAGCAACAGCTTCAGGATTATTCTTTTTAAGTTCATTATTGGTTAAATATTTTGATT
TTAAAAAAGGTGTGTTTGAA

Product: exodeoxyribonuclease V

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 743; Mature: 743

Protein sequence:

>743_residues
MNELLTFRGYVVKYGFSNDAGWGTGTFASEDNLKQHMSIKGSITSMDKKTLYEITGYFEEHPRYGKSFNVQTYRKAPIHS
TKEQIKFLAGPAFPGVGEKTAEIIINHLGDKAITQLVKNIELLNEIPGLNAIYIPIIKKGIEENIRQEGQERLRYIFFEN
NLKTSILDWMDNHFDQDNDIIESIFSNSFLSFAKDKEIASFEELDKVAVHFGLELHSPERIAYWAWKLADDFLFASGDTY
TNKDYLSRSLMRKLKIQDTELLFEGILYAKEKGILKLTKNRIYTEESWREEQIIADNIIKLNIPTKNANKEGISWEINQI
EEEIAYENKIKDFKFDEKQREALELFANNKLSIITGGPGTGKTTLIKGIVKLFNRMSGTEDYAIATPTGRAAARIRETYK
KSYATTIHKLLEAKELNKFQITQNNPLNQKLVILDECSMIDNKLFASFIQSCDRVRKVVLVGDANQLPSVGYGNTFADLL
ELDFLKTIKLDTVHRQKNGNGIVDLAYKVLNETLEISDLESMSNVEINFDYNNQNTMNKVTEIVGQHWDDLEKRANHLQV
ICPMYGGELGIDEINAQIQNEFNENVKDKKKVYDRGDYRFVVEDKIMFLKNDTDLDLANGDVGKIIKINYDAIGRLKDVL
TEFNDKEILLQPKNFSDVKLSYATSVHKTQGSEYNNVLLVIDSPKFNSGFINKTLIYTAVTRAKDKIVILGDSDLFFNAI
KITPPRRNTTLIETMLEKRETNG

Sequences:

>Translated_743_residues
MNELLTFRGYVVKYGFSNDAG*GTGTFASEDNLKQHMSIKGSITSMDKKTLYEITGYFEEHPRYGKSFNVQTYRKAPIHS
TKEQIKFLAGPAFPGVGEKTAEIIINHLGDKAITQLVKNIELLNEIPGLNAIYIPIIKKGIEENIRQEGQERLRYIFFEN
NLKTSILD*MDNHFDQDNDIIESIFSNSFLSFAKDKEIASFEELDKVAVHFGLELHSPERIAY*A*KLADDFLFASGDTY
TNKDYLSRSLMRKLKIQDTELLFEGILYAKEKGILKLTKNRIYTEES*REEQIIADNIIKLNIPTKNANKEGIS*EINQI
EEEIAYENKIKDFKFDEKQREALELFANNKLSIITGGPGTGKTTLIKGIVKLFNRMSGTEDYAIATPTGRAAARIRETYK
KSYATTIHKLLEAKELNKFQITQNNPLNQKLVILDECSMIDNKLFASFIQSCDRVRKVVLVGDANQLPSVGYGNTFADLL
ELDFLKTIKLDTVHRQKNGNGIVDLAYKVLNETLEISDLESMSNVEINFDYNNQNTMNKVTEIVGQH*DDLEKRANHLQV
ICPMYGGELGIDEINAQIQNEFNENVKDKKKVYDRGDYRFVVEDKIMFLKNDTDLDLANGDVGKIIKINYDAIGRLKDVL
TEFNDKEILLQPKNFSDVKLSYATSVHKTQGSEYNNVLLVIDSPKFNSGFINKTLIYTAVTRAKDKIVILGDSDLFFNAI
KITPPRRNTTLIETMLEKRETNG
>Mature_743_residues
MNELLTFRGYVVKYGFSNDAG*GTGTFASEDNLKQHMSIKGSITSMDKKTLYEITGYFEEHPRYGKSFNVQTYRKAPIHS
TKEQIKFLAGPAFPGVGEKTAEIIINHLGDKAITQLVKNIELLNEIPGLNAIYIPIIKKGIEENIRQEGQERLRYIFFEN
NLKTSILD*MDNHFDQDNDIIESIFSNSFLSFAKDKEIASFEELDKVAVHFGLELHSPERIAY*A*KLADDFLFASGDTY
TNKDYLSRSLMRKLKIQDTELLFEGILYAKEKGILKLTKNRIYTEES*REEQIIADNIIKLNIPTKNANKEGIS*EINQI
EEEIAYENKIKDFKFDEKQREALELFANNKLSIITGGPGTGKTTLIKGIVKLFNRMSGTEDYAIATPTGRAAARIRETYK
KSYATTIHKLLEAKELNKFQITQNNPLNQKLVILDECSMIDNKLFASFIQSCDRVRKVVLVGDANQLPSVGYGNTFADLL
ELDFLKTIKLDTVHRQKNGNGIVDLAYKVLNETLEISDLESMSNVEINFDYNNQNTMNKVTEIVGQH*DDLEKRANHLQV
ICPMYGGELGIDEINAQIQNEFNENVKDKKKVYDRGDYRFVVEDKIMFLKNDTDLDLANGDVGKIIKINYDAIGRLKDVL
TEFNDKEILLQPKNFSDVKLSYATSVHKTQGSEYNNVLLVIDSPKFNSGFINKTLIYTAVTRAKDKIVILGDSDLFFNAI
KITPPRRNTTLIETMLEKRETNG

Specific function: Exhibits Several Catalytic Activities, Including ATP-Dependent Exonuclease, ATP-Stimulated Endonuclease, ATP-Dependent Unwinding And DNA-Dependent ATPase Activities. Strand Cleavage Occurs 5' To 3' During The Unwinding Of Duplex DNA At Chi Sequences, Whi

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789182, Length=459, Percent_Identity=25.0544662309368, Blast_Score=105, Evalue=8e-24,
Organism=Saccharomyces cerevisiae, GI6321820, Length=299, Percent_Identity=25.0836120401338, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR006345 [H]

Pfam domain/function: NA

EC number: 3.1.11.5

Molecular weight: Translated: 83559; Mature: 83559

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNELLTFRGYVVKYGFSNDAGGTGTFASEDNLKQHMSIKGSITSMDKKTLYEITGYFEEH
CCCCEEECCEEEEECCCCCCCCCCCCCCCCCHHHHHEECCCCCCCCHHHHHHHHHHHHHC
PRYGKSFNVQTYRKAPIHSTKEQIKFLAGPAFPGVGEKTAEIIINHLGDKAITQLVKNIE
CCCCCCCCCCEEECCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHH
LLNEIPGLNAIYIPIIKKGIEENIRQEGQERLRYIFFENNLKTSILDMDNHFDQDNDIIE
HHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHEEEEEEECCCCEEEEECCCCCCCCHHHHH
SIFSNSFLSFAKDKEIASFEELDKVAVHFGLELHSPERIAYAKLADDFLFASGDTYTNKD
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHCEEECCCCHHHHHHHHHHHEEECCCCCCCHH
YLSRSLMRKLKIQDTELLFEGILYAKEKGILKLTKNRIYTEESREEQIIADNIIKLNIPT
HHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCHHHHCCEEEEECCC
KNANKEGISEINQIEEEIAYENKIKDFKFDEKQREALELFANNKLSIITGGPGTGKTTLI
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCHHHHH
KGIVKLFNRMSGTEDYAIATPTGRAAARIRETYKKSYATTIHKLLEAKELNKFQITQNNP
HHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
LNQKLVILDECSMIDNKLFASFIQSCDRVRKVVLVGDANQLPSVGYGNTFADLLELDFLK
CCCEEEEEECHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCCHHHHHHHHHHHH
TIKLDTVHRQKNGNGIVDLAYKVLNETLEISDLESMSNVEINFDYNNQNTMNKVTEIVGQ
HHHHHHHHHCCCCCCHHHHHHHHHHHHHCHHHHHCCCCEEEEEECCCCHHHHHHHHHHCC
HDDLEKRANHLQVICPMYGGELGIDEINAQIQNEFNENVKDKKKVYDRGDYRFVVEDKIM
CCCHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEEEECEEE
FLKNDTDLDLANGDVGKIIKINYDAIGRLKDVLTEFNDKEILLQPKNFSDVKLSYATSVH
EEECCCCCEECCCCCCCEEEECHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEHHHHHH
KTQGSEYNNVLLVIDSPKFNSGFINKTLIYTAVTRAKDKIVILGDSDLFFNAIKITPPRR
HCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCEEEEEEEECCCCC
NTTLIETMLEKRETNG
CHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNELLTFRGYVVKYGFSNDAGGTGTFASEDNLKQHMSIKGSITSMDKKTLYEITGYFEEH
CCCCEEECCEEEEECCCCCCCCCCCCCCCCCHHHHHEECCCCCCCCHHHHHHHHHHHHHC
PRYGKSFNVQTYRKAPIHSTKEQIKFLAGPAFPGVGEKTAEIIINHLGDKAITQLVKNIE
CCCCCCCCCCEEECCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHH
LLNEIPGLNAIYIPIIKKGIEENIRQEGQERLRYIFFENNLKTSILDMDNHFDQDNDIIE
HHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHEEEEEEECCCCEEEEECCCCCCCCHHHHH
SIFSNSFLSFAKDKEIASFEELDKVAVHFGLELHSPERIAYAKLADDFLFASGDTYTNKD
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHCEEECCCCHHHHHHHHHHHEEECCCCCCCHH
YLSRSLMRKLKIQDTELLFEGILYAKEKGILKLTKNRIYTEESREEQIIADNIIKLNIPT
HHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCHHHHCCEEEEECCC
KNANKEGISEINQIEEEIAYENKIKDFKFDEKQREALELFANNKLSIITGGPGTGKTTLI
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCHHHHH
KGIVKLFNRMSGTEDYAIATPTGRAAARIRETYKKSYATTIHKLLEAKELNKFQITQNNP
HHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
LNQKLVILDECSMIDNKLFASFIQSCDRVRKVVLVGDANQLPSVGYGNTFADLLELDFLK
CCCEEEEEECHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCCHHHHHHHHHHHH
TIKLDTVHRQKNGNGIVDLAYKVLNETLEISDLESMSNVEINFDYNNQNTMNKVTEIVGQ
HHHHHHHHHCCCCCCHHHHHHHHHHHHHCHHHHHCCCCEEEEEECCCCHHHHHHHHHHCC
HDDLEKRANHLQVICPMYGGELGIDEINAQIQNEFNENVKDKKKVYDRGDYRFVVEDKIM
CCCHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEEEECEEE
FLKNDTDLDLANGDVGKIIKINYDAIGRLKDVLTEFNDKEILLQPKNFSDVKLSYATSVH
EEECCCCCEECCCCCCCEEEECHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEHHHHHH
KTQGSEYNNVLLVIDSPKFNSGFINKTLIYTAVTRAKDKIVILGDSDLFFNAIKITPPRR
HCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCEEEEEEEECCCCC
NTTLIETMLEKRETNG
CHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: DNA-dependent ATPase activity; Phosphoric ester hydrolysis [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]