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The map label for this gene is add [H]

Identifier: 50365031

GI number: 50365031

Start: 240069

End: 241073

Strand: Reverse

Name: add [H]

Synonym: Mfl215

Alternate gene names: 50365031

Gene position: 241073-240069 (Counterclockwise)

Preceding gene: 50365041

Following gene: 50365019

Centisome position: 30.39

GC content: 25.77

Gene sequence:

>1005_bases
ATGAAAAATATTGAAAATATGCCAAAAATTGAATTACATGTACATATAGAAGGGACTTTAGAAGCTAAAACAGTTTTAGC
TAAAATTGAACAAAAGCAATTAAATTTTGATCCTATGTACTTAGAAAAATTATCAAAGCCACCCGTTTTTACTAGTTTGT
CTGATTTTTTAAAAGACTACTATAAAAATATGGCTGTCTTAGAGAATCAACAAGACTTTTTTGATTTAGCTTGAAATCAT
TTGAAAAATGCAAAAAAACAAAATGTTATCTATACTGAGATTTTCTTTGATCCACAACCTCACATTAAACGAGGCATTCA
TTTAGATGATGTTATAGATGGTTTGTATCAAGCTTTAGAAAAAGCAGAAAAAGAACTTGATTTAAAAGCAAAGTTAATTA
TGTGTTTTTTGAAAGATGAAAGCGTTGATGAAGCTTTAAATATTTTAGATATGTCAAAACTTGCTATTGAAAATAAAAAA
ATTGTTGGAATAGGTTTTGATTCTAATGAAATTGAAAACTGAGCAGCCATTTTTAAACCAGTTGTTGATAAAGCAAGGAA
TCTAGGCTTAAATGTAACAACACATGCTGCTGAAAATAGTTTTGAACAAGACCCAATTGAGGTTATAAATATTTTAAACC
CTGATAGAATTGATCATGGATTATATATTCATAAAAGTTTAGAAGCATTAAAATTAGTTAAAGAAAAAGAAATACATTTA
TCATTATGTCCTTTGCCTAATTTTTACTCAAAAGCTTGACTTGACCCAAAAACATTTCCTATTCAAGTTTTCTTAGACAA
TGATATTTCTTTTTCAATAAATTCTGATGACCCTGCATATTTTGGACCTACAACTTTGAATGATAACTATCTTTTAGTTA
ATCAAAATAATAAAATATCTGAAGAAAAATGAAAAAATCTATTATTAAAAACATTAAATTCAACATTCACTAATACTGAA
GAAAAAGAATATTTAAAAGAAAAAATAGAAAACTACTTCAAATAA

Upstream 100 bases:

>100_bases
TATTTTAACATAAAAAAGTAATTATATTGTGTTTCAAAAATACCTTTTGTTTATTAGTATTTTGATATTATAAGTTCATA
TTTTTAAATAAAGGAGTTGT

Downstream 100 bases:

>100_bases
AAAATGCTTATCTTACGATAAGCATTTTATTTTTAAATATTACTATTTTTTAGATTTTCTTTGTTCATCTAAGATTTTAA
TCATACGAGGTTTAATAGCT

Product: adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase [H]

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MKNIENMPKIELHVHIEGTLEAKTVLAKIEQKQLNFDPMYLEKLSKPPVFTSLSDFLKDYYKNMAVLENQQDFFDLAWNH
LKNAKKQNVIYTEIFFDPQPHIKRGIHLDDVIDGLYQALEKAEKELDLKAKLIMCFLKDESVDEALNILDMSKLAIENKK
IVGIGFDSNEIENWAAIFKPVVDKARNLGLNVTTHAAENSFEQDPIEVINILNPDRIDHGLYIHKSLEALKLVKEKEIHL
SLCPLPNFYSKAWLDPKTFPIQVFLDNDISFSINSDDPAYFGPTTLNDNYLLVNQNNKISEEKWKNLLLKTLNSTFTNTE
EKEYLKEKIENYFK

Sequences:

