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The map label for this gene is yicI [H]

Identifier: 50365133

GI number: 50365133

Start: 370298

End: 372556

Strand: Direct

Name: yicI [H]

Synonym: Mfl317

Alternate gene names: 50365133

Gene position: 370298-372556 (Clockwise)

Preceding gene: 50365132

Following gene: 50365134

Centisome position: 46.68

GC content: 26.52

Gene sequence:

>2259_bases
ATGTCTATAAGAGATAATATAACAAAAAAACAATATGCATATAATTGTGTAGAACATGAAAGAATTTTTTCTATTGAGTC
AAACTATGCTATTGCATTAAGATTAAGTGACGTTTGAGAAGAAGGCAATAAGCTTTATGTGGAAGTTACTTTTAATAATT
TTCAAAAAGCTTATTTATCATTTGCTGAATATGAAAATGGAATAGTTAATATAAGATATTGACAAAAACAAATCCCAGTA
AATAGATATTATGATAAAAACCATGAAAACATGGTCACAACAAAAATAAAATATAAAAATGATAAAAATGAAATAGTAAT
TTCATTAAAAAATGGTGAAAATATTATTATTACAAAAAATAAATTCCAATTAGCATTAGTAGACGTTAATGGTGAGATAA
AAACAAAAACTTCTTTAAGACCAGGATGAGATCATTTAGAAGGATATTGCACACCACCTTTAGGATTTAAAATTGATGAT
AATATTCAAAAGCCATTTATGACAATGCAGTTAGCTAGTGAAGAGTTAATTTATGGGTTAGGTGAAAAATTTAACAATTT
TGTTAAAAACGGTGTTCAATCAACTATTTTTAATGTAGATAATGAAGCTGTTTCAAATGGTGATTATGCTTATTCAGGAG
TACCTTTAGTATATTCTTCAAGAAATTGAGGATTACTATTAAATACAGCTCATAAAACAGAGTGAGAAATTGGTTCACCA
ACAACCGAAAGTTTATCGTTTATGTCTACAGAAGAATGTTTAGATATAATTTTATTTTCAGGAGATTCATTAAAAGATTT
AGTTAAACAATATACTTTATTTACAGGTAGAATAACTGGTGTTCCAGATGAAGCCTATGGATTATGATTAAACAGACTTT
ATTATCATAATAAAAAAGAATTATTTACTGAAATTGAAAATTCAATAAAAAATGAGTATCCAATAGATGTATTTACATTG
GATCCAAAATGAATCAAAAATAGATATACAAAATCATGTAATTTTGAATTCAATGACGATCAATTTGGAGATTTAGAAAC
AATGCTTAGCGAAGTCCACGAAAAAGGATTTAAAATGTGTTTCTGAATAAACCCTTATTTACAAATAGATAACTCTGAAA
TGTGAAATGAAGTTTACGAAAAAGGTTATCATGTTAAAAAAGCTGATGGAAGTATTGCACATATTTGAAGTGGTTTTGGT
AATTACCAAGAAACAGCTTCAGCTATAGATTTAACAAATCCAGATGCTGTAGTATATTGAAAAAATAAAATAAAAGATTT
AATGTACAAAGGTGTAGATTTTATTAAAACTGATTATGGTGATAGTGTTGATGAAGACGCTGTAATGTTTAACGGTGAAA
AAGGAACAAATTTTAAAAATGCTTATGCTGAATTATATCTAAGATATGTTTATGAAGCAACTCAAGAAGTGAAAGGTATA
GATAAAGGTTTCTGTTTATCAAGACCTGGATATATTGGAACACAAAAATATGTTGGAAAATGAGCTGGAGATTCAGCATC
AAGTTTTAATGAACTAAAAATGCAATTACTTTCTGGTTTATCAAATTCACTTTGTGGAACAGTAATGTGAGGAACTGATA
TAGGTGGCTTTTTAGATATTAACGCTAATGAAGAAGACTTGTATGCAAGATGATCACAATTTGGTTTATTGACACCTTTT
TCAAGATACCATGGTGTTGGAGCAAGAGAACCTTGATATTTTGGAGAAAAAGACTTAAATATTTCTAGAGAAGCCGCTAA
ATTAAAAAGACAATTACTTCCTTACTATAAAATCTATGAAAAAGAAGCTATTGAATCAGGATTACCAATAATAAGACCTT
TAGTTCTTGAATTCCCTAATGATACAATTGCTGCTAAAATAGATGATCAATTTATGTTGGGTGAAAATATTATGGTTGCT
CCTATTTTAAGTAATAAAAAATATGAAAGACAAGTTTATTTCCCTGAAGGAAACTGAATTGATTTTTCAGATAAAAAAAT
TTATGAAGGTAACAAAAAATATAATATTGATTGTCCAATTGAAAAAATACTAATCTTTGTTAAAGAAAATTCAATTATAC
CTATGATTAAAAATCCTATGTATAAATTTAACAATATAGATAATGAAAAAATTAAATTAAGAATCTATGGAAATGTTTTA
AATGAAACATTAAAATTTAGAATAAATGACAAAGACTACTCTGTTGAAGTGAGAGACAACAAAATAGTTAATGAAAATGA
AAAATTCGAAGTAGAATAA

Upstream 100 bases:

>100_bases
AATATTTAAATTTTGGATACATAGCAAACGTTTAAAATCTTGTTACTACAAGTTACACTCACTAAAACCAATTTTATAAT
AATAATGTGAGGTGACAAAA

Downstream 100 bases:

>100_bases
GGTGAAATTTATGGCAGAAAGCAAAAACATCAAAATTTATGCTCCCGTAGATTGTCATGTAGAAGATATAAAAGAATTAA
ATGATGGGGTTTTTAGTGAA

Product: alpha glucosidase/alpha-xylosidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 752; Mature: 751

Protein sequence:

>752_residues
MSIRDNITKKQYAYNCVEHERIFSIESNYAIALRLSDVWEEGNKLYVEVTFNNFQKAYLSFAEYENGIVNIRYWQKQIPV
NRYYDKNHENMVTTKIKYKNDKNEIVISLKNGENIIITKNKFQLALVDVNGEIKTKTSLRPGWDHLEGYCTPPLGFKIDD
NIQKPFMTMQLASEELIYGLGEKFNNFVKNGVQSTIFNVDNEAVSNGDYAYSGVPLVYSSRNWGLLLNTAHKTEWEIGSP
TTESLSFMSTEECLDIILFSGDSLKDLVKQYTLFTGRITGVPDEAYGLWLNRLYYHNKKELFTEIENSIKNEYPIDVFTL
DPKWIKNRYTKSCNFEFNDDQFGDLETMLSEVHEKGFKMCFWINPYLQIDNSEMWNEVYEKGYHVKKADGSIAHIWSGFG
NYQETASAIDLTNPDAVVYWKNKIKDLMYKGVDFIKTDYGDSVDEDAVMFNGEKGTNFKNAYAELYLRYVYEATQEVKGI
DKGFCLSRPGYIGTQKYVGKWAGDSASSFNELKMQLLSGLSNSLCGTVMWGTDIGGFLDINANEEDLYARWSQFGLLTPF
SRYHGVGAREPWYFGEKDLNISREAAKLKRQLLPYYKIYEKEAIESGLPIIRPLVLEFPNDTIAAKIDDQFMLGENIMVA
PILSNKKYERQVYFPEGNWIDFSDKKIYEGNKKYNIDCPIEKILIFVKENSIIPMIKNPMYKFNNIDNEKIKLRIYGNVL
NETLKFRINDKDYSVEVRDNKIVNENEKFEVE

Sequences:

>Translated_752_residues
MSIRDNITKKQYAYNCVEHERIFSIESNYAIALRLSDV*EEGNKLYVEVTFNNFQKAYLSFAEYENGIVNIRY*QKQIPV
NRYYDKNHENMVTTKIKYKNDKNEIVISLKNGENIIITKNKFQLALVDVNGEIKTKTSLRPG*DHLEGYCTPPLGFKIDD
NIQKPFMTMQLASEELIYGLGEKFNNFVKNGVQSTIFNVDNEAVSNGDYAYSGVPLVYSSRN*GLLLNTAHKTE*EIGSP
TTESLSFMSTEECLDIILFSGDSLKDLVKQYTLFTGRITGVPDEAYGL*LNRLYYHNKKELFTEIENSIKNEYPIDVFTL
DPK*IKNRYTKSCNFEFNDDQFGDLETMLSEVHEKGFKMCF*INPYLQIDNSEM*NEVYEKGYHVKKADGSIAHI*SGFG
NYQETASAIDLTNPDAVVY*KNKIKDLMYKGVDFIKTDYGDSVDEDAVMFNGEKGTNFKNAYAELYLRYVYEATQEVKGI
DKGFCLSRPGYIGTQKYVGK*AGDSASSFNELKMQLLSGLSNSLCGTVM*GTDIGGFLDINANEEDLYAR*SQFGLLTPF
SRYHGVGAREP*YFGEKDLNISREAAKLKRQLLPYYKIYEKEAIESGLPIIRPLVLEFPNDTIAAKIDDQFMLGENIMVA
PILSNKKYERQVYFPEGN*IDFSDKKIYEGNKKYNIDCPIEKILIFVKENSIIPMIKNPMYKFNNIDNEKIKLRIYGNVL
NETLKFRINDKDYSVEVRDNKIVNENEKFEVE
>Mature_751_residues
SIRDNITKKQYAYNCVEHERIFSIESNYAIALRLSDV*EEGNKLYVEVTFNNFQKAYLSFAEYENGIVNIRY*QKQIPVN
RYYDKNHENMVTTKIKYKNDKNEIVISLKNGENIIITKNKFQLALVDVNGEIKTKTSLRPG*DHLEGYCTPPLGFKIDDN
IQKPFMTMQLASEELIYGLGEKFNNFVKNGVQSTIFNVDNEAVSNGDYAYSGVPLVYSSRN*GLLLNTAHKTE*EIGSPT
TESLSFMSTEECLDIILFSGDSLKDLVKQYTLFTGRITGVPDEAYGL*LNRLYYHNKKELFTEIENSIKNEYPIDVFTLD
PK*IKNRYTKSCNFEFNDDQFGDLETMLSEVHEKGFKMCF*INPYLQIDNSEM*NEVYEKGYHVKKADGSIAHI*SGFGN
YQETASAIDLTNPDAVVY*KNKIKDLMYKGVDFIKTDYGDSVDEDAVMFNGEKGTNFKNAYAELYLRYVYEATQEVKGID
KGFCLSRPGYIGTQKYVGK*AGDSASSFNELKMQLLSGLSNSLCGTVM*GTDIGGFLDINANEEDLYAR*SQFGLLTPFS
RYHGVGAREP*YFGEKDLNISREAAKLKRQLLPYYKIYEKEAIESGLPIIRPLVLEFPNDTIAAKIDDQFMLGENIMVAP
ILSNKKYERQVYFPEGN*IDFSDKKIYEGNKKYNIDCPIEKILIFVKENSIIPMIKNPMYKFNNIDNEKIKLRIYGNVLN
ETLKFRINDKDYSVEVRDNKIVNENEKFEVE

Specific function: Can catalyzes the transfer of alpha-xylosyl residue from alpha-xyloside to xylose, glucose, mannose, fructose, maltose, isomaltose, nigerose, kojibiose, sucrose and trehalose [H]

COG id: COG1501

COG function: function code G; Alpha-glucosidases, family 31 of glycosyl hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 31 family [H]

Homologues:

Organism=Homo sapiens, GI88900491, Length=479, Percent_Identity=27.348643006263, Blast_Score=150, Evalue=5e-36,
Organism=Homo sapiens, GI38202257, Length=479, Percent_Identity=27.348643006263, Blast_Score=150, Evalue=6e-36,
Organism=Homo sapiens, GI66346737, Length=469, Percent_Identity=28.1449893390192, Blast_Score=136, Evalue=7e-32,
Organism=Homo sapiens, GI119393895, Length=657, Percent_Identity=23.2876712328767, Blast_Score=124, Evalue=4e-28,
Organism=Homo sapiens, GI119393893, Length=657, Percent_Identity=23.2876712328767, Blast_Score=124, Evalue=4e-28,
Organism=Homo sapiens, GI119393891, Length=657, Percent_Identity=23.2876712328767, Blast_Score=124, Evalue=4e-28,
Organism=Homo sapiens, GI310115361, Length=242, Percent_Identity=29.3388429752066, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI221316699, Length=242, Percent_Identity=29.7520661157025, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI157364974, Length=409, Percent_Identity=23.2273838630807, Blast_Score=81, Evalue=3e-15,
Organism=Escherichia coli, GI2367256, Length=569, Percent_Identity=29.3497363796134, Blast_Score=243, Evalue=4e-65,
Organism=Escherichia coli, GI2367323, Length=566, Percent_Identity=23.1448763250883, Blast_Score=126, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17560800, Length=473, Percent_Identity=26.6384778012685, Blast_Score=147, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17560798, Length=473, Percent_Identity=26.6384778012685, Blast_Score=147, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI71991189, Length=471, Percent_Identity=27.1762208067941, Blast_Score=127, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI71985706, Length=241, Percent_Identity=27.3858921161826, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI32563849, Length=218, Percent_Identity=26.605504587156, Blast_Score=76, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6319706, Length=531, Percent_Identity=24.6704331450094, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24643749, Length=591, Percent_Identity=22.673434856176, Blast_Score=108, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24643753, Length=591, Percent_Identity=22.673434856176, Blast_Score=108, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24643751, Length=591, Percent_Identity=22.673434856176, Blast_Score=108, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24643746, Length=591, Percent_Identity=22.673434856176, Blast_Score=108, Evalue=2e-23,
Organism=Drosophila melanogaster, GI21357605, Length=591, Percent_Identity=22.673434856176, Blast_Score=108, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011013
- InterPro:   IPR000322
- InterPro:   IPR017853 [H]

Pfam domain/function: PF01055 Glyco_hydro_31 [H]

EC number: NA

Molecular weight: Translated: 84022; Mature: 83891

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIRDNITKKQYAYNCVEHERIFSIESNYAIALRLSDVEEGNKLYVEVTFNNFQKAYLSF
CCCCCCCCHHHHHHHHHCCCEEEEECCCEEEEEEEECCCCCCEEEEEEEECCHHHHHHHH
AEYENGIVNIRYQKQIPVNRYYDKNHENMVTTKIKYKNDKNEIVISLKNGENIIITKNKF
HHHCCCEEEEEEECCCCCHHCCCCCCCCEEEEEEEEECCCCEEEEEEECCCEEEEECCCE
QLALVDVNGEIKTKTSLRPGDHLEGYCTPPLGFKIDDNIQKPFMTMQLASEELIYGLGEK
EEEEEECCCCEEEECCCCCCCCCCCEECCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHH
FNNFVKNGVQSTIFNVDNEAVSNGDYAYSGVPLVYSSRNGLLLNTAHKTEEIGSPTTESL
HHHHHHCCHHHHHEECCCHHCCCCCEEECCCEEEEECCCCEEEECCCCHHHCCCCCHHHH
SFMSTEECLDIILFSGDSLKDLVKQYTLFTGRITGVPDEAYGLLNRLYYHNKKELFTEIE
HHCCHHHHEEEEEECCCCHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHH
NSIKNEYPIDVFTLDPKIKNRYTKSCNFEFNDDQFGDLETMLSEVHEKGFKMCFINPYLQ
HHHCCCCCEEEEEECCHHHCCCCCCCCCEECCCCCCCHHHHHHHHHHCCCEEEEECCEEE
IDNSEMNEVYEKGYHVKKADGSIAHISGFGNYQETASAIDLTNPDAVVYKNKIKDLMYKG
ECCCHHHHHHHCCCEEEECCCCEEEEECCCCHHHHHCEEECCCCCEEEEHHHHHHHHHCC
VDFIKTDYGDSVDEDAVMFNGEKGTNFKNAYAELYLRYVYEATQEVKGIDKGFCLSRPGY
CHHEECCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCC
IGTQKYVGKAGDSASSFNELKMQLLSGLSNSLCGTVMGTDIGGFLDINANEEDLYARSQF
CCCHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEEECCCHHHHHHHCCC
GLLTPFSRYHGVGAREPYFGEKDLNISREAAKLKRQLLPYYKIYEKEAIESGLPIIRPLV
CCCCCHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHH
LEFPNDTIAAKIDDQFMLGENIMVAPILSNKKYERQVYFPEGNIDFSDKKIYEGNKKYNI
EECCCCEEEEEECCCEEECCCEEEEEEECCCCCCEEEECCCCCCCCCCCEEECCCCEEEE
DCPIEKILIFVKENSIIPMIKNPMYKFNNIDNEKIKLRIYGNVLNETLKFRINDKDYSVE
CCCHHHEEEEEECCCCCEEECCCCHHCCCCCCCEEEEEEECCHHCCEEEEEECCCCEEEE
VRDNKIVNENEKFEVE
ECCCEEECCCCCEECC
>Mature Secondary Structure 
SIRDNITKKQYAYNCVEHERIFSIESNYAIALRLSDVEEGNKLYVEVTFNNFQKAYLSF
CCCCCCCHHHHHHHHHCCCEEEEECCCEEEEEEEECCCCCCEEEEEEEECCHHHHHHHH
AEYENGIVNIRYQKQIPVNRYYDKNHENMVTTKIKYKNDKNEIVISLKNGENIIITKNKF
HHHCCCEEEEEEECCCCCHHCCCCCCCCEEEEEEEEECCCCEEEEEEECCCEEEEECCCE
QLALVDVNGEIKTKTSLRPGDHLEGYCTPPLGFKIDDNIQKPFMTMQLASEELIYGLGEK
EEEEEECCCCEEEECCCCCCCCCCCEECCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHH
FNNFVKNGVQSTIFNVDNEAVSNGDYAYSGVPLVYSSRNGLLLNTAHKTEEIGSPTTESL
HHHHHHCCHHHHHEECCCHHCCCCCEEECCCEEEEECCCCEEEECCCCHHHCCCCCHHHH
SFMSTEECLDIILFSGDSLKDLVKQYTLFTGRITGVPDEAYGLLNRLYYHNKKELFTEIE
HHCCHHHHEEEEEECCCCHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHH
NSIKNEYPIDVFTLDPKIKNRYTKSCNFEFNDDQFGDLETMLSEVHEKGFKMCFINPYLQ
HHHCCCCCEEEEEECCHHHCCCCCCCCCEECCCCCCCHHHHHHHHHHCCCEEEEECCEEE
IDNSEMNEVYEKGYHVKKADGSIAHISGFGNYQETASAIDLTNPDAVVYKNKIKDLMYKG
ECCCHHHHHHHCCCEEEECCCCEEEEECCCCHHHHHCEEECCCCCEEEEHHHHHHHHHCC
VDFIKTDYGDSVDEDAVMFNGEKGTNFKNAYAELYLRYVYEATQEVKGIDKGFCLSRPGY
CHHEECCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCC
IGTQKYVGKAGDSASSFNELKMQLLSGLSNSLCGTVMGTDIGGFLDINANEEDLYARSQF
CCCHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEEECCCHHHHHHHCCC
GLLTPFSRYHGVGAREPYFGEKDLNISREAAKLKRQLLPYYKIYEKEAIESGLPIIRPLV
CCCCCHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHH
LEFPNDTIAAKIDDQFMLGENIMVAPILSNKKYERQVYFPEGNIDFSDKKIYEGNKKYNI
EECCCCEEEEEECCCEEECCCEEEEEEECCCCCCEEEECCCCCCCCCCCEEECCCCEEEE
DCPIEKILIFVKENSIIPMIKNPMYKFNNIDNEKIKLRIYGNVLNETLKFRINDKDYSVE
CCCHHHEEEEEECCCCCEEECCCCHHCCCCCCCEEEEEEECCHHCCEEEEEECCCCEEEE
VRDNKIVNENEKFEVE
ECCCEEECCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]