>Translated_334_residues
MKNIENMPKIELHVHIEGTLEAKTVLAKIEQKQLNFDPMYLEKLSKPPVFTSLSDFLKDYYKNMAVLENQQDFFDLA*NH
LKNAKKQNVIYTEIFFDPQPHIKRGIHLDDVIDGLYQALEKAEKELDLKAKLIMCFLKDESVDEALNILDMSKLAIENKK
IVGIGFDSNEIEN*AAIFKPVVDKARNLGLNVTTHAAENSFEQDPIEVINILNPDRIDHGLYIHKSLEALKLVKEKEIHL
SLCPLPNFYSKA*LDPKTFPIQVFLDNDISFSINSDDPAYFGPTTLNDNYLLVNQNNKISEEK*KNLLLKTLNSTFTNTE
EKEYLKEKIENYFK
>Mature_334_residues
MKNIENMPKIELHVHIEGTLEAKTVLAKIEQKQLNFDPMYLEKLSKPPVFTSLSDFLKDYYKNMAVLENQQDFFDLA*NH
LKNAKKQNVIYTEIFFDPQPHIKRGIHLDDVIDGLYQALEKAEKELDLKAKLIMCFLKDESVDEALNILDMSKLAIENKK
IVGIGFDSNEIEN*AAIFKPVVDKARNLGLNVTTHAAENSFEQDPIEVINILNPDRIDHGLYIHKSLEALKLVKEKEIHL
SLCPLPNFYSKA*LDPKTFPIQVFLDNDISFSINSDDPAYFGPTTLNDNYLLVNQNNKISEEK*KNLLLKTLNSTFTNTE
EKEYLKEKIENYFK

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family [H]

Homologues:

Organism=Homo sapiens, GI47078295, Length=341, Percent_Identity=24.3401759530792, Blast_Score=100, Evalue=2e-21,
Organism=Escherichia coli, GI1787910, Length=329, Percent_Identity=21.2765957446809, Blast_Score=85, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI32565969, Length=350, Percent_Identity=24.2857142857143, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17538512, Length=352, Percent_Identity=24.1477272727273, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI115537133, Length=293, Percent_Identity=24.9146757679181, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324188, Length=299, Percent_Identity=35.4515050167224, Blast_Score=165, Evalue=7e-42,
Organism=Drosophila melanogaster, GI24645260, Length=339, Percent_Identity=23.3038348082596, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001365
- InterPro:   IPR006330 [H]

Pfam domain/function: PF00962 A_deaminase [H]

EC number: =3.5.4.4 [H]

Molecular weight: Translated: 37921; Mature: 37921

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00485 A_DEAMINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNIENMPKIELHVHIEGTLEAKTVLAKIEQKQLNFDPMYLEKLSKPPVFTSLSDFLKDY
CCCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHH
YKNMAVLENQQDFFDLANHLKNAKKQNVIYTEIFFDPQPHIKRGIHLDDVIDGLYQALEK
HHHHHHHCCCHHHHHHHHHHHHHHHCCEEEEEEEECCCHHHHHCCCHHHHHHHHHHHHHH
AEKELDLKAKLIMCFLKDESVDEALNILDMSKLAIENKKIVGIGFDSNEIENAAIFKPVV
HHHHHCHHEEEEEEEECCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHH
DKARNLGLNVTTHAAENSFEQDPIEVINILNPDRIDHGLYIHKSLEALKLVKEKEIHLSL
HHHHHCCCEEEECCCCCCCCCCHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHCCCEEEE
CPLPNFYSKALDPKTFPIQVFLDNDISFSINSDDPAYFGPTTLNDNYLLVNQNNKISEEK
CCCCHHHHHHCCCCCCEEEEEECCCEEEEECCCCCCEECCCCCCCCEEEEECCCCCHHHH
KNLLLKTLNSTFTNTEEKEYLKEKIENYFK
HHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKNIENMPKIELHVHIEGTLEAKTVLAKIEQKQLNFDPMYLEKLSKPPVFTSLSDFLKDY
CCCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHH
YKNMAVLENQQDFFDLANHLKNAKKQNVIYTEIFFDPQPHIKRGIHLDDVIDGLYQALEK
HHHHHHHCCCHHHHHHHHHHHHHHHCCEEEEEEEECCCHHHHHCCCHHHHHHHHHHHHHH
AEKELDLKAKLIMCFLKDESVDEALNILDMSKLAIENKKIVGIGFDSNEIENAAIFKPVV
HHHHHCHHEEEEEEEECCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHH
DKARNLGLNVTTHAAENSFEQDPIEVINILNPDRIDHGLYIHKSLEALKLVKEKEIHLSL
HHHHHCCCEEEECCCCCCCCCCHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHCCCEEEE
CPLPNFYSKALDPKTFPIQVFLDNDISFSINSDDPAYFGPTTLNDNYLLVNQNNKISEEK
CCCCHHHHHHCCCCCCEEEEEECCCEEEEECCCCCCEECCCCCCCCEEEEECCCCCHHHH
KNLLLKTLNSTFTNTEEKEYLKEKIENYFK
HHHHHHHHHHHHCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA